-
1
-
-
0033574774
-
Aminoacyl-CoAs as probes of condensation domain selectivity in nonribosomal peptide synthesis
-
Belshaw, P. J., C. T. Walsh, and T. Stachelhaus. 1999. Aminoacyl-CoAs as probes of condensation domain selectivity in nonribosomal peptide synthesis. Science 284:486-489.
-
(1999)
Science
, vol.284
, pp. 486-489
-
-
Belshaw, P.J.1
Walsh, C.T.2
Stachelhaus, T.3
-
2
-
-
0036120595
-
Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE
-
Bruner, S. D., T. Weber, R. M. Kohli, D. Schwarzer, M. A. Marahiel, C. T. Walsh, and M. T. Stubbs. 2002. Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE. Structure (Cambridge) 10:301-310.
-
(2002)
Structure (Cambridge)
, vol.10
, pp. 301-310
-
-
Bruner, S.D.1
Weber, T.2
Kohli, R.M.3
Schwarzer, D.4
Marahiel, M.A.5
Walsh, C.T.6
Stubbs, M.T.7
-
3
-
-
0037746922
-
Synthesis of tyrocidine A and its analogues by spontaneous cyclization in aqueous solution
-
Bu, X., X. Wu, G. Xie, and Z. Guo. 2002. Synthesis of tyrocidine A and its analogues by spontaneous cyclization in aqueous solution. Org. Lett. 4:2893-2895.
-
(2002)
Org. Lett.
, vol.4
, pp. 2893-2895
-
-
Bu, X.1
Wu, X.2
Xie, G.3
Guo, Z.4
-
4
-
-
0030756031
-
Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S
-
Conti, E., T. Stachelhaus, M. A. Marahiel, and P. Brick. 1997. Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S. EMBO J. 16:4174-4183.
-
(1997)
EMBO J.
, vol.16
, pp. 4174-4183
-
-
Conti, E.1
Stachelhaus, T.2
Marahiel, M.A.3
Brick, P.4
-
5
-
-
0038492655
-
Structures of naturally occurring circular proteins from bacteria
-
Craik, D. J., N. L. Daly, I. Saska, M. Trabi, and K. J. Rosengren. 2003. Structures of naturally occurring circular proteins from bacteria. J. Bacteriol. 185:4011-4021.
-
(2003)
J. Bacteriol.
, vol.185
, pp. 4011-4021
-
-
Craik, D.J.1
Daly, N.L.2
Saska, I.3
Trabi, M.4
Rosengren, K.J.5
-
6
-
-
0039194307
-
Streptogramin B biosynthesis in Streptomyces pristinaespiralis and Streptomyces virginiae: Molecular characterization of the last structural peptide synthetase gene
-
de Crecy-Lagard, V., W. Saurin, D. Thibaut, P. Gil, L. Naudin, J. Crouzet, and V. Blanc. 1997. Streptogramin B biosynthesis in Streptomyces pristinaespiralis and Streptomyces virginiae: molecular characterization of the last structural peptide synthetase gene. Antimicrob. Agents Chemother. 41:1904-1909.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1904-1909
-
-
De Crecy-Lagard, V.1
Saurin, W.2
Thibaut, D.3
Gil, P.4
Naudin, L.5
Crouzet, J.6
Blanc, V.7
-
7
-
-
0028896569
-
Expression of an active adenylate-forming domain of peptide synthetases corresponding to acyl-CoA-synthetases
-
Dieckmann, R., Y. O. Lee, H. van Liempt, H. von Dohren, and H. Kleinkauf. 1995. Expression of an active adenylate-forming domain of peptide synthetases corresponding to acyl-CoA-synthetases. FEBS Lett. 357:212-216.
-
(1995)
FEBS Lett.
