-
1
-
-
85005963605
-
Pharmacological manipulation of transcription factor protein-protein interactions: Opportunities and obstacles
-
Fontaine F, Overman J, Francois M. Pharmacological manipulation of transcription factor protein-protein interactions: opportunities and obstacles. Cell regeneration (London, England). 2015;4(1):2. PubMed PMID: 25848531. Pubmed Central PMCID: PMC4365538. Epub 2015/04/08. eng.
-
(2015)
Cell Regeneration (London, England)
, vol.4
, Issue.1
-
-
Fontaine, F.1
Overman, J.2
Francois, M.3
-
2
-
-
23044496736
-
Protein-protein interactions in human disease
-
Ryan DP, Matthews JM. Protein-protein interactions in human disease. Curr Opin Struct Biol. 2005 Aug;15(4):441-6. PubMed PMID: 15993577. Epub 2005/07/05. eng.
-
(2005)
Curr Opin Struct Biol
, vol.15
, Issue.4
, pp. 441-446
-
-
Ryan, D.P.1
Matthews, J.M.2
-
3
-
-
84902786420
-
Drug-like protein-protein interaction modulators: Challenges and opportunities for drug discovery and chemical biology
-
Jun
-
Villoutreix BO, Kuenemann MA, Poyet JL, Bruzzoni-Giovanelli H, Labbe C, Lagorce D, Sperandio O, Miteva MA. Drug-like protein-protein interaction modulators: challenges and opportunities for drug discovery and chemical biology. Mol Inform. 2014 Jun;33(6–7):414–37. PubMed PMID: 25254076. Pubmed Central PMCID: PMC4160817. Epub 2014/09/26. Eng.
-
(2014)
Mol Inform
, vol.33
, Issue.6-7
, pp. 414-437
-
-
Villoutreix, B.O.1
Kuenemann, M.A.2
Poyet, J.L.3
Bruzzoni-Giovanelli, H.4
Labbe, C.5
Lagorce, D.6
Sperandio, O.7
Miteva, M.A.8
-
5
-
-
33645887230
-
Critical review of the role of HTS in drug discovery
-
Macarron R. Critical review of the role of HTS in drug discovery. Drug discovery today. 2006;11(7-8):277-9.
-
(2006)
Drug Discovery Today
, vol.11
, Issue.7-8
, pp. 277-279
-
-
Macarron, R.1
-
6
-
-
37249004920
-
Reaching for high-hanging fruit in drug discovery at protein-protein interfaces
-
Wells JA, McClendon CL. Reaching for high-hanging fruit in drug discovery at protein-protein interfaces. Nature. 2007;450(7172):1001-9.
-
(2007)
Nature
, vol.450
, Issue.7172
, pp. 1001-1009
-
-
Wells, J.A.1
McClendon, C.L.2
-
8
-
-
33847381100
-
A decade of fragment-based drug design: Strategic advances and lessons learned
-
Hajduk PJ, Greer J. A decade of fragment-based drug design: strategic advances and lessons learned. Nature reviews Drug discovery. 2007;6(3):211-9.
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.3
, pp. 211-219
-
-
Hajduk, P.J.1
Greer, J.2
-
9
-
-
33748578600
-
Targeting protein-protein interactions with small molecules: Challenges and perspectives for computational binding epitope detection and ligand finding
-
Gonzalez-Ruiz D, Gohlke H. Targeting protein-protein interactions with small molecules: challenges and perspectives for computational binding epitope detection and ligand finding. Curr Med Chem. 2006;13(22):2607–25. PubMed PMID: 17017914. Epub 2006/10/05.eng.
-
(2006)
Curr Med Chem
, vol.13
, Issue.22
, pp. 2607-2625
-
-
Gonzalez-Ruiz, D.1
Gohlke, H.2
-
10
-
-
41649102468
-
Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition
-
Mar 11
-
Shangary S, Qin D, McEachern D, Liu M, Miller RS, Qiu S, Nikolovska-Coleska Z, Ding K, Wang G, Chen J, Bernard D, Zhang J, Lu Y, Gu Q, Shah RB, Pienta KJ, Ling X, Kang S, Guo M, Sun Y, Yang D, Wang S. Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3933–8. PubMed PMID: 18316739. Pubmed Central PMCID: PMC2268798. Epub 2008/03/05. eng.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.10
, pp. 3933-3938
-
-
Shangary, S.1
Qin, D.2
McEachern, D.3
Liu, M.4
Miller, R.S.5
Qiu, S.6
Nikolovska-Coleska, Z.7
Ding, K.8
Wang, G.9
Chen, J.10
Bernard, D.11
Zhang, J.12
Lu, Y.13
Gu, Q.14
Shah, R.B.15
Pienta, K.J.16
Ling, X.17
Kang, S.18
Guo, M.19
Sun, Y.20
Yang, D.21
Wang, S.22
more..
-
11
-
-
78649275318
-
Highly specific modulators of protein kinase C localization: Applications to heart failure
-
Qvit N, Mochly-Rosen D. Highly specific modulators of protein kinase C localization: applications to heart failure. Drug Discov Today Dis Mech. 2010;7(2):e87-e93.
-
(2010)
Drug Discov Today Dis Mech
, vol.7
, Issue.2
, pp. e87-e93
-
-
Qvit, N.1
Mochly-Rosen, D.2
-
12
-
-
33846155913
-
Structure-based maximal affinity model predicts small-molecule druggability
-
Jan
-
Cheng AC, Coleman RG, Smyth KT, Cao Q, Soulard P, Caffrey DR, Salzberg AC, Huang ES. Structure-based maximal affinity model predicts small-molecule druggability. Nat Biotechnol. 2007 Jan;25(1):71–5. PubMed PMID: 17211405. Epub 2007/01/11. eng.
-
(2007)
Nat Biotechnol
, vol.25
, Issue.1
, pp. 71-75
-
-
Cheng, A.C.1
Coleman, R.G.2
Smyth, K.T.3
Cao, Q.4
Soulard, P.5
Caffrey, D.R.6
Salzberg, A.C.7
Huang, E.S.8
-
13
-
-
84891850975
-
Targeting protein-protein interaction by small molecules
-
Jin L, Wang W, Fang G. Targeting protein-protein interaction by small molecules. Annu Rev Pharmacol Toxicol. 2014;54:435–56. PubMed PMID: 24160698. Epub 2013/10/29. eng.
-
(2014)
Annu Rev Pharmacol Toxicol
, vol.54
, pp. 435-456
-
-
Jin, L.1
Wang, W.2
Fang, G.3
-
14
-
-
84920996975
-
Peptides that target protein-protein interactions as an anti-parasite strategy
-
Qvit N, Crapster JA. Peptides that target protein-protein interactions as an anti-parasite strategy. Chimica Oggi/CHEMISTRY today. 2014;32(6):62–6.
-
(2014)
Chimica Oggi/Chemistry Today
, vol.32
, Issue.6
, pp. 62-66
-
-
Qvit, N.1
Crapster, J.A.2
-
15
-
-
3142781225
-
Small-molecule inhibitors of protein-protein interactions: Progressing towards the dream
-
Apr
-
Arkin MR, Wells JA. Small-molecule inhibitors of protein-protein interactions: progressing towards the dream. Nature Revs Drug Discov. 2004 Apr;3(4):301–17. PubMed PMID: 15060526. Epub 2004/04/03. eng.
-
(2004)
Nature Revs Drug Discov
, vol.3
, Issue.4
, pp. 301-317
-
-
Arkin, M.R.1
Wells, J.A.2
-
16
-
-
62149129236
-
Therapeutic antibodies: Successes, limitations and hopes for the future
-
May
-
Chames P, Van Regenmortel M, Weiss E, Baty D. Therapeutic antibodies: successes, limitations and hopes for the future. Br J Pharmacol. 2009 May;157(2):220–33. PubMed PMID: 19459844. Pubmed Central PMCID: PMC2697811. Epub 2009/05/23. eng.
-
(2009)
Br J Pharmacol
, vol.157
, Issue.2
, pp. 220-233
-
-
Chames, P.1
Van Regenmortel, M.2
Weiss, E.3
Baty, D.4
-
17
-
-
49549083915
-
Peptide-mediated interactions in biological systems: New discoveries and applications
-
Aug
-
Petsalaki E, Russell RB. Peptide-mediated interactions in biological systems: new discoveries and applications. Curr Opin Biotechnol. 2008 Aug;19(4):344–50. PubMed PMID: 18602004. Epub 2008/07/08. eng.
-
(2008)
Curr Opin Biotechnol
, vol.19
, Issue.4
, pp. 344-350
-
-
Petsalaki, E.1
Russell, R.B.2
-
18
-
-
84858141302
-
Modeling peptide-protein interactions
-
London N, Raveh B, Schueler-Furman O. Modeling peptide-protein interactions. Methods Mol Biol. 2012;857:375–98. PubMed PMID: 22323231. Epub 2012/02/11. eng.
-
(2012)
Methods Mol Biol
, vol.857
, pp. 375-398
-
-
London, N.1
Raveh, B.2
Schueler-Furman, O.3
-
20
-
-
77953639812
-
Using peptides to study protein–protein interactions
-
Benyamini H, Friedler A. Using peptides to study protein–protein interactions. Future. 2010;2(6):989–1003.
-
(2010)
Future
, vol.2
, Issue.6
, pp. 989-1003
-
-
Benyamini, H.1
Friedler, A.2
-
21
-
-
84920958180
-
Development and therapeutic applications of oligonucleotides and peptides
-
Qvit N. Development and therapeutic applications of oligonucleotides and peptides. Chimica Oggi (Chemistry Today). 2011;29(2):4–7.
-
(2011)
Chimica Oggi (Chemistry Today)
, vol.29
, Issue.2
, pp. 4-7
-
-
Qvit, N.1
-
23
-
-
0037453510
-
Assembly of cell regulatory systems through protein interaction domains
-
Pawson T, Nash P. Assembly of cell regulatory systems through protein interaction domains. Science. 2003;300(5618):445.
