-
1
-
-
80052303130
-
Autophagy and aging
-
21884931
-
D.C.Rubinsztein, G.Marino, G.Kroemer. Autophagy and aging. Cell 2011; 146:682-95; PMID:21884931; http://dx.doi.org/10.1016/j.cell.2011.07.030
-
(2011)
Cell
, vol.146
, pp. 682-695
-
-
Rubinsztein, D.C.1
Marino, G.2
Kroemer, G.3
-
2
-
-
84989284335
-
Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies
-
25766616
-
A.Ciechanover, Y.T.Kwon. Degradation of misfolded proteins in neurodegenerative diseases:therapeutic targets and strategies. Exp Mol Med 2015; 47:e147; PMID:25766616; http://dx.doi.org/10.1038/emm.2014.117
-
(2015)
Exp Mol Med
, vol.47
, pp. e147
-
-
Ciechanover, A.1
Kwon, Y.T.2
-
3
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
11099404
-
D.J.Klionsky, S.D.Emr. Autophagy as a regulated pathway of cellular degradation. Science 2000; 290:1717-21; PMID:11099404; http://dx.doi.org/10.1126/science.290.5497.1717
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
4
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
21258367
-
J.Kim, M.Kundu, B.Viollet, K.L.Guan. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 2011; 13:132-41; PMID:21258367; http://dx.doi.org/10.1038/ncb2152
-
(2011)
Nat Cell Biol
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
5
-
-
80955177196
-
TFEB links autophagy to lysosomal biogenesis
-
21617040
-
C.Settembre, C.Di Malta, V.A.Polito, M.Garcia Arencibia, F.Vetrini, S.Erdin, S.U.Erdin, T.Huynh, D.Medina, P.Colella, et al. TFEB links autophagy to lysosomal biogenesis. Science 2011; 332:1429-33; PMID:21617040; http://dx.doi.org/10.1126/science.1204592
-
(2011)
Science
, vol.332
, pp. 1429-1433
-
-
Settembre, C.1
Di Malta, C.2
Polito, V.A.3
Garcia Arencibia, M.4
Vetrini, F.5
Erdin, S.6
Erdin, S.U.7
Huynh, T.8
Medina, D.9
Colella, P.10
-
6
-
-
84922968506
-
Transcriptional regulation of autophagy by an FXR-CREB axis
-
25383523
-
S.Seok, T.Fu, S.E.Choi, Y.Li, R.Zhu, S.Kumar, X.Sun, G.Yoon, Y.Kang, W.Zhong, et al. Transcriptional regulation of autophagy by an FXR-CREB axis. Nature 2014; 516:108-11; PMID:25383523
-
(2014)
Nature
, vol.516
, pp. 108-111
-
-
Seok, S.1
Fu, T.2
Choi, S.E.3
Li, Y.4
Zhu, R.5
Kumar, S.6
Sun, X.7
Yoon, G.8
Kang, Y.9
Zhong, W.10
-
7
-
-
84874192375
-
FOXO3A directs a protective autophagy program in haematopoietic stem cells
-
23389440
-
M.R.Warr, M.Binnewies, J.Flach, D.Reynaud, T.Garg, R.Malhotra, J.Debnath, E.Passegué. FOXO3A directs a protective autophagy program in haematopoietic stem cells. Nature 2013; 494:323-7; PMID:23389440; http://dx.doi.org/10.1038/nature11895
-
(2013)
Nature
, vol.494
, pp. 323-327
-
-
Warr, M.R.1
Binnewies, M.2
Flach, J.3
Reynaud, D.4
Garg, T.5
Malhotra, R.6
Debnath, J.7
Passegué, E.8
-
8
-
-
84939787271
-
Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism
-
26168401
-
R.M.Perera, S.Stoykova, B.N.Nicolay, K.N.Ross, J.Fitamant, M.Boukhali, J.Lengrand, V.Deshpande, M.K.Selig, C.R.Ferrone, et al. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature 2015; 524:361-5; PMID:26168401; http://dx.doi.org/10.1038/nature14587
-
(2015)
Nature
, vol.524
, pp. 361-365
-
-
Perera, R.M.1
Stoykova, S.2
Nicolay, B.N.3
Ross, K.N.4
Fitamant, J.5
Boukhali, M.6
Lengrand, J.7
Deshpande, V.8
Selig, M.K.9
Ferrone, C.R.10
-
9
-
-
84876090708
-
ZKSCAN3 is a master transcriptional repressor of autophagy
-
23434374
-
S.Chauhan, J.G.Goodwin, S.Chauhan, G.Manyam, J.Wang, A.M.Kamat, D.D.Boyd. ZKSCAN3 is a master transcriptional repressor of autophagy. Mol Cell 2013; 50:16-28; PMID:23434374; http://dx.doi.org/10.1016/j.molcel.2013.01.024
-
(2013)
Mol Cell
, vol.50
, pp. 16-28
-
-
Chauhan, S.1
Goodwin, J.G.2
Chauhan, S.3
Manyam, G.4
Wang, J.5
Kamat, A.M.6
Boyd, D.D.7
-
10
-
-
84927175720
-
Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs
-
25402684
-
C.J.Bowman, D.E.Ayer, B.D.Dynlacht. Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs. Nat Cell Biol 2014; 16:1202-14; PMID:25402684; http://dx.doi.org/10.1038/ncb3062
-
(2014)
Nat Cell Biol
, vol.16
, pp. 1202-1214
-
-
Bowman, C.J.1
Ayer, D.E.2
Dynlacht, B.D.3
-
11
-
-
84940858852
-
Transcriptional and epigenetic regulation of autophagy in aging
-
25836756
-
L.R.Lapierre, C.Kumsta, M.Sandri, A.Ballabio, M.Hansen. Transcriptional and epigenetic regulation of autophagy in aging. Autophagy 2015; 11:867-80; PMID:25836756; http://dx.doi.org/10.1080/15548627.2015.1034410
-
(2015)
Autophagy
, vol.11
, pp. 867-880
-
-
Lapierre, L.R.1
Kumsta, C.2
Sandri, M.3
Ballabio, A.4
Hansen, M.5
-
12
-
-
84927636147
-
