|
|
Volumn 10, Issue 1, 2015, Pages 52-56
|
|
Evaluating p97 Inhibitor Analogues for Their Domain Selectivity and Potency against the p97-p47 Complex
a,c
a
a
a
b
b
a
b
a
|
|
Author keywords
AAA ATPase; Antitumor agents; P97; Proteasomes; Structure activity relationships; Ubiquitin
|
|
Indexed keywords
2 (2 AMINO 1H BENZO[D]IMIDAZOL 1 YL) N BENZYL 8 METHOXYQUINAZOLIN 4 AMINE;
2 (2H BENZO[B][1,4]OXAZIN 4(3H)YL) N BENZYL 5,6,7,8 TETRAHYDROQUINAZOLIN 4 AMINE;
ADENOSINE TRIPHOSPHATASE INHIBITOR;
MUTANT PROTEIN;
N2,N4 DIBENZYLQUINAZOLINE 2,4 DIAMINE;
NMS 873;
PROTEIN P47;
PROTEIN P97;
UNCLASSIFIED DRUG;
ADENOSINE TRIPHOSPHATASE;
ANTINEOPLASTIC AGENT;
BENZIMIDAZOLE DERIVATIVE;
BENZOXAZINE DERIVATIVE;
ENZYME INHIBITOR;
ML240 COMPOUND;
ML241 COMPOUND;
N2,N4-DIBENZYLQUINAZOLINE-2,4-DIAMINE;
NUCLEAR PROTEIN;
P37 PROTEIN, HUMAN;
P97 ATPASE;
PROTEIN BINDING;
QUINAZOLINE DERIVATIVE;
SIGNAL TRANSDUCING ADAPTOR PROTEIN;
ARTICLE;
COMPLEX FORMATION;
CONFORMATIONAL TRANSITION;
CONTROLLED STUDY;
DRUG POTENCY;
DRUG PROTEIN BINDING;
DRUG SCREENING;
DRUG SELECTIVITY;
DRUG TARGETING;
ENZYME INHIBITION;
ENZYME INHIBITION ASSAY;
HIGH THROUGHPUT SCREENING;
HUMAN;
PROTEIN DOMAIN;
STRUCTURE ACTIVITY RELATION;
WILD TYPE;
ANTAGONISTS AND INHIBITORS;
CHEMISTRY;
GENETICS;
METABOLISM;
MUTATION;
PROTEIN TERTIARY STRUCTURE;
ADAPTOR PROTEINS, SIGNAL TRANSDUCING;
ADENOSINE TRIPHOSPHATASES;
ANTINEOPLASTIC AGENTS;
BENZIMIDAZOLES;
BENZOXAZINES;
ENZYME INHIBITORS;
HUMANS;
MUTATION;
NUCLEAR PROTEINS;
PROTEIN BINDING;
PROTEIN STRUCTURE, TERTIARY;
QUINAZOLINES;
STRUCTURE-ACTIVITY RELATIONSHIP;
|
|
EID: 84919752706
PISSN: 18607179
EISSN: 18607187
Source Type: Journal
DOI: 10.1002/cmdc.201402420 Document Type: Article |
|
Times cited : (26)
|
|
References (24)
|