-
(2003)
Science
, vol.300
, Issue.5618
-
-
Pawson, T.1
Nash, P.2
-
24
-
-
33751218547
-
Therapeutic peptides: Technological advances driving peptides into development
-
Sato AK, Viswanathan M, Kent RB, Wood CR. Therapeutic peptides: technological advances driving peptides into development. Curr Opin Biotechnol. 2006 Dec;17(6):638–42. PubMed PMID: 17049837. Epub 2006/10/20. eng.
-
(2006)
Curr Opin Biotechnol
, vol.17
, Issue.6
, pp. 638-642
-
-
Sato, A.K.1
Viswanathan, M.2
Kent, R.B.3
Wood, C.R.4
-
25
-
-
0032833799
-
Terminal modifications inhibit proteolytic degradation of an immunogenic MART-1(27–35) peptide: Implications for peptide vaccines
-
Oct 29
-
Brinckerhoff LH, Kalashnikov VV, Thompson LW, Yamshchikov GV, Pierce RA, Galavotti HS, Engelhard VH, Slingluff CL, Jr. Terminal modifications inhibit proteolytic degradation of an immunogenic MART-1(27–35) peptide: implications for peptide vaccines. Int J Cancer. 1999 Oct 29;83(3):326–34. PubMed PMID: 10495424. Epub 1999/09/25. eng.
-
(1999)
Int J Cancer
, vol.83
, Issue.3
, pp. 326-334
-
-
Brinckerhoff, L.H.1
Kalashnikov, V.V.2
Thompson, L.W.3
Yamshchikov, G.V.4
Pierce, R.A.5
Galavotti, H.S.6
Engelhard, V.H.7
Slingluff, C.L.8
-
26
-
-
0036782913
-
Peptidomimetics and peptide backbone modifications
-
Oct
-
Ahn JM, Boyle NA, MacDonald MT, Janda KD. Peptidomimetics and peptide backbone modifications. Mini Rev Med Chem. 2002 Oct;2(5):463–73. PubMed PMID: 12370047. Epub 2002/10/09. eng.
-
(2002)
Mini Rev Med Chem
, vol.2
, Issue.5
, pp. 463-473
-
-
Ahn, J.M.1
Boyle, N.A.2
Macdonald, M.T.3
Janda, K.D.4
-
27
-
-
85019505265
-
Constrained peptides as miniature protein structures
-
Yin H. Constrained peptides as miniature protein structures. ISRN Biochem. 2012;2012:1–15.
-
(2012)
ISRN Biochem
, vol.2012
, pp. 1-15
-
-
Yin, H.1
-
28
-
-
84989909744
-
Synthesis of special peptides and peptide conjugates
-
Sewald N, Jakubke H. Synthesis of special peptides and peptide conjugates. Peptide Chem Biol VCH. 2002:311–34.
-
(2002)
Peptide Chem Biol VCH
, pp. 311-334
-
-
Sewald, N.1
Jakubke, H.2
-
29
-
-
42449085846
-
Synthesis of a novel macrocyclic library: Discovery of an IGF-1R inhibitor
-
Mar–Apr
-
Qvit N, Reuveni H, Gazal S, Zundelevich A, Blum G, Niv MY, Feldstein A, Meushar S, Shalev DE, Friedler A, Gilon C. Synthesis of a novel macrocyclic library: discovery of an IGF-1R inhibitor. J Combin Chem. 2008 Mar–Apr;10(2):256–66. PubMed PMID: 18271560. Epub 2008/02/15. eng.
-
(2008)
J Combin Chem
, vol.10
, Issue.2
, pp. 256-266
-
-
Qvit, N.1
Reuveni, H.2
Gazal, S.3
Zundelevich, A.4
Blum, G.5
Niv, M.Y.6
Feldstein, A.7
Meushar, S.8
Shalev, D.E.9
Friedler, A.10
Gilon, C.11
-
30
-
-
59949087980
-
Design and synthesis of backbone cyclic phosphorylated peptides: The IκB model
-
Qvit N, Hatzubai A, Shalev DE, Friedler A, Ben-Neriah Y, Gilon C. Design and synthesis of backbone cyclic phosphorylated peptides: the IκB model. Biopolymers. 2009;91(2):157–68.
-
(2009)
Biopolymers
, vol.91
, Issue.2
, pp. 157-168
-
-
Qvit, N.1
Hatzubai, A.2
Shalev, D.E.3
Friedler, A.4
Ben-Neriah, Y.5
Gilon, C.6
-
31
-
-
84922969038
-
Microwave-assisted synthesis of cyclic phosphopeptide on solid support
-
Qvit N. Microwave-assisted synthesis of cyclic phosphopeptide on solid support. Chem Biol Drug Des. 2014;85(3):300–5.
-
(2014)
Chem Biol Drug Des
, vol.85
, Issue.3
, pp. 300-305
-
-
Qvit, N.1
-
32
-
-
0035289779
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
Lipinski CA, Lombardo F, Dominy BW, Feeney PJ. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev. 2001 Mar 1;46(1–3):3–26. PubMed PMID: 11259830.
-
(2001)
Adv Drug Deliv Rev
, vol.46
, Issue.1-3
, pp. 3-26
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
33
-
-
0037030653
-
Molecular properties that influence the oral bioavailability of drug candidates
-
Jun 6
-
Veber DF, Johnson SR, Cheng HY, Smith BR, Ward KW, Kopple KD. Molecular properties that influence the oral bioavailability of drug candidates. J Med Chem. 2002 Jun 6;45(12):2615–23. PubMed PMID: 12036371.
-
(2002)
J Med Chem
, vol.45
, Issue.12
, pp. 2615-2623
-
-
Veber, D.F.1
Johnson, S.R.2
Cheng, H.Y.3
Smith, B.R.4
Ward, K.W.5
Kopple, K.D.6
-
34
-
-
84864745214
-
Cyclosporine: A review
-
Tedesco D, Haragsim L. Cyclosporine: a review. J Transplant. 2012;2012:230386. doi: 10.1155/2012/230386.
-
(2012)
J Transplant
, vol.2012
-
-
Tedesco, D.1
Haragsim, L.2
-
36
-
-
0345097576
-
Learning from nature’s drug factories: Nonribosomal synthesis of macrocyclic peptides
-
Sieber SA, Marahiel MA. Learning from nature’s drug factories: nonribosomal synthesis of macrocyclic peptides. J Bacteriol. 2003 Dec;185(24):7036–43. PubMed PMID: 14645262. Pubmed Central PMCID: PMC296262. Epub 2003/12/04. eng.
-
(2003)
J Bacteriol
, vol.185
, Issue.24
, pp. 7036-7043
-
-
Sieber, S.A.1
Marahiel, M.A.2
-
37
-
-
84857147068
-
Cyclic peptides as therapeutic agents and biochemical tools
-
Joo SH. Cyclic peptides as therapeutic agents and biochemical tools. Biomol Ther (Seoul). 2012 Jan;20(1):19–26. PubMed PMID: 24116270. Pubmed Central PMCID: PMC3792197. Epub 2012/01/01. Eng.
-
(2012)
Biomol Ther (Seoul)
, vol.20
, Issue.1
, pp. 19-26
-
-
Joo, S.H.1
-
38
-
-
0346328229
-
Opportunities in somatostatin research: Biological, chemical and therapeutic aspects
-
Weckbecker G, Lewis I, Albert R, Schmid HA, Hoyer D, Bruns C. Opportunities in somatostatin research: biological, chemical and therapeutic aspects. Nature Revs Drug Discov. 2003 Dec;2(12):999–1017. PubMed PMID: 14654798. Epub 2003/12/05. eng.
-
(2003)
Nature Revs Drug Discov
, vol.2
, Issue.12
, pp. 999-1017
-
-
Weckbecker, G.1
Lewis, I.2
Albert, R.3
Schmid, H.A.4
Hoyer, D.5
Bruns, C.6
-
39
-
-
84933677744
-
Therapeutic uses of somatostatin and its analogues: Current view and potential applications
-
Aug
-
Rai U, Thrimawithana TR, Valery C, Young SA. Therapeutic uses of somatostatin and its analogues: Current view and potential applications. Pharmacol Ther. 2015 Aug;152:98–110. PubMed PMID: 25956467. Epub 2015/05/10. eng.
-
(2015)
Pharmacol Ther
, vol.152
, pp. 98-110
-
-
Rai, U.1
Thrimawithana, T.R.2
Valery, C.3
Young, S.A.4
-
40
-
-
84921442644
-
Peptide therapeutics: Current status and future directions
-
Fosgerau K, Hoffmann T. Peptide therapeutics: Current status and future directions. Drug discovery today. 2015;20(1):122-8.
-
(2015)
Drug Discovery Today
, vol.20
, Issue.1
, pp. 122-128
-
-
Fosgerau, K.1
Hoffmann, T.2
-
41
-
-
0034141430
-
In vivo protein transduction: Intracellular delivery of biologically active proteins, compounds and DNA
-
Schwarze SR, Dowdy SF. In vivo protein transduction: intracellular delivery of biologically active proteins, compounds and DNA. Trends Pharmacol Sci. 2000 Feb;21(2):45–8. PubMed PMID: 10664605. Epub 2000/02/09. eng.
-
(2000)
Trends Pharmacol Sci
, vol.21
, Issue.2
, pp. 45-48
-
-
Schwarze, S.R.1
Dowdy, S.F.2
-
42
-
-
79955595804
-
Cyclosporin A—a review on fermentative production, downstream processing and pharmacological applications
-
7
-
Survase SA, Kagliwal LD, Annapure US, Singhal RS. Cyclosporin A—a review on fermentative production, downstream processing and pharmacological applications. Biotechnology advances. 2011 7//;29(4):418–35.
-
(2011)
Biotechnology Advances
, vol.29
, Issue.4
, pp. 418-435
-
-
Survase, S.A.1
Kagliwal, L.D.2
Annapure, U.S.3
Singhal, R.S.4
-
43
-
-
0004274772
-
Chemistry of cyclosporine
-
DJG White (Ed.), Elsevier Biomedical Press, Amsterdam
-
Wenger, R. Chemistry of cyclosporine. in: DJG White (Ed.) Cyclosporin A. Elsevier Biomedical Press, Amsterdam; 1982:19–34.
