-
1
-
-
0028061444
-
Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region
-
P. Moi, K. Chan, I. Asunis, A. Cao, and Y.W. Kan Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region Proc Natl Acad Sci USA 91 1994 9926 9930
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9926-9930
-
-
Moi, P.1
Chan, K.2
Asunis, I.3
Cao, A.4
Kan, Y.W.5
-
2
-
-
0029043995
-
Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins
-
K. Itoh, K. Igarashi, N. Hayashi, M. Nishizawa, and M. Yamamoto Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins Mol Cell Biol 15 1995 4184 4193
-
(1995)
Mol Cell Biol
, vol.15
, pp. 4184-4193
-
-
Itoh, K.1
Igarashi, K.2
Hayashi, N.3
Nishizawa, M.4
Yamamoto, M.5
-
3
-
-
0032827002
-
Regulatory mechanisms of cellular response to oxidative stress
-
K. Itoh, T. Ishii, N. Wakabayashi, and M. Yamamoto Regulatory mechanisms of cellular response to oxidative stress Free Radic Res 31 1999 319 324
-
(1999)
Free Radic Res
, vol.31
, pp. 319-324
-
-
Itoh, K.1
Ishii, T.2
Wakabayashi, N.3
Yamamoto, M.4
-
4
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
A.T. Dinkova-Kostova, W.D. Holtzclaw, R.N. Cole, K. Itoh, N. Wakabayashi, Y. Katoh, M. Yamamoto, and P. Talalay Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants Proc Natl Acad Sci U S A 99 2002 11908 11913
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
Yamamoto, M.7
Talalay, P.8
-
5
-
-
0242580049
-
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
-
D.D. Zhang, and M. Hannink Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress Mol Cell Biol 23 2003 8137 8151
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8137-8151
-
-
Zhang, D.D.1
Hannink, M.2
-
6
-
-
79952256187
-
SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner
-
P. Rada, A.I. Rojo, S. Chowdhry, M. McMahon, J.D. Hayes, and A. Cuadrado SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner Mol Cell Biol 31 2011 1121 1133
-
(2011)
Mol Cell Biol
, vol.31
, pp. 1121-1133
-
-
Rada, P.1
Rojo, A.I.2
Chowdhry, S.3
McMahon, M.4
Hayes, J.D.5
Cuadrado, A.6
-
7
-
-
84881476323
-
Nrf2 is controlled by two distinct beta-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity
-
S. Chowdhry, Y. Zhang, M. McMahon, C. Sutherland, A. Cuadrado, and J.D. Hayes Nrf2 is controlled by two distinct beta-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity Oncogene 32 2013 3765 3781
-
(2013)
Oncogene
, vol.32
, pp. 3765-3781
-
-
Chowdhry, S.1
Zhang, Y.2
McMahon, M.3
Sutherland, C.4
Cuadrado, A.5
Hayes, J.D.6
-
8
-
-
84898874270
-
Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis
-
T. Wu, F. Zhao, B. Gao, C. Tan, N. Yagishita, T. Nakajima, P.K. Wong, E. Chapman, D. Fang, and D.D. Zhang Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis Genes Dev 28 2014 708 722
-
(2014)
Genes Dev
, vol.28
, pp. 708-722
-
-
Wu, T.1
Zhao, F.2
Gao, B.3
Tan, C.4
Yagishita, N.5
Nakajima, T.6
Wong, P.K.7
Chapman, E.8
Fang, D.9
Zhang, D.D.10
-
9
-
-
36249025723
-
Autophagy: Process and function
-
N. Mizushima Autophagy: process and function Genes Dev 21 2007 2861 2873
-
(2007)
Genes Dev
, vol.21
, pp. 2861-2873
-
-
Mizushima, N.1
-
10
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
B. Levine, and G. Kroemer Autophagy in the pathogenesis of disease Cell 132 2008 27 42
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
12
-
-
62949091373
-
Autophagy: A lysosomal degradation pathway with a central role in health and disease
-
E.L. Eskelinen, and P. Saftig Autophagy: a lysosomal degradation pathway with a central role in health and disease Biochim Biophys Acta 1793 2009 664 673
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 664-673
-
-
Eskelinen, E.L.1
Saftig, P.2
-
13
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
N. Mizushima, B. Levine, A.M. Cuervo, and D.J. Klionsky Autophagy fights disease through cellular self-digestion Nature 451 2008 1069 1075
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
14
-
-
65249187333
-
Enhancing immunity through autophagy
-
C. Munz Enhancing immunity through autophagy Annual review of immunology 27 2009 423 449
-
(2009)
Annual Review of Immunology
, vol.27
, pp. 423-449
-
-
Munz, C.1
-
15
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
K. Degenhardt, R. Mathew, B. Beaudoin, K. Bray, D. Anderson, G. Chen, C. Mukherjee, Y. Shi, C. Gelinas, Y. Fan, D.A. Nelson, S. Jin, and E. White Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis Cancer Cell 10 2006 51 64
-
(2006)
Cancer Cell
, vol.10
, pp. 51-64
-
-
Degenhardt, K.1
Mathew, R.2
Beaudoin, B.3
Bray, K.4
Anderson, D.5
Chen, G.6
Mukherjee, C.7
Shi, Y.8
Gelinas, C.9
Fan, Y.10
Nelson, D.A.11
Jin, S.12
