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Volumn 8, Issue 8, 2016, Pages

Evidence to support the anti-cancer effect of olive leaf extract and future directions

Author keywords

Cyclooxygenase 2; Inflammation; Mediterranean diet; Oleuropein; Olive leaf; Oxidative stress

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CYCLOOXYGENASE 2; ESTROGEN RECEPTOR; EXTRA VIRGIN OLIVE OIL; FLAVONOID; HYDROXYTYROSOL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LUTEOLIN; MITOGEN ACTIVATED PROTEIN KINASE 3; OLEUROPEIN; PHYTOESTROGEN; POLYPHENOL; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR; ANTINEOPLASTIC AGENT; PLANT EXTRACT;

EID: 84983353747     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu8080513     Document Type: Review
Times cited : (150)

References (150)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D.; Weinberg, R.A. Hallmarks of cancer: The next generation. Cell 2011, 144, 646–674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 3
    • 84930021507 scopus 로고    scopus 로고
    • Mediterranean diet and risk of endometrial cancer: A pooled analysis of three Italian case-control studies
    • Filomeno, M.; Bosetti, C.; Bidoli, E.; Levi, F.; Serraino, D.; Montella, M.; La Vecchia, C.; Tavani, A. Mediterranean diet and risk of endometrial cancer: A pooled analysis of three Italian case-control studies. Br. J. Cancer 2015, 112, 1816–1821.
    • (2015) Br. J. Cancer , vol.112 , pp. 1816-1821
    • Filomeno, M.1    Bosetti, C.2    Bidoli, E.3    Levi, F.4    Serraino, D.5    Montella, M.6    La Vecchia, C.7    Tavani, A.8
  • 4
    • 85057640414 scopus 로고    scopus 로고
    • Does a Mediterranean-Type Diet Reduce Cancer Risk?
    • Schwingshackl, L.; Hoffmann, G. Does a Mediterranean-Type Diet Reduce Cancer Risk? Curr. Nutr. Rep. 2015, 5, 9–17.
    • (2015) Curr. Nutr. Rep. , vol.5 , pp. 9-17
    • Schwingshackl, L.1    Hoffmann, G.2
  • 7
    • 79961138403 scopus 로고    scopus 로고
    • Randomized, controlled nutrition education trial promotes a Mediterranean diet and improves anthropometric, dietary, and metabolic parameters in adults
    • Panunzio, M.F.; Caporizzi, R.; Antoniciello, A.; Cela, E.P.; Ferguson, L.R.; D’Ambrosio, P. Randomized, controlled nutrition education trial promotes a Mediterranean diet and improves anthropometric, dietary, and metabolic parameters in adults. Ann. Ig. Med. Prev. Comunità 2010, 23, 13–25.
    • (2010) Ann. Ig. Med. Prev. Comunità , vol.23 , pp. 13-25
    • Panunzio, M.F.1    Caporizzi, R.2    Antoniciello, A.3    Cela, E.P.4    Ferguson, L.R.5    D’Ambrosio, P.6
  • 10
    • 84983284795 scopus 로고    scopus 로고
    • The Mediterranean Diet between traditional foods and human health: The culinary example of Puglia (Southern Italy)
    • Renna, M.; Rinaldi, V.A.; Gonnella, M. The Mediterranean Diet between traditional foods and human health: The culinary example of Puglia (Southern Italy). Int. J. Gastron. Food Sci. 2015, 2, 63–71.
    • (2015) Int. J. Gastron. Food Sci. , vol.2 , pp. 63-71
    • Renna, M.1    Rinaldi, V.A.2    Gonnella, M.3
  • 11
    • 84907934171 scopus 로고    scopus 로고
    • Monounsaturated fatty acids, olive oil and health status: A systematic review and meta-analysis of cohort studies
    • Schwingshackl, L.; Hoffmann, G. Monounsaturated fatty acids, olive oil and health status: A systematic review and meta-analysis of cohort studies. Lipids Health Dis. 2014, 13, 154.
    • (2014) Lipids Health Dis , vol.13 , pp. 154
    • Schwingshackl, L.1    Hoffmann, G.2
  • 12
    • 79960880713 scopus 로고    scopus 로고
    • Olive oil intake is inversely related to cancer prevalence: A systematic review and a meta-analysis of 13,800 patients and 23,340 controls in 19 observational studies
    • Psaltopoulou, T.; Kosti, R.I.; Haidopoulos, D.; Dimopoulos, M.; Panagiotakos, D.B. Olive oil intake is inversely related to cancer prevalence: A systematic review and a meta-analysis of 13,800 patients and 23,340 controls in 19 observational studies. Lipids Health Dis. 2011, 10, 127.
    • (2011) Lipids Health Dis , vol.10 , pp. 127
    • Psaltopoulou, T.1    Kosti, R.I.2    Haidopoulos, D.3    Dimopoulos, M.4    Panagiotakos, D.B.5
  • 13
    • 84979702324 scopus 로고    scopus 로고
    • Geographical discrimination of extra-virgin olive oils from the Italian coasts by combining stable isotope data and carotenoid content within a multivariate analysis
    • Portarena, S.; Baldacchini, C.; Brugnoli, E. Geographical discrimination of extra-virgin olive oils from the Italian coasts by combining stable isotope data and carotenoid content within a multivariate analysis. Food Chem. 2017, 215, 1–6.
    • (2017) Food Chem , vol.215 , pp. 1-6
    • Portarena, S.1    Baldacchini, C.2    Brugnoli, E.3
  • 14
    • 85007323719 scopus 로고    scopus 로고
    • Changes in chemical and sensory characteristics of Chemlali extra-virgin olive oil as depending on filtration
    • Jabeur, H.; Zribi, A.; Bouaziz, M. Changes in chemical and sensory characteristics of Chemlali extra-virgin olive oil as depending on filtration. Eur. J. Lipid Sci. Technol. 2016.
    • (2016) Eur. J. Lipid Sci. Technol
    • Jabeur, H.1    Zribi, A.2    Bouaziz, M.3
  • 15
    • 85022093502 scopus 로고    scopus 로고
    • Springer Science & Business Media, (accessed on 8 March 2016)
    • Aparicio, R.; Harwood, J. Handbook of Olive Oil: Analysis and Properties. Springer Science & Business Media, 2013. Available online: https://books.google.com/books?hl=en&lr=&id=gQrkBwAAQBAJ&pgis=1 (accessed on 8 March 2016).
    • (2013) Handbook of Olive Oil: Analysis and Properties
    • Aparicio, R.1    Harwood, J.2
  • 16
    • 84855530450 scopus 로고    scopus 로고
    • Scientific Opinion on the Substantiation of health Claims Related to Polyphenols in Olive and Protection of LDL Particles from Oxidative damage (ID 1333, 1638, 1639, 1696, 2865), Maintenance of Normal Blood HDL Cholesterol Concentrations (ID 1639), Mainte
    • EFSA Panel on Dietetic Products, N. and A. (NDA). Scientific Opinion on the Substantiation of health Claims Related to Polyphenols in Olive and Protection of LDL Particles from Oxidative damage (ID 1333, 1638, 1639, 1696, 2865), Maintenance of Normal Blood HDL Cholesterol Concentrations (ID 1639), Mainte. EFSA J. 2011 2011, 9.
    • (2011) EFSA J , vol.2011
  • 19
    • 85013623979 scopus 로고    scopus 로고
    • Olive leaf phenolics and cardiovascular risk reduction: Physiological effects and mechanisms of action
    • Lockyer, S.; Yaqoob, P.; Spencer, J.P.E.; Rowland, I. Olive leaf phenolics and cardiovascular risk reduction: Physiological effects and mechanisms of action. Nutr. Aging 2012, 1, 125–140.
    • (2012) Nutr. Aging , vol.1 , pp. 125-140
    • Lockyer, S.1    Yaqoob, P.2    Spencer, J.P.E.3    Rowland, I.4
  • 20
    • 74949115310 scopus 로고    scopus 로고
    • Olive tree (Olea europaea) leaves: Potential beneficial effects on human health
    • El, S.N.; Karakaya, S. Olive tree (Olea europaea) leaves: Potential beneficial effects on human health. Nutr. Rev. 2009, 67, 632–638.
    • (2009) Nutr. Rev. , vol.67 , pp. 632-638
    • El, S.N.1    Karakaya, S.2
  • 21
    • 0003905217 scopus 로고
    • (accessed on 21 October 2015)
    • Wren, R. Potter’s New Cyclopaedia of Botanical Drugs and Preparations. 1994. Available online: https://scholar.google.co.nz/scholar?hl=en&q=R.C.+Wren+%28Ed.%29%2C+Potter%27s+New+Cyclopaedia+of+Botanical+Drugs+and+Preparations%2C+The+C.W.+Daniel%2C+Essex%2C+UK+%281994%29%2C+p.+20&btnG=&as_sdt=1%2C5&as_sdtp=#0 (accessed on 21 October 2015).