-
(1982)
Cyclosporin A
, pp. 19-34
-
-
Wenger, R.1
-
44
-
-
0017089709
-
Cyclosporin A and C new metabolites from Trichoderma polysporum (Link ex Dreyfuss M, Harri E, Hofmann H, Kobel H, Pache W, Tscherter H. Cyclosporin A and C new metabolites from Trichoderma polysporum
-
Dreyfuss M, Harri E, Hofmann H, Kobel H, Pache W, Tscherter H. Cyclosporin A and C new metabolites from Trichoderma polysporum (Link expers.) Rifai Eur J Appl Microbiol. 1976;3(2):125–33. PubMed PMID: WOS:A1976CN82600006. English.
-
(1976)
(Link Ex Pers.) Rifai Eur J Appl Microbiol
, vol.3
, Issue.2
, pp. 125-133
-
-
Dreyfuss, M.1
Harri, E.2
Hofmann, H.3
Kobel, H.4
Pache, W.5
Tscherter, H.6
-
45
-
-
0017157814
-
Biological effects of cyclosporin A: A new antilymphocytic agent
-
Jul
-
Borel JF, Feurer C, Gubler HU, Stahelin H. Biological effects of cyclosporin A: a new antilymphocytic agent. Agents Actions. 1976 Jul;6(4):468–75. PubMed PMID: 8969. Epub 1976/07/01. eng.
-
(1976)
Agents Actions
, vol.6
, Issue.4
, pp. 468-475
-
-
Borel, J.F.1
Feurer, C.2
Gubler, H.U.3
Stahelin, H.4
-
46
-
-
0021341035
-
Synthesis of cyclosporine. Total syntheses of ‘cyclosporin A’ and ‘cyclosporin H’, two fungal metabolites isolated from the species Tolypocladium inflatum GAMS
-
Wenger RM. Synthesis of cyclosporine. Total syntheses of ‘cyclosporin A’ and ‘cyclosporin H’, two fungal metabolites isolated from the species Tolypocladium inflatum GAMS. Helv Chim Acta. 1984;67(2):502–25.
-
(1984)
Helv Chim Acta
, vol.67
, Issue.2
, pp. 502-525
-
-
Wenger, R.M.1
-
47
-
-
0034045947
-
Mechanisms of action of cyclosporine
-
May
-
Matsuda S, Koyasu S. Mechanisms of action of cyclosporine. Immunopharmacology. 2000 May;47(2–3):119–25. PubMed PMID: 10878286. Epub 2000/07/06. eng.
-
(2000)
Immunopharmacology
, vol.47
, Issue.2-3
, pp. 119-125
-
-
Matsuda, S.1
Koyasu, S.2
-
48
-
-
84922735582
-
Safety and Efficacy of Cyclosporine in the Treatment of Chronic Dry Eye
-
Schultz C. Safety and Efficacy of Cyclosporine in the Treatment of Chronic Dry Eye. Ophthalmol Eye Dis. 2014 06/24, 04/10/received, 05/07/ revised, 05/12/accepted;6:37-42. PubMed PMID: PMC4076204.
-
(2014)
Ophthalmol Eye Dis
-
-
Schultz, C.1
-
49
-
-
84864745214
-
Cyclosporine: A review
-
Tedesco D, Haragsim L. Cyclosporine: a review. J Transplant. 2012;2012:230386. PubMed PMID: 22263104. Pubmed Central PMCID: PMC3259474. Epub 2012/01/21. eng.
-
(2012)
J Transplant
, vol.2012
-
-
Tedesco, D.1
Haragsim, L.2
-
50
-
-
85025407868
-
The production of bactericidal substances by aerobic sporulating bacilli
-
Apr 30
-
Dubos RJ, Hotchkiss RD. The production of bactericidal substances by aerobic sporulating bacilli. J Exp Med. 1941 Apr 30;73(5):629–40. PubMed PMID: 19871101. Pubmed Central PMCID: PMC2135154. Epub 1941/04/30. eng.
-
(1941)
J Exp Med
, vol.73
, Issue.5
, pp. 629-640
-
-
Dubos, R.J.1
Hotchkiss, R.D.2
-
51
-
-
0001131165
-
Gramicidin S and its use in the treatment of infected wounds
-
Gause G, Brazhnikova M. Gramicidin S and its use in the treatment of infected wounds. Nature. 1944;154:703.
-
(1944)
Nature
, vol.154
-
-
Gause, G.1
Brazhnikova, M.2
-
52
-
-
34548538972
-
Development of Tyrocidine A analogues with improved antibacterial activity
-
Nov 1
-
Marques MA, Citron DM, Wang CC. Development of Tyrocidine A analogues with improved antibacterial activity. Bioorg Med Chem. 2007 Nov 1;15(21):6667–77. PubMed PMID: 17728134. Pubmed Central PMCID: PMC2706120. Epub 2007/08/31. eng.
-
(2007)
Bioorg Med Chem
, vol.15
, Issue.21
, pp. 6667-6677
-
-
Marques, M.A.1
Citron, D.M.2
Wang, C.C.3
-
53
-
-
84894566211
-
The high resolution structure of tyrocidine A reveals an amphipathic dimer
-
Loll PJ, Upton EC, Nahoum V, Economou NJ, Cocklin S. The high resolution structure of tyrocidine A reveals an amphipathic dimer. Biochimica et Biophysica Acta (BBA) -Biomembranes. 2014;1838(5):1199–207.
-
(2014)
Biochimica Et Biophysica Acta (BBA) -Biomembranes
, vol.1838
, Issue.5
, pp. 1199-1207
-
-
Loll, P.J.1
Upton, E.C.2
Nahoum, V.3
Economou, N.J.4
Cocklin, S.5
-
54
-
-
19644376403
-
A novel active analogue of gramicidin S with smaller ring size
-
04//print
-
Tamaki M, Ishii R, Kikuchi S, Watanabe E. A novel active analogue of gramicidin S with smaller ring size. J Antibiot. 2005 04//print;58(4):293–5.
-
(2005)
J Antibiot
, vol.58
, Issue.4
, pp. 293-295
-
-
Tamaki, M.1
Ishii, R.2
Kikuchi, S.3
Watanabe, E.4
-
55
-
-
70849102756
-
Gramicidin S and polymyxins: The revival of cationic cyclic peptide antibiotics
-
Dec
-
Mogi T, Kita K. Gramicidin S and polymyxins: the revival of cationic cyclic peptide antibiotics. Cell Mol Life Sci. 2009 Dec;66(23):3821–6. PubMed PMID: 19701717. Epub 2009/08/25. eng.
-
(2009)
Cell Mol Life Sci
, vol.66
, Issue.23
, pp. 3821-3826
-
-
Mogi, T.1
Kita, K.2
-
56
-
-
0015914428
-
Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone
-
Jan 5
-
Brazeau P, Vale W, Burgus R, Ling N, Butcher M, Rivier J, Guillemin R. Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone. Science. 1973 Jan 5;179(4068):77–9. PubMed PMID: 4682131. Epub 1973/01/05. eng.
-
(1973)
Science
, vol.179
, Issue.4068
, pp. 77-79
-
-
Brazeau, P.1
Vale, W.2
Burgus, R.3
Ling, N.4
Butcher, M.5
Rivier, J.6
Guillemin, R.7
-
57
-
-
84883251306
-
Somatostatin replacement: A new strategy for treating diabetic retino-pathy
-
Hernandez C, Simo R. Somatostatin replacement: a new strategy for treating diabetic retino-pathy. Curr Med Chem. 2013;20(26):3251–7. PubMed PMID: 23745546. Epub 2013/06/12. eng.
-
(2013)
Curr Med Chem
, vol.20
, Issue.26
, pp. 3251-3257
-
-
Hernandez, C.1
Simo, R.2
-
58
-
-
84902316929
-
Somatostatin and diabetic retinopathy: Current concepts and new therapeutic perspectives
-
Jun
-
Hernandez C, Simo-Servat O, Simo R. Somatostatin and diabetic retinopathy: current concepts and new therapeutic perspectives. Endocrine. 2014 Jun;46(2):209–14. PubMed PMID: 24627166. Epub 2014/03/15. eng.
-
(2014)
Endocrine
, vol.46
, Issue.2
, pp. 209-214
-
-
Hernandez, C.1
Simo-Servat, O.2
Simo, R.3
-
59
-
-
84955127163
-
Role of Somatostatin Analogues in the Treatment of Neuroendocrine Tumors
-
Feb
-
Narayanan S, Kunz PL. Role of Somatostatin Analogues in the Treatment of Neuroendocrine Tumors. Hematol Oncol Clin North Am. 2016 Feb;30(1):163–77. PubMed PMID: 26614375. Epub 2015/11/29. eng.
-
(2016)
Hematol Oncol Clin North Am
, vol.30
, Issue.1
, pp. 163-177
-
-
Narayanan, S.1
Kunz, P.L.2
-
60
-
-
79955067473
-
Somatostatin analogues for treatment of polycystic liver disease
-
May
-
Gevers TJ, Drenth JP. Somatostatin analogues for treatment of polycystic liver disease. Current opinion in gastroenterology. 2011 May;27(3):294–300. PubMed PMID: 21191289. Epub 2010/12/31. eng.
-
(2011)
Current Opinion in Gastroenterology
, vol.27
, Issue.3
, pp. 294-300
-
-
Gevers, T.J.1
Drenth, J.P.2
-
61
-
-
80052656818
-
Systematic review and meta-analysis of the role of somatostatin and its analogues in the treatment of enterocutaneous fistula
-
Oct
-
Stevens P, Foulkes RE, Hartford-Beynon JS, Delicata RJ. Systematic review and meta-analysis of the role of somatostatin and its analogues in the treatment of enterocutaneous fistula. Eur J Gastroenterol Hepatol. 2011 Oct;23(10):912–22. PubMed PMID: 21814141. Epub 2011/08/05. eng.
