Early postoperative nociceptive threshold and production of brain derived neurotrophic factor induced by plantar incision are not influenced with minocycline in a rat: Role of Spinal microglia

NeuroSignals

Volumn 24, Issue 1, 2016, Pages 15-24

  Masaki, Eiji ^a   Mizuta, Kentaro ^a   Ohtani, Norimasa ^a   Kido, Kanta ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Brain derived neurotrophic factor; Early postoperative pain; Microglia; Spinal cord

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MINOCYCLINE;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DRUG EFFECT; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INFRARED RADIATION; LATENT PERIOD; MALE; MECHANICAL STIMULATION; MICROGLIA; NOCICEPTION; NONHUMAN; PAIN ASSESSMENT; PAIN THRESHOLD; POSTOPERATIVE PAIN; PROTEIN EXPRESSION; RAT; SKIN INCISION; SPINAL CORD; SPINAL CORD DORSAL HORN; THERMAL STIMULATION; VON FREY TEST;

EID: 84961213966     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000442608     Document Type: Article

References (22)

1. Xu J, Brennan TJ: Comparison of skin incision vs. skin plus deep tissue incision on ongoing pain and spontaneous activity in dorsal horn neurons. Pain 2009;144:329-339.
2. Merighi A, Salio C, Ghirri A, Lossi L, Ferrini F, Betelli C, Bardoni R: BDNF as a pain modulator. Prog Neurobiol 2008;85:297-317.
3. Li CQ, Xu JM, Liu D, Zhang JY, Dai RP: Brain derived neurotrophic factor (BDNF) contributes to the pain hypersensitivity following surgical incision in the rats. Mol Pain 2008;4:27.
4. Coull JA, Beggs S, Boudreau D, Boivin D, Tsuda M, Inoue K, Gravel C, Salter MW, De Koninck Y: BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain. Nature 2005;438:1017-1021.
5. Trang T, Beggs S, Salter MW: Brain-derived neurotrophic factor from microglia: a molecular substrate for neuropathic pain. Neuron Glia Biol 2011;7:99-108.
6. Wang LN, Yang JP, Zhan Y, Ji FH, Wang XY, Zuo JL, Xu QN: Minocycline-induced reduction of brain-derived neurotrophic factor expression in relation to cancer-induced bone pain in rats. J Neurosci Res 2012;90:672-681.
7. Ducourneau VR, Dolique T, Hachem-Delaunay S, Miraucourt LS, Amadio A, Blaszczyk L, Jacquot F, Ly J, Devoize L, Oliet SH, Dallel R, Mothet JP, Nagy F, Fénelon VS, Voisin DL: Cancer pain is not necessarily correlated with spinal overexpression of reactive glia markers. Pain 2014;155:275-291.
8. Ito N, Obata H, Saito S: Spinal microglial expression and mechanical hypersensitivity in a postoperative pain model: comparison with a neuropathic pain model. Anesthesiology 2009;111:640-648.
9. Obata H, Eisenach JC, Hussain H, Bynum T, Vincler M: Spinal glial activation contributes to postoperative mechanical hypersensitivity in the rat. J Pain 2006;7:816-822.
10. Wen YR, Suter MR, Ji RR, Yeh GC, Wu YS, Wang KC, Kohno T, Sun WZ, Wang CC: Activation of p38 mitogen-activated protein kinase in spinal microglia contributes to incision-induced mechanical allodynia. Anesthesiology 2009;110:155-165.
11. Yaksh TL, Rudy TA: Chronic catheterization of the spinal subarachnoid space. Physiol Behav 1976;17:1031-1036.
12. Brennan TJ, Vandermeulen EP, Gebhart GF: Characterization of a rat model of incisional pain. Pain 1996;64:493-501.
13. Mei XP, Xu H, Xie C, Ren J, Zhou Y, Zhang H, Xu LX: Post-injury administration of minocycline: an effective treatment for nerve-injury induced neuropathic pain. Neurosci Res 2011;70:305-312.
14. Guan Z, Kuhn JA, Wang X, Colquitt B, Solorzano C, Vaman S, Guan AK, Evans-Reinsch Z, Braz J, Devor M, Abboud-Werner SL, Lanier LL, Lomvardas S, Basbaum AI: Injured sensory neuron-derived CSF1 induces microglial proliferation and DAP12-dependent pain. Nat Neurosci 2016;19:94-101.
15. Mannion RJ, Costigan M, Decosterd I, Amaya F, Ma QP, Holstege JC, Ji RR, Acheson A, Lindsay RM, Wilkinson GA, Woolf CJ: Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity. Proc Natl Acad Sci U S A 1999;96:9385-9390.
16. Kras JV, Weisshaar CL, Quindlen J, Winkelstein BA: Brain-derived neurotrophic factor is upregulated in the cervical dorsal root ganglia and spinal cord and contributes to the maintenance of pain from facet joint injury in the rat. J Neurosci Res 2013;91:1312-1321.
17. Zhang X, Xu Y, Wang J, Zhou Q, Pu S, Jiang W, Du D: The effect of intrathecal administration of glial activation inhibitors on dorsal horn BDNF overexpression and hind paw mechanical allodynia in spinal nerve ligated rats. J Neural Transm 2012;119:329-336.
18. Chen YW, Lin MF, Chen YC, Hung CH, Tzeng JI, Wang JJ: Exercise training attenuates postoperative pain and expression of cytokines and N-methyl-D-aspartate receptor subunit 1 in rats. Reg Anesth Pain Med 2013;38:282-288.
19. Tai K, Iwasaki H, Ikegaya S, Ueda T: Minocycline modulates cytokine and chemokine production in lipopolysaccharide-stimulated THP-1 monocytic cells by inhibiting IB kinase / phosphorylation. Transl Res. 2013;161:99-109.
20. Silva Bastos LF, Pinheiro de Oliveira AC, Magnus Schlachetzki JC, Fiebich BL. Minocycline reduces prostaglandin E synthase expression and 8-isoprostane formation in LPS-activated primary rat microglia. Immunopharmacol Immunotoxicol. 2011;33:576-580.
21. Cho IH, Chung YM, Park CK, Park SH, Lee H, Kim D, Piao ZG, Choi SY, Lee SJ, Park K, Kim JS, Jung SJ, Oh SB: Systemic administration of minocycline inhibits formalin-induced inflammatory pain in rat. Brain Res 2006;1072:208-214.
22. Kim TH, Kim HI, Kim J, Park M, Song JH: Effects of minocycline on Na+ currents in rat dorsal root ganglion neurons. Brain Res 2011;1370:34-42.