-
1
-
-
0242467932
-
Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells
-
Agarwal B, Swaroop P, Protiva P, Raj SV, Shirin H, Holt PR (2003) Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells. Apoptosis 8: 649-654
-
(2003)
Apoptosis
, vol.8
, pp. 649-654
-
-
Agarwal, B.1
Swaroop, P.2
Protiva, P.3
Raj, S.V.4
Shirin, H.5
Holt, P.R.6
-
2
-
-
15644381754
-
Role of translocation in the activation and function of protein kinase B
-
Andjelkovic M, Alessi DR, Meier R, Fernandez A, Lamb NJ, Frech M, Cron P, Cohen P, Lucocq JM, Hemmings BA (1997) Role of translocation in the activation and function of protein kinase B. J Biol Chem 272: 31515-31524
-
(1997)
J Biol Chem
, vol.272
, pp. 31515-31524
-
-
Andjelkovic, M.1
Alessi, D.R.2
Meier, R.3
Fernandez, A.4
Lamb, N.J.5
Frech, M.6
Cron, P.7
Cohen, P.8
Lucocq, J.M.9
Hemmings, B.A.10
-
3
-
-
1342301548
-
COX-2 expression is associated with an aggressive phenotype in ductal carcinoma in situ
-
Boland GP, Butt IS, Prasad R, Knox WF, Bundred NJ (2004) COX-2 expression is associated with an aggressive phenotype in ductal carcinoma in situ. Br J Cancer 90: 423-429
-
(2004)
Br J Cancer
, vol.90
, pp. 423-429
-
-
Boland, G.P.1
Butt, I.S.2
Prasad, R.3
Knox, W.F.4
Bundred, N.J.5
-
4
-
-
0034647674
-
Translocation of Akt/PKB to the nucleus of osteoblast-like MC3T3-E1 cells exposed to proliferative growth factors
-
Borgatti P, Martelli AM, Bellacosa A, Casto R, Massari L, Capitani S, Neri LM (2000) Translocation of Akt/PKB to the nucleus of osteoblast-like MC3T3-E1 cells exposed to proliferative growth factors. FEBS Lett 477: 27-32
-
(2000)
FEBS Lett
, vol.477
, pp. 27-32
-
-
Borgatti, P.1
Martelli, A.M.2
Bellacosa, A.3
Casto, R.4
Massari, L.5
Capitani, S.6
Neri, L.M.7
-
5
-
-
0034707105
-
-
Bombardier C, Laine L, Reicin A, Shapiro D, Burgos-Vargas R, Davis B, Day R, Ferraz MB, Hawkey CJ, Hochberg HC, Kvien TK, Schnitzer TJ, VIGOR Study Group (2000) Comparison of upper Gastrointestinal toxicity of Rofecoxib and Naproxen in patients with rheumatoid arthritis. N Eng J Med 343: 1520-1528
-
Bombardier C, Laine L, Reicin A, Shapiro D, Burgos-Vargas R, Davis B, Day R, Ferraz MB, Hawkey CJ, Hochberg HC, Kvien TK, Schnitzer TJ, VIGOR Study Group (2000) Comparison of upper Gastrointestinal toxicity of Rofecoxib and Naproxen in patients with rheumatoid arthritis. N Eng J Med 343: 1520-1528
-
-
-
-
6
-
-
19744380776
-
Adenomatous Polyp Prevention on Vioxx (APPROVe) Trial Investigators
-
Bresalier RS, Sandler RS, Quan H, Bolognese JA, Oxenius B, Horgan K, Lines C, Riddell R, Morton D, Lanas A, Konstam MA, Baron JA (2005) Adenomatous Polyp Prevention on Vioxx (APPROVe) Trial Investigators. N Engl J Med 352: 1092-1107
-
(2005)
N Engl J Med
, vol.352
, pp. 1092-1107
-
-
Bresalier, R.S.1
Sandler, R.S.2
Quan, H.3
Bolognese, J.A.4
Oxenius, B.5
Horgan, K.6
Lines, C.7
Riddell, R.8
Morton, D.9
Lanas, A.10
Konstam, M.A.11
Baron, J.A.12
-
7
-
-
0036143027
-
Effect of epidermal growth factor receptor tyrosine kinase inhibition on epithelial proliferation in normal and premalignant breast