    • (1994) Potter’s New Cyclopaedia of Botanical Drugs and Preparations
    • Wren, R.1
  • 23
    • 84925063946 scopus 로고    scopus 로고
    • Differences in n-alkane profiles between olives and olive leaves as potential indicators for the assessment of olive leaf presence in virgin olive oils
    • Mihailova, A.; Abbado, D.; Pedentchouk, N. Differences in n-alkane profiles between olives and olive leaves as potential indicators for the assessment of olive leaf presence in virgin olive oils. Eur. J. Lipid Sci. Technol. 2015, 117, 1480–1485.
    • (2015) Eur. J. Lipid Sci. Technol. , vol.117 , pp. 1480-1485
    • Mihailova, A.1    Abbado, D.2    Pedentchouk, N.3
  • 25
    • 84871729357 scopus 로고    scopus 로고
    • Luteolin inhibits human prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis
    • Pratheeshkumar, P.; Son, Y.-O.; Budhraja, A.; Wang, X.; Ding, S.; Wang, L.; Hitron, A.; Lee, J.-C.; Kim, D.; Divya, S.P. et al. Luteolin inhibits human prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis. PLoS ONE 2012, 7
    • (2012) Plos ONE , vol.7
    • Pratheeshkumar, P.1    Son, Y.-O.2    Budhraja, A.3    Wang, X.4    Ding, S.5    Wang, L.6    Hitron, A.7    Lee, J.-C.8    Kim, D.9    Divya, S.P.10
  • 26
    • 84860389460 scopus 로고    scopus 로고
    • Dietary flavones and flavonones display differential effects on aromatase (CYP19) transcription in the breast cancer cells MCF-7
    • Li, F.; Ye, L.; Lin, S.; Leung, L.K. Dietary flavones and flavonones display differential effects on aromatase (CYP19) transcription in the breast cancer cells MCF-7. Mol. Cell. Endocrinol. 2011, 344, 51–58.
    • (2011) Mol. Cell. Endocrinol. , vol.344 , pp. 51-58
    • Li, F.1    Ye, L.2    Lin, S.3    Leung, L.K.4
  • 27
    • 84862016307 scopus 로고    scopus 로고
    • Apigenin induces apoptosis via extrinsic pathway, inducing p53 and inhibiting STAT3 and NFκB signaling in HER2-overexpressing breast cancer cells
    • Seo, H.-S.; Choi, H.-S.; Kim, S.-R.; Choi, Y.K.; Woo, S.-M.; Shin, I.; Woo, J.-K.; Park, S.-Y.; Shin, Y.C.; Ko, S.-G. et al. Apigenin induces apoptosis via extrinsic pathway, inducing p53 and inhibiting STAT3 and NFκB signaling in HER2-overexpressing breast cancer cells. Mol. Cell. Biochem. 2012, 366, 319–334.
    • (2012) Mol. Cell. Biochem. , vol.366 , pp. 319-334
    • Seo, H.-S.1    Choi, H.-S.2    Kim, S.-R.3    Choi, Y.K.4    Woo, S.-M.5    Shin, I.6    Woo, J.-K.7    Park, S.-Y.8    Shin, Y.C.9    Ko, S.-G.10
  • 29
    • 84907043865 scopus 로고    scopus 로고
    • Regulation of GLUT transporters by flavonoids in androgen-sensitive and -insensitive prostate cancer cells
    • Gonzalez-Menendez, P.; Hevia, D.; Rodriguez-Garcia, A.; Mayo, J.C.; Sainz, R.M. Regulation of GLUT transporters by flavonoids in androgen-sensitive and -insensitive prostate cancer cells. Endocrinology 2014, 155, 3238–3250.
    • (2014) Endocrinology , vol.155 , pp. 3238-3250
    • Gonzalez-Menendez, P.1    Hevia, D.2    Rodriguez-Garcia, A.3    Mayo, J.C.4    Sainz, R.M.5
  • 30
    • 32944461793 scopus 로고    scopus 로고
    • Transfer of phenolic compounds during olive oil extraction in relation to ripening stage of the fruit
    • Artajo, L.S.; Romero, M.P.; Motilva, M.J. Transfer of phenolic compounds during olive oil extraction in relation to ripening stage of the fruit. J. Sci. Food Agric. 2006, 86, 518–527.
    • (2006) J. Sci. Food Agric. , vol.86 , pp. 518-527
    • Artajo, L.S.1    Romero, M.P.2    Motilva, M.J.3
  • 31
    • 41149151153 scopus 로고    scopus 로고
    • Liquid chromatography/triple quadrupole tandem mass spectrometry with multiple reaction monitoring for optimal selection of transitions to evaluate nutraceuticals from olive-tree materials
    • Luján, R.J.; Capote, F.P.; Marinas, A.; de Castro, M.D.L. Liquid chromatography/triple quadrupole tandem mass spectrometry with multiple reaction monitoring for optimal selection of transitions to evaluate nutraceuticals from olive-tree materials. Rapid Commun. Mass Spectrom. 2008, 22, 855–864.
    • (2008) Rapid Commun. Mass Spectrom. , vol.22 , pp. 855-864
    • Luján, R.J.1    Capote, F.P.2    Marinas, A.3    De Castro, M.D.L.4
  • 32
    • 84861574407 scopus 로고    scopus 로고
    • Analysis of phenolic compounds in olive oil by solid-phase extraction and ultra high performance liquid chromatography-tandem mass spectrometry
    • Flores, A.; Isabel, M.; Romero-González, R.; Frenich, G.; Vidal, A.; Martínez, L.J. Analysis of phenolic compounds in olive oil by solid-phase extraction and ultra high performance liquid chromatography-tandem mass spectrometry. Food Chem. 2012, 134, 2465–2472.
    • (2012) Food Chem , vol.134 , pp. 2465-2472
    • Flores, A.1    Isabel, M.2    Romero-González, R.3    Frenich, G.4    Vidal, A.5    Martínez, L.J.6
  • 33
    • 84928686668 scopus 로고    scopus 로고
    • Phytochemicals and Other Characteristics of Croatian Monovarietal Extra Virgin Olive Oils from Oblica, Lastovka and Levantinka Varieties
    • Šarolić, M.; Gugić, M.; Friganović, E.; Tuberoso, C.; Jerković, I. Phytochemicals and Other Characteristics of Croatian Monovarietal Extra Virgin Olive Oils from Oblica, Lastovka and Levantinka Varieties. Molecules 2015, 20, 4395–4409.
    • (2015) Molecules , vol.20 , pp. 4395-4409
    • Šarolić, M.1    Gugić, M.2    Friganović, E.3    Tuberoso, C.4    Jerković, I.5
  • 34
    • 84873096468 scopus 로고    scopus 로고
    • Characterisation and phenolic profiles of two rare olive oils from southern Tunisia: Dhokar and Gemri-Dhokar cultivars
    • Rigane, G.; Ayadi, M.; Boukhris, M.; Sayadi, S.; Bouaziz, M. Characterisation and phenolic profiles of two rare olive oils from southern Tunisia: Dhokar and Gemri-Dhokar cultivars. J. Sci. Food Agric. 2013, 93, 527–534.
    • (2013) J. Sci. Food Agric. , vol.93 , pp. 527-534
    • Rigane, G.1    Ayadi, M.2    Boukhris, M.3    Sayadi, S.4    Bouaziz, M.5
  • 36
    • 79952538862 scopus 로고    scopus 로고
    • Gamma irradiation of air-dried olive leaves: Effective decontamination and impact on the antioxidative properties and on phenolic compounds
    • Aouidi, F.; Ayari, S.; Ferhi, H.; Roussos, S.; Hamdi, M. Gamma irradiation of air-dried olive leaves: Effective decontamination and impact on the antioxidative properties and on phenolic compounds. Food Chem. 2011, 127, 1105–1113.
    • (2011) Food Chem , vol.127 , pp. 1105-1113
    • Aouidi, F.1    Ayari, S.2    Ferhi, H.3    Roussos, S.4    Hamdi, M.5
  • 37
    • 32044473083 scopus 로고    scopus 로고
    • Dynamic ultrasound-assisted extraction of oleuropein and related biophenols from olive leaves
    • Japón-Luján, L.; Luque-Rodríguez, J.; Luque de Castro, M. Dynamic ultrasound-assisted extraction of oleuropein and related biophenols from olive leaves. J. Chromatogr. A 2006, 1108, 76–82.
    • (2006) J. Chromatogr. A , vol.1108 , pp. 76-82
    • Japón-Luján, L.1    Luque-Rodríguez, J.2    Luque De Castro, M.3
  • 38
    • 42449128849 scopus 로고    scopus 로고
    • Liquid-liquid extraction for the enrichment of edible oils with phenols from olive leaf extracts
    • Japón-Luján, R.; Luque de Castro, M.D. Liquid-liquid extraction for the enrichment of edible oils with phenols from olive leaf extracts. J. Agric. Food Chem. 2008, 56, 2505–2511.
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 2505-2511
    • Japón-Luján, R.1    Luque De Castro, M.D.2
  • 39
    • 84920035776 scopus 로고    scopus 로고
    • Consumption of extra-virgin olive oil rich in phenolic compounds has beneficial antioxidant effects in healthy human adults
    • Oliveras-López, M.-J.; Berná, G.; Jurado-Ruiz, E.; López-García de la Serrana, H.; Martín, F. Consumption of extra-virgin olive oil rich in phenolic compounds has beneficial antioxidant effects in healthy human adults. J. Funct. Foods 2014, 10, 475–484.