-
(2011)
Eur J Gastroenterol Hepatol
, vol.23
, Issue.10
, pp. 912-922
-
-
Stevens, P.1
Foulkes, R.E.2
Hartford-Beynon, J.S.3
Delicata, R.J.4
-
63
-
-
0141740217
-
The therapeutic potential of somatostatin receptor ligands in the treatment of obesity and diabetes
-
Sep
-
Boehm BO. The therapeutic potential of somatostatin receptor ligands in the treatment of obesity and diabetes. Expert opinion on investigational drugs. 2003 Sep;12(9):1501–9. PubMed PMID: 12943494. Epub 2003/08/29. eng.
-
(2003)
Expert Opinion on Investigational Drugs
, vol.12
, Issue.9
, pp. 1501-1509
-
-
Boehm, B.O.1
-
64
-
-
72549097292
-
From somatostatin to octreotide LAR: Evolution of a somatostatin analogue
-
Dec
-
Anthony L, Freda PU. From somatostatin to octreotide LAR: evolution of a somatostatin analogue. Curr Med Res Opin. 2009 Dec;25(12):2989–99. PubMed PMID: 19842996. Pubmed Central PMCID: PMC3678951. Epub 2009/10/22. eng.
-
(2009)
Curr Med Res Opin
, vol.25
, Issue.12
, pp. 2989-2999
-
-
Anthony, L.1
Freda, P.U.2
-
65
-
-
43549109282
-
Somatostatin agonists for treatment of acromegaly
-
11/29
-
Ben-Shlomo A, Melmed S. Somatostatin agonists for treatment of acromegaly. Mol Cell Endocrinol. 2008 11/29;286(1–2):192–8. PubMed PMID: PMC2697610.
-
(2008)
Mol Cell Endocrinol
, vol.286
, Issue.1-2
, pp. 192-198
-
-
Ben-Shlomo, A.1
Melmed, S.2
-
66
-
-
9244222261
-
Targeted cancer therapy
-
Nov 18
-
Sawyers C. Targeted cancer therapy. Nature. 2004 Nov 18;432(7015):294–7. PubMed PMID: 15549090. Epub 2004/11/19. eng.
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 294-297
-
-
Sawyers, C.1
-
68
-
-
20344385260
-
Targeting apoptosis pathways in cancer therapy
-
May–Jun
-
Ghobrial IM, Witzig TE, Adjei AA. Targeting apoptosis pathways in cancer therapy. CA Cancer J Clin. 2005 May–Jun;55(3):178–94. PubMed PMID: 15890640. Epub 2005/05/14. eng.
-
(2005)
CA Cancer J Clin
, vol.55
, Issue.3
, pp. 178-194
-
-
Ghobrial, I.M.1
Witzig, T.E.2
Adjei, A.A.3
-
69
-
-
84876074186
-
Targeting apoptosis pathways by natural compounds in cancer: Marine compounds as lead structures and chemical tools for cancer therapy
-
May 28
-
von Schwarzenberg K, Vollmar AM. Targeting apoptosis pathways by natural compounds in cancer: marine compounds as lead structures and chemical tools for cancer therapy. Cancer Lett. 2013 May 28;332(2):295–303. PubMed PMID: 20673697. Epub 2010/08/03. eng.
-
(2013)
Cancer Lett
, vol.332
, Issue.2
, pp. 295-303
-
-
Von Schwarzenberg, K.1
Vollmar, A.M.2
-
70
-
-
0036247821
-
P53-Mdm2-the affair that never ends
-
Apr
-
Alarcon-Vargas D, Ronai Z. p53-Mdm2-the affair that never ends. Carcinogenesis. 2002 Apr;23(4):541–7. PubMed PMID: 11960904. Epub 2002/04/19. eng.
-
(2002)
Carcinogenesis
, vol.23
, Issue.4
, pp. 541-547
-
-
Alarcon-Vargas, D.1
Ronai, Z.2
-
71
-
-
0346455771
-
The MDM2-p53 interaction
-
Dec
-
Moll UM, Petrenko O. The MDM2-p53 interaction. Mol Cancer Res. 2003 Dec;1(14):1001–8. PubMed PMID: 14707283. Epub 2004/01/07. eng.
-
(2003)
Mol Cancer Res
, vol.1
, Issue.14
, pp. 1001-1008
-
-
Moll, U.M.1
Petrenko, O.2
-
72
-
-
53049108040
-
Targeting the MDM2-p53 interaction for cancer therapy
-
Sep 1
-
Shangary S, Wang S. Targeting the MDM2-p53 interaction for cancer therapy. Clin Cancer Res. 2008 Sep 1;14(17):5318–24. PubMed PMID: 18765522. Pubmed Central PMCID: PMC2676446. Epub 2008/09/04. eng.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.17
, pp. 5318-5324
-
-
Shangary, S.1
Wang, S.2
-
73
-
-
84893274453
-
Targeting MDM2-p53 interaction for cancer therapy: Are we there yet?
-
Nag S, Zhang X, Srivenugopal KS, Wang MH, Wang W, Zhang R. Targeting MDM2-p53 interaction for cancer therapy: are we there yet? Curr Med Chem. 2014;21(5):553–74. PubMed PMID: 24180275. Epub 2013/11/05. eng.
-
(2014)
Curr Med Chem
, vol.21
, Issue.5
, pp. 553-574
-
-
Nag, S.1
Zhang, X.2
Srivenugopal, K.S.3
Wang, M.H.4
Wang, W.5
Zhang, R.6
-
74
-
-
0035977612
-
Isolation and structure elucidation of Chlorofusin, a novel p53-MDM2 antagonist from a Fusarium sp
-
Jan 31
-
Duncan SJ, Gruschow S, Williams DH, McNicholas C, Purewal R, Hajek M, Gerlitz M, Martin S, Wrigley SK, Moore M. Isolation and structure elucidation of Chlorofusin, a novel p53-MDM2 antagonist from a Fusarium sp. J Am Chem Soc. 2001 Jan 31;123(4):554–60. PubMed PMID: 11456567. Epub 2001/07/18. eng.
-
(2001)
J am Chem Soc
, vol.123
, Issue.4
, pp. 554-560
-
-
Duncan, S.J.1
Gruschow, S.2
Williams, D.H.3
McNicholas, C.4
Purewal, R.5
Hajek, M.6
Gerlitz, M.7
Martin, S.8
Wrigley, S.K.9
Moore, M.10
-
76
-
-
4544342753
-
Using a beta-hairpin to mimic an alpha-helix: Cyclic peptidomimetic inhibitors of the p53-HDM2 protein-protein interaction
-
Apr 13
-
Fasan R, Dias RL, Moehle K, Zerbe O, Vrijbloed JW, Obrecht D, Robinson JA. Using a beta-hairpin to mimic an alpha-helix: cyclic peptidomimetic inhibitors of the p53-HDM2 protein-protein interaction. Angew Chem Int Ed Engl. 2004 Apr 13;43(16):2109–12. PubMed PMID: 15083458. Epub 2004/04/15. eng.
-
(2004)
Angew Chem Int Ed Engl
, vol.43
, Issue.16
, pp. 2109-2112
-
-
Fasan, R.1
Dias, R.L.2
Moehle, K.3
Zerbe, O.4
Vrijbloed, J.W.5
Obrecht, D.6
Robinson, J.A.7
-
77
-
-
84944148784
-
Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin
-
Nov 1
-
Cominetti MM, Goffin SA, Raffel E, Turner KD, Ramoutar JC, O’Connell MA, Howell LA, Searcey M. Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4878–80. PubMed PMID: 26115576. Epub 2015/06/28. eng.
-
(2015)
Bioorg Med Chem Lett
, vol.25
, Issue.21
, pp. 4878-4880
-
-
Cominetti, M.M.1
Goffin, S.A.2
Raffel, E.3
Turner, K.D.4
Ramoutar, J.C.5
O’Connell, M.A.6
Howell, L.A.7
Searcey, M.8
-
78
-
-
84883432191
-
Stapled alpha-helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy
-
Aug 14
-
Chang YS, Graves B, Guerlavais V, Tovar C, Packman K, To KH, Olson KA, Kesavan K, Gangurde P, Mukherjee A, Baker T, Darlak K, Elkin C, Filipovic Z, Qureshi FZ, Cai H, Berry P, Feyfant E, Shi XE, Horstick J, Annis DA, Manning AM, Fotouhi N, Nash H, Vassilev LT, Sawyer TK. Stapled alpha-helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy. Proc Natl Acad Sci U S A. 2013 Aug 14;110(36):E3445-54. PubMed PMID: 23946421. Epub 2013/08/16. Eng.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.36
, pp. E3445-E3454
-
-
Chang, Y.S.1
Graves, B.2
Guerlavais, V.3
Tovar, C.4
Packman, K.5
To, K.H.6
Olson, K.A.7
Kesavan, K.8
Gangurde, P.9
Mukherjee, A.10
Baker, T.11
Darlak, K.12
Elkin, C.13
Filipovic, Z.14
Qureshi, F.Z.15
Cai, H.16
Berry, P.17
Feyfant, E.18
Shi, X.E.19
Horstick, J.20
Annis, D.A.21
Manning, A.M.22
Fotouhi, N.23
Nash, H.24
Vassilev, L.T.25
Sawyer, T.K.26
more..
-
79
-
-
33645469420
-
Peptide, peptidomimetic, and small-molecule antagonists of the p53–HDM2 protein–protein interaction
-
Fischer PM. Peptide, peptidomimetic, and small-molecule antagonists of the p53–HDM2 protein–protein interaction. Int J Pept Res Ther. 2006;12(1):3–19.