-
Chan KC, Knox WF, Gee JM, Morris J, Nicholson RI, Potten CS, Bundred NJ (2002) Effect of epidermal growth factor receptor tyrosine kinase inhibition on epithelial proliferation in normal and premalignant breast. Cancer Res 62: 122-128
-
(2002)
Cancer Res
, vol.62
, pp. 122-128
-
-
Chan, K.C.1
Knox, W.F.2
Gee, J.M.3
Morris, J.4
Nicholson, R.I.5
Potten, C.S.6
Bundred, N.J.7
-
8
-
-
0036423877
-
Cyclooxygenase-2 inhibitor blocks expression of mediators of renal injury in a model of diabetes and hypertension
-
Cheng HF, Wang CJ, Moeckel GW, Zhang MZ, McKanna JA, Harris RC (2002) Cyclooxygenase-2 inhibitor blocks expression of mediators of renal injury in a model of diabetes and hypertension. Kidney Int 62: 929-939
-
(2002)
Kidney Int
, vol.62
, pp. 929-939
-
-
Cheng, H.F.1
Wang, C.J.2
Moeckel, G.W.3
Zhang, M.Z.4
McKanna, J.A.5
Harris, R.C.6
-
9
-
-
0037100867
-
Cyclo-oxygenase inhibition reduces tumour growth and metastasis in an orthotopic model of breast cancer
-
Connolly EM, Harmey JH, O'Grady T, Foley D, Roche-Nagle G, Kay E, Bouchier-Hayes DJ (2002) Cyclo-oxygenase inhibition reduces tumour growth and metastasis in an orthotopic model of breast cancer. Br J Cancer 87: 231- 237
-
(2002)
Br J Cancer
, vol.87
, pp. 231-237
-
-
Connolly, E.M.1
Harmey, J.H.2
O'Grady, T.3
Foley, D.4
Roche-Nagle, G.5
Kay, E.6
Bouchier-Hayes, D.J.7
-
10
-
-
1642503735
-
Histologically normal human mammary epithelia with silenced p16(INK4a) overexpress COX-2, promoting a premalignant program
-
Crawford YG, Gauthier ML, Joubel A, Mantei K, Kozakiewicz K, Afshari CA, Tlsty TD (2004) Histologically normal human mammary epithelia with silenced p16(INK4a) overexpress COX-2, promoting a premalignant program. Cancer Cell 5: 263-273
-
(2004)
Cancer Cell
, vol.5
, pp. 263-273
-
-
Crawford, Y.G.1
Gauthier, M.L.2
Joubel, A.3
Mantei, K.4
Kozakiewicz, K.5
Afshari, C.A.6
Tlsty, T.D.7
-
11
-
-
1642333026
-
Levels of expression of endothelial markers specific to tumour-associated endothelial cells and their correlation with prognosis in patients with breast cancer
-
Davies G, Cunnick GH, Mansel RE, Mason MD, Jiang WG (2004) Levels of expression of endothelial markers specific to tumour-associated endothelial cells and their correlation with prognosis in patients with breast cancer. Clin Exp Metastasis 21: 31-37
-
(2004)
Clin Exp Metastasis
, vol.21
, pp. 31-37
-
-
Davies, G.1
Cunnick, G.H.2
Mansel, R.E.3
Mason, M.D.4
Jiang, W.G.5
-
12
-
-
0035943611
-
Prostaglandin E(2) regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1 beta-treated human synovial fibroblasts
-
Faour WH, He Y, He QW, de Ladurantaye M, Quintero M, Mancini A, Di Battista JA (2001) Prostaglandin E(2) regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1 beta-treated human synovial fibroblasts. J Biol Chem 276: 31720-31731
-
(2001)
J Biol Chem
, vol.276
, pp. 31720-31731
-
-
Faour, W.H.1
He, Y.2
He, Q.W.3
de Ladurantaye, M.4
Quintero, M.5
Mancini, A.6
Di Battista, J.A.7
-
13
-
-
0025005862
-
The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes
-