    • (2014) J. Funct. Foods , vol.10 , pp. 475-484
    • Oliveras-López, M.-J.1    Berná, G.2    Jurado-Ruiz, E.3
  • 40
    • 84892444415 scopus 로고    scopus 로고
    • Effect of olive oil phenols on the production of inflammatory mediators in freshly isolated human monocytes
    • Rosignoli, P.; Fuccelli, R.; Fabiani, R.; Servili, M.; Morozzi, G. Effect of olive oil phenols on the production of inflammatory mediators in freshly isolated human monocytes. J. Nutr. Biochem. 2013, 24, 1513–1519.
    • (2013) J. Nutr. Biochem. , vol.24 , pp. 1513-1519
    • Rosignoli, P.1    Fuccelli, R.2    Fabiani, R.3    Servili, M.4    Morozzi, G.5
  • 41
    • 85020605288 scopus 로고    scopus 로고
    • Impact of phenolic-rich olive leaf extract on blood pressure, plasma lipids and inflammatory markers: A randomised controlled trial
    • Lockyer, S.; Rowland, I.; Spencer, J.P.E.; Yaqoob, P.; Stonehouse, W. Impact of phenolic-rich olive leaf extract on blood pressure, plasma lipids and inflammatory markers: A randomised controlled trial. Eur. J. Nutr. 2016.
    • (2016) Eur. J. Nutr
    • Lockyer, S.1    Rowland, I.2    Spencer, J.P.E.3    Yaqoob, P.4    Stonehouse, W.5
  • 43
    • 22744447495 scopus 로고    scopus 로고
    • Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor
    • Hamdi, H.K.; Castellon, R. Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor. Biochem. Biophys. Res. Commun. 2005, 334, 769–778.
    • (2005) Biochem. Biophys. Res. Commun. , vol.334 , pp. 769-778
    • Hamdi, H.K.1    Castellon, R.2
  • 45
    • 84938614608 scopus 로고    scopus 로고
    • Phytochemical Properties and Anti-Proliferative Activity of Olea europaea L. Leaf Extracts against Pancreatic Cancer Cells
    • Goldsmith, C.D.; Vuong, Q.V.; Sadeqzadeh, E.; Stathopoulos, C.E.; Roach, P.D.; Scarlett, C.J. Phytochemical Properties and Anti-Proliferative Activity of Olea europaea L. Leaf Extracts against Pancreatic Cancer Cells. Molecules 2015, 20, 12992–3004.
    • (2015) Molecules , vol.20 , pp. 12992-13004
    • Goldsmith, C.D.1    Vuong, Q.V.2    Sadeqzadeh, E.3    Stathopoulos, C.E.4    Roach, P.D.5    Scarlett, C.J.6
  • 46
    • 84899998513 scopus 로고    scopus 로고
    • Olive (Olea europaea) Leaf Extract Induces Apoptosis and Monocyte/Macrophage Differentiation in Human Chronic Myelogenous Leukemia K562 Cells: Insight into the Underlying Mechanism
    • Samet, I.; Han, J.; Jlaiel, L.; Sayadi, S.; Isoda, H. Olive (Olea europaea) Leaf Extract Induces Apoptosis and Monocyte/Macrophage Differentiation in Human Chronic Myelogenous Leukemia K562 Cells: Insight into the Underlying Mechanism. Oxid. Med. Cell. Longev. 2014, 2014, 927619.
    • (2014) Oxid. Med. Cell. Longev , vol.2014
    • Samet, I.1    Han, J.2    Jlaiel, L.3    Sayadi, S.4    Isoda, H.5
  • 51
    • 84888121068 scopus 로고    scopus 로고
    • Hydroxytyrosol promotes superoxide production and defects in autophagy leading to anti-proliferation and apoptosis on human prostate cancer cells
    • Luo, C.; Li, Y.; Wang, H.; Cui, Y.; Feng, Z.; Li, H.; Li, Y.; Wang, Y.; Wurtz, K.; Weber, P. et al. Hydroxytyrosol promotes superoxide production and defects in autophagy leading to anti-proliferation and apoptosis on human prostate cancer cells. Curr. Cancer Drug Targets 2013, 13, 625–639.
    • (2013) Curr. Cancer Drug Targets , vol.13 , pp. 625-639
    • Luo, C.1    Li, Y.2    Wang, H.3    Cui, Y.4    Feng, Z.5    Li, H.6    Li, Y.7    Wang, Y.8    Wurtz, K.9    Weber, P.10
  • 52
    • 77950897188 scopus 로고    scopus 로고
    • Review of thin layer drying of foods: Theory, modeling, and experimental results
    • Erbay, Z.; Icier, F. A review of thin layer drying of foods: Theory, modeling, and experimental results. Crit. Rev. Food Sci. Nutr. 2010, 50, 441–464.
    • (2010) Crit. Rev. Food Sci. Nutr. , vol.50 , pp. 441-464
    • Erbay, Z.1    Icier, F.A.2
  • 53
    • 77953474824 scopus 로고    scopus 로고
    • Plant polyphenols as dietary antioxidants in human health and disease
    • Pandey, K.; Rizvi, S. Plant polyphenols as dietary antioxidants in human health and disease. Oxid. Med. Cell. Longev. 2009, 2, 270–278.
    • (2009) Oxid. Med. Cell. Longev. , vol.2 , pp. 270-278
    • Pandey, K.1    Rizvi, S.2
  • 54
    • 84874848268 scopus 로고    scopus 로고
    • Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: A randomized, placebo-controlled, crossover trial
    • de Bock, M.; Derraik, J.G.B.; Brennan, C.M.; Biggs, J.B.; Morgan, P.E.; Hodgkinson, S.C.; Hofman, P.L.; Cutfield, W.S. Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: A randomized, placebo-controlled, crossover trial. PLoS ONE 2013, 8, e57622.
    • (2013) Plos ONE , vol.8
    • De Bock, M.1    Derraik, J.G.B.2    Brennan, C.M.3    Biggs, J.B.4    Morgan, P.E.5    Hodgkinson, S.C.6    Hofman, P.L.7    Cutfield, W.S.8
  • 55
    • 70349934718 scopus 로고    scopus 로고
    • Antidiabetic and antioxidant effects of hydroxytyrosol and oleuropein from olive leaves in alloxan-diabetic rats
    • Jemai, H.; El Feki, A.; Sayadi, S. Antidiabetic and antioxidant effects of hydroxytyrosol and oleuropein from olive leaves in alloxan-diabetic rats. J. Agric. Food Chem. 2009, 57, 8798–8804.
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 8798-8804
    • Jemai, H.1    El Feki, A.2    Sayadi, S.3
  • 56
    • 84922699888 scopus 로고    scopus 로고
    • Oleuropein attenuates visceral adiposity in high-fat diet-induced obese mice through the modulation of WNT10b- and galanin-mediated signalings
    • Kuem, N.; Song, S.J.; Yu, R.; Yun, J.W.; Park, T. Oleuropein attenuates visceral adiposity in high-fat diet-induced obese mice through the modulation of WNT10b- and galanin-mediated signalings. Mol. Nutr. Food Res. 2014, 58, 2166–2176.
    • (2014) Mol. Nutr. Food Res. , vol.58 , pp. 2166-2176
    • Kuem, N.1    Song, S.J.2    Yu, R.3    Yun, J.W.4    Park, T.5
  • 57
    • 34548444575 scopus 로고    scopus 로고
    • Phenolic Molecules in Virgin Olive Oils: A Survey of Their Sensory Properties, Health Effects, Antioxidant Activity and Analytical Methods. An Overview of the Last Decade Alessandra
    • Bendini, A.; Cerretani, L.; Carrasco-Pancorbo, A.; Gómez-Caravaca, A.M.; Segura-Carretero, A.; Fernández-Gutiérrez, A.; Lercker, G. Phenolic Molecules in Virgin Olive Oils: A Survey of Their Sensory Properties, Health Effects, Antioxidant Activity and Analytical Methods. An Overview of the Last Decade Alessandra. Molecules 2007, 12, 1679–1719.
    • (2007) Molecules , vol.12 , pp. 1679-1719
    • Bendini, A.1    Cerretani, L.2    Carrasco-Pancorbo, A.3    Gómez-Caravaca, A.M.4    Segura-Carretero, A.5    Fernández-Gutiérrez, A.6    Lercker, G.7
  • 58
    • 84905573472 scopus 로고    scopus 로고
    • Oleuropein offers cardioprotection in rats with simultaneous type 2 diabetes and renal hypertension
    • Nekooeian, A.A.; Khalili, A.; Khosravi, M.B. Oleuropein offers cardioprotection in rats with simultaneous type 2 diabetes and renal hypertension. Indian J. Pharmacol. 2015, 46, 398–403.