-
(2006)
Int J Pept Res Ther
, vol.12
, Issue.1
, pp. 3-19
-
-
Fischer, P.M.1
-
80
-
-
35348909670
-
Rational design, structure, and biological evaluation of cyclic peptides mimicking the vascular endothelial growth factor
-
Oct 18
-
Goncalves V, Gautier B, Coric P, Bouaziz S, Lenoir C, Garbay C, Vidal M, Inguimbert N. Rational design, structure, and biological evaluation of cyclic peptides mimicking the vascular endothelial growth factor. J Med Chem. 2007 Oct 18;50(21):5135–46. PubMed PMID: 17900101. Epub 2007/09/29. eng.
-
(2007)
J Med Chem
, vol.50
, Issue.21
, pp. 5135-5146
-
-
Goncalves, V.1
Gautier, B.2
Coric, P.3
Bouaziz, S.4
Lenoir, C.5
Garbay, C.6
Vidal, M.7
Inguimbert, N.8
-
81
-
-
84907494555
-
Design and synthesis of C-terminal modified cyclic peptides as VEGFR1 antagonists
-
Wang L, Gagey-Eilstein N, Broussy S, Reille-Seroussi M, Huguenot F, Vidal M, Liu WQ. Design and synthesis of C-terminal modified cyclic peptides as VEGFR1 antagonists. Molecules (Basel, Switzerland). 2014;19(10):15391–407. PubMed PMID: 25264829. Epub 2014/09/30. eng.
-
(2014)
Molecules (Basel, Switzerland)
, vol.19
, Issue.10
, pp. 15391-15407
-
-
Wang, L.1
Gagey-Eilstein, N.2
Broussy, S.3
Reille-Seroussi, M.4
Huguenot, F.5
Vidal, M.6
Liu, W.Q.7
-
82
-
-
85029552200
-
Inhibition of VEGF/VEGFR1 interaction by a series of C-terminal modified cyclic peptides
-
Wang L, Wang-Qing L, Broussy S, Gagey-Eilstein N, Reille-Seroussi M, Huguenot F, Vidal M. Inhibition of VEGF/VEGFR1 interaction by a series of C-terminal modified cyclic peptides. Receptors & Clinical Investigation. 2015;2(1):e534.
-
(2015)
Receptors & Clinical Investigation
, vol.2
, Issue.1
-
-
Wang, L.1
Wang-Qing, L.2
Broussy, S.3
Gagey-Eilstein, N.4
Reille-Seroussi, M.5
Huguenot, F.6
Vidal, M.7
-
83
-
-
47249105234
-
Structure-based design of a bicyclic peptide antagonist of the vascular endothelial growth factor receptors
-
Jun
-
Goncalves V, Gautier B, Garbay C, Vidal M, Inguimbert N. Structure-based design of a bicyclic peptide antagonist of the vascular endothelial growth factor receptors. Journal of peptide science: an official publication of the European Peptide Society. 2008 Jun;14(6):767–72. PubMed PMID: 18044812. Epub 2007/11/30. eng.
-
(2008)
Journal of Peptide Science: An Official Publication of the European Peptide Society
, vol.14
, Issue.6
, pp. 767-772
-
-
Goncalves, V.1
Gautier, B.2
Garbay, C.3
Vidal, M.4
Inguimbert, N.5
-
84
-
-
33144459287
-
VEGFR-1 and VEGFR-2: Two non-identical twins with a unique physiognomy
-
Rahimi N. VEGFR-1 and VEGFR-2: two non-identical twins with a unique physiognomy. Frontiers in bioscience: a journal and virtual library. 2006 01/01;11:818–29. PubMed PMID: PMC1360224.
-
(2006)
Frontiers in Bioscience: A Journal and Virtual Library
, vol.11
, pp. 818-829
-
-
Rahimi, N.1
-
85
-
-
79953869885
-
Engineered conformation-dependent VEGF peptide mimics are effective in inhibiting VEGF signaling pathways
-
Apr 15
-
Vicari D, Foy KC, Liotta EM, Kaumaya PT. Engineered conformation-dependent VEGF peptide mimics are effective in inhibiting VEGF signaling pathways. J Biol Chem. 2011 Apr 15;286(15):13612–25. PubMed PMID: 21321115. Pubmed Central PMCID: PMC3075706. Epub 2011/02/16. eng.
-
(2011)
J Biol Chem
, vol.286
, Issue.15
, pp. 13612-13625
-
-
Vicari, D.1
Foy, K.C.2
Liotta, E.M.3
Kaumaya, P.T.4
-
86
-
-
0042817965
-
Structure and inhibitory effects on angiogenesis and tumor development of a new vascular endothelial growth inhibitor
-
Sep 12
-
Zilberberg L, Shinkaruk S, Lequin O, Rousseau B, Hagedorn M, Costa F, Caronzolo D, Balke M, Canron X, Convert O, Lain G, Gionnet K, Goncalves M, Bayle M, Bello L, Chassaing G, Deleris G, Bikfalvi A. Structure and inhibitory effects on angiogenesis and tumor development of a new vascular endothelial growth inhibitor. J Biol Chem. 2003 Sep 12;278(37):35564–73. PubMed PMID: 12837752. Epub 2003/07/03. eng.
-
(2003)
J Biol Chem
, vol.278
, Issue.37
, pp. 35564-35573
-
-
Zilberberg, L.1
Shinkaruk, S.2
Lequin, O.3
Rousseau, B.4
Hagedorn, M.5
Costa, F.6
Caronzolo, D.7
Balke, M.8
Canron, X.9
Convert, O.10
Lain, G.11
Gionnet, K.12
Goncalves, M.13
Bayle, M.14
Bello, L.15
Chassaing, G.16
Deleris, G.17
Bikfalvi, A.18
-
87
-
-
84908408878
-
Development of a high-throughput screening-compatible assay to identify inhibitors of the CK2alpha/CK2beta interaction
-
Sep 16
-
Hochscherf J, Lindenblatt D, Steinkruger M, Yoo E, Ulucan O, Herzig S, Issinger OG, Helms V, Gotz C, Neundorf I, Niefind K, Pietsch M. Development of a high-throughput screening-compatible assay to identify inhibitors of the CK2alpha/CK2beta interaction. Anal Biochem. 2014 Sep 16;468C:4-14. PubMed PMID: 25233003. Epub 2014/09/19. Eng.
-
(2014)
Anal Biochem
, vol.468C
, pp. 4-14
-
-
Hochscherf, J.1
Lindenblatt, D.2
Steinkruger, M.3
Yoo, E.4
Ulucan, O.5
Herzig, S.6
Issinger, O.G.7
Helms, V.8
Gotz, C.9
Neundorf, I.10
Niefind, K.11
Pietsch, M.12
-
88
-
-
84944600101
-
Polo-like kinase and its inhibitors: Ready for the match to start?
-
Nov
-
Palmisiano ND, Kasner MT. Polo-like kinase and its inhibitors: Ready for the match to start? Am J Hematol. 2015 Nov;90(11):1071–6. PubMed PMID: 26294255. Epub 2015/08/22. eng.
-
(2015)
Am J Hematol
, vol.90
, Issue.11
, pp. 1071-1076
-
-
Palmisiano, N.D.1
Kasner, M.T.2
-
89
-
-
84930745615
-
Targeting Polo-Like Kinases: A Promising Therapeutic Approach for Cancer Treatment
-
Jun
-
Liu X. Targeting Polo-Like Kinases: A Promising Therapeutic Approach for Cancer Treatment. Transl Oncol. 2015 Jun;8(3):185–95. PubMed PMID: 26055176. Pubmed Central PMCID: PMC4486469. Epub 2015/06/10. eng.
-
(2015)
Transl Oncol
, vol.8
, Issue.3
, pp. 185-195
-
-
Liu, X.1
-
90
-
-
84947224577
-
PLK-1 Targeted Inhibitors and Their Potential against Tumorigenesis
-
Kumar S, Kim J. PLK-1 Targeted Inhibitors and Their Potential against Tumorigenesis. BioMed research international. 2015;2015:705745. PubMed PMID: 26557691. Pubmed Central PMCID: PMC4628734. Epub 2015/11/12. eng.
-
(2015)
Biomed Research International
, vol.2015
-
-
Kumar, S.1
Kim, J.2
-
91
-
-
84876113037
-
Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1
-
May 1
-
Murugan RN, Park JE, Lim D, Ahn M, Cheong C, Kwon T, Nam KY, Choi SH, Kim BY, Yoon DY, Yaffe MB, Yu DY, Lee KS, Bang JK. Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1. Bioorg Med Chem. 2013 May 1;21(9):2623–34. PubMed PMID: 23498919. Epub 2013/03/19. eng.
-
(2013)
Bioorg Med Chem
, vol.21
, Issue.9
, pp. 2623-2634
-
-
Murugan, R.N.1
Park, J.E.2
Lim, D.3
Ahn, M.4
Cheong, C.5
Kwon, T.6
Nam, K.Y.7
Choi, S.H.8
Kim, B.Y.9
Yoon, D.Y.10
Yaffe, M.B.11
Yu, D.Y.12
Lee, K.S.13
Bang, J.K.14
-
92
-
-
0032549531
-
Enhancement of estrogen receptor transcriptional activity by the coactivator GRIP-1 highlights the role of activation function 2 in determining estrogen receptor pharmacology
-
Mar 20
-
Norris JD, Fan D, Stallcup MR, McDonnell DP. Enhancement of estrogen receptor transcriptional activity by the coactivator GRIP-1 highlights the role of activation function 2 in determining estrogen receptor pharmacology. J Biol Chem. 1998 Mar 20;273(12):6679–88. PubMed PMID: 9506965. Epub 1998/04/18. eng.
-
(1998)
J Biol Chem
, vol.273
, Issue.12
, pp. 6679-6688
-
-
Norris, J.D.1
Fan, D.2
Stallcup, M.R.3
McDonnell, D.P.4
-
93
-
-
0033618510
-
Peptide antagonists of the human estrogen receptor
-
Jul 30
-
Norris JD, Paige LA, Christensen DJ, Chang CY, Huacani MR, Fan D, Hamilton PT, Fowlkes DM, McDonnell DP. Peptide antagonists of the human estrogen receptor. Science. 1999 Jul 30;285(5428):744–6. PubMed PMID: 10426998. Epub 1999/07/31. eng.