Fu JY, Masferrer JL, Seibert K, Raz A, Needleman P (1990) The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes. J Biol Chem 265: 16737-16740
-
(1990)
J Biol Chem
, vol.265
, pp. 16737-16740
-
-
Fu, J.Y.1
Masferrer, J.L.2
Seibert, K.3
Raz, A.4
Needleman, P.5
-
14
-
-
0033891772
-
Effects of a pure antiestrogen on apoptosis and proliferation within human breast ductal carcinoma in situ
-
Gandhi A, Holland PA, Knox WF, Potten CS, Bundred NJ (2000) Effects of a pure antiestrogen on apoptosis and proliferation within human breast ductal carcinoma in situ. Cancer Res 60: 4284-4288
-
(2000)
Cancer Res
, vol.60
, pp. 4284-4288
-
-
Gandhi, A.1
Holland, P.A.2
Knox, W.F.3
Potten, C.S.4
Bundred, N.J.5
-
15
-
-
0141963117
-
Inhibitors of cyclooxygenase 2: A new class of anticancer agents?
-
Gasparini G, Longo R, Sarmiento R, Morabito A (2003) Inhibitors of cyclooxygenase 2: a new class of anticancer agents? Lancet Oncol 4: 605-615
-
(2003)
Lancet Oncol
, vol.4
, pp. 605-615
-
-
Gasparini, G.1
Longo, R.2
Sarmiento, R.3
Morabito, A.4
-
16
-
-
0141842615
-
Breast cancer and nonsteroidal anti-inflammatory drugs: Prospective results from the Women's Health Initiative
-
Harris RE, Chlebowski RT, Jackson RD, Frid DJ, Ascenseo JL, Anderson G, Loar A, Rodabough RJ, White E, McTiernan A (2003) Breast cancer and nonsteroidal anti-inflammatory drugs: prospective results from the Women's Health Initiative. Cancer Res 63: 6096-6101
-
(2003)
Cancer Res
, vol.63
, pp. 6096-6101
-
-
Harris, R.E.1
Chlebowski, R.T.2
Jackson, R.D.3
Frid, D.J.4
Ascenseo, J.L.5
Anderson, G.6
Loar, A.7
Rodabough, R.J.8
White, E.9
McTiernan, A.10
-
17
-
-
0036792206
-
Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer
-
Howe LR, Subbaramaiah K, Patel J, Masferrer JL, Deora A, Hudis C, Thaler HT, Muller WJ, Du B, Brown AM, Dannenberg AJ (2002) Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer. Cancer Res 62: 5405-5407
-
(2002)
Cancer Res
, vol.62
, pp. 5405-5407
-
-
Howe, L.R.1
Subbaramaiah, K.2
Patel, J.3
Masferrer, J.L.4
Deora, A.5
Hudis, C.6
Thaler, H.T.7
Muller, W.J.8
Du, B.9
Brown, A.M.10
Dannenberg, A.J.11
-
18
-
-
0034646688
-
The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2
-
Hsu AL, Ching TT, Wang DS, Song X, Rangnekar VM, Chen CS (2000) The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2. J Biol Chem 275: 11397- 11403
-
(2000)
J Biol Chem
, vol.275
, pp. 11397-11403
-
-
Hsu, A.L.1
Ching, T.T.2
Wang, D.S.3
Song, X.4
Rangnekar, V.M.5
Chen, C.S.6
-
19
-
-
12344291466
-
Patients exposed to Rofecoxib and Celecoxib have different odds of non fatal myocardial infarction
-
Kimmel SE, Berlin JA, Reilly M, Jaskowiak J, Kishel L, Chittams J, Strom BL (2005) Patients exposed to Rofecoxib and Celecoxib have different odds of non fatal myocardial infarction. Ann Intern Med 142: 157-164
-
(2005)
Ann Intern Med
, vol.142
, pp. 157-164
-
-
Kimmel, S.E.1
Berlin, J.A.2
Reilly, M.3
Jaskowiak, J.4
Kishel, L.5
Chittams, J.6
Strom, B.L.7
-
20
-
-
0033560896
-
Direct control of the Forkhead transcription factor AFX by protein kinase B
-