White, E.13
-
16
-
-
84943199868
-
Cell death by autophagy: Emerging molecular mechanisms and implications for cancer therapy
-
S. Fulda, and D. Kogel Cell death by autophagy: emerging molecular mechanisms and implications for cancer therapy Oncogene 2015
-
(2015)
Oncogene
-
-
Fulda, S.1
Kogel, D.2
-
17
-
-
46949099638
-
Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2
-
X.J. Wang, Z. Sun, N.F. Villeneuve, S. Zhang, F. Zhao, Y. Li, W. Chen, X. Yi, W. Zheng, G.T. Wondrak, P.K. Wong, and D.D. Zhang Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2 Carcinogenesis 29 2008 1235 1243
-
(2008)
Carcinogenesis
, vol.29
, pp. 1235-1243
-
-
Wang, X.J.1
Sun, Z.2
Villeneuve, N.F.3
Zhang, S.4
Zhao, F.5
Li, Y.6
Chen, W.7
Yi, X.8
Zheng, W.9
Wondrak, G.T.10
Wong, P.K.11
Zhang, D.D.12
-
18
-
-
77649265091
-
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
-
M. Komatsu, H. Kurokawa, S. Waguri, K. Taguchi, A. Kobayashi, Y. Ichimura, Y.S. Sou, I. Ueno, A. Sakamoto, K.I. Tong, M. Kim, Y. Nishito, S. Iemura, T. Natsume, T. Ueno, E. Kominami, H. Motohashi, K. Tanaka, and M. Yamamoto The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 Nat Cell Biol 12 2010 213 223
-
(2010)
Nat Cell Biol
, vol.12
, pp. 213-223
-
-
Komatsu, M.1
Kurokawa, H.2
Waguri, S.3
Taguchi, K.4
Kobayashi, A.5
Ichimura, Y.6
Sou, Y.S.7
Ueno, I.8
Sakamoto, A.9
Tong, K.I.10
Kim, M.11
Nishito, Y.12
Iemura, S.13
Natsume, T.14
Ueno, T.15
Kominami, E.16
Motohashi, H.17
Tanaka, K.18
Yamamoto, M.19
-
19
-
-
77953366801
-
A noncanonical mechanism of Nrf2 activation by autophagy deficiency: Direct interaction between Keap1 and p62
-
A. Lau, X.J. Wang, F. Zhao, N.F. Villeneuve, T. Wu, T. Jiang, Z. Sun, E. White, and D.D. Zhang A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62 Mol Cell Biol 30 2010 3275 3285
-
(2010)
Mol Cell Biol
, vol.30
, pp. 3275-3285
-
-
Lau, A.1
Wang, X.J.2
Zhao, F.3
Villeneuve, N.F.4
Wu, T.5
Jiang, T.6
Sun, Z.7
White, E.8
Zhang, D.D.9
-
20
-
-
77954599053
-
P62/SQSTM1 is a target gene for transcription factor Nrf2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
-
A. Jain, T. Lamark, E. Sjottem, K.B. Larsen, J.A. Awuh, A. Overvatn, M. McMahon, J.D. Hayes, and T. Johansen p62/SQSTM1 is a target gene for transcription factor Nrf2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription The Journal of biological chemistry 285 2010 22576 22591
-
(2010)
The Journal of Biological Chemistry
, vol.285
, pp. 22576-22591
-
-
Jain, A.1
Lamark, T.2
Sjottem, E.3
Larsen, K.B.4
Awuh, J.A.5
Overvatn, A.6
McMahon, M.7
Hayes, J.D.8
Johansen, T.9
-
21
-
-
77955352128
-
Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy
-
W. Fan, Z. Tang, D. Chen, D. Moughon, X. Ding, S. Chen, M. Zhu, and Q. Zhong Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy Autophagy 6 2010 614 621
-
(2010)
Autophagy
, vol.6
, pp. 614-621
-
-
Fan, W.1
Tang, Z.2
Chen, D.3
Moughon, D.4
Ding, X.5
Chen, S.6
Zhu, M.7
Zhong, Q.8
-
22
-
-
77952781968
-
Physical and functional interaction of sequestosome 1 with Keap1 regulates the Keap1-Nrf2 cell defense pathway
-
I.M. Copple, A. Lister, A.D. Obeng, N.R. Kitteringham, R.E. Jenkins, R. Layfield, B.J. Foster, C.E. Goldring, and B.K. Park Physical and functional interaction of sequestosome 1 with Keap1 regulates the Keap1-Nrf2 cell defense pathway The Journal of biological chemistry 285 2010 16782 16788
-
(2010)
The Journal of Biological Chemistry
, vol.285
, pp. 16782-16788
-
-
Copple, I.M.1
Lister, A.2
Obeng, A.D.3
Kitteringham, N.R.4
Jenkins, R.E.5
Layfield, R.6
Foster, B.J.7
Goldring, C.E.8
Park, B.K.9
-
23
-
-
0029894586
-
Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain
-
I. Joung, J.L. Strominger, and J. Shin Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain Proc Natl Acad Sci U S A 93 1996 5991 5995
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5991-5995
-
-
Joung, I.1
Strominger, J.L.2
Shin, J.3
-
24
-
-
0036094026
-
Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone
-
N. Laurin, J.P. Brown, J. Morissette, and V. Raymond Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone Am J Hum Genet 70 2002 1582 1588
-
(2002)
Am J Hum Genet
, vol.70
, pp. 1582-1588
-
-
Laurin, N.1
Brown, J.P.2
Morissette, J.3
Raymond, V.4
-
25
-
-
0037108914
-
Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease
-
L.J. Hocking, G.J. Lucas, A. Daroszewska, J. Mangion, M. Olavesen, T. Cundy, G.C. Nicholson, L. Ward, S.T. Bennett, W. Wuyts, W. Van Hul, and S.H. Ralston Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease Hum Mol Genet 11 2002 2735 2739
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2735-2739
-
-
Hocking, L.J.1