-
(1999)
Science
, vol.285
, Issue.5428
, pp. 744-746
-
-
Norris, J.D.1
Paige, L.A.2
Christensen, D.J.3
Chang, C.Y.4
Huacani, M.R.5
Fan, D.6
Hamilton, P.T.7
Fowlkes, D.M.8
McDonnell, D.P.9
-
94
-
-
0141706365
-
Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions
-
Sep 30
-
Leduc AM, Trent JO, Wittliff JL, Bramlett KS, Briggs SL, Chirgadze NY, Wang Y, Burris TP, Spatola AF. Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11273–8. PubMed PMID: 13679575. Pubmed Central PMCID: PMC208747. Epub 2003/09/19. eng.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.20
, pp. 11273-11278
-
-
Leduc, A.M.1
Trent, J.O.2
Wittliff, J.L.3
Bramlett, K.S.4
Briggs, S.L.5
Chirgadze, N.Y.6
Wang, Y.7
Burris, T.P.8
Spatola, A.F.9
-
95
-
-
84907525042
-
Structure-based design and synthesis of potent cyclic peptides inhibiting the YAP-TEAD protein-protein interaction
-
Sep 11
-
Zhang Z, Lin Z, Zhou Z, Shen HC, Yan SF, Mayweg AV, Xu Z, Qin N, Wong JC, Zhang Z, Rong Y, Fry DC, Hu T. Structure-based design and synthesis of potent cyclic peptides inhibiting the YAP-TEAD protein-protein interaction. ACS Med Chem Lett. 2014 Sep 11;5(9):993–8. PubMed PMID: 25221655. Pubmed Central PMCID: PMC4160762. Epub 2014/09/16. eng.
-
(2014)
ACS Med Chem Lett
, vol.5
, Issue.9
, pp. 993-998
-
-
Zhang, Z.1
Lin, Z.2
Zhou, Z.3
Shen, H.C.4
Yan, S.F.5
Mayweg, A.V.6
Xu, Z.7
Qin, N.8
Wong, J.C.9
Zhang, Z.10
Rong, Y.11
Fry, D.C.12
Hu, T.13
-
96
-
-
84880359790
-
A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells
-
Jul 17
-
Miranda E, Nordgren IK, Male AL, Lawrence CE, Hoakwie F, Cuda F, Court W, Fox KR, Townsend PA, Packham GK, Eccles SA, Tavassoli A. A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. J Am Chem Soc. 2013 Jul 17;135(28):10418-25. PubMed PMID: 23796364. Pubmed Central PMCID: PMC3715890. Epub 2013/06/26. eng.
-
(2013)
J am Chem Soc
, vol.135
, Issue.28
, pp. 10418-10425
-
-
Miranda, E.1
Nordgren, I.K.2
Male, A.L.3
Lawrence, C.E.4
Hoakwie, F.5
Cuda, F.6
Court, W.7
Fox, K.R.8
Townsend, P.A.9
Packham, G.K.10
Eccles, S.A.11
Tavassoli, A.12
-
97
-
-
84859463451
-
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
-
Apr 3
-
Maurer T, Garrenton LS, Oh A, Pitts K, Anderson DJ, Skelton NJ, Fauber BP, Pan B, Malek S, Stokoe D, Ludlam MJ, Bowman KK, Wu J, Giannetti AM, Starovasnik MA, Mellman I, Jackson PK, Rudolph J, Wang W, Fang G. Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5299–304. PubMed PMID: 22431598. Pubmed Central PMCID: PMC3325706. Epub 2012/03/21. eng.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.14
, pp. 5299-5304
-
-
Maurer, T.1
Garrenton, L.S.2
Oh, A.3
Pitts, K.4
Erson, D.J.5
Skelton, N.J.6
Fauber, B.P.7
Pan, B.8
Malek, S.9
Stokoe, D.10
Ludlam, M.J.11
Bowman, K.K.12
Wu, J.13
Giannetti, A.M.14
Starovasnik, M.A.15
Mellman, I.16
Jackson, P.K.17
Rudolph, J.18
Wang, W.19
Fang, G.20
more..
-
98
-
-
84928957792
-
Inhibition of Ras signaling by blocking Ras-effector interactions with cyclic peptides
-
Jun 22
-
Upadhyaya P, Qian Z, Selner NG, Clippinger SR, Wu Z, Briesewitz R, Pei D. Inhibition of Ras signaling by blocking Ras-effector interactions with cyclic peptides. Angew Chem Int Ed Engl. 2015 Jun 22;54(26):7602-6. PubMed PMID: 25950772. Pubmed Central PMCID: PMC4591930. Epub 2015/05/08. eng.
-
(2015)
Angew Chem Int Ed Engl
, vol.54
, Issue.26
, pp. 7602-7606
-
-
Upadhyaya, P.1
Qian, Z.2
Selner, N.G.3
Clippinger, S.R.4
Wu, Z.5
Briesewitz, R.6
Pei, D.7
-
99
-
-
84929429281
-
Targeted delivery of brain-derived neurotrophic factor for the treatment of blindness and deafness
-
04/30
-
Khalin I, Alyautdin R, Kocherga G, Bakar MA. Targeted delivery of brain-derived neurotrophic factor for the treatment of blindness and deafness. International Journal of Nanomedicine. 2015 04/30;10:3245–67. PubMed PMID: PMC4425321.
-
(2015)
International Journal of Nanomedicine
, vol.10
, pp. 3245-3267
-
-
Khalin, I.1
Alyautdin, R.2
Kocherga, G.3
Bakar, M.A.4
-
101
-
-
0037477393
-
Design of potent peptide mimetics of brain-derived neurotrophic factor
-
O’Leary PD, Hughes RA. Design of potent peptide mimetics of brain-derived neurotrophic factor. J Biol Chem. 2003;278(28):25738–44.
-
(2003)
J Biol Chem
, vol.278
, Issue.28
, pp. 25738-25744
-
-
O’Leary, P.D.1
Hughes, R.A.2
-
102
-
-
79955404847
-
A cyclic undecamer peptide mimics a turn in folded Alzheimer amyloid β and elicits antibodies against oligomeric and fibrillar amyloid and plaques
-
Hoogerhout P, Kamphuis W, Brugghe HF, Sluijs JA, Timmermans HAM, Westdijk J, Zomer G, Boog CJP, Hol EM, van den Dobbelsteen GPJM. A cyclic undecamer peptide mimics a turn in folded Alzheimer amyloid β and elicits antibodies against oligomeric and fibrillar amyloid and plaques. PLoS One. 2011;6(4):e19110.
-
(2011)
Plos One
, vol.6
, Issue.4
-
-
Hoogerhout, P.1
Kamphuis, W.2
Brugghe, H.F.3
Sluijs, J.A.4
Timmermans, H.5
Westdijk, J.6
Zomer, G.7
Boog, C.8
Hol, E.M.9
Van Den Dobbelsteen, G.P.J.M.10
-
103
-
-
84953868005
-
Therapeutic strategies for Alzheimer’s disease in clinical trials
-
Feb
-
Godyn J, Jonczyk J, Panek D, Malawska B. Therapeutic strategies for Alzheimer’s disease in clinical trials. Pharmacol Rep. 2016 Feb;68(1):127–38. PubMed PMID: 26721364. Epub 2016/01/02. eng.
-
(2016)
Pharmacol Rep
, vol.68
, Issue.1
, pp. 127-138
-
-
Godyn, J.1
Jonczyk, J.2
Panek, D.3
Malawska, B.4
-
104
-
-
84958772667
-
Current and novel therapeutic molecules and targets in Alzheimer’s disease
-
Jan
-
Kumar A, Nisha CM, Silakari C, Sharma I, Anusha K, Gupta N, Nair P, Tripathi T, Kumar A. Current and novel therapeutic molecules and targets in Alzheimer’s disease. J Formos Med Assoc. 2016 Jan;115(1):3–10. PubMed PMID: 26220908. Epub 2015/07/30. eng.
-
(2016)
J Formos Med Assoc
, vol.115
, Issue.1
, pp. 3-10
-
-
Kumar, A.1
Nisha, C.M.2
Silakari, C.3
Sharma, I.4
Anusha, K.5
Gupta, N.6
Nair, P.7
Tripathi, T.8
Kumar, A.9
-
105
-
-
0030978915
-
Bioactive peptide design based on protein surface epitopes. A cyclic heptapeptide mimics CD4 domain 1 CC’ loop and inhibits CD4 biological function
-
May 2
-
Satoh T, Aramini JM, Li S, Friedman TM, Gao J, Edling AE, Townsend R, Koch U, Choksi S, Germann MW, Korngold R, Huang Z. Bioactive peptide design based on protein surface epitopes. A cyclic heptapeptide mimics CD4 domain 1 CC’ loop and inhibits CD4 biological function. J Biol Chem. 1997 May 2;272(18):12175–80. PubMed PMID: 9115290. Epub 1997/05/02. eng.
-
(1997)
J Biol Chem
, vol.272
, Issue.18
, pp. 12175-12180
-
-
Satoh, T.1
Aramini, J.M.2
Li, S.3
Friedman, T.M.4
Gao, J.5
Edling, A.E.6
Townsend, R.7
Koch, U.8
Choksi, S.9
Germann, M.W.10
Korngold, R.11
Huang, Z.12
-
106
-
-
84876910443
-
The integration of T cell migration, differentiation and function
-
May
-
Masopust D, Schenkel JM. The integration of T cell migration, differentiation and function. Nat Rev Immunol. 2013 May;13(5):309–20. PubMed PMID: 23598650. Epub 2013/04/20. eng.