    • (2015) Indian J. Pharmacol. , vol.46 , pp. 398-403
    • Nekooeian, A.A.1    Khalili, A.2    Khosravi, M.B.3
  • 59
    • 76049105413 scopus 로고    scopus 로고
    • Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract
    • Lee, O.-H.; Lee, B.-Y. Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract. Bioresour. Technol. 2010, 101, 3751–3754.
    • (2010) Bioresour. Technol. , vol.101 , pp. 3751-3754
    • Lee, O.-H.1    Lee, B.-Y.2
  • 60
    • 84926651602 scopus 로고    scopus 로고
    • Leishmanicidal and apoptotic activities of oleuropein on Leishmania major
    • Elamin, M.H.; Al-Maliki, S.S. Leishmanicidal and apoptotic activities of oleuropein on Leishmania major. Int. J. Clin. Pharmacol. Ther. 2014, 52, 880–888.
    • (2014) Int. J. Clin. Pharmacol. Ther. , vol.52 , pp. 880-888
    • Elamin, M.H.1    Al-Maliki, S.S.2
  • 61
    • 84873725317 scopus 로고    scopus 로고
    • Secoiridoid derived from olive tree, inhibits the proliferation of human colorectal cancer cell through downregulation of HIF-1α
    • Cárdeno, A.; Sánchez-Hidalgo, M.; Rosillo, M.A.; Alarcón de la Lastra, C. Oleuropein, a secoiridoid derived from olive tree, inhibits the proliferation of human colorectal cancer cell through downregulation of HIF-1α. Nutr. Cancer 2013, 65, 147–156.
    • (2013) Nutr. Cancer , vol.65 , pp. 147-156
    • Cárdeno, A.1    Sánchez-Hidalgo, M.2    Rosillo, M.A.3    Lastra, A.D.L.4    Oleuropein, C.5
  • 63
    • 67349201394 scopus 로고    scopus 로고
    • Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells
    • Han, J.; Talorete, T.P.N.; Yamada, P.; Isoda, H. Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells. Cytotechnology 2009, 59, 45–53.
    • (2009) Cytotechnology , vol.59 , pp. 45-53
    • Han, J.1    Talorete, T.P.N.2    Yamada, P.3    Isoda, H.4
  • 65
    • 84926254927 scopus 로고    scopus 로고
    • Verbascoside—A review of its occurrence, (Bio) synthesis and pharmacological significance
    • Alipieva, K.; Korkina, L.; Orhan, I.E.; Georgiev, M.I. Verbascoside—A review of its occurrence, (bio) synthesis and pharmacological significance. Biotechnol. Adv. 2014, 32, 1065–1076.
    • (2014) Biotechnol. Adv. , vol.32 , pp. 1065-1076
    • Alipieva, K.1    Korkina, L.2    Orhan, I.E.3    Georgiev, M.I.4
  • 66
    • 84983238216 scopus 로고    scopus 로고
    • Effect of Geographical Region and Harvesting Date on Antioxidant Activity, Phenolic and Flavonoid Content of Olive Leaves
    • Al-Rimawi, F.; Odeh, I.; Bisher, A.; Abbadi, J.; Qabbajeh, M. Effect of Geographical Region and Harvesting Date on Antioxidant Activity, Phenolic and Flavonoid Content of Olive Leaves. J. Food Nutr. Res. 2014, 2, 925–930.
    • (2014) J. Food Nutr. Res. , vol.2 , pp. 925-930
    • Al-Rimawi, F.1    Odeh, I.2    Bisher, A.3    Abbadi, J.4    Qabbajeh, M.5
  • 67
    • 71749121785 scopus 로고    scopus 로고
    • Luteolin, a food-derived flavonoid, suppresses adipocyte-dependent activation of macrophages by inhibiting JNK activation
    • Ando, C.; Takahashi, N.; Hirai, S.; Nishimura, K.; Lin, S.; Uemura, T.; Goto, T.; Yu, R.; Nakagami, J.; Murakami, S. et al. Luteolin, a food-derived flavonoid, suppresses adipocyte-dependent activation of macrophages by inhibiting JNK activation. FEBS Lett. 2009, 583, 3649–3654.
    • (2009) FEBS Lett , vol.583 , pp. 3649-3654
    • Ando, C.1    Takahashi, N.2    Hirai, S.3    Nishimura, K.4    Lin, S.5    Uemura, T.6    Goto, T.7    Yu, R.8    Nakagami, J.9    Murakami, S.10
  • 68
    • 77953189137 scopus 로고    scopus 로고
    • Apigenin: A promising molecule for cancer prevention
    • Shukla, S.; Gupta, S. Apigenin: A promising molecule for cancer prevention. Pharm. Res. 2010, 27, 962–978.
    • (2010) Pharm. Res. , vol.27 , pp. 962-978
    • Shukla, S.1    Gupta, S.2
  • 69
    • 1342333578 scopus 로고    scopus 로고
    • Supplementation of oils with oleanolic acid from the olive leaf (Olea europaea)
    • Guinda, Á.; Pérez-Camino, M.C.; Lanzón, A. Supplementation of oils with oleanolic acid from the olive leaf (Olea europaea). Eur. J. Lipid Sci. Technol. 2004, 106, 22–26.
    • (2004) Eur. J. Lipid Sci. Technol. , vol.106 , pp. 22-26
    • Guinda, Á.1    Pérez-Camino, M.C.2    Lanzón, A.3
  • 70
    • 3242776040 scopus 로고    scopus 로고
    • Countercurrent supercritical fluid extraction and fractionation of high-added-value compounds from a hexane extract of olive leaves
    • Tabera, J.; Guinda, A.; Ruiz-Rodríguez, A.; Señoráns, F.J.; Ibáñez, E.; Albi, T.; Reglero, G. Countercurrent supercritical fluid extraction and fractionation of high-added-value compounds from a hexane extract of olive leaves. J. Agric. Food Chem. 2004, 52, 4774–4779.
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 4774-4779
    • Tabera, J.1    Guinda, A.2    Ruiz-Rodríguez, A.3    Señoráns, F.J.4    Ibáñez, E.5    Albi, T.6    Reglero, G.7
  • 71
    • 84898944940 scopus 로고    scopus 로고
    • Effects of α-tocopherol and β-carotene supplementation on cancer incidence and mortality: 18-year postintervention follow-up of the Alpha-tocopherol, Beta-carotene Cancer Prevention Study
    • Virtamo, J.; Taylor, P.R.; Kontto, J.; Männistö, S.; Utriainen, M.; Weinstein, S.J.; Huttunen, J.; Albanes, D. Effects of α-tocopherol and β-carotene supplementation on cancer incidence and mortality: 18-year postintervention follow-up of the Alpha-tocopherol, Beta-carotene Cancer Prevention Study. Int. J. Cancer 2014, 135, 178–185.
    • (2014) Int. J. Cancer , vol.135 , pp. 178-185
    • Virtamo, J.1    Taylor, P.R.2    Kontto, J.3    Männistö, S.4    Utriainen, M.5    Weinstein, S.J.6    Huttunen, J.7    Albanes, D.8
  • 72
    • 84874627322 scopus 로고    scopus 로고
    • Fernández-Arroyo, S.; et al. Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: A new family of gerosuppressant agents
    • Menendez, J.A.; Joven, J.; Aragonès, G.; Barrajón-Catalán, E.; Beltrán-Debón, R.; Borrás-Linares, I.; Camps, J.; Corominas-Faja, B.; Cufí, S.; Fernández-Arroyo, S.; et al. Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: A new family of gerosuppressant agents. Cell Cycle 2013, 12, 555–578.
    • (2013) Cell Cycle , vol.12 , pp. 555-578
    • Menendez, J.A.1    Joven, J.2    Aragonès, G.3    Barrajón-Catalán, E.4    Beltrán-Debón, R.5    Borrás-Linares, I.6    Camps, J.7    Corominas-Faja, B.8    Cufí, S.9
  • 73
    • 84893527967 scopus 로고    scopus 로고
    • Polyphenols and the modulation of gene expression pathways: Can we eat our way out of the danger of chronic disease?
    • Joven, J.; Micol, V.; Segura-Carretero, A.; Alonso-Villaverde, C.; Menéndez, J.A. Polyphenols and the modulation of gene expression pathways: Can we eat our way out of the danger of chronic disease? Crit. Rev. Food Sci. Nutr. 2014, 54, 985–1001.
    • (2014) Crit. Rev. Food Sci. Nutr. , vol.54 , pp. 985-1001
    • Joven, J.1    Micol, V.2    Segura-Carretero, A.3    Alonso-Villaverde, C.4    Menéndez, J.A.5
  • 74
    • 84892366653 scopus 로고    scopus 로고
    • The search for a new paradigm to study micronutrient and phytochemical bioavailability: From reductionism to holism
    • Fardet, A.; Rock, E. The search for a new paradigm to study micronutrient and phytochemical bioavailability: From reductionism to holism. Med. Hypotheses. 2014, 82, 181–186.