Lucas, G.J.2
Daroszewska, A.3
Mangion, J.4
Olavesen, M.5
Cundy, T.6
Nicholson, G.C.7
Ward, L.8
Bennett, S.T.9
Wuyts, W.10
Van Hul, W.11
Ralston, S.H.12
-
26
-
-
36849089101
-
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
-
M. Komatsu, S. Waguri, M. Koike, Y.S. Sou, T. Ueno, T. Hara, N. Mizushima, J. Iwata, J. Ezaki, S. Murata, J. Hamazaki, Y. Nishito, S. Iemura, T. Natsume, T. Yanagawa, J. Uwayama, E. Warabi, H. Yoshida, T. Ishii, A. Kobayashi, M. Yamamoto, Z. Yue, Y. Uchiyama, E. Kominami, and K. Tanaka Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice Cell 131 2007 1149 1163
-
(2007)
Cell
, vol.131
, pp. 1149-1163
-
-
Komatsu, M.1
Waguri, S.2
Koike, M.3
Sou, Y.S.4
Ueno, T.5
Hara, T.6
Mizushima, N.7
Iwata, J.8
Ezaki, J.9
Murata, S.10
Hamazaki, J.11
Nishito, Y.12
Iemura, S.13
Natsume, T.14
Yanagawa, T.15
Uwayama, J.16
Warabi, E.17
Yoshida, H.18
Ishii, T.19
Kobayashi, A.20
Yamamoto, M.21
Yue, Z.22
Uchiyama, Y.23
Kominami, E.24
Tanaka, K.25
more..
-
27
-
-
34247594896
-
A genomic screen for activators of the antioxidant response element
-
Y. Liu, J.T. Kern, J.R. Walker, J.A. Johnson, P.G. Schultz, and H. Luesch A genomic screen for activators of the antioxidant response element Proc Natl Acad Sci U S A 104 2007 5205 5210
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 5205-5210
-
-
Liu, Y.1
Kern, J.T.2
Walker, J.R.3
Johnson, J.A.4
Schultz, P.G.5
Luesch, H.6
-
28
-
-
84865287281
-
Keap1 degradation by autophagy for the maintenance of redox homeostasis
-
K. Taguchi, N. Fujikawa, M. Komatsu, T. Ishii, M. Unno, T. Akaike, H. Motohashi, and M. Yamamoto Keap1 degradation by autophagy for the maintenance of redox homeostasis Proc Natl Acad Sci U S A 109 2012 13561 13566
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 13561-13566
-
-
Taguchi, K.1
Fujikawa, N.2
Komatsu, M.3
Ishii, T.4
Unno, M.5
Akaike, T.6
Motohashi, H.7
Yamamoto, M.8
-
29
-
-
33750613056
-
Two-site substrate recognition model for the Keap1-Nrf2 system: A hinge and latch mechanism
-
K.I. Tong, A. Kobayashi, F. Katsuoka, and M. Yamamoto Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism Biol Chem 387 2006 1311 1320
-
(2006)
Biol Chem
, vol.387
, pp. 1311-1320
-
-
Tong, K.I.1
Kobayashi, A.2
Katsuoka, F.3
Yamamoto, M.4
-
30
-
-
33344463325
-
Keap1 recruits Neh2 through binding to ETGE and DLG motifs: Characterization of the two-site molecular recognition model
-
K.I. Tong, Y. Katoh, H. Kusunoki, K. Itoh, T. Tanaka, and M. Yamamoto Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model Mol Cell Biol 26 2006 2887 2900
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2887-2900
-
-
Tong, K.I.1
Katoh, Y.2
Kusunoki, H.3
Itoh, K.4
Tanaka, T.5
Yamamoto, M.6
-
31
-
-
35648970026
-
Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response
-
K.I. Tong, B. Padmanabhan, A. Kobayashi, C. Shang, Y. Hirotsu, S. Yokoyama, and M. Yamamoto Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response Mol Cell Biol 27 2007 7511 7521
-
(2007)
Mol Cell Biol
, vol.27
, pp. 7511-7521
-
-
Tong, K.I.1
Padmanabhan, B.2
Kobayashi, A.3
Shang, C.4
Hirotsu, Y.5
Yokoyama, S.6
Yamamoto, M.7
-
32
-
-
33747728194
-
Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: A two-site interaction model for the Nrf2-Keap1 complex
-
M. McMahon, N. Thomas, K. Itoh, M. Yamamoto, and J.D. Hayes Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex The Journal of biological chemistry 281 2006 24756 24768
-
(2006)
The Journal of Biological Chemistry
, vol.281
, pp. 24756-24768
-
-
McMahon, M.1
Thomas, N.2
Itoh, K.3
Yamamoto, M.4
Hayes, J.D.5
-
33
-
-
84884338770
-
Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex
-
L. Baird, D. Lleres, S. Swift, and A.T. Dinkova-Kostova Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex Proc Natl Acad Sci U S A 110 2013 15259 15264
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 15259-15264
-
-
Baird, L.1
Lleres, D.2
Swift, S.3
Dinkova-Kostova, A.T.4
-
34
-
-
84883830467
-
Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy
-
Y. Ichimura, S. Waguri, Y.S. Sou, S. Kageyama, J. Hasegawa, R. Ishimura, T. Saito, Y. Yang, T. Kouno, T. Fukutomi, T. Hoshii, A. Hirao, K. Takagi, T. Mizushima, H. Motohashi, M.S. Lee, T. Yoshimori, K. Tanaka, M. Yamamoto, and M. Komatsu Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy Mol Cell 51 2013 618 631
-
(2013)
Mol Cell
, vol.51
, pp. 618-631
-
-
Ichimura, Y.1
Waguri, S.2
Sou, Y.S.3
Kageyama, S.4
Hasegawa, J.5
Ishimura, R.6
Saito, T.7
Yang, Y.8
Kouno, T.9
Fukutomi, T.10
Hoshii, T.11
Hirao, A.12
Takagi, K.13
Mizushima, T.14
Motohashi, H.15
Lee, M.S.16
Yoshimori, T.17
Tanaka, K.18
Yamamoto, M.19
Komatsu, M.20
more..