-
(2013)
Nat Rev Immunol
, vol.13
, Issue.5
, pp. 309-320
-
-
Masopust, D.1
Schenkel, J.M.2
-
107
-
-
1542375100
-
Inhibition of ICAM-1/LFA-1-mediated heterotypic T-cell adhesion to epithelial cells: Design of ICAM-1 cyclic peptides
-
Mar 22
-
Anderson ME, Yakovleva T, Hu Y, Siahaan TJ. Inhibition of ICAM-1/LFA-1-mediated heterotypic T-cell adhesion to epithelial cells: design of ICAM-1 cyclic peptides. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1399–402. PubMed PMID: 15006370. Epub 2004/03/10. eng.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, Issue.6
, pp. 1399-1402
-
-
Anderson, M.E.1
Yakovleva, T.2
Hu, Y.3
Siahaan, T.J.4
-
108
-
-
0036546501
-
NF-kappaB in cancer: From innocent bystander to major culprit
-
Apr
-
Karin M, Cao Y, Greten FR, Li ZW. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer. 2002 Apr;2(4):301–10. PubMed PMID: 12001991. Epub 2002/05/11. eng.
-
(2002)
Nat Rev Cancer
, vol.2
, Issue.4
, pp. 301-310
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
Li, Z.W.4
-
109
-
-
80052014052
-
Inflammation meets cancer, with NF-kappaB as the matchmaker
-
Aug
-
Ben-Neriah Y, Karin M. Inflammation meets cancer, with NF-kappaB as the matchmaker. Nat Immunol. 2011 Aug;12(8):715–23. PubMed PMID: 21772280. Epub 2011/07/21. eng.
-
(2011)
Nat Immunol
, vol.12
, Issue.8
, pp. 715-723
-
-
Ben-Neriah, Y.1
Karin, M.2
-
110
-
-
84873615156
-
The nuclear factor kappa-B signaling pathway as a therapeutic target against thyroid cancers
-
Feb
-
Li X, Abdel-Mageed AB, Mondal D, Kandil E. The nuclear factor kappa-B signaling pathway as a therapeutic target against thyroid cancers. Thyroid. 2013 Feb;23(2):209–18. PubMed PMID: 23273524. Epub 2013/01/01. eng.
-
(2013)
Thyroid
, vol.23
, Issue.2
, pp. 209-218
-
-
Li, X.1
Abdel-Mageed, A.B.2
Mondal, D.3
Kandil, E.4
-
111
-
-
84925668843
-
Role in inflammation associated gastrointestinal malignancies
-
Mar 21
-
Gambhir S, Vyas D, Hollis M, Aekka A, Vyas A. Nuclear factor kappa B role in inflammation associated gastrointestinal malignancies. World J Gastroenterol. 2015 Mar 21;21(11):3174–83. PubMed PMID: 25805923. Pubmed Central PMCID: PMC4363746. Epub 2015/03/26. eng.
-
(2015)
World J Gastroenterol
, vol.21
, Issue.11
, pp. 3174-3183
-
-
Gambhir, S.1
Vyas, D.2
Hollis, M.3
Aekka, A.4
Vyas, A.5
Nuclear Factor Kappa, B.6
-
112
-
-
0037328613
-
NF-kappaB activation in cancer: A challenge for ubiquitination-and proteasome-based therapeutic approach
-
Feb
-
Amit S, Ben-Neriah Y. NF-kappaB activation in cancer: a challenge for ubiquitination-and proteasome-based therapeutic approach. Semin Cancer Biol. 2003 Feb;13(1):15–28. PubMed PMID: 12507553.
-
(2003)
Semin Cancer Biol
, vol.13
, Issue.1
, pp. 15-28
-
-
Amit, S.1
Ben-Neriah, Y.2
-
113
-
-
0030731146
-
Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase
-
Nov 3
-
Yaron A, Gonen H, Alkalay I, Hatzubai A, Jung S, Beyth S, Mercurio F, Manning AM, Ciechanover A, Ben-Neriah Y. Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase. EMBO J. 1997 Nov 3;16(21):6486–94. PubMed PMID: 9351830.
-
(1997)
EMBO J
, vol.16
, Issue.21
, pp. 6486-6494
-
-
Yaron, A.1
Gonen, H.2
Alkalay, I.3
Hatzubai, A.4
Jung, S.5
Beyth, S.6
Mercurio, F.7
Manning, A.M.8
Ciechanover, A.9
Ben-Neriah, Y.10
-
114
-
-
80053357273
-
The emerging role of nuclear factor kappa B in renal cell carcinoma
-
Nov
-
Morais C, Gobe G, Johnson DW, Healy H. The emerging role of nuclear factor kappa B in renal cell carcinoma. Int J Biochem Cell Biol. 2011 Nov;43(11):1537–49. PubMed PMID: 21854869. Epub 2011/08/23. eng.
-
(2011)
Int J Biochem Cell Biol
, vol.43
, Issue.11
, pp. 1537-1549
-
-
Morais, C.1
Gobe, G.2
Johnson, D.W.3
Healy, H.4
-
115
-
-
84856259390
-
Inhibitory kappa B kinases as targets for pharmacological regulation
-
12/01/received 06/20/revised 07/02/accepted
-
Gamble C, McIntosh K, Scott R, Ho KH, Plevin R, Paul A. Inhibitory kappa B kinases as targets for pharmacological regulation. Br J Pharmacol. 2012 12/01/received 06/20/revised 07/02/accepted;165(4):802–19. PubMed PMID: PMC3312479.
-
(2012)
Br J Pharmacol
, vol.165
, Issue.4
, pp. 802-819
-
-
Gamble, C.1
McIntosh, K.2
Scott, R.3
Ho, K.H.4
Plevin, R.5
Paul, A.6
-
116
-
-
84921324809
-
Understanding HIV latency: The road to an HIV cure
-
Dahabieh MS, Battivelli E, Verdin E. Understanding HIV latency: the road to an HIV cure. Annu Rev Med. 2015;66:407–21. PubMed PMID: 25587657. Pubmed Central PMCID: PMC4381961. Epub 2015/01/15. eng.
-
(2015)
Annu Rev Med
, vol.66
, pp. 407-421
-
-
Dahabieh, M.S.1
Battivelli, E.2
Verdin, E.3
-
118
-
-
79851483767
-
Tits and bits of HIV Tat protein
-
Mar
-
Johri MK, Mishra R, Chhatbar C, Unni SK, Singh SK. Tits and bits of HIV Tat protein. Expert Opin Biol Ther. 2011 Mar;11(3):269–83. PubMed PMID: 21204735. Epub 2011/01/06. eng.
-
(2011)
Expert Opin Biol Ther
, vol.11
, Issue.3
, pp. 269-283
-
-
Johri, M.K.1
Mishra, R.2
Chhatbar, C.3
Unni, S.K.4
Singh, S.K.5
-
119
-
-
84856772777
-
The ins and outs of HIV-1 Tat
-
Mar
-
Debaisieux S, Rayne F, Yezid H, Beaumelle B. The ins and outs of HIV-1 Tat. Traffic (Copenhagen, Denmark). 2012 Mar;13(3):355–63. PubMed PMID: 21951552. Epub 2011/09/29. eng.
-
(2012)
Traffic (Copenhagen, Denmark)
, vol.13
, Issue.3
, pp. 355-363
-
-
Debaisieux, S.1
Rayne, F.2
Yezid, H.3
Beaumelle, B.4
-
120
-
-
84930984538
-
HIV-1 proteins, Tat and gp120, target the developing dopamine system
-
Fitting S, Booze RM, Mactutus CF. HIV-1 proteins, Tat and gp120, target the developing dopamine system. Curr HIV Res. 2015;13(1):21–42. PubMed PMID: 25613135. Pubmed Central PMCID: PMC4467793. Epub 2015/01/24. eng.
-
(2015)
Curr HIV Res
, vol.13
, Issue.1
, pp. 21-42
-
-
Fitting, S.1
Booze, R.M.2
Mactutus, C.F.3
-
121
-
-
67749088605
-
Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein
-
Jul 21
-
Davidson A, Leeper TC, Athanassiou Z, Patora-Komisarska K, Karn J, Robinson JA, Varani G. Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):11931–6. PubMed PMID: 19584251. Pubmed Central PMCID: PMC2715490. Epub 2009/07/09. eng.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.29
, pp. 11931-11936
-
-
Davidson, A.1
Leeper, T.C.2
Athanassiou, Z.3
Patora-Komisarska, K.4
Karn, J.5
Robinson, J.A.6
Varani, G.7
-
122
-
-
79958036685
-
Inhibition of both HIV-1 reverse transcription and gene expression by a cyclic peptide that binds the Tat-transactivating response element (TAR) RNA
-
Lalonde MS, Lobritz MA, Ratcliff A, Chamanian M, Athanassiou Z, Tyagi M, Wong J, Robinson JA, Karn J, Varani G, Arts EJ. Inhibition of both HIV-1 reverse transcription and gene expression by a cyclic peptide that binds the Tat-transactivating response element (TAR) RNA. PLoS Pathog. 2011;7(5):e1002038.
-
(2011)
Plos Pathog
, vol.7
, Issue.5
-
-
Lalonde, M.S.1
Lobritz, M.A.2
Ratcliff, A.3
Chamanian, M.4
Athanassiou, Z.5
Tyagi, M.6
Wong, J.7
Robinson, J.A.8
Karn, J.9
Varani, G.10
Arts, E.J.11
-
123
-
-
84914176382
-
How HIV-1 Gag assembles in cells: Putting together pieces of the puzzle
-
Lingappa JR, Reed JC, Tanaka M, Chutiraka K, Robinson BA. How HIV-1 Gag assembles in cells: putting together pieces of the puzzle. Virus Res. 2014;193:89–107.
-
(2014)
Virus Res
, vol.193
, pp. 89-107
-
-
Lingappa, J.R.1
Reed, J.C.2
Tanaka, M.3
Chutiraka, K.4
Robinson, B.A.5
-
124
-
-
84937252674
-
HIV-1 assembly, release and maturation
-
Freed EO. HIV-1 assembly, release and maturation. Nat Rev Micro. 2015;13(8):484–96.