    • (2014) Med. Hypotheses. , vol.82 , pp. 181-186
    • Fardet, A.1    Rock, E.2
  • 75
    • 84935468336 scopus 로고    scopus 로고
    • Antioxidant Activity and Chemical Components as Potential Anticancer Agents in the Olive Leaf (Olea europaea L. cv Leccino.) Decoction
    • De Marino, S.; Festa, C.; Zollo, F.; Nini, A.; Antenucci, L.; Raimo, G.; Iorizzi, M. Antioxidant Activity and Chemical Components as Potential Anticancer Agents in the Olive Leaf (Olea europaea L. cv Leccino.) Decoction. Anticancer. Agents Med. Chem. 2014, 14, 1376–1385.
    • (2014) Anticancer. Agents Med. Chem. , vol.14 , pp. 1376-1385
    • De Marino, S.1    Festa, C.2    Zollo, F.3    Nini, A.4    Antenucci, L.5    Raimo, G.6    Iorizzi, M.7
  • 76
    • 0033991129 scopus 로고    scopus 로고
    • Antioxidant activity of phenolics extracted from Olea europaea L. Leaves
    • Benavente-garcia, O.; Castillo, J.; Lorente, J.; Ortun, A. Antioxidant activity of phenolics extracted from Olea europaea L. leaves. Food Chem. 2000, 68, 457–462.
    • (2000) Food Chem , vol.68 , pp. 457-462
    • Benavente-Garcia, O.1    Castillo, J.2    Lorente, J.3    Ortun, A.4
  • 77
    • 84866522871 scopus 로고    scopus 로고
    • Application of in vitro bioaccessibility and bioavailability methods for calcium, carotenoids, folate, iron, magnesium, polyphenols, zinc, and vitamins B6, B12, D, and E
    • Etcheverry, E.P.; Grusak, M.A.; Fleige, L.E. Application of in vitro bioaccessibility and bioavailability methods for calcium, carotenoids, folate, iron, magnesium, polyphenols, zinc, and vitamins B6, B12, D, and E. Front. Physiol. 2012, 3, 317.
    • (2012) Front. Physiol. , vol.3
    • Etcheverry, E.P.1    Grusak, M.A.2    Fleige, L.E.3
  • 79
    • 84886778658 scopus 로고    scopus 로고
    • Human absorption and metabolism of oleuropein and hydroxytyrosol ingested as olive (Olea europaea L.) leaf extract
    • De Bock, M.; Thorstensen, E.B.; Derraik, J.G.B.; Henderson, H.V.; Hofman, P.L.; Cutfield, W.S. Human absorption and metabolism of oleuropein and hydroxytyrosol ingested as olive (Olea europaea L.) leaf extract. Mol. Nutr. Food Res. 2013, 57, 2079–2085.
    • (2013) Mol. Nutr. Food Res. , vol.57 , pp. 2079-2085
    • De Bock, M.1    Thorstensen, E.B.2    Derraik, J.G.B.3    Henderson, H.V.4    Hofman, P.L.5    Cutfield, W.S.6
  • 80
    • 84859198349 scopus 로고    scopus 로고
    • Distribution of olive oil phenolic compounds in rat tissues after administration of a phenolic extract from olive cake
    • Serra, A.; Rubió, L.; Borràs, X.; Macià, A.; Romero, M.-P.; Motilva, M.-J. Distribution of olive oil phenolic compounds in rat tissues after administration of a phenolic extract from olive cake. Mol. Nutr. Food Res. 2012, 56, 486–496.
    • (2012) Mol. Nutr. Food Res. , vol.56 , pp. 486-496
    • Serra, A.1    Rubió, L.2    Borràs, X.3    Macià, A.4    Romero, M.-P.5    Motilva, M.-J.6
  • 81
    • 80052713514 scopus 로고    scopus 로고
    • Randomized controlled study of the urinary excretion of biophenols following acute and chronic intake of olive leaf supplements
    • Kendall, M.; Batterham, M.; Callahan, D.L.; Jardine, D.; Prenzler, P.D.; Robards, K.; Ryan, D. Randomized controlled study of the urinary excretion of biophenols following acute and chronic intake of olive leaf supplements. Food Chem. 2012, 130, 651–659.
    • (2012) Food Chem , vol.130 , pp. 651-659
    • Kendall, M.1    Batterham, M.2    Callahan, D.L.3    Jardine, D.4    Prenzler, P.D.5    Robards, K.6    Ryan, D.7
  • 83
    • 33744794936 scopus 로고    scopus 로고
    • The fate of olive oil polyphenols in the gastrointestinal tract: Implications of gastric and colonic microflora-dependent biotransformation
    • Corona, G.; Tzounis, X.; Assunta Dess, M.; Deiana, M.; Debnam, E.S.; Visioli, F.; Spencer, J.P.E. The fate of olive oil polyphenols in the gastrointestinal tract: Implications of gastric and colonic microflora-dependent biotransformation. Free Radic. Res. 2006, 40, 647–658.
    • (2006) Free Radic. Res. , vol.40 , pp. 647-658
    • Corona, G.1    Tzounis, X.2    Assunta Dess, M.3    Deiana, M.4    Debnam, E.S.5    Visioli, F.6    Spencer, J.7
  • 84
    • 35449005788 scopus 로고    scopus 로고
    • Study of the inhibitory activity of phenolic compounds found in olive products and their degradation by Lactobacillus plantarum strains
    • Landete, J.M.; Curiel, J.A.; Rodríguez, H.; de las Rivas, B.; Muñoz, R. Study of the inhibitory activity of phenolic compounds found in olive products and their degradation by Lactobacillus plantarum strains. Food Chem. 2008, 107, 320–326.
    • (2008) Food Chem , vol.107 , pp. 320-326
    • Landete, J.M.1    Curiel, J.A.2    Rodríguez, H.3    De Las Rivas, B.4    Muñoz, R.5
  • 85
    • 84907545939 scopus 로고    scopus 로고
    • Endogenous enzymes involved in the transformation of oleuropein in Spanish table olive varieties
    • Ramírez, E.; Medina, E.; Brenes, M.; Romero, C. Endogenous enzymes involved in the transformation of oleuropein in Spanish table olive varieties. J. Agric. Food Chem. 2014, 62, 9569–9575.
    • (2014) J. Agric. Food Chem. , vol.62 , pp. 9569-9575
    • Ramírez, E.1    Medina, E.2    Brenes, M.3    Romero, C.4
  • 86
    • 84919663432 scopus 로고    scopus 로고
    • Evidence of oleuropein degradation by olive leaf protein extract
    • De Leonardis, A.; Macciola, V.; Cuomo, F.; Lopez, F. Evidence of oleuropein degradation by olive leaf protein extract. Food Chem. 2015, 175, 568–574.
    • (2015) Food Chem , vol.175 , pp. 568-574
    • De Leonardis, A.1    Macciola, V.2    Cuomo, F.3    Lopez, F.4
  • 87
    • 84923274582 scopus 로고    scopus 로고
    • Enzymatic hydrolysis of oleuropein from Olea europea (Olive) leaf extract and antioxidant activities
    • Yuan, J.-J.; Wang, C.-Z.; Ye, J.-Z.; Tao, R.; Zhang, Y.-S. Enzymatic hydrolysis of oleuropein from Olea europea (olive) leaf extract and antioxidant activities. Molecules 2015, 20, 2903–2921.
    • (2015) Molecules , vol.20 , pp. 2903-2921
    • Yuan, J.-J.1    Wang, C.-Z.2    Ye, J.-Z.3    Tao, R.4    Zhang, Y.-S.5
  • 88
    • 84872478184 scopus 로고    scopus 로고
    • Expression of glucose transporters in cancers
    • Szablewski, L. Expression of glucose transporters in cancers. Biochim. Biophys. Acta 2013, 1835, 164–169.
    • (2013) Biochim. Biophys. Acta , vol.1835 , pp. 164-169
    • Szablewski, L.1
  • 91
    • 0035958709 scopus 로고    scopus 로고
    • Effects of virgin olive oil phenolics on scavenging of reactive nitrogen species and upon nitrergic neurotransmission
    • de la Puerta, R.; Domnı́guez, M.E.M.; Ruı́z-Gutı́errez, V.; Flavill, J.A.; Hoult, J.R.S. Effects of virgin olive oil phenolics on scavenging of reactive nitrogen species and upon nitrergic neurotransmission. Life Sci. 2001, 69, 1213–1222.
    • (2001) Life Sci , vol.69 , pp. 1213-1222
    • De La Puerta, R.1    Domn, M.E.M.2    Ruı́z-Gutı́errez, V.3    Flavill, J.A.4    Hoult, J.5
  • 92
    • 0032922781 scopus 로고    scopus 로고
    • Inhibition of leukocyte 5-lipoxygenase by phenolics from virgin olive oil
    • de la Puerta, R.; Ruiz Gutierrez, V.; Hoult, J.R. Inhibition of leukocyte 5-lipoxygenase by phenolics from virgin olive oil. Biochem. Pharmacol. 1999, 57, 445–449.