Regulation of autophagy and the ubiquitin-proteasome system by the FoxO transcriptional network during muscle atrophy
-
25858807
-
G.Milan, V.Romanello, F.Pescatore, A.Armani, J.H.Paik, L.Frasson, A.Seydel, J.Zhao, R.Abraham, A.L.Goldberg, et al. Regulation of autophagy and the ubiquitin-proteasome system by the FoxO transcriptional network during muscle atrophy. Nat Commun 2015; 6:6670; PMID:25858807; http://dx.doi.org/10.1038/ncomms7670
-
(2015)
Nat Commun
, vol.6
, pp. 6670
-
-
Milan, G.1
Romanello, V.2
Pescatore, F.3
Armani, A.4
Paik, J.H.5
Frasson, L.6
Seydel, A.7
Zhao, J.8
Abraham, R.9
Goldberg, A.L.10
-
13
-
-
84897421970
-
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
-
24647116
-
J.D.Hayes, A.T.Dinkova-Kostova. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Trends Biochem Sci 2014; 39:199-218; PMID:24647116; http://dx.doi.org/10.1016/j.tibs.2014.02.002
-
(2014)
Trends Biochem Sci
, vol.39
, pp. 199-218
-
-
Hayes, J.D.1
Dinkova-Kostova, A.T.2
-
14
-
-
84989795071
-
FRBM Special issue “Nrf2 regulated Redox Signaling and Metabolism in Physiology and Medicine” Molecular basis of the Keap1-Nrf2 system
-
T.Suzuki, M.Yamamoto. FRBM Special issue “Nrf2 regulated Redox Signaling and Metabolism in Physiology and Medicine” Molecular basis of the Keap1-Nrf2 system. Free Radic Biol Med 2015
-
(2015)
Free Radic Biol Med
-
-
Suzuki, T.1
Yamamoto, M.2
-
15
-
-
84970954340
-
p62 links autophagy and Nrf2 signaling
-
T.Jiang, B.Harder, M.R.Vega, P.K.Wong, E.Chapman, D.D.Zhang. p62 links autophagy and Nrf2 signaling. Free Radic Biol Med 2015; 88(Pt B):199-204
-
(2015)
Free Radic Biol Med
, vol.88
, pp. 199-204
-
-
Jiang, T.1
Harder, B.2
Vega, M.R.3
Wong, P.K.4
Chapman, E.5
Zhang, D.D.6
-
16
-
-
84883830467
-
Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy
-
24011591
-
Y.Ichimura, S.Waguri, Y.S.Sou, S.Kageyama, J.Hasegawa, R.Ishimura, T.Saito, Y.Yang, T.Kouno, T.Fukutomi, et al. Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol Cell 2013; 51:618-31; PMID:24011591; http://dx.doi.org/10.1016/j.molcel.2013.08.003
-
(2013)
Mol Cell
, vol.51
, pp. 618-631
-
-
Ichimura, Y.1
Waguri, S.2
Sou, Y.S.3
Kageyama, S.4
Hasegawa, J.5
Ishimura, R.6
Saito, T.7
Yang, Y.8
Kouno, T.9
Fukutomi, T.10
-
17
-
-
77954599053
-
p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
-
20452972
-
A.Jain, T.Lamark, E.Sjottem, K.B.Larsen, J.A.Awuh, A.Overvatn, M.McMahon, J.D.Hayes, T.Johansen. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription. J Biol Chem 2010; 285:22576-91; PMID:20452972; http://dx.doi.org/10.1074/jbc.M110.118976
-
(2010)
J Biol Chem
, vol.285
, pp. 22576-22591
-
-
Jain, A.1
Lamark, T.2
Sjottem, E.3
Larsen, K.B.4
Awuh, J.A.5
Overvatn, A.6
McMahon, M.7
Hayes, J.D.8
Johansen, T.9
-
18
-
-
84897093101
-
Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52
-
24667209
-
C.Jo, S.Gundemir, S.Pritchard, Y.N.Jin, I.Rahman, G.V.Johnson. Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52. Nat Commun 2014; 5:3496; PMID:24667209
-
(2014)
Nat Commun
, vol.5
, pp. 3496
-
-
Jo, C.1
Gundemir, S.2
Pritchard, S.3
Jin, Y.N.4
Rahman, I.5
Johnson, G.V.6
-
19
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
16625204
-
T.Hara, K.Nakamura, M.Matsui, A.Yamamoto, Y.Nakahara, R.Suzuki-Migishima, M.Yokoyama, K.Mishima, I.Saito, H.Okano, et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 2006; 441:885-9; PMID:16625204; http://dx.doi.org/10.1038/nature04724
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
Yokoyama, M.7
Mishima, K.8
Saito, I.9
Okano, H.10
-
20
-
-
84866519178
-
Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway
-
22998728
-
K.Inoue, J.Rispoli, H.Kaphzan, E.Klann, E.I.Chen, J.Kim, M.Komatsu, A.Abeliovich. Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway. Mol Neurodegener 2012; 7:48; PMID:22998728; http://dx.doi.org/10.1186/1750-1326-7-48
-
(2012)
Mol Neurodegener
, vol.7
, pp. 48
-
-
Inoue, K.1
Rispoli, J.2
Kaphzan, H.3
Klann, E.4
Chen, E.I.5
Kim, J.6
Komatsu, M.7
Abeliovich, A.8
-
21
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
16625205
-
M.Komatsu, S.Waguri, T.Chiba, S.Murata, J.Iwata, I.Tanida, T.Ueno, M.Koike, Y.Uchiyama, E.Kominami, et al. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006; 441:880-4; PMID:16625205; http://dx.doi.org/10.1038/nature04723
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
Murata, S.4
Iwata, J.5
Tanida, I.6
Ueno, T.7
Koike, M.8
Uchiyama, Y.9
Kominami, E.10
-
22
-
-
77956063684
-
Alzheimer's disease: old problem, new views from transgenic and viral models
-
20332023
-