-
35
-
-
84872137966
-
Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage
-
S.H. Bae, S.H. Sung, S.Y. Oh, J.M. Lim, S.K. Lee, Y.N. Park, H.E. Lee, D. Kang, and S.G. Rhee Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage Cell Metab 17 2013 73 84
-
(2013)
Cell Metab
, vol.17
, pp. 73-84
-
-
Bae, S.H.1
Sung, S.H.2
Oh, S.Y.3
Lim, J.M.4
Lee, S.K.5
Park, Y.N.6
Lee, H.E.7
Kang, D.8
Rhee, S.G.9
-
36
-
-
84908371000
-
Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1
-
S.H. Ro, I.A. Semple, H. Park, H. Park, H.W. Park, M. Kim, J.S. Kim, and J.H. Lee Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1 FEBS J 281 2014 3816 3827
-
(2014)
FEBS J
, vol.281
, pp. 3816-3827
-
-
Ro, S.H.1
Semple, I.A.2
Park, H.3
Park, H.4
Park, H.W.5
Kim, M.6
Kim, J.S.7
Lee, J.H.8
-
37
-
-
84906247013
-
Incorporating epigenetic data into the risk assessment process for the toxic metals arsenic, cadmium, chromium, lead, and mercury: Strategies and challenges
-
P.D. Ray, A. Yosim, and R.C. Fry Incorporating epigenetic data into the risk assessment process for the toxic metals arsenic, cadmium, chromium, lead, and mercury: strategies and challenges Frontiers in genetics 5 2014 201
-
(2014)
Frontiers in Genetics
, vol.5
, pp. 201
-
-
Ray, P.D.1
Yosim, A.2
Fry, R.C.3
-
38
-
-
84883746936
-
In utero and early life arsenic exposure in relation to long-term health and disease
-
S.F. Farzan, M.R. Karagas, and Y. Chen In utero and early life arsenic exposure in relation to long-term health and disease Toxicol Appl Pharmacol 272 2013 384 390
-
(2013)
Toxicol Appl Pharmacol
, vol.272
, pp. 384-390
-
-
Farzan, S.F.1
Karagas, M.R.2
Chen, Y.3
-
39
-
-
34547586639
-
A review of the epidemiologic literature on the role of environmental arsenic exposure and cardiovascular diseases
-
C.H. Wang, C.K. Hsiao, C.L. Chen, L.I. Hsu, H.Y. Chiou, S.Y. Chen, Y.M. Hsueh, M.M. Wu, and C.J. Chen A review of the epidemiologic literature on the role of environmental arsenic exposure and cardiovascular diseases Toxicol Appl Pharmacol 222 2007 315 326
-
(2007)
Toxicol Appl Pharmacol
, vol.222
, pp. 315-326
-
-
Wang, C.H.1
Hsiao, C.K.2
Chen, C.L.3
Hsu, L.I.4
Chiou, H.Y.5
Chen, S.Y.6
Hsueh, Y.M.7
Wu, M.M.8
Chen, C.J.9
-
40
-
-
84870950702
-
Arsenic and human health: Epidemiologic progress and public health implications
-
M. Argos, H. Ahsan, and J.H. Graziano Arsenic and human health: epidemiologic progress and public health implications Rev Environ Health 27 2012 191 195
-
(2012)
Rev Environ Health
, vol.27
, pp. 191-195
-
-
Argos, M.1
Ahsan, H.2
Graziano, J.H.3
-
41
-
-
84864884168
-
Evaluation of the association between arsenic and diabetes: A National Toxicology Program workshop review
-
E.A. Maull, H. Ahsan, J. Edwards, M.P. Longnecker, A. Navas-Acien, J. Pi, E.K. Silbergeld, M. Styblo, C.H. Tseng, K.A. Thayer, and D. Loomis Evaluation of the association between arsenic and diabetes: a National Toxicology Program workshop review Environ Health Perspect 120 2012 1658 1670
-
(2012)
Environ Health Perspect
, vol.120
, pp. 1658-1670
-
-
Maull, E.A.1
Ahsan, H.2
Edwards, J.3
Longnecker, M.P.4
Navas-Acien, A.5
Pi, J.6
Silbergeld, E.K.7
Styblo, M.8
Tseng, C.H.9
Thayer, K.A.10
Loomis, D.11
-
42
-
-
33746892695
-
Arsenic exposure is associated with decreased DNA repair in vitro and in individuals exposed to drinking water arsenic
-