    • (1999) Biochem. Pharmacol , vol.57 , pp. 445-449
    • De La Puerta, R.1    Ruiz Gutierrez, V.2    Hoult, J.R.3
  • 93
    • 84892369382 scopus 로고    scopus 로고
    • How do nutritional antioxidants really work: Nucleophilic tone and para-hormesis versus free radical scavenging in vivo
    • Forman, H.J.; Davies, K.J.A.; Ursini, F. How do nutritional antioxidants really work: Nucleophilic tone and para-hormesis versus free radical scavenging in vivo. Free Radic. Biol. Med. 2014, 66, 24–35.
    • (2014) Free Radic. Biol. Med. , vol.66 , pp. 24-35
    • Forman, H.J.1    Davies, K.J.A.2    Ursini, F.3
  • 94
    • 84864010629 scopus 로고    scopus 로고
    • Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: Activation of Nrf2 and JNK-p62/SQSTM1 pathways
    • Zou, X.; Feng, Z.; Li, Y.; Wang, Y.; Wertz, K.; Weber, P.; Fu, Y.; Liu, J. Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: Activation of Nrf2 and JNK-p62/SQSTM1 pathways. J. Nutr. Biochem. 2012, 23, 994–1006.
    • (2012) J. Nutr. Biochem. , vol.23 , pp. 994-1006
    • Zou, X.1    Feng, Z.2    Li, Y.3    Wang, Y.4    Wertz, K.5    Weber, P.6    Fu, Y.7    Liu, J.8
  • 96
    • 79953713983 scopus 로고    scopus 로고
    • P-HPEA-EDA, a phenolic compound of virgin olive oil, activates AMP-activated protein kinase to inhibit carcinogenesis
    • Khanal, P.; Oh, W.-K.; Yun, H.J.; Namgoong, G.M.; Ahn, S.-G.; Kwon, S.-M.; Choi, H.-K.; Choi, H.S. p-HPEA-EDA, a phenolic compound of virgin olive oil, activates AMP-activated protein kinase to inhibit carcinogenesis. Carcinogenesis 2011, 32, 545–553.
    • (2011) Carcinogenesis , vol.32 , pp. 545-553
    • Khanal, P.1    Oh, W.-K.2    Yun, H.J.3    Namgoong, G.M.4    Ahn, S.-G.5    Kwon, S.-M.6    Choi, H.-K.7    Choi, H.S.8
  • 97
    • 79956133866 scopus 로고    scopus 로고
    • Hydroxytyrosol reduces intracellular reactive oxygen species levels in vascular endothelial cells by upregulating catalase expression through the AMPK-FOXO3a pathway
    • Zrelli, H.; Matsuoka, M.; Kitazaki, S.; Zarrouk, M.; Miyazaki, H. Hydroxytyrosol reduces intracellular reactive oxygen species levels in vascular endothelial cells by upregulating catalase expression through the AMPK-FOXO3a pathway. Eur. J. Pharmacol. 2011, 660, 275–282.
    • (2011) Eur. J. Pharmacol. , vol.660 , pp. 275-282
    • Zrelli, H.1    Matsuoka, M.2    Kitazaki, S.3    Zarrouk, M.4    Miyazaki, H.5
  • 99
    • 84883185036 scopus 로고    scopus 로고
    • Oleuropein and oleacein may restore biological functions of endothelial progenitor cells impaired by angiotensin II via activation of Nrf2/heme oxygenase-1 pathway
    • Parzonko, A.; Czerwińska, M.E.; Kiss, A.K.; Naruszewicz, M. Oleuropein and oleacein may restore biological functions of endothelial progenitor cells impaired by angiotensin II via activation of Nrf2/heme oxygenase-1 pathway. Phytomedicine 2013, 20, 1088–1094.
    • (2013) Phytomedicine , vol.20 , pp. 1088-1094
    • Parzonko, A.1    Czerwińska, M.E.2    Kiss, A.K.3    Naruszewicz, M.4
  • 103
    • 79955057132 scopus 로고    scopus 로고
    • The antioxidant and anti-proliferative activity of the Lebanese Olea europaea extract
    • Fares, R.; Bazzi, S.; Baydoun, S.E.; Abdel-Massih, R.M. The antioxidant and anti-proliferative activity of the Lebanese Olea europaea extract. Plant Foods Hum. Nutr. 2011, 66, 58–63.
    • (2011) Plant Foods Hum. Nutr. , vol.66 , pp. 58-63
    • Fares, R.1    Bazzi, S.2    Baydoun, S.E.3    Abdel-Massih, R.M.4
  • 104
    • 0035235716 scopus 로고    scopus 로고
    • Endogenous hormone metabolism as an exposure marker in breast cancer chemoprevention studies
    • Kaaks, R. Endogenous hormone metabolism as an exposure marker in breast cancer chemoprevention studies. IARC Sci. Publ. 2001, 154, 149–162.
    • (2001) IARC Sci. Publ. , vol.154 , pp. 149-162
    • Kaaks, R.1
  • 105
    • 0037123341 scopus 로고    scopus 로고
    • Endogenous Hormones and Breast Cancer Collaborative Group. Endogenous sex hormones and breast cancer in postmenopausal women: Reanalysis of nine prospective studies
    • Key, T.; Appleby, P.; Barnes, I.; Reeves, G. Endogenous Hormones and Breast Cancer Collaborative Group. Endogenous sex hormones and breast cancer in postmenopausal women: Reanalysis of nine prospective studies. J. Natl. Cancer Inst. 2002, 94, 606–616.
    • (2002) J. Natl. Cancer Inst. , vol.94 , pp. 606-616
    • Key, T.1    Appleby, P.2    Barnes, I.3    Reeves, G.4
  • 106
    • 79955033397 scopus 로고    scopus 로고
    • Estrogen receptor and progesterone receptor as predictive biomarkers of response to endocrine therapy: A prospectively powered pathology study in the Tamoxifen and Exemestane Adjuvant Multinational trial
    • Bartlett, J.M.S.; Brookes, C.L.; Robson, T.; van de Velde, C.J.H.; Billingham, L.J.; Campbell, F.M.; Grant, M.; Hasenburg, A.; Hille, E.T.M.; Kay, C. et al. Estrogen receptor and progesterone receptor as predictive biomarkers of response to endocrine therapy: A prospectively powered pathology study in the Tamoxifen and Exemestane Adjuvant Multinational trial. J. Clin. Oncol. 2011, 29, 1531–1538.
    • (2011) J. Clin. Oncol. , vol.29 , pp. 1531-1538
    • Bartlett, J.M.S.1    Brookes, C.L.2    Robson, T.3    Van De Velde, C.J.H.4    Billingham, L.J.5    Campbell, F.M.6    Grant, M.7    Hasenburg, A.8    Hille, E.T.M.9    Kay, C.10
  • 109
    • 47949120075 scopus 로고    scopus 로고
    • Sustained ERK activation is involved in the kaempferol-induced apoptosis of breast cancer cells and is more evident under 3-D culture condition
    • Kim, B.-W.; Lee, E.-R.; Min, H.-M.; Jeong, H.-S.; Ahn, J.-Y.; Kim, J.-H.; Choi, H.-Y.; Choi, H.; Kim, E.Y.; Park, S.P. et al. Sustained ERK activation is involved in the kaempferol-induced apoptosis of breast cancer cells and is more evident under 3-D culture condition. Cancer Biol. Ther. 2014, 7, 1080–1089.
    • (2014) Cancer Biol. Ther. , vol.7 , pp. 1080-1089
    • Kim, B.-W.1    Lee, E.-R.2    Min, H.-M.3    Jeong, H.-S.4    Ahn, J.-Y.5    Kim, J.-H.6    Choi, H.-Y.7    Choi, H.8    Kim, E.Y.9    Park, S.P.10
  • 110
    • 84899926820 scopus 로고    scopus 로고
    • Oleuropein inhibits tumour growth and metastases dissemination in ovariectomised nude mice with MCF-7 human breast tumour xenografts
    • Sepporta, M.V.; Fuccelli, R.; Rosignoli, P.; Ricci, G.; Servili, M.; Morozzi, G.; Fabiani, R. Oleuropein inhibits tumour growth and metastases dissemination in ovariectomised nude mice with MCF-7 human breast tumour xenografts. J. Funct. Foods. 2014, 8, 269–273.
    • (2014) J. Funct. Foods. , vol.8 , pp. 269-273
    • Sepporta, M.V.1    Fuccelli, R.2    Rosignoli, P.3    Ricci, G.4    Servili, M.5    Morozzi, G.6    Fabiani, R.7
  • 111
    • 84924680927 scopus 로고    scopus 로고
    • The Effects of Olive Leaf Extract on Antioxidant Enzymes Activity and Tumor Growth in Breast Cancer
    • Milanizadeh, S.; Bigdeli, M.R.; Rasoulian, B.; Amani, D. The Effects of Olive Leaf Extract on Antioxidant Enzymes Activity and Tumor Growth in Breast Cancer. Thrita 2014, 3.
    • (2014) Thrita , vol.3
    • Milanizadeh, S.1    Bigdeli, M.R.2    Rasoulian, B.3    Amani, D.4
  • 112
    • 14544303729 scopus 로고    scopus 로고
    • Aromatase inhibitors: Rationale and use in breast cancer
    • Osborne, C.; Tripathy, D. Aromatase inhibitors: Rationale and use in breast cancer. Annu. Rev. Med. 2005, 56, 103–116.