-
(2015)
Nat Rev Micro
, vol.13
, Issue.8
, pp. 484-496
-
-
Freed, E.O.1
-
125
-
-
0033520487
-
In vivo protein transduction: Delivery of a biologically active protein into the mouse
-
Sep 3
-
Schwarze SR, Ho A, Vocero-Akbani A, Dowdy SF. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science. 1999 Sep 3;285(5433):1569–72. PubMed PMID: 10477521.
-
(1999)
Science
, vol.285
, Issue.5433
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
126
-
-
84989879590
-
Recent in vivo advances in cell-penetrating peptide-assisted drug delivery
-
Dec 3
-
Kurrikof KSR, Gestin MPS, Langel UP. Recent in vivo advances in cell-penetrating peptide-assisted drug delivery. Expert opinion on drug delivery. 2015 Dec 3;22:1–15. PubMed PMID: 26634750. Epub 2015/12/05. Eng.
-
(2015)
Expert Opinion on Drug Delivery
, vol.22
, pp. 1-15
-
-
Kurrikof, K.1
Gestin, M.2
Langel, U.P.3
-
127
-
-
58949086238
-
Inhibition of HIV budding by a genetically selected cyclic peptide targeting the Gag-TSG101 interaction
-
Dec 19
-
Tavassoli A, Lu Q, Gam J, Pan H, Benkovic SJ, Cohen SN. Inhibition of HIV budding by a genetically selected cyclic peptide targeting the Gag-TSG101 interaction. ACS Chem Biol. 2008 Dec 19;3(12):757–64. PubMed PMID: 19053244. Epub 2008/12/05. eng.
-
(2008)
ACS Chem Biol
, vol.3
, Issue.12
, pp. 757-764
-
-
Tavassoli, A.1
Lu, Q.2
Gam, J.3
Pan, H.4
Benkovic, S.J.5
Cohen, S.N.6
-
128
-
-
84989843952
-
Multifunctional facets of retrovirus integrase
-
Aug 26
-
Grandgenett DP, Pandey KK, Bera S, Aihara H. Multifunctional facets of retrovirus integrase. World J Biol Chem. 2015 Aug 26;6(3):83–94. PubMed PMID: 26322168. Pubmed Central PMCID: PMC4549773. Epub 2015/09/01. eng.
-
(2015)
World J Biol Chem
, vol.6
, Issue.3
, pp. 83-94
-
-
Grandgenett, D.P.1
Pandey, K.K.2
Bera, S.3
Aihara, H.4
-
129
-
-
84947031020
-
Development of HIV-1 integrase inhibitors: Recent molecular modeling perspectives
-
Nov
-
Su M, Tan J, Lin CY. Development of HIV-1 integrase inhibitors: recent molecular modeling perspectives. Drug discovery today. 2015 Nov;20(11):1337–48. PubMed PMID: 26220090. Epub 2015/07/30. eng.
-
(2015)
Drug Discovery Today
, vol.20
, Issue.11
, pp. 1337-1348
-
-
Su, M.1
Tan, J.2
Lin, C.Y.3
-
130
-
-
84943382063
-
Clinical effectiveness of dolutegravir in the treatment of HIV/AIDS
-
Taha H, Das A, Das S. Clinical effectiveness of dolutegravir in the treatment of HIV/AIDS. Infection and drug resistance. 2015;8:339–52. PubMed PMID: 26491363. Pubmed Central PMCID: PMC4598225. Epub 2015/10/23. eng.
-
(2015)
Infection and Drug Resistance
, vol.8
, pp. 339-352
-
-
Taha, H.1
Das, A.2
Das, S.3
-
131
-
-
78249283226
-
Cyclic peptide inhibitors of HIV-1 integrase derived from the LEDGF/p75 protein
-
Oct 1
-
Hayouka Z, Hurevich M, Levin A, Benyamini H, Iosub A, Maes M, Shalev DE, Loyter A, Gilon C, Friedler A. Cyclic peptide inhibitors of HIV-1 integrase derived from the LEDGF/p75 protein. Bioorg Med Chem. 2010 Oct 1;18(23):8388–95. PubMed PMID: 20974536. Epub 2010/10/27. Eng.
-
(2010)
Bioorg Med Chem
, vol.18
, Issue.23
, pp. 8388-8395
-
-
Hayouka, Z.1
Hurevich, M.2
Levin, A.3
Benyamini, H.4
Iosub, A.5
Maes, M.6
Shalev, D.E.7
Loyter, A.8
Gilon, C.9
Friedler, A.10
-
132
-
-
78650896236
-
Imperial S. Design of novel ligands of CDP-methylerythritol kinase by mimicking direct protein-protein and solvent-mediated interactions
-
Jan–Feb
-
Gimenez-Oya V, Villacanas O, Obiol-Pardo C, Antolin-Llovera M, Rubio-Martinez J, Imperial S. Design of novel ligands of CDP-methylerythritol kinase by mimicking direct protein-protein and solvent-mediated interactions. J Mol Recognit. 2011 Jan–Feb;24(1):71–80. PubMed PMID: 20213667. Epub 2010/03/10. eng.
-
(2011)
J Mol Recognit
, vol.24
, Issue.1
, pp. 71-80
-
-
Gimenez-Oya, V.1
Villacanas, O.2
Obiol-Pardo, C.3
Antolin-Llovera, M.4
Rubio-Martinez, J.5
-
133
-
-
84894431432
-
Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction
-
Feb 6
-
Glas A, Bier D, Hahne G, Rademacher C, Ottmann C, Grossmann TN. Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction. Angew Chem Int Ed Engl. 2014 Feb 6;53(9):2489–93. PubMed PMID: 24504455. Epub 2014/02/08. Eng.
-
(2014)
Angew Chem Int Ed Engl
, vol.53
, Issue.9
, pp. 2489-2493
-
-
Glas, A.1
Bier, D.2
Hahne, G.3
Rademacher, C.4
Ottmann, C.5
Grossmann, T.N.6
-
134
-
-
84883413392
-
Cyclic peptide inhibitors of the β-sliding clamp in Staphylococcus aureus
-
Kjelstrup S, Hansen PMP, Thomsen LE, Hansen PR, Løbner-Olesen A. Cyclic peptide inhibitors of the β-sliding clamp in Staphylococcus aureus. PLoS One. 2013;8(9):e72273.
-
(2013)
Plos One
, vol.8
, Issue.9
-
-
Kjelstrup, S.1
Hansen, P.2
Thomsen, L.E.3
Hansen, P.R.4
Løbner-Olesen, A.5
-
135
-
-
34247245116
-
Characterization and NMR solution structure of a novel cyclic pentapeptide inhibitor of pathogenic hantaviruses
-
Mar
-
Hall PR, Malone L, Sillerud LO, Ye C, Hjelle BL, Larson RS. Characterization and NMR solution structure of a novel cyclic pentapeptide inhibitor of pathogenic hantaviruses. Chem Biol Drug Des. 2007 Mar;69(3):180-90. PubMed PMID: 17441904. Epub 2007/04/20. eng.
-
(2007)
Chem Biol Drug Des
, vol.69
, Issue.3
, pp. 180-190
-
-
Hall, P.R.1
Malone, L.2
Sillerud, L.O.3
Ye, C.4
Hjelle, B.L.5
Larson, R.S.6
-
136
-
-
0031761325
-
Peptide modulators of protein-protein interactions in intracellular signaling
-
Oct
-
Souroujon MC, Mochly-Rosen D. Peptide modulators of protein-protein interactions in intracellular signaling. Nat Biotechnol. 1998 Oct;16(10):919–24. PubMed PMID: 9788346.
-
(1998)
Nat Biotechnol
, vol.16
, Issue.10
, pp. 919-924
-
-
Souroujon, M.C.1
Mochly-Rosen, D.2
-
137
-
-
78649275318
-
Highly specific modulators of protein kinase C localization: Applications to heart failure
-
Qvit N, Mochly-Rosen D. Highly specific modulators of protein kinase C localization: applications to heart failure. Drug Discov Today Dis Mech. 2010;7(2):e87–e93.
-
(2010)
Drug Discov Today Dis Mech
, vol.7
, Issue.2
, pp. e87-e93
-
-
Qvit, N.1
Mochly-Rosen, D.2
-
138
-
-
84959243441
-
Scaffold Proteins LACK and TRACK as Potential Drug Targets in Kinetoplastid Parasites: Development of Inhibitors
-
Qvit N, Schechtman D, Peña DA, Berti DA, Soares CO, Miao Q, Liang L, Baron LA, Teh-Poot C, Martínez-Vega P, Ramirez-Sierra MJ, Churchill E, Cunningham AD, Malkovskiy AV, Federspiel NA, et al. Scaffold Proteins LACK and TRACK as Potential Drug Targets in Kinetoplastid Parasites: Development of Inhibitors. International Journal for Parasitology: Drugs and Drug Resistance. 2016;6:74-84.
-
(2016)
International Journal for Parasitology: Drugs and Drug Resistance
, vol.6
, pp. 74-84
-
-
Qvit, N.1
Schechtman, D.2
Peña, D.A.3
Berti, D.A.4
Soares, C.O.5
Miao, Q.6
Liang, L.7
Baron, L.A.8
Teh-Poot, C.9
Martínez-Vega, P.10
Ramirez-Sierra, M.J.11
Churchill, E.12
Cunningham, A.D.13
Malkovskiy, A.V.14
Federspiel, N.A.15
-
139
-
-
84976346966
-
Selective Phosphorylation Inhibitor of Delta Protein Kinase C−Pyruvate Dehydrogenase Kinase Protein−Protein Interactions: Application for Myocardial Injury in Vivo
-
Qvit N, Disatnik MH, Sho J, Mochly-Rosen D. Selective Phosphorylation Inhibitor of Delta Protein Kinase C−Pyruvate Dehydrogenase Kinase Protein−Protein Interactions: Application for Myocardial Injury in Vivo. J Am Chem Soc. 2016;138(24):7626-35.
-
(2016)
J am Chem Soc
, vol.138
, Issue.24
, pp. 7626-7635
-
-
Qvit, N.1
Disatnik, M.H.2
Sho, J.3
Mochly-Rosen, D.4
|