A.S. Andrew, J.L. Burgess, M.M. Meza, E. Demidenko, M.G. Waugh, J.W. Hamilton, and M.R. Karagas Arsenic exposure is associated with decreased DNA repair in vitro and in individuals exposed to drinking water arsenic Environ Health Perspect 114 2006 1193 1198
-
(2006)
Environ Health Perspect
, vol.114
, pp. 1193-1198
-
-
Andrew, A.S.1
Burgess, J.L.2
Meza, M.M.3
Demidenko, E.4
Waugh, M.G.5
Hamilton, J.W.6
Karagas, M.R.7
-
43
-
-
0037431439
-
Decreased DNA repair gene expression among individuals exposed to arsenic in United States drinking water. International journal of cancer
-
A.S. Andrew, M.R. Karagas, and J.W. Hamilton Decreased DNA repair gene expression among individuals exposed to arsenic in United States drinking water. International journal of cancer Journal international du cancer 104 2003 263 268
-
(2003)
Journal International du Cancer
, vol.104
, pp. 263-268
-
-
Andrew, A.S.1
Karagas, M.R.2
Hamilton, J.W.3
-
44
-
-
84898032934
-
Toxicological properties of the thiolated inorganic arsenic and arsenosugar metabolite thio-dimethylarsinic acid in human bladder cells
-
F. Ebert, L. Leffers, T. Weber, S. Berndt, A. Mangerich, S. Beneke, A. Burkle, and T. Schwerdtle Toxicological properties of the thiolated inorganic arsenic and arsenosugar metabolite thio-dimethylarsinic acid in human bladder cells J Trace Elem Med Biol 28 2014 138 146
-
(2014)
J Trace Elem Med Biol
, vol.28
, pp. 138-146
-
-
Ebert, F.1
Leffers, L.2
Weber, T.3
Berndt, S.4
Mangerich, A.5
Beneke, S.6
Burkle, A.7
Schwerdtle, T.8
-
45
-
-
84902303699
-
Critical role of cellular glutathione homeostasis for trivalent inorganic arsenite-induced oxidative damage in human bronchial epithelial cells
-
X. Jiang, C. Chen, Y. Liu, P. Zhang, and Z. Zhang Critical role of cellular glutathione homeostasis for trivalent inorganic arsenite-induced oxidative damage in human bronchial epithelial cells Mutat Res Genet Toxicol Environ Mutagen 770 2014 35 45
-
(2014)
Mutat Res Genet Toxicol Environ Mutagen
, vol.770
, pp. 35-45
-
-
Jiang, X.1
Chen, C.2
Liu, Y.3
Zhang, P.4
Zhang, Z.5
-
46
-
-
84887473604
-
Inorganic arsenic induces apoptosis through downregulation of Ube2d genes and p53 accumulation in rat proximal tubular cells
-
M. Tokumoto, J.Y. Lee, Y. Fujiwara, M. Uchiyama, and M. Satoh Inorganic arsenic induces apoptosis through downregulation of Ube2d genes and p53 accumulation in rat proximal tubular cells J Toxicol Sci 38 2013 815 820
-
(2013)
J Toxicol Sci
, vol.38
, pp. 815-820
-
-
Tokumoto, M.1
Lee, J.Y.2
Fujiwara, Y.3
Uchiyama, M.4
Satoh, M.5
-
48
-
-
84878963658
-
Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner
-
A. Lau, Y. Zheng, S. Tao, H. Wang, S.A. Whitman, E. White, and D.D. Zhang Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner Mol Cell Biol 33 2013 2436 2446
-
(2013)
Mol Cell Biol
, vol.33
, pp. 2436-2446
-
-
Lau, A.1
Zheng, Y.2
Tao, S.3
Wang, H.4
Whitman, S.A.5
White, E.6
Zhang, D.D.7
-
49
-
-
46749152185
-
Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: Enhanced Keap1-Cul3 interaction
-
X.J. Wang, Z. Sun, W. Chen, Y. Li, N.F. Villeneuve, and D.D. Zhang Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction Toxicol Appl Pharmacol 230 2008 383 389
-
(2008)
Toxicol Appl Pharmacol
, vol.230
, pp. 383-389
-
-
Wang, X.J.1
Sun, Z.2
Chen, W.3
Li, Y.4
Villeneuve, N.F.5
Zhang, D.D.6
-
50
-
-
84907821973
-
