Mono-Iodoacetate-Induced Histologic Changes in Subchondral Bone and Articular Cartilage of Rat Femorotibial Joints: AN Animal Model of Osteoarthritis

Toxicologic Pathology

Volumn 31, Issue 6, 2003, Pages 619-624

  Guzman, Roberto E ^a   Evans, Mark G ^a   Bove, Susan ^a   Morenko, Brandy ^a   Kilgore, Kenneth ^a  

^a PFIZER INC   (United States)

Author keywords

animal model; articular cartilage; femorotibial joint; Monoiodoacetate; osteoarthritis; osteoclasts; subchondral bone

Indexed keywords

IODOACETIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BONE CYST; BONE REMODELING; CARTILAGE CELL; CELL ACTIVITY; CELL COUNT; CELL DEATH; CELL DEGENERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMUR CONDYLE; FIBROSIS; HEMATOPOIETIC CELL; HISTOPATHOLOGY; INJECTION; KNEE; MALE; NONHUMAN; OSTEOARTHRITIS; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; OSTEOSCLEROSIS; PRIORITY JOURNAL; RAT; THICKNESS; TIBIA;

ANIMALS; ARTHRITIS, EXPERIMENTAL; BONE AND BONES; BONE REMODELING; CARTILAGE; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FEMUR HEAD; HINDLIMB; INJECTIONS, INTRA-ARTICULAR; IODOACETATES; MALE; OSTEOARTHRITIS; RATS; RATS, WISTAR; TIBIA;

ANIMALIA; RODENTIA;

EID: 0242552331     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230390241800     Document Type: Article

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