    • (2005) Annu. Rev. Med. , vol.56 , pp. 103-116
    • Osborne, C.1    Tripathy, D.2
  • 113
    • 84896489393 scopus 로고    scopus 로고
    • Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): An international, double-blind, randomised placebo-controlled trial
    • Cuzick, J.; Sestak, I.; Forbes, J.F.; Dowsett, M.; Knox, J.; Cawthorn, S.; Saunders, C.; Roche, N.; Mansel, R.E.; von Minckwitz, G.; et al. Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): An international, double-blind, randomised placebo-controlled trial. Lancet 2014, 383, 1041–1048.
    • (2014) Lancet , vol.383 , pp. 1041-1048
    • Cuzick, J.1    Sestak, I.2    Forbes, J.F.3    Dowsett, M.4    Knox, J.5    Cawthorn, S.6    Saunders, C.7    Roche, N.8    Mansel, R.E.9    Von Minckwitz, G.10
  • 114
    • 56949100154 scopus 로고    scopus 로고
    • Influence of food polyphenols on aryl hydrocarbon receptor-signaling pathway estimated by in vitro bioassay
    • Amakura, Y.; Tsutsumi, T.; Sasaki, K.; Nakamura, M.; Yoshida, T.; Maitani, T. Influence of food polyphenols on aryl hydrocarbon receptor-signaling pathway estimated by in vitro bioassay. Phytochemistry 2008, 69, 3117–3130.
    • (2008) Phytochemistry , vol.69 , pp. 3117-3130
    • Amakura, Y.1    Tsutsumi, T.2    Sasaki, K.3    Nakamura, M.4    Yoshida, T.5    Maitani, T.6
  • 116
    • 75149115740 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis
    • Fan, Y.; Boivin, G.P.; Knudsen, E.S.; Nebert, D.W.; Xia, Y.; Puga, A. The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis. Cancer Res. 2010, 70, 212–220.
    • (2010) Cancer Res , vol.70 , pp. 212-220
    • Fan, Y.1    Boivin, G.P.2    Knudsen, E.S.3    Nebert, D.W.4    Xia, Y.5    Puga, A.6
  • 117
    • 84919398687 scopus 로고    scopus 로고
    • Roles of tumor suppressors in regulating tumor-associated inflammation
    • Yang, L.; Karin, M. Roles of tumor suppressors in regulating tumor-associated inflammation. Cell Death Differ. 2014, 21, 1677–1686.
    • (2014) Cell Death Differ , vol.21 , pp. 1677-1686
    • Yang, L.1    Karin, M.2
  • 118
    • 84900988267 scopus 로고    scopus 로고
    • Chronic inflammation (Inflammaging) and its potential contribution to age-associated diseases
    • Franceschi, C.; Campisi, J. Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. J. Gerontol. A Biol. Sci. Med. Sci. 2014, 69 (Suppl 1), S4–S9.
    • (2014) J. Gerontol. a Biol. Sci. Med. Sci. , vol.69 , pp. S4-S9
    • Franceschi, C.1    Campisi, J.2
  • 119
    • 84899529457 scopus 로고    scopus 로고
    • NF-κβ signaling and chronic inflammatory diseases: Exploring the potential of natural products to drive new therapeutic opportunities
    • Killeen, M.J.; Linder, M.; Pontoniere, P.; Crea, R. NF-κβ signaling and chronic inflammatory diseases: Exploring the potential of natural products to drive new therapeutic opportunities. Drug Discov. Today 2014, 19, 373–378.
    • (2014) Drug Discov. Today , vol.19 , pp. 373-378
    • Killeen, M.J.1    Linder, M.2    Pontoniere, P.3    Crea, R.4
  • 120
    • 84923358567 scopus 로고    scopus 로고
    • Oleuropein suppresses LPS-induced inflammatory responses in RAW 264.7 cell and zebrafish
    • Ryu, S.-J.; Choi, H.-S.; Yoon, K.-Y.; Lee, O.-H.; Kim, K.-J.; Lee, B.-Y. Oleuropein suppresses LPS-induced inflammatory responses in RAW 264.7 cell and zebrafish. J. Agric. Food Chem. 2015, 63, 2098–2105.
    • (2015) J. Agric. Food Chem. , vol.63 , pp. 2098-2105
    • Ryu, S.-J.1    Choi, H.-S.2    Yoon, K.-Y.3    Lee, O.-H.4    Kim, K.-J.5    Lee, B.-Y.6
  • 121
    • 84891615140 scopus 로고    scopus 로고
    • Hydroxytyrosol suppresses MMP-9 and COX-2 activity and expression in activated human monocytes via PKCα and PKCβ1 inhibition
    • Scoditti, E.; Nestola, A.; Massaro, M.; Calabriso, N.; Storelli, C.; De Caterina, R.; Carluccio, M.A. Hydroxytyrosol suppresses MMP-9 and COX-2 activity and expression in activated human monocytes via PKCα and PKCβ1 inhibition. Atherosclerosis 2014, 232, 17–24.
    • (2014) Atherosclerosis , vol.232 , pp. 17-24
    • Scoditti, E.1    Nestola, A.2    Massaro, M.3    Calabriso, N.4    Storelli, C.5    De Caterina, R.6    Carluccio, M.A.7
  • 122
    • 84946412063 scopus 로고    scopus 로고
    • Cyclooxygenase-2 promotes tumor growth and suppresses tumor immunity
    • Liu, B.; Qu, L.; Yan, S. Cyclooxygenase-2 promotes tumor growth and suppresses tumor immunity. Cancer Cell Int. 2015, 15, 106.
    • (2015) Cancer Cell Int , vol.15 , pp. 106
    • Liu, B.1    Qu, L.2    Yan, S.3
  • 123
    • 84867101055 scopus 로고    scopus 로고
    • Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: A potentially protective mechanism in atherosclerotic vascular disease and cancer
    • Scoditti, E.; Calabriso, N.; Massaro, M.; Pellegrino, M.; Storelli, C.; Martines, G.; De Caterina, R.; Carluccio, M.A. Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: A potentially protective mechanism in atherosclerotic vascular disease and cancer. Arch. Biochem. Biophys. 2012, 527, 81–89.
    • (2012) Arch. Biochem. Biophys. , vol.527 , pp. 81-89
    • Scoditti, E.1    Calabriso, N.2    Massaro, M.3    Pellegrino, M.4    Storelli, C.5    Martines, G.6    De Caterina, R.7    Carluccio, M.A.8
  • 124
    • 64749111428 scopus 로고    scopus 로고
    • Hydroxytyrosol inhibits pro-inflammatory cytokines, iNOS, and COX-2 expression in human monocytic cells
    • Zhang, X.; Cao, J.; Zhong, L. Hydroxytyrosol inhibits pro-inflammatory cytokines, iNOS, and COX-2 expression in human monocytic cells. Naunyn Schmied. Arch. Pharmacol. 2009, 379, 581–586.
    • (2009) Naunyn Schmied. Arch. Pharmacol. , vol.379 , pp. 581-586
    • Zhang, X.1    Cao, J.2    Zhong, L.3
  • 125
    • 84928114818 scopus 로고    scopus 로고
    • The hydroxytyrosol-dependent increase of TNF-α in LPS-activated human monocytes is mediated by PGE2 and adenylate cyclase activation
    • Fuccelli, R.; Fabiani, R.; Sepporta, M.V.; Rosignoli, P. The hydroxytyrosol-dependent increase of TNF-α in LPS-activated human monocytes is mediated by PGE2 and adenylate cyclase activation. Toxicol. Vitro 2015, 29, 933–937.
    • (2015) Toxicol. Vitro , vol.29 , pp. 933-937
    • Fuccelli, R.1    Fabiani, R.2    Sepporta, M.V.3    Rosignoli, P.4
  • 126
    • 84952865495 scopus 로고    scopus 로고
    • Olive oil compounds inhibit the paracrine regulation of TNF-α-induced endothelial cell migration through reduced glioblastoma cell cyclooxygenase-2 expression
    • Lamy, S.; Ben Saad, A.; Zgheib, A.; Annabi, B. Olive oil compounds inhibit the paracrine regulation of TNF-α-induced endothelial cell migration through reduced glioblastoma cell cyclooxygenase-2 expression. J. Nutr. Biochem. 2015, 27, 136–145.
    • (2015) J. Nutr. Biochem. , vol.27 , pp. 136-145
    • Lamy, S.1    Ben Saad, A.2    Zgheib, A.3    Annabi, B.4
  • 127
    • 84908256293 scopus 로고    scopus 로고
    • Biphasic effects of luteolin on interleukin-1β-induced cyclooxygenase-2 expression in glioblastoma cells
    • Lamy, S.; Moldovan, P.L.; Ben Saad, A.; Annabi, B. Biphasic effects of luteolin on interleukin-1β-induced cyclooxygenase-2 expression in glioblastoma cells. Biochim. Biophys. Acta 2015, 1853, 126–135.
