Activation of IRE1α-XBP1 pathway induces cell proliferation and invasion in colorectal carcinoma

Biochemical and Biophysical Research Communications

Volumn 470, Issue 1, 2016, Pages 75-81

  Jin, Chun ^a   Jin, Zhao ^b   Chen, Nian Zhao ^c   Lu, Min ^a   Liu, Chang Bao ^a   Hu, Wan Le ^a   Zheng, Chen Guo ^a  

^a THE SECOND AFFILIATED HOSPITAL AND YUYING CHILDREN S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^b Integrated Traditional Chinese and Western Medicine Hospital of Wenzhou   (China)

^c Wenzhou Chinese Medical Hospital   (China)

Author keywords

Cell proliferation; Colorectal carcinoma; Epithelial to mesenchymal transition; ER stress; IRE1

Indexed keywords

CYCLIN D1; MESSENGER RNA; NERVE CELL ADHESION MOLECULE; PROTEIN IRE1; PROTEIN IRE1 ALPHA; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; UVOMORULIN; X BOX BINDING PROTEIN 1; DNA BINDING PROTEIN; ERN1 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; REGULATORY FACTOR X TRANSCRIPTION FACTORS; RIBONUCLEASE; TRANSCRIPTION FACTOR; TUMOR MARKER;

ARTICLE; AUTOPHOSPHORYLATION; CANCER GROWTH; CANCER PROGNOSIS; CANCER SURVIVAL; CELL PROLIFERATION; CELL VIABILITY; CHROMATIN IMMUNOPRECIPITATION; COLORECTAL CARCINOMA; CONTROLLED STUDY; ECTOPIC EXPRESSION; ENZYME ACTIVATION; ENZYME ACTIVITY; EPITHELIAL MESENCHYMAL TRANSITION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; METASTASIS; MITOSIS; OVERALL SURVIVAL; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SURVIVAL RATE; SURVIVAL TIME; TRANSACTIVATION; TUMOR INVASION; WESTERN BLOTTING; CHINA; COLORECTAL TUMOR; EPIDEMIOLOGY; FEMALE; MALE; METABOLISM; MORTALITY; PATHOLOGY; PREVALENCE; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS;

BIOMARKERS, TUMOR; CELL PROLIFERATION; CHINA; COLORECTAL NEOPLASMS; DNA-BINDING PROTEINS; ENDORIBONUCLEASES; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HUMANS; MALE; NEOPLASM INVASIVENESS; PREVALENCE; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TRANSCRIPTION FACTORS;

EID: 84956588404     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.12.119     Document Type: Article

References (24)

