Cyclooxygenase-2 in tumor-associated macrophages promotes breast cancer cell survival by triggering a positive-feedback loop between macrophages and cancer cells

Oncotarget

Volumn 6, Issue 30, 2015, Pages 29637-29650

  Li, Hongzhong ^a   Yang, Bing ^a   Huang, Jing ^a   Lin, Yong ^a   Xiang, Tingxiu ^a   Wan, Jingyuan ^a   Li, Hongyuan ^a   Chouaib, Salem ^b   Ren, Guosheng ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

Breast cancer; Cyclooxygenase 2; Macrophages; Prostaglandin E2; Tumor microenvironment

Indexed keywords

CYCLOOXYGENASE 2; MULTIDRUG RESISTANCE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN M2; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL; CANCER PROGNOSIS; CELL ACTIVITY; CELL POLARITY; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PHENOTYPE; POSITIVE FEEDBACK; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR ASSOCIATED LEUKOCYTE; ANIMAL; BREAST TUMOR; CELL CULTURE; CELL LINE; COCULTURE; DRUG EFFECTS; ENZYMOLOGY; FEEDBACK SYSTEM; GENE EXPRESSION REGULATION; GENETICS; HAIRLESS MOUSE; HUMAN; KNOCKOUT MOUSE; MACROPHAGE; MCF-7 CELL LINE; METABOLISM; MIDDLE AGED; PATHOLOGY; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCID MOUSE; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS REGULATORY PROTEINS; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; COCULTURE TECHNIQUES; CYCLOOXYGENASE 2; FEEDBACK, PHYSIOLOGICAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MACROPHAGES; MCF-7 CELLS; MICE, HAIRLESS; MICE, KNOCKOUT; MICE, SCID; MIDDLE AGED; PHOSPHATIDYLINOSITOL 3-KINASES; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84945152087     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4936     Document Type: Article

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