, vol.357
, pp. 212-216
-
-
Dieckmann, R.1
Lee, Y.O.2
Van Liempt, H.3
Von Dohren, H.4
Kleinkauf, H.5
-
8
-
-
13044260223
-
The mycosubtilin synthetase of Bacillus subtilis ATCC6633: A multifunctional hybrid between a peptide synthetase, an amino transferase, and a fatty acid synthase
-
Duitman, E. H., L. W. Hamoen, M. Rembold, G. Venema, H. Seitz, W. Saenger, F. Bernhard, R. Reinhardt, M. Schmidt, C. Ullrich, T. Stein, F. Leenders, and J. Vater. 1999. The mycosubtilin synthetase of Bacillus subtilis ATCC6633: a multifunctional hybrid between a peptide synthetase, an amino transferase, and a fatty acid synthase. Proc. Natl. Acad. Sci. USA 96:13294-13299.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13294-13299
-
-
Duitman, E.H.1
Hamoen, L.W.2
Rembold, M.3
Venema, G.4
Seitz, H.5
Saenger, W.6
Bernhard, F.7
Reinhardt, R.8
Schmidt, M.9
Ullrich, C.10
Stein, T.11
Leenders, F.12
Vater, J.13
-
9
-
-
0032562142
-
Reconstitution and characterization of the Escherichia coli enterobactin synthetase from EntB, EntE, and EntF
-
Gehring, A. M., I. Mori, and C. T. Walsh. 1998. Reconstitution and characterization of the Escherichia coli enterobactin synthetase from EntB, EntE, and EntF. Biochemistry 37:2648-2659.
-
(1998)
Biochemistry
, vol.37
, pp. 2648-2659
-
-
Gehring, A.M.1
Mori, I.2
Walsh, C.T.3
-
11
-
-
0036295033
-
The structure of VibH represents nonribosomal peptide synthetase condensation, cyclization and epimerization domains
-
Keating, T. A., C. G. Marshall, C. T. Walsh, and A. E. Keating. 2002. The structure of VibH represents nonribosomal peptide synthetase condensation, cyclization and epimerization domains. Nat. Struct. Biol. 9:522-526.
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 522-526
-
-
Keating, T.A.1
Marshall, C.G.2
Walsh, C.T.3
Keating, A.E.4
-
12
-
-
0035912883
-
Generality of peptide cyclization catalyzed by isolated thioesterase domains of nonribosomal peptide synthetases
-
Kohli, R. M., J. W. Trauger, D. Schwarzer, M. A. Marahiel, and C. T. Walsh. 2001. Generality of peptide cyclization catalyzed by isolated thioesterase domains of nonribosomal peptide synthetases. Biochemistry 40:7099-7108.
-
(2001)
Biochemistry
, vol.40
, pp. 7099-7108
-
-
Kohli, R.M.1
Trauger, J.W.2
Schwarzer, D.3
Marahiel, M.A.4
Walsh, C.T.5
-
13
-
-
0037043734
-
Biomimetic synthesis and optimization of cyclic peptide antibiotics
-
Kohli, R. M., C. T. Walsh, and M. D. Burkart. 2002. Biomimetic synthesis and optimization of cyclic peptide antibiotics. Nature 418:658-661.
-
(2002)
Nature
, vol.418
, pp. 658-661
-
-
Kohli, R.M.1
Walsh, C.T.2
Burkart, M.D.3
-
14
-
-
0031459595
-
The bacitracin biosynthesis operon of Bacillus licheniformis ATCC 10716: Molecular characterization of three multi-modular peptide synthetases
-
Konz, D., A. Klens, K. Schorgendorfer, and M. A. Marahiel. 1997. The bacitracin biosynthesis operon of Bacillus licheniformis ATCC 10716: molecular characterization of three multi-modular peptide synthetases. Chem. Biol. 4:927-937.
-
(1997)
Chem. Biol.