T.Jaworski, I.Dewachter, C.M.Seymour, P.Borghgraef, H.Devijver, S.Kugler, F.Van Leuven. Alzheimer's disease:old problem, new views from transgenic and viral models. Biochimica et biophysica acta 2010; 1802:808-18; PMID:20332023; http://dx.doi.org/10.1016/j.bbadis.2010.03.005
-
(2010)
Biochimica et biophysica acta
, vol.1802
, pp. 808-818
-
-
Jaworski, T.1
Dewachter, I.2
Seymour, C.M.3
Borghgraef, P.4
Devijver, H.5
Kugler, S.6
Van Leuven, F.7
-
23
-
-
38349046973
-
Autophagy, amyloidogenesis and Alzheimer disease
-
18032783
-
R.A.Nixon. Autophagy, amyloidogenesis and Alzheimer disease. J Cell Sci 2007; 120:4081-91; PMID:18032783; http://dx.doi.org/10.1242/jcs.019265
-
(2007)
J Cell Sci
, vol.120
, pp. 4081-4091
-
-
Nixon, R.A.1
-
24
-
-
49049096562
-
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease
-
18596167
-
B.Boland, A.Kumar, S.Lee, F.M.Platt, J.Wegiel, W.H.Yu, R.A.Nixon. Autophagy induction and autophagosome clearance in neurons:relationship to autophagic pathology in Alzheimer's disease. J Neurosci 2008; 28:6926-37; PMID:18596167; http://dx.doi.org/10.1523/JNEUROSCI.0800-08.2008
-
(2008)
J Neurosci
, vol.28
, pp. 6926-6937
-
-
Boland, B.1
Kumar, A.2
Lee, S.3
Platt, F.M.4
Wegiel, J.5
Yu, W.H.6
Nixon, R.A.7
-
25
-
-
84989795906
-
-
http://www.webcitation.org/query?url=https%3A%2F%2Fgenome.ucsc.edu%2F&date=2015-07-29
-
-
-
-
26
-
-
84989787571
-
-
http://www.webcitation.org/query?url=http%3A%2F%2Fjaspar.genereg.net%2F&date=2015-07-29
-
-
-
-
27
-
-
0037821802
-
Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression
-
12682069
-
M.McMahon, K.Itoh, M.Yamamoto, J.D.Hayes. Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression. J Biol Chem 2003; 278:21592-600; PMID:12682069; http://dx.doi.org/10.1074/jbc.M300931200
-
(2003)
J Biol Chem
, vol.278
, pp. 21592-21600
-
-
McMahon, M.1
Itoh, K.2
Yamamoto, M.3
Hayes, J.D.4
-
28
-
-
84878336762
-
The NRF2 activation and antioxidative response are not impaired overall during hyperoxia-induced lung epithelial cell death
-
23738042
-
H.R.Potteti, N.M.Reddy, T.K.Hei, D.V.Kalvakolanu, S.P.Reddy. The NRF2 activation and antioxidative response are not impaired overall during hyperoxia-induced lung epithelial cell death. Oxid Med Cell Longev 2013; 2013:798401; PMID:23738042; http://dx.doi.org/10.1155/2013/798401
-
(2013)
Oxid Med Cell Longev
, vol.2013
, pp. 798401
-
-
Potteti, H.R.1
Reddy, N.M.2
Hei, T.K.3
Kalvakolanu, D.V.4
Reddy, S.P.5
-
29
-
-
84946484413
-
S6K1 controls autophagosome maturation in autophagy induced by sulforaphane or serum deprivation
-
26054233
-
A.Hac, A.Domachowska, M.Narajczyk, K.Cyske, A.Pawlik, A.Herman-Antosiewicz. S6K1 controls autophagosome maturation in autophagy induced by sulforaphane or serum deprivation. Euro J Cell Biol 2015; 94(10):470-81; PMID:26054233
-
(2015)
Euro J Cell Biol
, vol.94
, Issue.10
, pp. 470-481
-
-
Hac, A.1
Domachowska, A.2
Narajczyk, M.3
Cyske, K.4
Pawlik, A.5
Herman-Antosiewicz, A.6
-
30
-
-
84907500316
-
Sulforaphane-induced autophagy flux prevents prion protein-mediated neurotoxicity through AMPK pathway
-
25130556
-
J.H.Lee, J.K.Jeong, S.Y.Park. Sulforaphane-induced autophagy flux prevents prion protein-mediated neurotoxicity through AMPK pathway. Neuroscience 2014; 278:31-9; PMID:25130556; http://dx.doi.org/10.1016/j.neuroscience.2014.07.072
-
(2014)
Neuroscience
, vol.278
, pp. 31-39
-
-
Lee, J.H.1
Jeong, J.K.2
Park, S.Y.3
-
31
-
-
84906219165
-
Sulforaphane induces autophagy through ERK activation in neuronal cells
-
24952354
-
C.Jo, S.Kim, S.J.Cho, K.J.Choi, S.M.Yun, Y.H.Koh, G.V.Johnson, S.I.Park. Sulforaphane induces autophagy through ERK activation in neuronal cells. FEBS Lett 2014; 588:3081-8; PMID:24952354; http://dx.doi.org/10.1016/j.febslet.2014.06.036
-
(2014)
FEBS Lett
, vol.588
, pp. 3081-3088
-
-
Jo, C.1
Kim, S.2
Cho, S.J.3
Choi, K.J.4
Yun, S.M.5
Koh, Y.H.6
Johnson, G.V.7
Park, S.I.8
-
32
-
-
40449098952
-
Amyloid activates GSK-3beta to aggravate neuronal tauopathy in bigenic mice
-
18258852
-
D.Terwel, D.Muyllaert, I.Dewachter, P.Borghgraef, S.Croes, H.Devijver, F.Van Leuven. Amyloid activates GSK-3beta to aggravate neuronal tauopathy in bigenic mice. Am J Pathol 2008; 172:786-98; PMID:18258852; http://dx.doi.org/10.2353/ajpath.2008.070904
-
(2008)
Am J Pathol
, vol.172
, pp. 786-798
-
-
Terwel, D.1
Muyllaert, D.2
Dewachter, I.3
Borghgraef, P.4
Croes, S.5
Devijver, H.6
Van Leuven, F.7
-
33
-
-
84922768870
-
Increased Alzheimer's disease-like pathology in the APP/ PS1DeltaE9 mouse model lacking Nrf2 through modulation of autophagy
