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Volumn 6, Issue 19, 2015, Pages 17725-17737

Regulation of VCP/p97 demonstrates the critical balance between cell death and epithelial-mesenchymal transition (EMT) downstream of ER stress

Author keywords

EMT; ER stress; ERAD; Invasion; Metastasis; Migration; p97

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; EEYARESTATIN I; PROTEIN INHIBITOR; PROTEIN KINASE B INHIBITOR; UNCLASSIFIED DRUG; VALOSIN CONTAINING PROTEIN; ADENOSINE TRIPHOSPHATASE; CDC48 PROTEIN; CELL CYCLE PROTEIN; SMALL INTERFERING RNA;

EID: 84938244091     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3918     Document Type: Article
Times cited : (30)

References (49)
  • 1
    • 35748948975 scopus 로고    scopus 로고
    • In and out of the ER: protein folding, quality control, degradation, and related human diseases
    • Hebert DN, Molinari M. In and out of the ER: protein folding, quality control, degradation, and related human diseases. Physiological Reviews. 2007; 87: 1377-1408.
    • (2007) Physiological Reviews , vol.87 , pp. 1377-1408
    • Hebert, D.N.1    Molinari, M.2
  • 3
    • 0346096508 scopus 로고    scopus 로고
    • Quality control in the endoplasmic reticulum protein factory
    • Sitia R, Braakman I. Quality control in the endoplasmic reticulum protein factory. Nature. 2003; 426: 891-894.
    • (2003) Nature , vol.426 , pp. 891-894
    • Sitia, R.1    Braakman, I.2
  • 4
    • 0035966269 scopus 로고    scopus 로고
    • XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
    • Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell. 2001; 107: 881-891.
    • (2001) Cell , vol.107 , pp. 881-891
    • Yoshida, H.1    Matsui, T.2    Yamamoto, A.3    Okada, T.4    Mori, K.5
  • 5
    • 5444222234 scopus 로고    scopus 로고
    • XBP1, a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum
    • Sriburi R, Jackowski S, Mori K, Brewer JW. XBP1, a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. Journal of Cell Biology. 2004; 167: 35-41.
    • (2004) Journal of Cell Biology , vol.167 , pp. 35-41
    • Sriburi, R.1    Jackowski, S.2    Mori, K.3    Brewer, J.W.4
  • 7
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
    • Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature. 2000; 403: 98-103.
    • (2000) Nature , vol.403 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3    Li, E.4    Xu, J.5    Yankner, B.A.6    Yuan, J.7
  • 8
    • 3042616595 scopus 로고    scopus 로고
    • A membrane protein required for dislocation of misfolded proteins from the ER
    • Lilley BN, Ploegh HL. A membrane protein required for dislocation of misfolded proteins from the ER. Nature. 2004; 429: 834-840.
    • (2004) Nature , vol.429 , pp. 834-840
    • Lilley, B.N.1    Ploegh, H.L.2
  • 10
    • 10944247870 scopus 로고    scopus 로고
    • Physical and functional interaction between dorWn and valosin-containing protein that are colocalized in ubiquitylated inclusions in neurodegenerative disorders
    • Ishigaki S, Hishikawa N, Niwa J, Iemura S, Natsume T, Hori S, Kakizuka A, Tanaka K, Sobue G. Physical and functional interaction between dorWn and valosin-containing protein that are colocalized in ubiquitylated inclusions in neurodegenerative disorders. Journal of Biological Chemistry. 2004; 279: 51376-51385.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 51376-51385
    • Ishigaki, S.1    Hishikawa, N.2    Niwa, J.3    Iemura, S.4    Natsume, T.5    Hori, S.6    Kakizuka, A.7    Tanaka, K.8    Sobue, G.9
  • 11
    • 0037986563 scopus 로고    scopus 로고