Nrf2/p62 signaling in apoptosis resistance and its role in cadmium-induced carcinogenesis
-
Y.O. Son, P. Pratheeshkumar, R.V. Roy, J.A. Hitron, L. Wang, Z. Zhang, and X. Shi Nrf2/p62 signaling in apoptosis resistance and its role in cadmium-induced carcinogenesis The Journal of biological chemistry 289 2014 28660 28675
-
(2014)
The Journal of Biological Chemistry
, vol.289
, pp. 28660-28675
-
-
Son, Y.O.1
Pratheeshkumar, P.2
Roy, R.V.3
Hitron, J.A.4
Wang, L.5
Zhang, Z.6
Shi, X.7
-
51
-
-
84883263432
-
Distinct effects of methamphetamine on autophagy-lysosome and ubiquitin-proteasome systems in HL-1 cultured mouse atrial cardiomyocytes
-
I. Funakoshi-Hirose, T. Aki, K. Unuma, T. Funakoshi, K. Noritake, and K. Uemura Distinct effects of methamphetamine on autophagy-lysosome and ubiquitin-proteasome systems in HL-1 cultured mouse atrial cardiomyocytes Toxicology 312 2013 74 82
-
(2013)
Toxicology
, vol.312
, pp. 74-82
-
-
Funakoshi-Hirose, I.1
Aki, T.2
Unuma, K.3
Funakoshi, T.4
Noritake, K.5
Uemura, K.6
-
52
-
-
84908387127
-
Oxidative stress-dependent activation of the eIF2alpha-ATFr unfolded protein response branch by skin sensitizer 1-fluoro-2,4-dinitrobenzene modulates dendritic-like cell maturation and inflammatory status in a biphasic manner
-
A. Luis, J.D. Martins, A. Silva, I. Ferreira, M.T. Cruz, and B.M. Neves Oxidative stress-dependent activation of the eIF2alpha-ATFr unfolded protein response branch by skin sensitizer 1-fluoro-2,4-dinitrobenzene modulates dendritic-like cell maturation and inflammatory status in a biphasic manner Free Radic Biol Med 77 2014 217 229
-
(2014)
Free Radic Biol Med
, vol.77
, pp. 217-229
-
-
Luis, A.1
Martins, J.D.2
Silva, A.3
Ferreira, I.4
Cruz, M.T.5
Neves, B.M.6
-
53
-
-
84892817921
-
A somatic mutation of the Keap1 gene in malignant melanoma is involved in aberrant Nrf2 activation and an increase in intrinsic drug resistance
-
S. Miura, M. Shibazaki, S. Kasai, S. Yasuhira, A. Watanabe, T. Inoue, Y. Kageshita, K. Tsunoda, K. Takahashi, T. Akasaka, T. Masuda, and C. Maesawa A somatic mutation of the Keap1 gene in malignant melanoma is involved in aberrant Nrf2 activation and an increase in intrinsic drug resistance J Invest Dermatol 134 2014 553 556
-
(2014)
J Invest Dermatol
, vol.134
, pp. 553-556
-
-
Miura, S.1
Shibazaki, M.2
Kasai, S.3
Yasuhira, S.4
Watanabe, A.5
Inoue, T.6
Kageshita, Y.7
Tsunoda, K.8
Takahashi, K.9
Akasaka, T.10
Masuda, T.11
Maesawa, C.12
-
54
-
-
84880967722
-
Integrated molecular analysis of clear-cell renal cell carcinoma
-
Y. Sato, T. Yoshizato, Y. Shiraishi, S. Maekawa, Y. Okuno, T. Kamura, T. Shimamura, A. Sato-Otsubo, G. Nagae, H. Suzuki, Y. Nagata, K. Yoshida, A. Kon, Y. Suzuki, K. Chiba, H. Tanaka, A. Niida, A. Fujimoto, T. Tsunoda, T. Morikawa, D. Maeda, H. Kume, S. Sugano, M. Fukayama, H. Aburatani, M. Sanada, S. Miyano, Y. Homma, and S. Ogawa Integrated molecular analysis of clear-cell renal cell carcinoma Nat Genet 45 2013 860 867
-
(2013)
Nat Genet
, vol.45
, pp. 860-867
-
-
Sato, Y.1
Yoshizato, T.2
Shiraishi, Y.3
Maekawa, S.4
Okuno, Y.5
Kamura, T.6
Shimamura, T.7
Sato-Otsubo, A.8
Nagae, G.9
Suzuki, H.10
Nagata, Y.11
Yoshida, K.12
Kon, A.13
Suzuki, Y.14
Chiba, K.15
Tanaka, H.16
Niida, A.17
Fujimoto, A.18
Tsunoda, T.19
Morikawa, T.20
Maeda, D.21
Kume, H.22
Sugano, S.23
Fukayama, M.24
Aburatani, H.25
Sanada, M.26
Miyano, S.27
Homma, Y.28
Ogawa, S.29
more..