-
25316599
-
G.Joshi, K.A.Gan, D.A.Johnson, J.A.Johnson. Increased Alzheimer's disease-like pathology in the APP/ PS1DeltaE9 mouse model lacking Nrf2 through modulation of autophagy. Neurobiol Aging 2015; 36:664-79; PMID:25316599; http://dx.doi.org/10.1016/j.neurobiolaging.2014.09.004
-
(2015)
Neurobiol Aging
, vol.36
, pp. 664-679
-
-
Joshi, G.1
Gan, K.A.2
Johnson, D.A.3
Johnson, J.A.4
-
34
-
-
33748080476
-
Neuronal sensitivity to kainic acid is dependent on the Nrf2-mediated actions of the antioxidant response element
-
16945104
-
A.D.Kraft, J.M.Lee, D.A.Johnson, Y.W.Kan, J.A.Johnson. Neuronal sensitivity to kainic acid is dependent on the Nrf2-mediated actions of the antioxidant response element. J Neurochem 2006; 98:1852-65; PMID:16945104; http://dx.doi.org/10.1111/j.1471-4159.2006.04019.x
-
(2006)
J Neurochem
, vol.98
, pp. 1852-1865
-
-
Kraft, A.D.1
Lee, J.M.2
Johnson, D.A.3
Kan, Y.W.4
Johnson, J.A.5
-
35
-
-
84938487642
-
KEAP1-NRF2 signalling and autophagy in protection against oxidative and reductive proteotoxicity
-
26205490
-
M.Dodson, M.Redmann, N.S.Rajasekaran, V.Darley-Usmar, J.Zhang. KEAP1-NRF2 signalling and autophagy in protection against oxidative and reductive proteotoxicity. Biochem J 2015; 469:347-55; PMID:26205490; http://dx.doi.org/10.1042/BJ20150568
-
(2015)
Biochem J
, vol.469
, pp. 347-355
-
-
Dodson, M.1
Redmann, M.2
Rajasekaran, N.S.3
Darley-Usmar, V.4
Zhang, J.5
-
36
-
-
80655134725
-
TFEB regulates autophagy: an integrated coordination of cellular degradation and recycling processes
-
21785263
-
C.Settembre, A.Ballabio. TFEB regulates autophagy:an integrated coordination of cellular degradation and recycling processes. Autophagy 2011; 7:1379-81; PMID:21785263; http://dx.doi.org/10.4161/auto.7.11.17166
-
(2011)
Autophagy
, vol.7
, pp. 1379-1381
-
-
Settembre, C.1
Ballabio, A.2
-
37
-
-
84885622468
-
Histone post-translational modifications regulate autophagy flux and outcome
-
23934085
-
J.Fullgrabe, D.J.Klionsky, B.Joseph. Histone post-translational modifications regulate autophagy flux and outcome. Autophagy 2013; 9:1621-3; PMID:23934085; http://dx.doi.org/10.4161/auto.25803
-
(2013)
Autophagy
, vol.9
, pp. 1621-1623
-
-
Fullgrabe, J.1
Klionsky, D.J.2
Joseph, B.3
-
38
-
-
84869043780
-
The predicted molecular weight of Nrf2: it is what it is not
-
22703241
-
A.Lau, W.Tian, S.A.Whitman, D.D.Zhang. The predicted molecular weight of Nrf2:it is what it is not. Antioxid Redox Signal 2013; 18:91-3; PMID:22703241; http://dx.doi.org/10.1089/ars.2012.4754
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 91-93
-
-
Lau, A.1
Tian, W.2
Whitman, S.A.3
Zhang, D.D.4
-
39
-
-
0029043995
-
Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins
-
7623813
-
K.Itoh, K.Igarashi, N.Hayashi, M.Nishizawa, M.Yamamoto. Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins. Mol Cell Biol 1995; 15:4184-93; PMID:7623813; http://dx.doi.org/10.1128/MCB.15.8.4184
-
(1995)
Mol Cell Biol
, vol.15
, pp. 4184-4193
-
-
Itoh, K.1
Igarashi, K.2
Hayashi, N.3
Nishizawa, M.4
Yamamoto, M.5
-
40
-
-
0032496139
-
Multivalent DNA binding complex generated by small Maf and Bach1 as a possible biochemical basis for beta-globin locus control region complex
-
9565602
-
K.Igarashi, H.Hoshino, A.Muto, N.Suwabe, S.Nishikawa, H.Nakauchi, M.Yamamoto. Multivalent DNA binding complex generated by small Maf and Bach1 as a possible biochemical basis for beta-globin locus control region complex. J Biol Chem 1998; 273:11783-90; PMID:9565602; http://dx.doi.org/10.1074/jbc.273.19.11783
-
(1998)
J Biol Chem
, vol.273
, pp. 11783-11790
-
-
Igarashi, K.1
Hoshino, H.2
Muto, A.3
Suwabe, N.4
Nishikawa, S.5
Nakauchi, H.6
Yamamoto, M.7
-
41
-
-
33845442925
-
Mechanistic studies of the Nrf2-Keap1 signaling pathway
-
17145701
-
D.D.Zhang. Mechanistic studies of the Nrf2-Keap1 signaling pathway. Drug Metab Rev 2006; 38:769-89; PMID:17145701; http://dx.doi.org/10.1080/03602530600971974
-
(2006)
Drug Metab Rev
, vol.38
, pp. 769-789
-
-
Zhang, D.D.1
-
42
-
-
10044228504
-
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex
-
15572695
-
D.D.Zhang, S.C.Lo, J.V.Cross, D.J.Templeton, M.Hannink. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Mol Cell Biol 2004; 24:10941-53; PMID:15572695; http://dx.doi.org/10.1128/MCB.24.24.10941-10953.2004
-
(2004)
Mol Cell Biol
, vol.24
, pp. 10941-10953
-
-
Zhang, D.D.1
Lo, S.C.2
Cross, J.V.3
Templeton, D.J.4
Hannink, M.5
-
43
-
-
84866122688
-
Autophagy modulation as a potential therapeutic target for diverse diseases