, vol.4
, pp. 927-937
-
-
Konz, D.1
Klens, A.2
Schorgendorfer, K.3
Marahiel, M.A.4
-
15
-
-
0030294470
-
A new enzyme superfamily - The phosphopantetheinyl transferases
-
Lambalot, R. H., A. M. Gehring, R. S. Flugel, P. Zuber, M. LaCelle, M. A. Marahiel, R. Reid, C. Khosla, and C. T. Walsh. 1996. A new enzyme superfamily - the phosphopantetheinyl transferases. Chem. Biol. 3:923-936.
-
(1996)
Chem. Biol.
, vol.3
, pp. 923-936
-
-
Lambalot, R.H.1
Gehring, A.M.2
Flugel, R.S.3
Zuber, P.4
LaCelle, M.5
Marahiel, M.A.6
Reid, R.7
Khosla, C.8
Walsh, C.T.9
-
16
-
-
0034730091
-
Control of directionality in nonribosomal peptide synthesis: Role of the condensation domain in preventing misinitiation and timing of epimerization
-
Linne, U., and M. A. Marahiel. 2000. Control of directionality in nonribosomal peptide synthesis: role of the condensation domain in preventing misinitiation and timing of epimerization. Biochemistry 39:10439-10447.
-
(2000)
Biochemistry
, vol.39
, pp. 10439-10447
-
-
Linne, U.1
Marahiel, M.A.2
-
17
-
-
0015196274
-
Polypeptide synthesis on protein templates: The enzymatic synthesis of gramicidin S and tyrocidine
-
Lipmann, F., W. Gevers, H. Kleinkauf, and R. Roskoski, Jr. 1971. Polypeptide synthesis on protein templates: the enzymatic synthesis of gramicidin S and tyrocidine. Adv. Enzymol. Relat. Areas Mol. Biol. 35:1-34.
-
(1971)
Adv. Enzymol. Relat. Areas Mol. Biol.
, vol.35
, pp. 1-34
-
-
Lipmann, F.1
Gevers, W.2
Kleinkauf, H.3
Roskoski Jr., R.4
-
18
-
-
9444278428
-
Modular peptide synthetases involved in non-ribosomal peptide synthesis
-
Marahiel, M. A., T. Stachelhaus, and H. D. Mootz. 1997. Modular peptide synthetases involved in non-ribosomal peptide synthesis. Chem. Rev. 97: 2651-2673.
-
(1997)
Chem. Rev.
, vol.97
, pp. 2651-2673
-
-
Marahiel, M.A.1
Stachelhaus, T.2
Mootz, H.D.3
-
19
-
-
0035831486
-
The dhb operon of Bacillus subtilis encodes the biosynthetic template for the catecholic siderophore 2,3-dihydroxybenzoate-glycine-threonine trimeric ester bacillibactin
-
May, J. J., T. M. Wendrich, and M. A. Marahiel. 2001. The dhb operon of Bacillus subtilis encodes the biosynthetic template for the catecholic siderophore 2,3-dihydroxybenzoate-glycine-threonine trimeric ester bacillibactin. J. Biol. Chem. 276:7209-7217.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 7209-7217
-
-
May, J.J.1
Wendrich, T.M.2
Marahiel, M.A.3
-
20
-
-
0036905773
-
Ways of assembling complex natural products on modular nonribosomal peptide synthetases
-
Mootz, H. D., D. Schwarzer, and M. A. Marahiel. 2002. Ways of assembling complex natural products on modular nonribosomal peptide synthetases. Chembiochem 3:490-504.
-
(2002)
Chembiochem.
, vol.3
, pp. 490-504
-
-
Mootz, H.D.1
Schwarzer, D.2
Marahiel, M.A.3
-
22
-
-
0033485259
-
Crystal structure of the surfactin synthetase-activating enzyme Sfp: A prototype of the 4′-phosphopantetheinyl transferase superfamily
-
Reuter, K., M. R. Mofid, M. A. Marahiel, and R. Ficner. 1999. Crystal structure of the surfactin synthetase-activating enzyme Sfp: a prototype of the 4′-phosphopantetheinyl transferase superfamily. EMBO J. 18:6823-6831.
-
(1999)
EMBO J.
