Characterization and NMR solution structure of a novel cyclic pentapeptide inhibitor of pathogenic hantaviruses

Chemical Biology and Drug Design

Volumn 69, Issue 3, 2007, Pages 180-190

  Hall, Pamela R ^a   Malone, LaDonna ^a   Sillerud, Laurel O ^a   Ye, Chunyan ^a   Hjelle, Brian L ^a   Larson, Richard S ^a  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

Author keywords

Cyclic pentapeptide; Drug discovery; Hantavirus; Nuclear magnetic resonance; Viral inhibitor

Indexed keywords

AMINO ACID; ANTIVIRUS AGENT; BETA3 INTEGRIN; CYCLO(CYSTEINYLPROLYLPHENYLALANYLVALYLCYSTEINE); CYCLO(CYSTEINYLPROLYLPHENYLALANYLVALYLLYSYLTHREONYL GLUTAMINYLLEUCYLCYSTEINE); IMMUNOGLOBULIN F(AB) FRAGMENT; NONAPEPTIDE; PENTAPEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CERCOPITHECIDAE; CONTROLLED STUDY; DRUG BINDING; DRUG STRUCTURE; HANTAVIRUS; IC 50; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SIN NOMBRE VIRUS; STRUCTURE ANALYSIS; VIRUS INHIBITION;

AMINO ACID SEQUENCE; BINDING SITES; HANTAVIRUS; INHIBITORY CONCENTRATION 50; INTEGRINS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES, CYCLIC; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY;

HANTAVIRUS; SIN NOMBRE VIRUS;

EID: 34247245116     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2007.00489.x     Document Type: Article

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