Neuropathic pain in osteoarthritis: A review of pathophysiological mechanisms and implications for treatment

Seminars in Arthritis and Rheumatism

Volumn 44, Issue 2, 2014, Pages 145-154

  Dimitroulas, Theodoros ^a   Duarte, Rui V ^a,b   Behura, Asis ^a   Kitas, George D ^c   Raphael, Jon H ^a,b  

^a RUSSELLS HALL HOSPITAL   (United Kingdom)

^b BIRMINGHAM CITY UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Agents for neuropathic pain; Central pain perception; Centralised pain; Osteoarthritis; Synovitis

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 6; LIDOCAINE; MATRIX METALLOPROTEINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROSTAGLANDIN SYNTHASE; PURINERGIC P2X3 RECEPTOR; PURINERGIC P2X4 RECEPTOR; PURINERGIC P2X7 RECEPTOR; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR; VOLTAGE GATED SODIUM CHANNEL; ANALGESIC AGENT; ANTIRHEUMATIC AGENT;

ANALGESIA; ARTHRITIS; BONE TISSUE; CALCIUM TRANSPORT; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL DEATH; CYTOKINE RELEASE; DEMYELINATION; DISEASE MODEL; GLUCOSE METABOLISM; HUMAN; HYDROTHERAPY; IMMUNE RESPONSE; MUSCULOSKELETAL PAIN; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL PLASTICITY; NEUROPATHIC PAIN; NEUROTRANSMITTER RELEASE; NEUTROPHIL CHEMOTAXIS; NOCICEPTION; NOCICEPTIVE STIMULATION; NONHUMAN; OSTEOARTHRITIS; PAIN RECEPTOR; PATHOPHYSIOLOGY; PERIAQUEDUCTAL GRAY MATTER; PHYSIOTHERAPY; PRIORITY JOURNAL; REVIEW; SENSITIZATION; SENSORY NERVE CELL; STEROID THERAPY; TRANSCUTANEOUS NERVE STIMULATION; TREATMENT INDICATION; TREATMENT RESPONSE; AGED; ANIMAL; COMORBIDITY; MIDDLE AGED; NEURALGIA; PHYSIOLOGY; RAT; TREATMENT OUTCOME;

AGED; ANALGESICS; ANIMALS; ANTIRHEUMATIC AGENTS; COMORBIDITY; DISEASE MODELS, ANIMAL; HUMANS; MIDDLE AGED; NEURALGIA; OSTEOARTHRITIS; PAIN MANAGEMENT; PAIN PERCEPTION; RATS; TREATMENT OUTCOME;

EID: 84927573799     PISSN: 00490172     EISSN: 1532866X     Source Type: Journal    
DOI: 10.1016/j.semarthrit.2014.05.011     Document Type: Review

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