, vol.18
, pp. 6823-6831
-
-
Reuter, K.1
Mofid, M.R.2
Marahiel, M.A.3
Ficner, R.4
-
23
-
-
0037384426
-
The sypA, sypS, and sypC synthetase genes encode twenty-two modules involved in the non-ribosomal peptide synthesis of syringopeptin by Pseudomonas syringae pv. syringae B301D
-
Scholz-Schroeder, B. K., J. D. Soule, and D. C. Gross. 2003. The sypA, sypS, and sypC synthetase genes encode twenty-two modules involved in the non-ribosomal peptide synthesis of syringopeptin by Pseudomonas syringae pv. syringae B301D. Mol. Plant-Microbe Interact. 16:271-280.
-
(2003)
Mol. Plant-Microbe Interact.
, vol.16
, pp. 271-280
-
-
Scholz-Schroeder, B.K.1
Soule, J.D.2
Gross, D.C.3
-
24
-
-
0035543164
-
A physical map of the syringomycin and syringopeptin gene clusters localized to an approximately 145-kb DNA region of Pseudomonas syringae pv. syringae strain B301D
-
Scholz-Schroeder, B. K., J. D. Soule, S. E. Lu, I. Grgurina, and D. C. Gross. 2001. A physical map of the syringomycin and syringopeptin gene clusters localized to an approximately 145-kb DNA region of Pseudomonas syringae pv. syringae strain B301D. Mol. Plant-Microbe Interact. 14:1426-1435.
-
(2001)
Mol. Plant-Microbe Interact.
, vol.14
, pp. 1426-1435
-
-
Scholz-Schroeder, B.K.1
Soule, J.D.2
Lu, S.E.3
Grgurina, I.4
Gross, D.C.5
-
26
-
-
0024474276
-
The structure of syringomycins A1, E and G
-
Segre, A., R. C. Bachmann, A. Ballio, F. Bossa, I. Grgurina, N. S. Iacobellis, G. Marino, P. Pucci, M. Simmaco, and J. Y. Takemoto. 1989. The structure of syringomycins A1, E and G. FEBS Lett. 255:27-31.
-
(1989)
FEBS Lett.
, vol.255
, pp. 27-31
-
-
Segre, A.1
Bachmann, R.C.2
Ballio, A.3
Bossa, F.4
Grgurina, I.5
Iacobellis, N.S.6
Marino, G.7
Pucci, P.8
Simmaco, M.9
Takemoto, J.Y.10
-
27
-
-
0033150199
-
Assembly line enzymology by multimodular nonribosomal peptide synthetases: The thioesterase domain of E. coli EntF catalyzes both elongation and cyclolactonization
-
Shaw-Reid, C. A., N. L. Kelleher, H. C. Losey, A. M. Gehring, C. Berg, and C. T. Walsh. 1999. Assembly line enzymology by multimodular nonribosomal peptide synthetases: the thioesterase domain of E. coli EntF catalyzes both elongation and cyclolactonization. Chem. Biol. 6:385-400.
-
(1999)
Chem. Biol.
, vol.6
, pp. 385-400
-
-
Shaw-Reid, C.A.1
Kelleher, N.L.2
Losey, H.C.3
Gehring, A.M.4
Berg, C.5
Walsh, C.T.6
-
28
-
-
0042233828
-
Loading peptidylcoenzyme A onto peptidyl carrier proteins: A novel approach in characterizing macrocyclization by thioesterase domains
-
Sieber, S. A., C. T. Walsh, and M. A. Marahiel. 2003. Loading peptidylcoenzyme A onto peptidyl carrier proteins: a novel approach in characterizing macrocyclization by thioesterase domains. J. Am. Chem. Soc. 125: 10862-10866.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 10862-10866
-
-
Sieber, S.A.1
Walsh, C.T.2
Marahiel, M.A.3
-
29
-
-
0030292865
-
Biochemical characterization of peptidyl carrier protein (PCP), the thiolation domain of multifunctional peptide synthetases
-
Stachelhaus, T., A. Hüser, and M. A. Marahiel. 1996. Biochemical characterization of peptidyl carrier protein (PCP), the thiolation domain of multifunctional peptide synthetases. Chem. Biol. 3:913-921.