    • Vacuole-creating protein in neurodegenerative diseases in humans
    • Mizuno Y, Hori S, Kakizuka A, Okamoto K. Vacuole-creating protein in neurodegenerative diseases in humans. Neuroscience Letters. 2003; 343: 77-80.
    • (2003) Neuroscience Letters , vol.343 , pp. 77-80
    • Mizuno, Y.1    Hori, S.2    Kakizuka, A.3    Okamoto, K.4
  • 13
  • 14
    • 34548175512 scopus 로고    scopus 로고
    • Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression
    • Moustakas A, Heldin CH. Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression. Cancer Science. 2007; 98: 1512-1520.
    • (2007) Cancer Science , vol.98 , pp. 1512-1520
    • Moustakas, A.1    Heldin, C.H.2
  • 16
    • 85017013389 scopus 로고    scopus 로고
    • New insights on stress-induced epithelial phenotypic changes
    • Pallet Nicolas. New insights on stress-induced epithelial phenotypic changes. Nephrology Dialysis Transplantation. 2011; 0: 1-3.
    • (2011) Nephrology Dialysis Transplantation , pp. 1-3
    • Nicolas, P.1
  • 18
    • 77952543940 scopus 로고    scopus 로고
    • Oxidative and endoplasmic reticulum stress signaling are involved in dehydrocostuslactone-mediated apoptosis in human non-small cell lung cancer cells
    • Hung JY, Hsu YL, Ni WC, Tsai YM, Yang CJ, Kuo PL, Huang MS. Oxidative and endoplasmic reticulum stress signaling are involved in dehydrocostuslactone-mediated apoptosis in human non-small cell lung cancer cells. Lung Cancer. 2010; 68: 355-365.
    • (2010) Lung Cancer , vol.68 , pp. 355-365
    • Hung, J.Y.1    Hsu, Y.L.2    Ni, W.C.3    Tsai, Y.M.4    Yang, C.J.5    Kuo, P.L.6    Huang, M.S.7
  • 19
    • 0030779805 scopus 로고    scopus 로고
    • Establishment of human peripheral lung epithelial cell lines (HPL1) retaining differentiated characteristics and responsiveness to epidermal growth factor, hepatocyte growth factor, and transforming growth factor beta1
    • Masuda A, Kondo M, Saito T, Yatabe Y, Kobayashi T, Okamoto M et al. Establishment of human peripheral lung epithelial cell lines (HPL1) retaining differentiated characteristics and responsiveness to epidermal growth factor, hepatocyte growth factor, and transforming growth factor beta1. Cancer Res 1997; 57: 4898-904.
    • (1997) Cancer Res , vol.57 , pp. 4898-4904
    • Masuda, A.1    Kondo, M.2    Saito, T.3    Yatabe, Y.4    Kobayashi, T.5    Okamoto, M.6
  • 20
    • 84055172732 scopus 로고    scopus 로고
    • Critical role of VCP/p97 in the pathogenesis and progression of non-small cell lung carcinoma
    • Valle CW, Min T, Bodas M, Mazur S, Begum S, Tang D, Vij N. Critical role of VCP/p97 in the pathogenesis and progression of non-small cell lung carcinoma. PLoS One. 2011; 6 (12):e29073.
    • (2011) PLoS One , vol.6 , Issue.12 , pp. e29073
    • Valle, C.W.1    Min, T.2    Bodas, M.3    Mazur, S.4    Begum, S.5    Tang, D.6    Vij, N.7
  • 22
    • 79959677602 scopus 로고    scopus 로고
    • Life at the leading edge
    • Ridley AJ. Life at the leading edge. Cell. 2011; 145: 1012-1022.
    • (2011) Cell , vol.145 , pp. 1012-1022
    • Ridley, A.J.1
  • 23
    • 84871607697 scopus 로고    scopus 로고
    • Breaking away: matrix remodeling from the leading edge
    • McNiven MA. Breaking away: matrix remodeling from the leading edge. Trends in Cell Biology. 2013; 23: 16-21.
    • (2013) Trends in Cell Biology , vol.23 , pp. 16-21
    • McNiven, M.A.1
  • 24
    • 84055176150 scopus 로고    scopus 로고
    • Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression
    • Haynes J, Srivastava J, Madson N, Wittmann T, Barber DL. Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression. Molecular Biology of the Cell. 2011; 22: 4750-4764.
    • (2011) Molecular Biology of the Cell , vol.22 , pp. 4750-4764
    • Haynes, J.1    Srivastava, J.2    Madson, N.3    Wittmann, T.4    Barber, D.L.5
  • 25
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. Journal of Clinical Investigation. 2009; 119 (6):1420-1428.
    • (2009) Journal of Clinical Investigation , vol.119 , Issue.6 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 26
    • 52449091004 scopus 로고    scopus 로고
    • Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties
    • Aug 27
    • Levina V, Marrangoni AM, DeMarco R, Gorelik E, Lokshin AE. Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties. PLoS One. 2008 Aug 27; 3(8):e3077.
    • (2008) PLoS One , vol.3 , Issue.8 , pp. e3077
    • Levina, V.1    Marrangoni, A.M.2    DeMarco, R.3    Gorelik, E.4    Lokshin, A.E.5
  • 27
    • 77954955537 scopus 로고    scopus 로고
    • The emerging role of the phosphatidylinositol 3 - kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogensis
    • Martelli AM, Evangelisti C, Chiarini F, Grimaldi C, Cappellini A, Ognibene A, McCubrey JA. The emerging role of the phosphatidylinositol 3 - kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogensis. Biochimica et Biophysica Acta. 2010; 1803: 991-1002.
    • (2010) Biochimica et Biophysica Acta , vol.1803 , pp. 991-1002
    • Martelli, A.M.1    Evangelisti, C.2    Chiarini, F.3    Grimaldi, C.4    Cappellini, A.5    Ognibene, A.6    McCubrey, J.A.7
  • 29
    • 0038386613 scopus 로고    scopus 로고
    • Src family kinases in tumor progression and metastasis
    • Summy JM, Gallick GE. Src family kinases in tumor progression and metastasis. Cancer Metastasis Reviews. 2003; 22: 337-358.
    • (2003) Cancer Metastasis Reviews , vol.22 , pp. 337-358
    • Summy, J.M.1    Gallick, G.E.2
  • 31
    • 4444232905 scopus 로고    scopus 로고
    • The unfolded protein response: a stress signaling pathway of the endoplasmic reticulum
    • Shen X, Zhang K, Kaufman RJ. The unfolded protein response: a stress signaling pathway of the endoplasmic reticulum. Journal of Chemical Neuroanatomy. 2004; 28: 79-92.
    • (2004) Journal of Chemical Neuroanatomy , vol.28 , pp. 79-92
    • Shen, X.1    Zhang, K.2    Kaufman, R.J.3
  • 34
    • 1642309633 scopus 로고    scopus 로고
    • Molecular perspectives on p97-VCP: progress in understanding its structure and diverse biological functions
    • Wang Q, Song C, Li CC. Molecular perspectives on p97-VCP: progress in understanding its structure and diverse biological functions. Journal of Structural Biology. 2004; 146: 44-57.
    • (2004) Journal of Structural Biology , vol.146 , pp. 44-57
    • Wang, Q.1    Song, C.2    Li, C.C.3
  • 35
    • 30344460667 scopus 로고    scopus 로고
    • The role of p97/Cdc48p in endoplasmic reticulum-associated degradation: from the immune system to yeast
    • Bar-Nun S. The role of p97/Cdc48p in endoplasmic reticulum-associated degradation: from the immune system to yeast. Current Topics in Microbiology and Immunology. 2005; 300: 95-125.
    • (2005) Current Topics in Microbiology and Immunology , vol.300 , pp. 95-125
    • Bar-Nun, S.1
  • 36
    • 33750528166 scopus 로고    scopus 로고
    • Valosin-containing Protein (p97) Is a Regulator of Endoplasmic Reticulum Stress and of the Degradation of N-End Rule and Ubiquitin-Fusion Degradation Pathway Substrates in Mammalian Cells