-
55
-
-
84887022334
-
Identification of driver genes in hepatocellular carcinoma by exome sequencing
-
S.P. Cleary, W.R. Jeck, X. Zhao, K. Chen, S.R. Selitsky, G.L. Savich, T.X. Tan, M.C. Wu, G. Getz, M.S. Lawrence, J.S. Parker, J. Li, S. Powers, H. Kim, S. Fischer, M. Guindi, A. Ghanekar, and D.Y. Chiang Identification of driver genes in hepatocellular carcinoma by exome sequencing Hepatology 58 2013 1693 1702
-
(2013)
Hepatology
, vol.58
, pp. 1693-1702
-
-
Cleary, S.P.1
Jeck, W.R.2
Zhao, X.3
Chen, K.4
Selitsky, S.R.5
Savich, G.L.6
Tan, T.X.7
Wu, M.C.8
Getz, G.9
Lawrence, M.S.10
Parker, J.S.11
Li, J.12
Powers, S.13
Kim, H.14
Fischer, S.15
Guindi, M.16
Ghanekar, A.17
Chiang, D.Y.18
-
56
-
-
33750885385
-
Dysfunctional Keap1-Nrf2 interaction in non-small-cell lung cancer
-
A. Singh, V. Misra, R.K. Thimmulappa, H. Lee, S. Ames, M.O. Hoque, J.G. Herman, S.B. Baylin, D. Sidransky, E. Gabrielson, M.V. Brock, and S. Biswal Dysfunctional Keap1-Nrf2 interaction in non-small-cell lung cancer PLoS Med 3 2006 e420
-
(2006)
PLoS Med
, vol.3
, pp. e420
-
-
Singh, A.1
Misra, V.2
Thimmulappa, R.K.3
Lee, H.4
Ames, S.5
Hoque, M.O.6
Herman, J.G.7
Baylin, S.B.8
Sidransky, D.9
Gabrielson, E.10
Brock, M.V.11
Biswal, S.12
-
57
-
-
40449107193
-
Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth
-
T. Ohta, K. Iijima, M. Miyamoto, I. Nakahara, H. Tanaka, M. Ohtsuji, T. Suzuki, A. Kobayashi, J. Yokota, T. Sakiyama, T. Shibata, M. Yamamoto, and S. Hirohashi Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth Cancer research 68 2008 1303 1309
-
(2008)
Cancer Research
, vol.68
, pp. 1303-1309
-
-
Ohta, T.1
Iijima, K.2
Miyamoto, M.3
Nakahara, I.4
Tanaka, H.5
Ohtsuji, M.6
Suzuki, T.7
Kobayashi, A.8
Yokota, J.9
Sakiyama, T.10
Shibata, T.11
Yamamoto, M.12
Hirohashi, S.13
-
58
-
-
56649083534
-
Dual roles of Nrf2 in cancer
-
A. Lau, N.F. Villeneuve, Z. Sun, P.K. Wong, and D.D. Zhang Dual roles of Nrf2 in cancer Pharmacol Res 58 2008 262 270
-
(2008)
Pharmacol Res
, vol.58
, pp. 262-270
-
-
Lau, A.1
Villeneuve, N.F.2
Sun, Z.3
Wong, P.K.4
Zhang, D.D.5
-
59
-
-
79952122321
-
Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism
-
D. Ren, N.F. Villeneuve, T. Jiang, T. Wu, A. Lau, H.A. Toppin, and D.D. Zhang Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism Proc Natl Acad Sci U S A 108 2011 1433 1438
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 1433-1438
-
-
Ren, D.1
Villeneuve, N.F.2
Jiang, T.3
Wu, T.4
Lau, A.5
Toppin, H.A.6
Zhang, D.D.7
-
60
-
-
84918576027
-
Oncogenic KRAS confers chemoresistance by upregulating Nrf2
-
S. Tao, S. Wang, S.J. Moghaddam, A. Ooi, E. Chapman, P.K. Wong, and D.D. Zhang Oncogenic KRAS confers chemoresistance by upregulating Nrf2 Cancer research 74 2014 7430 7441
-
(2014)
Cancer Research
, vol.74
, pp. 7430-7441
-
-
Tao, S.1
Wang, S.2
Moghaddam, S.J.3
Ooi, A.4
Chapman, E.5
Wong, P.K.6
Zhang, D.D.7
-
61
-
-
79955492012
-
Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells
-
Y. Inami, S. Waguri, A. Sakamoto, T. Kouno, K. Nakada, O. Hino, S. Watanabe, J. Ando, M. Iwadate, M. Yamamoto, M.S. Lee, K. Tanaka, and M. Komatsu Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells J Cell Biol 193 2011 275 284
-
(2011)
J Cell Biol
, vol.193
, pp. 275-284
-
-
Inami, Y.1
Waguri, S.2
Sakamoto, A.3
Kouno, T.4
Nakada, K.5
Hino, O.6
Watanabe, S.7
Ando, J.8
Iwadate, M.9
Yamamoto, M.10
Lee, M.S.11
Tanaka, K.12
Komatsu, M.13
-
62
-
-
84861466718
-
Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury
-
H.M. Ni, N. Boggess, M.R. McGill, M. Lebofsky, P. Borude, U. Apte, H. Jaeschke, and W.X. Ding Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury Toxicol Sci 127 2012 438 450
-
(2012)
Toxicol Sci
, vol.127
, pp. 438-450
-
-
Ni, H.M.1
Boggess, N.2
McGill, M.R.3
Lebofsky, M.4
Borude, P.5
Apte, U.6
Jaeschke, H.7
Ding, W.X.8
-
63
-
-
84906315540
-
Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy
-
H.M. Ni, B.L. Woolbright, J. Williams, B. Copple, W. Cui, J.P. Luyendyk, H. Jaeschke, and W.X. Ding Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy J Hepatol 61 2014 617 625
-
(2014)
J Hepatol
, vol.61
, pp. 617-625
-
-
Ni, H.M.1
Woolbright, B.L.2
Williams, J.3
Copple, B.4
Cui, W.5
Luyendyk, J.P.6
Jaeschke, H.7
Ding, W.X.8
-
64
-
-
84890025789
-
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction
-
H.C. Lam, S.M. Cloonan, A.R. Bhashyam, J.A. Haspel, A. Singh, J.F. Sathirapongsasuti, M. Cervo, H. Yao, A.L. Chung, K. Mizumura, C.H. An, B. Shan, J.M. Franks, K.J. Haley, C.A. Owen, Y. Tesfaigzi, G.R. Washko, J. Quackenbush, E.K. Silverman, I. Rahman, H.P. Kim, A. Mahmood, S.S. Biswal, S.W. Ryter, and A.M. Choi Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction The Journal of clinical investigation 123 2013 5212 5230
-
(2013)
The Journal of Clinical Investigation
, vol.123
, pp. 5212-5230
-
-
Lam, H.C.1
Cloonan, S.M.2
Bhashyam, A.R.3
Haspel, J.A.4
Singh, A.5
Sathirapongsasuti, J.F.6
Cervo, M.7
Yao, H.8
Chung, A.L.9
Mizumura, K.10
An, C.H.11
Shan, B.12
Franks, J.M.13
Haley, K.J.14
Owen, C.A.15
Tesfaigzi, Y.16
Washko, G.R.17
Quackenbush, J.18
Silverman, E.K.19
Rahman, I.20
Kim, H.P.21
Mahmood, A.22
Biswal, S.S.23
Ryter, S.W.24
Choi, A.M.25
more..