-
22935804
-
D.C.Rubinsztein, P.Codogno, B.Levine. Autophagy modulation as a potential therapeutic target for diverse diseases. Nat Rev Drug Dis 2012; 11:709-30; PMID:22935804; http://dx.doi.org/10.1038/nrd3802
-
(2012)
Nat Rev Drug Dis
, vol.11
, pp. 709-730
-
-
Rubinsztein, D.C.1
Codogno, P.2
Levine, B.3
-
44
-
-
84885864424
-
Abeta secretion and plaque formation depend on autophagy
-
24095740
-
P.Nilsson, K.Loganathan, M.Sekiguchi, Y.Matsuba, K.Hui, S.Tsubuki, M.Tanaka, N.Iwata, T.Saito, T.C.Saido. Abeta secretion and plaque formation depend on autophagy. Cell Rep 2013; 5:61-9; PMID:24095740; http://dx.doi.org/10.1016/j.celrep.2013.08.042
-
(2013)
Cell Rep
, vol.5
, pp. 61-69
-
-
Nilsson, P.1
Loganathan, K.2
Sekiguchi, M.3
Matsuba, Y.4
Hui, K.5
Tsubuki, S.6
Tanaka, M.7
Iwata, N.8
Saito, T.9
Saido, T.C.10
-
45
-
-
84865576825
-
Amyloid-beta secretion, generation, and lysosomal sequestration in response to proteasome inhibition: involvement of autophagy
-
22555375
-
L.Agholme, M.Hallbeck, E.Benedikz, J.Marcusson, K.Kagedal. Amyloid-beta secretion, generation, and lysosomal sequestration in response to proteasome inhibition:involvement of autophagy. J Alzheimer's Dis 2012; 31:343-58; PMID:22555375
-
(2012)
J Alzheimer's Dis
, vol.31
, pp. 343-358
-
-
Agholme, L.1
Hallbeck, M.2
Benedikz, E.3
Marcusson, J.4
Kagedal, K.5
-
46
-
-
84870895663
-
Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions
-
22931791
-
S.M.Son, H.Song, J.Byun, K.S.Park, H.C.Jang, Y.J.Park, I.Mook-Jung. Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions. Autophagy 2012; 8:1842-4; PMID:22931791; http://dx.doi.org/10.4161/auto.21861
-
(2012)
Autophagy
, vol.8
, pp. 1842-1844
-
-
Son, S.M.1
Song, H.2
Byun, J.3
Park, K.S.4
Jang, H.C.5
Park, Y.J.6
Mook-Jung, I.7
-
47
-
-
82855181494
-
Macroautophagy-generated increase of lysosomal amyloid beta-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells
-
22108004
-
L.Zheng, A.Terman, M.Hallbeck, N.Dehvari, R.F.Cowburn, E.Benedikz, K.Kågedal, A.Cedazo-Minguez, J.Marcusson. Macroautophagy-generated increase of lysosomal amyloid beta-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells. Autophagy 2011; 7:1528-45; PMID:22108004; http://dx.doi.org/10.4161/auto.7.12.18051
-
(2011)
Autophagy
, vol.7
, pp. 1528-1545
-
-
Zheng, L.1
Terman, A.2
Hallbeck, M.3
Dehvari, N.4
Cowburn, R.F.5
Benedikz, E.6
Kågedal, K.7
Cedazo-Minguez, A.8
Marcusson, J.9
-
48
-
-
26444587508
-
Macroautophagy–a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease
-
16203860
-
W.H.Yu, A.M.Cuervo, A.Kumar, C.M.Peterhoff, S.D.Schmidt, J.H.Lee, P.S.Mohan, M.Mercken, M.R.Farmery, L.O.Tjernberg, et al. Macroautophagy–a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease. J Cell Biol 2005; 171:87-98; PMID:16203860; http://dx.doi.org/10.1083/jcb.200505082
-
(2005)
J Cell Biol
, vol.171
, pp. 87-98
-
-
Yu, W.H.1
Cuervo, A.M.2
Kumar, A.3
Peterhoff, C.M.4
Schmidt, S.D.5
Lee, J.H.6
Mohan, P.S.7
Mercken, M.8
Farmery, M.R.9
Tjernberg, L.O.10
-
49
-
-
4344689871
-
Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease
-
15325590
-
W.H.Yu, A.Kumar, C.Peterhoff, L.Shapiro Kulnane, Y.Uchiyama, B.T.Lamb, A.M.Cuervo, R.A.Nixon. Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities:implications for beta-amyloid peptide over-production and localization in Alzheimer's disease. Int J Biochem Cell Biol 2004; 36:2531-40; PMID:15325590; http://dx.doi.org/10.1016/j.biocel.2004.05.010
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2531-2540
-
-
Yu, W.H.1
Kumar, A.2
Peterhoff, C.3
Shapiro Kulnane, L.4
Uchiyama, Y.5
Lamb, B.T.6
Cuervo, A.M.7
Nixon, R.A.8
-
50
-
-
0037698096
-
Presenilin-1, nicastrin, amyloid precursor protein, and gamma-secretase activity are co-localized in the lysosomal membrane
-
12736250
-
S.H.Pasternak, R.D.Bagshaw, M.Guiral, S.Zhang, C.A.Ackerley, B.J.Pak, J.W.Callahan, D.J.Mahuran. Presenilin-1, nicastrin, amyloid precursor protein, and gamma-secretase activity are co-localized in the lysosomal membrane. J Biol Chem 2003; 278:26687-94; PMID:12736250; http://dx.doi.org/10.1074/jbc.M304009200
-
(2003)
J Biol Chem
, vol.278
, pp. 26687-26694
-
-
Pasternak, S.H.1
Bagshaw, R.D.2
Guiral, M.3
Zhang, S.4
Ackerley, C.A.5
Pak, B.J.6
Callahan, J.W.7
Mahuran, D.J.8
-
51
-
-
84922276427
-
Autophagy-related protein 7 deficiency in amyloid beta (Abeta) precursor protein transgenic mice decreases Abeta in the multivesicular bodies and induces Abeta accumulation in the Golgi
-
25433221
-