-
(1996)
Chem. Biol.
, vol.3
, pp. 913-921
-
-
Stachelhaus, T.1
Hüser, A.2
Marahiel, M.A.3
-
30
-
-
0034648798
-
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
-
Trauger, J., R. Kohli, H. Mootz, M. Marahiel, and C. Walsh. 2000. Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase. Nature 407:215-218.
-
(2000)
Nature
, vol.407
, pp. 215-218
-
-
Trauger, J.1
Kohli, R.2
Mootz, H.3
Marahiel, M.4
Walsh, C.5
-
31
-
-
0035912930
-
Cyclization of backbone-substituted peptides catalyzed by the thioesterase domain from the tyrocidine nonribosomal peptide synthetase
-
Trauger, J. W., R. M. Kohli, and C. T. Walsh. 2001. Cyclization of backbone-substituted peptides catalyzed by the thioesterase domain from the tyrocidine nonribosomal peptide synthetase. Biochemistry 40:7092-7098.
-
(2001)
Biochemistry
, vol.40
, pp. 7092-7098
-
-
Trauger, J.W.1
Kohli, R.M.2
Walsh, C.T.3
-
32
-
-
0037069317
-
Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase
-
Tseng, C. C., S. D. Bruner, R. M. Kohli, M. A. Marahiel, C. T. Walsh, and S. A. Sieber. 2002. Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase. Biochemistry 41:13350-13359.
-
(2002)
Biochemistry
, vol.41
, pp. 13350-13359
-
-
Tseng, C.C.1
Bruner, S.D.2
Kohli, R.M.3
Marahiel, M.A.4
Walsh, C.T.5
Sieber, S.A.6
-
33
-
-
0022457256
-
Fengycin - A novel antifungal lipopeptide antibiotic produced by Bacillus subtilis F-29-3
-
Vanittanakom, N., W. Loeffler, U. Koch, and G. Jung. 1986. Fengycin - a novel antifungal lipopeptide antibiotic produced by Bacillus subtilis F-29-3. J. Antibiot. (Tokyo) 39:888-901.
-
(1986)
J. Antibiot. (Tokyo)
, vol.39
, pp. 888-901
-
-
Vanittanakom, N.1
Loeffler, W.2
Koch, U.3
Jung, G.4
-
34
-
-
0042908666
-
-
ASM Press, Washington, D.C.
-
Walsh, C. T. 2003. Antibiotics: actions, origins, and resistance, p. 195-220. ASM Press, Washington, D.C.
-
(2003)
Antibiotics: Actions, Origins, and Resistance
, pp. 195-220
-
-
Walsh, C.T.1
-
35
-
-
0028251292
-
Disruption of the cyclosporin synthetase gene of Tolypocladium niveum
-
Weber, G., and E. Leitner. 1994. Disruption of the cyclosporin synthetase gene of Tolypocladium niveum. Curr. Genet. 26:461-467.
-
(1994)
Curr. Genet.
, vol.26
, pp. 461-467
-
-
Weber, G.1
Leitner, E.2
-
36
-
-
0034656331
-
Solution structure of PCP, a prototype for the peptidyl carrier domains of modular peptide synthetases
-
Weber, T., R. Baumgartner, C. Renner, M. A. Marahiel, and T. A. Holak. 2000. Solution structure of PCP, a prototype for the peptidyl carrier domains of modular peptide synthetases. Struct. Fold Des. 8:407-418.
-
(2000)
Struct. Fold Des.
, vol.8
, pp. 407-418
-
-
Weber, T.1
Baumgartner, R.2
Renner, C.3
Marahiel, M.A.4
Holak, T.A.5
|