Cyclic peptide inhibitors of HIV-1 integrase derived from the LEDGF/p75 protein

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 23, 2010, Pages 8388-8395

  Hayouka, Zvi ^a   Hurevich, Mattan ^a   Levin, Aviad ^a   Benyamini, Hadar ^a   Iosub, Anat ^a   Maes, Michal ^a   Shalev, Deborah E ^a   Loyter, Abraham ^a   Gilon, Chaim ^a   Friedler, Assaf ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Cyclic peptides; HIV 1; Intergase inhibitors; NMR; Protein mimetics; Protein protein interactions

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CYCLOPEPTIDE; INTEGRASE; INTEGRASE INHIBITOR; PROTEIN; PROTEIN LEDGF; PROTEIN P75; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANISOTROPY; ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; COMPETITIVE INHIBITION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; FEMALE; HELA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR DOCKING; MOLECULAR MIMICRY; NUCLEAR MAGNETIC RESONANCE; PEPTIDE SYNTHESIS; PROTEIN ANALYSIS; PROTEIN STRUCTURE; VIRUS TITRATION;

AMINO ACID SEQUENCE; HELA CELLS; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV-1; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; PEPTIDES, CYCLIC; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 78249283226     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.09.046     Document Type: Article

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