P.Nilsson, M.Sekiguchi, T.Akagi, S.Izumi, T.Komori, K.Hui, K.Sörgjerd, M.Tanaka, T.Saito, N.Iwata, et al. Autophagy-related protein 7 deficiency in amyloid beta (Abeta) precursor protein transgenic mice decreases Abeta in the multivesicular bodies and induces Abeta accumulation in the Golgi. Am J Pathol 2015; 185:305-13; PMID:25433221; http://dx.doi.org/10.1016/j.ajpath.2014.10.011
-
(2015)
Am J Pathol
, vol.185
, pp. 305-313
-
-
Nilsson, P.1
Sekiguchi, M.2
Akagi, T.3
Izumi, S.4
Komori, T.5
Hui, K.6
Sörgjerd, K.7
Tanaka, M.8
Saito, T.9
Iwata, N.10
-
52
-
-
84864389698
-
Degradation of tau protein by autophagy and proteasomal pathways
-
22817709
-
Y.Wang, E.Mandelkow. Degradation of tau protein by autophagy and proteasomal pathways. Biochemical Society transactions 2012; 40:644-52; PMID:22817709; http://dx.doi.org/10.1042/BST20120071
-
(2012)
Biochemical Society transactions
, vol.40
, pp. 644-652
-
-
Wang, Y.1
Mandelkow, E.2
-
53
-
-
84877803859
-
mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies
-
23425014
-
A.Caccamo, A.Magri, D.X.Medina, E.V.Wisely, M.F.Lopez-Aranda, A.J.Silva, S.Oddo. mTOR regulates tau phosphorylation and degradation:implications for Alzheimer's disease and other tauopathies. Aging cell 2013; 12:370-80; PMID:23425014; http://dx.doi.org/10.1111/acel.12057
-
(2013)
Aging cell
, vol.12
, pp. 370-380
-
-
Caccamo, A.1
Magri, A.2
Medina, D.X.3
Wisely, E.V.4
Lopez-Aranda, M.F.5
Silva, A.J.6
Oddo, S.7
-
54
-
-
84874607578
-
Rapamycin decreases tau phosphorylation at Ser214 through regulation of cAMP-dependent kinase
-
23357480
-
Y.Liu, Y.Su, J.Wang, S.Sun, T.Wang, X.Qiao, X.Run, H.Li, Z.Liang. Rapamycin decreases tau phosphorylation at Ser214 through regulation of cAMP-dependent kinase. Neurochem Int 2013; 62:458-67; PMID:23357480; http://dx.doi.org/10.1016/j.neuint.2013.01.014
-
(2013)
Neurochem Int
, vol.62
, pp. 458-467
-
-
Liu, Y.1
Su, Y.2
Wang, J.3
Sun, S.4
Wang, T.5
Qiao, X.6
Run, X.7
Li, H.8
Liang, Z.9
-
55
-
-
84877109118
-
Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice
-
23667480
-
S.Ozcelik, G.Fraser, P.Castets, V.Schaeffer, Z.Skachokova, K.Breu, F.Clavaguera, M.Sinnreich, L.Kappos, M.Goedert, et al. Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice. PloS one 2013; 8:e62459; PMID:23667480; http://dx.doi.org/10.1371/journal.pone.0062459
-
(2013)
PloS one
, vol.8
, pp. e62459
-
-
Ozcelik, S.1
Fraser, G.2
Castets, P.3
Schaeffer, V.4
Skachokova, Z.5
Breu, K.6
Clavaguera, F.7
Sinnreich, M.8
Kappos, L.9
Goedert, M.10
-
56
-
-
26444515364
-
Autophagy and its possible roles in nervous system diseases, damage and repair
-
16874045
-
D.C.Rubinsztein, M.DiFiglia, N.Heintz, R.A.Nixon, Z.H.Qin, B.Ravikumar, L.Stefanis, A.Tolkovsky. Autophagy and its possible roles in nervous system diseases, damage and repair. Autophagy 2005; 1:11-22; PMID:16874045; http://dx.doi.org/10.4161/auto.1.1.1513
-
(2005)
Autophagy
, vol.1
, pp. 11-22
-
-
Rubinsztein, D.C.1
DiFiglia, M.2
Heintz, N.3
Nixon, R.A.4
Qin, Z.H.5
Ravikumar, B.6
Stefanis, L.7
Tolkovsky, A.8
-
57
-
-
84929291223
-
Autophagy in neurodegenerative diseases: From pathogenic dysfunction to therapeutic modulation
-
25843774
-
M.Martinez-Vicente. Autophagy in neurodegenerative diseases:From pathogenic dysfunction to therapeutic modulation. Semin Cell Dev Biol 2015; 40:115-26; PMID:25843774; http://dx.doi.org/10.1016/j.semcdb.2015.03.005
-
(2015)
Semin Cell Dev Biol
, vol.40
, pp. 115-126
-
-
Martinez-Vicente, M.1
-
58
-
-
84928662001
-
Autophagosome dynamics in neurodegeneration at a glance
-
25829512
-
Y.C.Wong, E.L.Holzbaur. Autophagosome dynamics in neurodegeneration at a glance. J Cell Sci 2015; 128:1259-67; PMID:25829512; http://dx.doi.org/10.1242/jcs.161216
-
(2015)
J Cell Sci
, vol.128
, pp. 1259-1267
-
-
Wong, Y.C.1
Holzbaur, E.L.2
-
59
-
-
84937020256
-
Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease
-
26062630
-
E.J.Goetzl, A.Boxer, J.B.Schwartz, E.L.Abner, R.C.Petersen, B.L.Miller, D.Kapogiannis. Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease. Neurology 2015; 85:40-7; PMID:26062630; http://dx.doi.org/10.1212/WNL.0000000000001702
-
(2015)
Neurology
, vol.85
, pp. 40-47
-
-
Goetzl, E.J.1
Boxer, A.2
Schwartz, J.B.3
Abner, E.L.4
Petersen, R.C.5
Miller, B.L.6
Kapogiannis, D.7
-
60
-
-
33846073880
-
Expression of Nrf2 in neurodegenerative diseases
-
17204939
-
C.P.Ramsey, C.A.Glass, M.B.Montgomery, K.A.Lindl, G.P.Ritson, L.A.Chia, R.L.Hamilton, C.T.Chu, K.L.Jordan-Sciutto. Expression of Nrf2 in neurodegenerative diseases. J Neuropathol Exp Neurol 2007; 66:75-85; PMID:17204939; http://dx.doi.org/10.1097/nen.0b013e31802d6da9