    • Wójcik C, Rowicka M, Kudlicki A, Nowis D, McConnell E, Kujawa M, DeMartino GN. et al. Valosin-containing Protein (p97) Is a Regulator of Endoplasmic Reticulum Stress and of the Degradation of N-End Rule and Ubiquitin-Fusion Degradation Pathway Substrates in Mammalian Cells. Molecular Biology of the Cell. 2006; 17: 4606-4618.
    • (2006) Molecular Biology of the Cell , vol.17 , pp. 4606-4618
    • Wójcik, C.1    Rowicka, M.2    Kudlicki, A.3    Nowis, D.4    McConnell, E.5    Kujawa, M.6    DeMartino, G.N.7
  • 38
    • 33646373219 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53
    • Li J, Lee B, Lee AS. Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53. Journal of Biological Chemistry. 2006; 281: 7260-7270.
    • (2006) Journal of Biological Chemistry , vol.281 , pp. 7260-7270
    • Li, J.1    Lee, B.2    Lee, A.S.3
  • 39
    • 57049117856 scopus 로고    scopus 로고
    • Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
    • Inki K, Wenjie X, John CR. Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nature Reviews Drug Discovery. 2008; 7: 1013-1030.
    • (2008) Nature Reviews Drug Discovery , vol.7 , pp. 1013-1030
    • Inki, K.1    Wenjie, X.2    John, C.R.3
  • 40
    • 84899762669 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-mediated activation of p38 MAPK, Caspase-2 and Caspase-8 leads to abrin-induced apoptosis
    • Mishra R, Karande AA. Endoplasmic reticulum stress-mediated activation of p38 MAPK, Caspase-2 and Caspase-8 leads to abrin-induced apoptosis. PLoS One. 2014; 9:e92586.
    • (2014) PLoS One , vol.9 , pp. e92586
    • Mishra, R.1    Karande, A.A.2
  • 42
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell. 2009; 139: 871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 43
    • 33745297408 scopus 로고    scopus 로고
    • New signals from the invasive front
    • Christofori G. New signals from the invasive front. Nature. 2006; 441: 444-450.
    • (2006) Nature , vol.441 , pp. 444-450
    • Christofori, G.1
  • 44
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nature Reviews Cancer. 2002; 2: 442-454.
    • (2002) Nature Reviews Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 45
    • 20744439516 scopus 로고    scopus 로고
    • The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it
    • Hay ED. The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it. Developmental Dynamics. 2005; 233:706-720.
    • (2005) Developmental Dynamics , vol.233 , pp. 706-720
    • Hay, E.D.1
  • 46
    • 84880616839 scopus 로고    scopus 로고
    • Epithelial-mesenchymal Transition and Cell Invasion
    • Son H, Moon A. Epithelial-mesenchymal Transition and Cell Invasion. Toxicology Research. 2010; 26: 245-52.
    • (2010) Toxicology Research , vol.26 , pp. 245-252
    • Son, H.1    Moon, A.2
  • 47
    • 33845787147 scopus 로고    scopus 로고
    • "Knockdown of ribosomal protein S3 protects human cells from genotoxic stress,"
    • Hegde V, Yadavilli S, Deutsch WA. "Knockdown of ribosomal protein S3 protects human cells from genotoxic stress," DNA Repair. 2007; 6 (1): 94-99.
    • (2007) DNA Repair , vol.6 , Issue.1 , pp. 94-99
    • Hegde, V.1    Yadavilli, S.2    Deutsch, W.A.3
  • 48
    • 84859739738 scopus 로고    scopus 로고
    • Akt: A Double-Edged Sword in Cell Proliferation and Genome Stability
    • 951724
    • Xu N, Lao Y, Zhang Y, Gillespie DA. Akt: A Double-Edged Sword in Cell Proliferation and Genome Stability. Journal of Oncology. 2012, 951724: 1-15.
    • (2012) Journal of Oncology , pp. 1-15
    • Xu, N.1    Lao, Y.2    Zhang, Y.3    Gillespie, D.A.4


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