Kops GJ, de Ruiter ND, De Vries-Smits AM, Powell DR, Bos JL, Burgering BM (1999) Direct control of the Forkhead transcription factor AFX by protein kinase B. Nature 398: 630- 634
-
(1999)
Nature
, vol.398
, pp. 630-634
-
-
Kops, G.J.1
de Ruiter, N.D.2
De Vries-Smits, A.M.3
Powell, D.R.4
Bos, J.L.5
Burgering, B.M.6
-
21
-
-
0041822007
-
Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: Evidence for Akt inhibition in celecoxib-induced apoptosis
-
Leng J, Han C, Demetris AJ, Michalopoulos GK, Wu T (2003) Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: evidence for Akt inhibition in celecoxib-induced apoptosis. Hepatology 38: 756-768
-
(2003)
Hepatology
, vol.38
, pp. 756-768
-
-
Leng, J.1
Han, C.2
Demetris, A.J.3
Michalopoulos, G.K.4
Wu, T.5
-
22
-
-
0035947709
-
Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice
-
Liu CH, Chang SH, Narko K, Trifan OC, Wu MT, Smith E, Haudenschild C, Lane TF, Hla T (2001) Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J Biol Chem 276: 18563-18569
-
(2001)
J Biol Chem
, vol.276
, pp. 18563-18569
-
-
Liu, C.H.1
Chang, S.H.2
Narko, K.3
Trifan, O.C.4
Wu, M.T.5
Smith, E.6
Haudenschild, C.7
Lane, T.F.8
Hla, T.9
-
23
-
-
0034161878
-
Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors
-
Masferrer JL, Leahy KM, Koki AT, Zweifel BS, Settle SL, Woerner BM, Edwards DA, Flickinger AG, Moore RJ, Seibert K (2000) Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors. Cancer Res 60: 1306-1311
-
(2000)
Cancer Res
, vol.60
, pp. 1306-1311
-
-
Masferrer, J.L.1
Leahy, K.M.2
Koki, A.T.3
Zweifel, B.S.4
Settle, S.L.5
Woerner, B.M.6
Edwards, D.A.7
Flickinger, A.G.8
Moore, R.J.9
Seibert, K.10
-
24
-
-
4444305435
-
Elevated cyclooxygenase-2 expression correlates with distant metastases in breast cancer
-
Ranger GS, Thomas V, Jewell A, Mokbel K (2004) Elevated cyclooxygenase-2 expression correlates with distant metastases in breast cancer. Anticancer Res 24: 2349-2351
-
(2004)
Anticancer Res
, vol.24
, pp. 2349-2351
-
-
Ranger, G.S.1
Thomas, V.2
Jewell, A.3
Mokbel, K.4
-
25
-
-
0033546439
-
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B
-
Rena G, Guo S, Cichy SC, Unterman TG, Cohen P (1999) Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B. J Biol Chem 274: 17179-17183
-
(1999)
J Biol Chem
, vol.274
, pp. 17179-17183
-
-
Rena, G.1
Guo, S.2
Cichy, S.C.3
Unterman, T.G.4
Cohen, P.5
-
26
-
-
3843074311
-
Antimetastatic activity of a cyclooxygenase-2 inhibitor
-
Roche-Nagle G, Connolly EM, Eng M, Bouchier-Hayes DJ, Harmey JH (2004) Antimetastatic activity of a cyclooxygenase-2 inhibitor. Br J Cancer 91: 359-365
-
(2004)
Br J Cancer
, vol.91
, pp. 359-365
-
-
Roche-Nagle, G.1
Connolly, E.M.2
Eng, M.3
Bouchier-Hayes, D.J.4
Harmey, J.H.5
-
27
-
-
3242771185
-
Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: Correlation with suppression of COX-2 synthesis
-
Shishodia S, Koul D, Aggarwal BB (2004) Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis. J Immunol 173: 2011-2022
-
(2004)
J Immunol
, vol.173
, pp. 2011-2022
-
-
Shishodia, S.1
Koul, D.2
Aggarwal, B.B.3
-
28