-
(2007)
J Neuropathol Exp Neurol
, vol.66
, pp. 75-85
-
-
Ramsey, C.P.1
Glass, C.A.2
Montgomery, M.B.3
Lindl, K.A.4
Ritson, G.P.5
Chia, L.A.6
Hamilton, R.L.7
Chu, C.T.8
Jordan-Sciutto, K.L.9
-
61
-
-
0033036818
-
Quinone reductase (NQO1), a sensitive redox indicator, is increased in Alzheimer's disease
-
10714272
-
A.K.Raina, D.J.Templeton, J.C.Deak, G.Perry, M.A.Smith. Quinone reductase (NQO1), a sensitive redox indicator, is increased in Alzheimer's disease. Redox Rep 1999; 4:23-7; PMID:10714272; http://dx.doi.org/10.1179/135100099101534701
-
(1999)
Redox Rep
, vol.4
, pp. 23-27
-
-
Raina, A.K.1
Templeton, D.J.2
Deak, J.C.3
Perry, G.4
Smith, M.A.5
-
62
-
-
0034622230
-
NAD(P)H:quinone oxidoreductase activity is increased in hippocampal pyramidal neurons of patients with Aalzheimer's disease
-
10924765
-
Y.Wang, K.Santa-Cruz, C.DeCarli, J.A.Johnson. NAD(P)H:quinone oxidoreductase activity is increased in hippocampal pyramidal neurons of patients with Aalzheimer's disease. Neurobiol Aging 2000; 21:525-31; PMID:10924765; http://dx.doi.org/10.1016/S0197-4580(00)00114-7
-
(2000)
Neurobiol Aging
, vol.21
, pp. 525-531
-
-
Wang, Y.1
Santa-Cruz, K.2
DeCarli, C.3
Johnson, J.A.4
-
63
-
-
29844450760
-
Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment
-
16399210
-
H.M.Schipper, D.A.Bennett, A.Liberman, J.L.Bienias, J.A.Schneider, J.Kelly, Z.Arvanitakis. Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment. Neurobiol Aging 2006; 27:252-61; PMID:16399210; http://dx.doi.org/10.1016/j.neurobiolaging.2005.01.016
-
(2006)
Neurobiol Aging
, vol.27
, pp. 252-261
-
-
Schipper, H.M.1
Bennett, D.A.2
Liberman, A.3
Bienias, J.L.4
Schneider, J.A.5
Kelly, J.6
Arvanitakis, Z.7
-
64
-
-
84921681202
-
Phosphorylation of serine 349 of p62 in Alzheimer's disease brain
-
24886973
-
K.Tanji, Y.Miki, T.Ozaki, A.Maruyama, H.Yoshida, J.Mimura, T.Matsumiya, F.Mori, T.Imaizumi, K.Itoh, et al. Phosphorylation of serine 349 of p62 in Alzheimer's disease brain. Acta neuropathologica communications 2014; 2:50; PMID:24886973; http://dx.doi.org/10.1186/2051-5960-2-50
-
(2014)
Acta neuropathologica communications
, vol.2
, pp. 50
-
-
Tanji, K.1
Miki, Y.2
Ozaki, T.3
Maruyama, A.4
Yoshida, H.5
Mimura, J.6
Matsumiya, T.7
Mori, F.8
Imaizumi, T.9
Itoh, K.10
-
65
-
-
20044391206
-
Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu
-
15748782
-
N.C.Inestrosa, A.E.Reyes, M.A.Chacon, W.Cerpa, A.Villalon, J.Montiel, G.Merabachvili, R.Aldunate, F.Bozinovic, F.Aboitiz. Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu. Neurobiol Aging 2005; 26:1023-8; PMID:15748782; http://dx.doi.org/10.1016/j.neurobiolaging.2004.09.016
-
(2005)
Neurobiol Aging
, vol.26
, pp. 1023-1028
-
-
Inestrosa, N.C.1
Reyes, A.E.2
Chacon, M.A.3
Cerpa, W.4
Villalon, A.5
Montiel, J.6
Merabachvili, G.7
Aldunate, R.8
Bozinovic, F.9
Aboitiz, F.10
-
66
-
-
77249083614
-
Nrf2-encoding NFE2L2 haplotypes influence disease progression but not risk in Alzheimer's disease and age-related cataract
-
20064547
-
M.von Otter, S.Landgren, S.Nilsson, M.Zetterberg, D.Celojevic, P.Bergstrom, L.Minthon, N.Bogdanovic, N.Andreasen, D.R.Gustafson, et al. Nrf2-encoding NFE2L2 haplotypes influence disease progression but not risk in Alzheimer's disease and age-related cataract. Mechanisms Ageing Dev 2010; 131:105-10; PMID:20064547; http://dx.doi.org/10.1016/j.mad.2009.12.007
-
(2010)
Mechanisms Ageing Dev
, vol.131
, pp. 105-110
-
-
von Otter, M.1
Landgren, S.2
Nilsson, S.3
Zetterberg, M.4
Celojevic, D.5
Bergstrom, P.6
Minthon, L.7
Bogdanovic, N.8
Andreasen, N.9
Gustafson, D.R.10
-
67
-
-
84924050976
-
Genetic associations of Nrf2-encoding NFE2L2 variants with Parkinson's disease - a multicenter study
-
25496089
-
M.von Otter, P.Bergstrom, A.Quattrone, E.V.De Marco, G.Annesi, P.Soderkvist, S.B.Wettinger, M.Drozdzik, M.Bialecka, H.Nissbrandt, et al. Genetic associations of Nrf2-encoding NFE2L2 variants with Parkinson's disease - a multicenter study. BMC Med Genet 2014; 15:131; PMID:25496089; http://dx.doi.org/10.1186/s12881-014-0131-4
-
(2014)
BMC Med Genet
, vol.15
, pp. 131
-
-
von Otter, M.1
Bergstrom, P.2
Quattrone, A.3
De Marco, E.V.4
Annesi, G.5
Soderkvist, P.6
Wettinger, S.B.7
Drozdzik, M.8
Bialecka, M.9
Nissbrandt, H.10
-
68
-
-
84895527015
-
Association of NFE2L2 and KEAP1 haplotypes with amyotrophic lateral sclerosis
-
24102512
-