    • (2015) Biochim. Biophys. Acta , vol.1853 , pp. 126-135
    • Lamy, S.1    Moldovan, P.L.2    Ben Saad, A.3    Annabi, B.4
  • 129
    • 84920149720 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and the inflammogenesis of breast cancer
    • Harris, R.E.; Casto, B.C.; Harris, Z.M. Cyclooxygenase-2 and the inflammogenesis of breast cancer. World J. Clin. Oncol. 2014, 5, 677–692.
    • (2014) World J. Clin. Oncol. , vol.5 , pp. 677-692
    • Harris, R.E.1    Casto, B.C.2    Harris, Z.M.3
  • 130
    • 84901649848 scopus 로고    scopus 로고
    • COX-2 inhibitors arrest prostate cancer cell cycle progression by down-regulation of kinetochore/centromere proteins
    • Bieniek, J.; Childress, C.; Swatski, M.D.; Yang, W. COX-2 inhibitors arrest prostate cancer cell cycle progression by down-regulation of kinetochore/centromere proteins. Prostate 2014, 74, 999–1011.
    • (2014) Prostate , vol.74 , pp. 999-1011
    • Bieniek, J.1    Childress, C.2    Swatski, M.D.3    Yang, W.4
  • 131
    • 84875171594 scopus 로고    scopus 로고
    • Prognostic significance of COX-2 immunohistochemical expression in colorectal cancer: A meta-analysis of the literature
    • Peng, L.; Zhou, Y.; Wang, Y.; Mou, H.; Zhao, Q. Prognostic significance of COX-2 immunohistochemical expression in colorectal cancer: A meta-analysis of the literature. PLoS ONE 2013, 8, e58891.
    • (2013) Plos ONE , vol.8
    • Peng, L.1    Zhou, Y.2    Wang, Y.3    Mou, H.4    Zhao, Q.5
  • 133
    • 33847238726 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibition: Effects on tumour growth, cell cycling and lymphangiogenesis in a xenograft model of breast cancer
    • Barnes, N.L.P.; Warnberg, F.; Farnie, G.; White, D.; Jiang, W.; Anderson, E.; Bundred, N.J. Cyclooxygenase-2 inhibition: Effects on tumour growth, cell cycling and lymphangiogenesis in a xenograft model of breast cancer. Br. J. Cancer 2007, 96, 575–582.
    • (2007) Br. J. Cancer , vol.96 , pp. 575-582
    • Barnes, N.L.P.1    Warnberg, F.2    Farnie, G.3    White, D.4    Jiang, W.5    Anderson, E.6    Bundred, N.J.7
  • 135
    • 84940440617 scopus 로고    scopus 로고
    • Synergistic effect between celecoxib and luteolin is dependent on estrogen receptor in human breast cancer cells
    • Jeon, Y.W.; Ahn, Y.E.; Chung, W.S.; Choi, H.J.; Suh, Y.J. Synergistic effect between celecoxib and luteolin is dependent on estrogen receptor in human breast cancer cells. Tumor Biol. 2015, 36, 6349–6359.
    • (2015) Tumor Biol , vol.36 , pp. 6349-6359
    • Jeon, Y.W.1    Ahn, Y.E.2    Chung, W.S.3    Choi, H.J.4    Suh, Y.J.5
  • 136
    • 33744933461 scopus 로고    scopus 로고
    • HER-2/neu status is a determinant of mammary aromatase activity in vivo: Evidence for a cyclooxygenase-2-dependent mechanism
    • Subbaramaiah, K.; Howe, L.R.; Port, E.R.; Brogi, E.; Fishman, J.; Liu, C.H.; Hla, T.; Hudis, C.; Dannenberg, A.J. HER-2/neu status is a determinant of mammary aromatase activity in vivo: Evidence for a cyclooxygenase-2-dependent mechanism. Cancer Res. 2006, 66, 5504–5511.
    • (2006) Cancer Res , vol.66 , pp. 5504-5511
    • Subbaramaiah, K.1    Howe, L.R.2    Port, E.R.3    Brogi, E.4    Fishman, J.5    Liu, C.H.6    Hla, T.7    Hudis, C.8    Dannenberg, A.J.9
  • 137
    • 84866250761 scopus 로고    scopus 로고
    • Increased levels of COX-2 and prostaglandin E2 contribute to elevated aromatase expression in inflamed breast tissue of obese women
    • Subbaramaiah, K.; Morris, P.G.; Zhou, X.K.; Morrow, M.; Du, B.; Giri, D.; Kopelovich, L.; Hudis, C.A.; Dannenberg, A.J. Increased levels of COX-2 and prostaglandin E2 contribute to elevated aromatase expression in inflamed breast tissue of obese women. Cancer Discov. 2012, 2, 356–365.
    • (2012) Cancer Discov , vol.2 , pp. 356-365
    • Subbaramaiah, K.1    Morris, P.G.2    Zhou, X.K.3    Morrow, M.4    Du, B.5    Giri, D.6    Kopelovich, L.7    Hudis, C.A.8    Dannenberg, A.J.9
  • 139
    • 84923205376 scopus 로고    scopus 로고
    • Prostaglandin E2 inhibits p53 in human breast adipose stromal cells: A novel mechanism for the regulation of aromatase in obesity and breast cancer
    • Wang, X.; Docanto, M.M.; Sasano, H.; Lo, C.; Simpson, E.R.; Brown, K.A. Prostaglandin E2 inhibits p53 in human breast adipose stromal cells: A novel mechanism for the regulation of aromatase in obesity and breast cancer. Cancer Res. 2015, 75, 645–655.
    • (2015) Cancer Res , vol.75 , pp. 645-655
    • Wang, X.1    Docanto, M.M.2    Sasano, H.3    Lo, C.4    Simpson, E.R.5    Brown, K.A.6
  • 140
    • 84904599596 scopus 로고    scopus 로고
    • Oleuropein Induced Apoptosis in HeLa Cells via a Mitochondrial Apoptotic Cascade Associated With Activation of the c-Jun NH2-Terminal Kinase
    • Yao, J.; Wu, J.; Yang, X.; Yang, J.; Zhang, Y.; Du, L. Oleuropein Induced Apoptosis in HeLa Cells via a Mitochondrial Apoptotic Cascade Associated With Activation of the c-Jun NH2-Terminal Kinase. J. Pharmacol. Sci. 2014, 125, 300–311.
    • (2014) J. Pharmacol. Sci. , vol.125 , pp. 300-311
    • Yao, J.1    Wu, J.2    Yang, X.3    Yang, J.4    Zhang, Y.5    Du, L.6
  • 141
    • 84855361145 scopus 로고    scopus 로고
    • Regulation of immune responses by prostaglandin E2
    • Kalinski, P. Regulation of immune responses by prostaglandin E2. J. Immunol. 2012, 188, 21–28.
    • (2012) J. Immunol. , vol.188 , pp. 21-28
    • Kalinski, P.1
  • 143
    • 84887444879 scopus 로고    scopus 로고
    • Microenvironmental regulation of tumor progression and metastasis
    • Quail, D.F.; Joyce, J.A. Microenvironmental regulation of tumor progression and metastasis. Nat. Med. 2013, 19, 1423–1437.
    • (2013) Nat. Med. , vol.19 , pp. 1423-1437
    • Quail, D.F.1    Joyce, J.A.2
  • 144
    • 84945152087 scopus 로고    scopus 로고
    • Cyclooxygenase-2 in tumor-associated macrophages promotes breast cancer cell survival by triggering a positive-feedback loop between macrophages and cancer cells
    • Li, H.; Yang, B.; Huang, J.; Lin, Y.; Xiang, T.; Wan, J.; Li, H.; Chouaib, S.; Ren, G. Cyclooxygenase-2 in tumor-associated macrophages promotes breast cancer cell survival by triggering a positive-feedback loop between macrophages and cancer cells. Oncotarget 2015, 6, 29637–29650.
    • (2015) Oncotarget , vol.6 , pp. 29637-29650
    • Li, H.1    Yang, B.2    Huang, J.3    Lin, Y.4    Xiang, T.5    Wan, J.6    Li, H.7    Chouaib, S.8    Ren, G.9
  • 149
    • 84941954850 scopus 로고    scopus 로고
    • Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases
    • Vann, K.R.; Sedgeman, C.A.; Gopas, J.; Golan-Goldhirsh, A.; Osheroff, N. Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases. Biochemistry 2015, 54, 4531–4541.
    • (2015) Biochemistry , vol.54 , pp. 4531-4541
    • Vann, K.R.1    Sedgeman, C.A.2    Gopas, J.3    Golan-Goldhirsh, A.4    Osheroff, N.5
  • 150
    • 84938071729 scopus 로고    scopus 로고
    • Phytoestrogens and risk of prostate cancer: A meta-analysis of observational studies
    • He, J.; Wang, S.; Zhou, M.; Yu, W.; Zhang, Y.; He, X. Phytoestrogens and risk of prostate cancer: A meta-analysis of observational studies. World J. Surg. Oncol. 2015, 13, 231.
    • (2015) World J. Surg. Oncol. , vol.13
    • He, J.1    Wang, S.2    Zhou, M.3    Yu, W.4    Zhang, Y.5    He, X.6


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