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL (1987) Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235: 177-182
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
29
-
-
0033791318
-
Cyclooxygenases: Structural, cellular, and molecular biology
-
Smith WL, DeWitt DL, Garavito RM (2000) Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem 69: 145-182
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 145-182
-
-
Smith, W.L.1
DeWitt, D.L.2
Garavito, R.M.3
-
30
-
-
20144365496
-
Cardiovascular risk associated with Celecoxib in a clinical trial for Colorectal Adenoma Prevention
-
Adenoma prevention with Celecoxib (APC) study investigators
-
Solomon SD, McMurray JJ, Pfeffer MA, Wittes J, Fowler R, Finn P, Anderson WF, Zauber A, Hawk E, Bertagonolli M, Adenoma prevention with Celecoxib (APC) study investigators (2005) Cardiovascular risk associated with Celecoxib in a clinical trial for Colorectal Adenoma Prevention. N Eng J Med 352: 1071-1080
-
(2005)
N Eng J Med
, vol.352
, pp. 1071-1080
-
-
Solomon, S.D.1
McMurray, J.J.2
Pfeffer, M.A.3
Wittes, J.4
Fowler, R.5
Finn, P.6
Anderson, W.F.7
Zauber, A.8
Hawk, E.9
Bertagonolli, M.10
-
31
-
-
0037579491
-
Predicting local recurrence in pateints with ductal carcinoma in situ
-
MJ Silverstein (ed) Chapter 21, pp, Lippncott, Williams and Wilkins: Philadelphia, USA
-
Sposto R, Silverstein MJ (2002) Predicting local recurrence in pateints with ductal carcinoma in situ. In Ductal Carcinoma In Situ of the Breast, MJ Silverstein (ed) Chapter 21, pp. 255-263. Lippncott, Williams and Wilkins: Philadelphia, USA
-
(2002)
Ductal Carcinoma In Situ of the Breast
, pp. 255-263
-
-
Sposto, R.1
Silverstein, M.J.2
-
32
-
-
1642475162
-
Cyclooxygenase-2 induces EP1- and HER-2/Neu-dependent vascular endothelial growth factor-C up-regulation: A novel mechanism of lymphangiogenesis in lung adenocarcinoma
-
Su JL, Shih JY, Yen ML, Jeng YM, Chang CC, Hsieh CY, Wei LH, Yang PC, Kuo ML (2004) Cyclooxygenase-2 induces EP1- and HER-2/Neu-dependent vascular endothelial growth factor-C up-regulation: a novel mechanism of lymphangiogenesis in lung adenocarcinoma. Cancer Res 64: 554-564
-
(2004)
Cancer Res
, vol.64
, pp. 554-564
-
-
Su, J.L.1
Shih, J.Y.2
Yen, M.L.3
Jeng, Y.M.4
Chang, C.C.5
Hsieh, C.Y.6
Wei, L.H.7
Yang, P.C.8
Kuo, M.L.9
-
33
-
-
0029783253
-
Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells
-
Subbaramaiah K, Telang N, Ramonetti JT, Araki R, DeVito B, Weksler BB, Dannenberg AJ (1996) Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells. Cancer Res 56: 4424-4429
-
(1996)
Cancer Res
, vol.56
, pp. 4424-4429
-
-
Subbaramaiah, K.1
Telang, N.2
Ramonetti, J.T.3
Araki, R.4
DeVito, B.5
Weksler, B.B.6
Dannenberg, A.J.7
-
34
-
-
0025754779
-
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
-
Xie WL, Chipman JG, Robertson DL, Erikson RL, Simmons DL (1991) Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA 88: 2692-2696
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 2692-2696
-
-
Xie, W.L.1
Chipman, J.G.2
Robertson, D.L.3
Erikson, R.L.4
Simmons, D.L.5
|