P.Bergstrom, M.von Otter, S.Nilsson, A.C.Nilsson, M.Nilsson, P.M.Andersen, O.Hammarsten, H.Zetterberg. Association of NFE2L2 and KEAP1 haplotypes with amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener 2014; 15:130-7; PMID:24102512; http://dx.doi.org/10.3109/21678421.2013.839708
-
(2014)
Amyotroph Lateral Scler Frontotemporal Degener
, vol.15
, pp. 130-137
-
-
Bergstrom, P.1
von Otter, M.2
Nilsson, S.3
Nilsson, A.C.4
Nilsson, M.5
Andersen, P.M.6
Hammarsten, O.7
Zetterberg, H.8
-
69
-
-
84870549095
-
Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model
-
23223297
-
L.Gan, M.R.Vargas, D.A.Johnson, J.A.Johnson. Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model. J Neurosci 2012; 32:17775-87; PMID:23223297; http://dx.doi.org/10.1523/JNEUROSCI.3049-12.2012
-
(2012)
J Neurosci
, vol.32
, pp. 17775-17787
-
-
Gan, L.1
Vargas, M.R.2
Johnson, D.A.3
Johnson, J.A.4
-
70
-
-
84978394291
-
Repurposing the NRF2 activator dimethyl fumarate as therapy against synucleinopathy in Parkinson's disease
-
I.Lastres Becker, A.J.Garcia-Yague, R.H.Scannevin, M.J.Casarejos, S.Kugler, A.Rabano, et al. Repurposing the NRF2 activator dimethyl fumarate as therapy against synucleinopathy in Parkinson's disease. Antioxid Redox Signal 2016; 25(2):61-77
-
(2016)
Antioxid Redox Signal
, vol.25
, Issue.2
, pp. 61-77
-
-
Lastres Becker, I.1
Garcia-Yague, A.J.2
Scannevin, R.H.3
Casarejos, M.J.4
Kugler, S.5
Rabano, A.6
-
71
-
-
84992215855
-
A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy
-
26962150
-
L.C.Bott, N.M.Badders, K.L.Chen, G.G.Harmison, E.Bautista, C.C.Shih, M.Katsuno, G.Sobue, J.P.Taylor, N.P.Dantuma, et al. A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy. Hum Mol Genet 2016; PMID:26962150; http://dx.doi.org/10.1093/hmg/ddw073
-
(2016)
Hum Mol Genet
-
-
Bott, L.C.1
Badders, N.M.2
Chen, K.L.3
Harmison, G.G.4
Bautista, E.5
Shih, C.C.6
Katsuno, M.7
Sobue, G.8
Taylor, J.P.9
Dantuma, N.P.10
-
72
-
-
13644268449
-
Changed conformation of mutant Tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of Tau-4R/2N transgenic mice
-
15509565
-
D.Terwel, R.Lasrado, J.Snauwaert, E.Vandeweert, C.Van Haesendonck, P.Borghgraef, F.Van Leuven. Changed conformation of mutant Tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of Tau-4R/2N transgenic mice. J Biol Chem 2005; 280:3963-73; PMID:15509565; http://dx.doi.org/10.1074/jbc.M409876200
-
(2005)
J Biol Chem
, vol.280
, pp. 3963-3973
-
-
Terwel, D.1
Lasrado, R.2
Snauwaert, J.3
Vandeweert, E.4
Van Haesendonck, C.5
Borghgraef, P.6
Van Leuven, F.7
-
73
-
-
0033525520
-
Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain
-
10037741
-
D.Moechars, I.Dewachter, K.Lorent, D.Reverse, V.Baekelandt, A.Naidu, I.Tesseur, K.Spittaels, C.V.Haute, F.Checler, et al. Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain. J Biol Chem 1999; 274:6483-92; PMID:10037741; http://dx.doi.org/10.1074/jbc.274.10.6483
-
(1999)
J Biol Chem
, vol.274
, pp. 6483-6492
-
-
Moechars, D.1
Dewachter, I.2
Lorent, K.3
Reverse, D.4
Baekelandt, V.5
Naidu, A.6
Tesseur, I.7
Spittaels, K.8
Haute, C.V.9
Checler, F.10
-
74
-
-
84892773204
-
Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis
-
24277722
-
I.Lastres-Becker, N.G.Innamorato, T.Jaworski, A.Rabano, S.Kugler, F.Van Leuven, A.Cuadrado. Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis. Brain 2014; 137:78-91; PMID:24277722; http://dx.doi.org/10.1093/brain/awt323
-
(2014)
Brain
, vol.137
, pp. 78-91
-
-
Lastres-Becker, I.1
Innamorato, N.G.2
Jaworski, T.3
Rabano, A.4
Kugler, S.5
Van Leuven, F.6
Cuadrado, A.7
-
75
-
-
84855458875
-
Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3
-
22142471
-
A.I.Rojo, O.N.Medina-Campos, P.Rada, A.Zuniga-Toala, A.Lopez-Gazcon, S.Espada, J.Pedraza-Chaverri, A.Cuadrado. Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability:Role of glycogen synthase kinase-3. Free Radic Biol Med 2012; 52:473-87; PMID:22142471; http://dx.doi.org/10.1016/j.freeradbiomed.2011.11.003
-
(2012)
Free Radic Biol Med
, vol.52
, pp. 473-487
-
-
Rojo, A.I.1
Medina-Campos, O.N.2
Rada, P.3
Zuniga-Toala, A.4
Lopez-Gazcon, A.5
Espada, S.6
Pedraza-Chaverri, J.7
Cuadrado, A.8
-
76
-
-
77749339881
-
Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease
-
19908287
-
A.I.Rojo, N.G.Innamorato, A.M.Martin-Moreno, M.L.De Ceballos, M.Yamamoto, A.Cuadrado. Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease. Glia 2010; 58:588-98; PMID:19908287; http://dx.doi.org/10.1002/glia.20947
-
(2010)
Glia
, vol.58
, pp. 588-598
-
-
Rojo, A.I.1
Innamorato, N.G.2
Martin-Moreno, A.M.3
De Ceballos, M.L.4
Yamamoto, M.5
Cuadrado, A.6
|