Targeting p97 to disrupt protein homeostasis in cancer

Frontiers in Oncology

Volumn 6, Issue AUG, 2016, Pages

  Vekaria, Pratikkumar Harsukhbhai ^a   Home, Trisha ^a   Weir, Scott ^b   Schoenen, Frank J ^c   Rao, Rekha ^a  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b UNIVERSITY OF KANSAS CANCER CENTER   (United States)

^c UNIVERSITY OF KANSAS   (United States)

Author keywords

Cancer; CDC48; ER stress; ERAD; P97 inhibitors; Proteotoxic stress; VCP

Indexed keywords

ADENOSINE TRIPHOSPHATASE; EEYARESTATIN 1; HEAT SHOCK PROTEIN 90; MITOGEN ACTIVATED PROTEIN KINASE; N ETHYLMALEIMIDE SENSITIVE FACTOR; PROTEIN INHIBITOR; PROTEIN P97; PROTEIN TRANSLOCASE; REACTIVE OXYGEN METABOLITE; RIBOSOME PROTEIN; UNCLASSIFIED DRUG; VALOSIN CONTAINING PROTEIN;

ANTINEOPLASTIC ACTIVITY; ATPASE ACTIVITY ASSAY; CELL DEATH; CELLULAR STRESS RESPONSE; DNA DAMAGE; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; GROWTH INHIBITION; HUMAN; NEOPLASM; OXIDATIVE STRESS; PHENOTYPE; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN HOMEOSTASIS; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; SHORT SURVEY; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; TUMOR MICROENVIRONMENT; UBIQUITINATION; UNFOLDED PROTEIN RESPONSE;

EID: 84990059362     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2016.00181     Document Type: Short Survey

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