1. D.A. Lieberman Clinical practice. Screening for colorectal cancer N. Engl. J. Med. 361 2009 1179 1187
2. L. Niederreiter, T.M. Fritz, T.E. Adolph, A.M. Krismer, F.A. Offner, M. Tschurtschenthaler, M.B. Flak, S. Hosomi, M.F. Tomczak, N.C. Kaneider, E. Sarcevic, S.L. Kempster, T. Raine, D. Esser, P. Rosenstiel, K. Kohno, T. Iwawaki, H. Tilg, R.S. Blumberg, and A. Kaser ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells J. Exp. Med. 210 2013 2041 2056
3. A. Amcheslavsky, J. Jiang, and Y.T. Ip Tissue damage-induced intestinal stem cell division in Drosophila Cell Stem Cell 4 2009 49 61
4. S.J. Cronin, N.T. Nehme, S. Limmer, S. Liegeois, J.A. Pospisilik, D. Schramek, A. Leibbrandt, M. Simoes Rde, S. Gruber, U. Puc, I. Ebersberger, T. Zoranovic, G.G. Neely, A. von Haeseler, D. Ferrandon, and J.M. Penninger Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection Science 325 2009 340 343
5. H. Jiang, P.H. Patel, A. Kohlmaier, M.O. Grenley, D.G. McEwen, and B.A. Edgar Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut Cell 137 2009 1343 1355
6. A. Kuraishy, M. Karin, and S.I. Grivennikov Tumor promotion via injury- and death-induced inflammation Immunity 35 2011 467 477
7. W.Z. Qin, Q.L. Li, W.F. Chen, M.D. Xu, Y.Q. Zhang, Y.S. Zhong, L.L. Ma, J.W. Hu, M.Y. Cai, M.J. He, L.Q. Yao, and P.H. Zhou Overexpression of fibrinogen-like protein 2 induces epithelial-to-mesenchymal transition and promotes tumor progression in colorectal carcinoma Med. Oncol. 31 2014 181
8. M. Schroder, and R.J. Kaufman The mammalian unfolded protein response Annu. Rev. Biochem. 74 2005 739 789
9. D.J. Todd, A.H. Lee, and L.H. Glimcher The endoplasmic reticulum stress response in immunity and autoimmunity Nat. Rev. Immunol. 8 2008 663 674
10. P. Walter, and D. Ron The unfolded protein response: from stress pathway to homeostatic regulation Science 334 2011 1081 1086
11. A. Kaser, and R.S. Blumberg Introduction: the unfolded protein response's role in disease pathophysiology Semin. Immunopathol. 35 2013 255 257
12. D. Ron, and P. Walter Signal integration in the endoplasmic reticulum unfolded protein response Nat. Rev. Mol. Cell Biol. 8 2007 519 529
13. K. Kohno Stress-sensing mechanisms in the unfolded protein response: similarities and differences between yeast and mammals J. Biochem. 147 2010 27 33
14. C. Hetz, F. Martinon, D. Rodriguez, and L.H. Glimcher The unfolded protein response: integrating stress signals through the stress sensor IRE1alpha Physiol. Rev. 91 2011 1219 1243
15. T. Fujimoto, K. Yoshimatsu, K. Watanabe, H. Yokomizo, T. Otani, A. Matsumoto, G. Osawa, M. Onda, and K. Ogawa Overexpression of human X-box binding protein 1 (XBP-1) in colorectal adenomas and adenocarcinomas Anticancer Res. 27 2007 127 131
16. H. Kim, A. Bhattacharya, and L. Qi Endoplasmic reticulum quality control in cancer: Friend or foe Semin. Cancer Biol. 33 2015 25 33
17. T. Bagratuni, P. Wu, D. Gonzalez de Castro, E.L. Davenport, N.J. Dickens, B.A. Walker, K. Boyd, D.C. Johnson, W. Gregory, G.J. Morgan, and F.E. Davies XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments Blood 116 2010 250 253
18. C. Wang, K. Jiang, D. Gao, X. Kang, C. Sun, Q. Zhang, Y. Li, L. Sun, S. Zhang, K. Guo, and Y. Liu Clusterin protects hepatocellular carcinoma cells from endoplasmic reticulum stress induced apoptosis through GRP78 PLoS One 8 2013 e55981
19. M. Shao, B. Shan, Y. Liu, Y. Deng, C. Yan, Y. Wu, T. Mao, Y. Qiu, Y. Zhou, S. Jiang, W. Jia, J. Li, L. Rui, and L. Yang Hepatic IRE1alpha regulates fasting-induced metabolic adaptive programs through the XBP1s-PPARalpha axis signalling Nat. Commun. 5 2014 3528
20. Q.L. Li, F.M. Gu, Z. Wang, J.H. Jiang, L.Q. Yao, C.J. Tan, X.Y. Huang, A.W. Ke, Z. Dai, J. Fan, and J. Zhou Activation of PI3K/AKT and MAPK pathway through a PDGFRbeta-dependent feedback loop is involved in rapamycin resistance in hepatocellular carcinoma PLoS One 7 2012 e33379
21. J.H. Lin, H. Li, D. Yasumura, H.R. Cohen, C. Zhang, B. Panning, K.M. Shokat, M.M. Lavail, and P. Walter IRE1 signaling affects cell fate during the unfolded protein response Science 318 2007 944 949
22. S. Wang, Z. Chen, V. Lam, J. Han, J. Hassler, B.N. Finck, N.O. Davidson, and R.J. Kaufman IRE1alpha-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis Cell Metab. 16 2012 473 486
23. Y. Deng, Z.V. Wang, C. Tao, N. Gao, W.L. Holland, A. Ferdous, J.J. Repa, G. Liang, J. Ye, M.A. Lehrman, J.A. Hill, J.D. Horton, and P.E. Scherer The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism J. Clin. Investig. 123 2013 455 468
24. Y. Zhou, J. Lee, C.M. Reno, C. Sun, S.W. Park, J. Chung, S.J. Fisher, M.F. White, S.B. Biddinger, and U. Ozcan Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction Nat. Med. 17 2011 356 365