-
65
-
-
79956095420
-
Autophagosome formation and molecular mechanism of autophagy
-
I. Tanida Autophagosome formation and molecular mechanism of autophagy Antioxid Redox Signal 14 2011 2201 2214
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 2201-2214
-
-
Tanida, I.1
-
66
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
-
M. Komatsu, S. Waguri, T. Ueno, J. Iwata, S. Murata, I. Tanida, J. Ezaki, N. Mizushima, Y. Ohsumi, Y. Uchiyama, E. Kominami, K. Tanaka, and T. Chiba Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice J Cell Biol 169 2005 425 434
-
(2005)
J Cell Biol
, vol.169
, pp. 425-434
-
-
Komatsu, M.1
Waguri, S.2
Ueno, T.3
Iwata, J.4
Murata, S.5
Tanida, I.6
Ezaki, J.7
Mizushima, N.8
Ohsumi, Y.9
Uchiyama, Y.10
Kominami, E.11
Tanaka, K.12
Chiba, T.13
-
67
-
-
39749148228
-
Comprehensive proteomics analysis of autophagy-deficient mouse liver
-
N. Matsumoto, J. Ezaki, M. Komatsu, K. Takahashi, R. Mineki, H. Taka, M. Kikkawa, T. Fujimura, M. Takeda-Ezaki, T. Ueno, K. Tanaka, and E. Kominami Comprehensive proteomics analysis of autophagy-deficient mouse liver Biochem Biophys Res Commun 368 2008 643 649
-
(2008)
Biochem Biophys Res Commun
, vol.368
, pp. 643-649
-
-
Matsumoto, N.1
Ezaki, J.2
Komatsu, M.3
Takahashi, K.4
Mineki, R.5
Taka, H.6
Kikkawa, M.7
Fujimura, T.8
Takeda-Ezaki, M.9
Ueno, T.10
Tanaka, K.11
Kominami, E.12
-
68
-
-
78049495046
-
Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: A potential role for protein aggregation in autophagic substrate selection
-
B.E. Riley, S.E. Kaiser, T.A. Shaler, A.C. Ng, T. Hara, M.S. Hipp, K. Lage, R.J. Xavier, K.Y. Ryu, K. Taguchi, M. Yamamoto, K. Tanaka, N. Mizushima, M. Komatsu, and R.R. Kopito Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection J Cell Biol 191 2010 537 552
-
(2010)
J Cell Biol
, vol.191
, pp. 537-552
-
-
Riley, B.E.1
Kaiser, S.E.2
Shaler, T.A.3
Ng, A.C.4
Hara, T.5
Hipp, M.S.6
Lage, K.7
Xavier, R.J.8
Ryu, K.Y.9
Taguchi, K.10
Yamamoto, M.11
Tanaka, K.12
Mizushima, N.13
Komatsu, M.14
Kopito, R.R.15
-
69
-
-
84878544117
-
Autophagy is induced by UVA and promotes removal of oxidized phospholipids and protein aggregates in epidermal keratinocytes
-
Y. Zhao, C.F. Zhang, H. Rossiter, L. Eckhart, U. Konig, S. Karner, M. Mildner, V.N. Bochkov, E. Tschachler, and F. Gruber Autophagy is induced by UVA and promotes removal of oxidized phospholipids and protein aggregates in epidermal keratinocytes J Invest Dermatol 133 2013 1629 1637
-
(2013)
J Invest Dermatol
, vol.133
, pp. 1629-1637
-
-
Zhao, Y.1
Zhang, C.F.2
Rossiter, H.3
Eckhart, L.4
Konig, U.5
Karner, S.6
Mildner, M.7
Bochkov, V.N.8
Tschachler, E.9
Gruber, F.10
-
70
-
-
79551468720
-
Inducible disruption of autophagy in the lung causes airway hyper-responsiveness
-
D. Inoue, H. Kubo, K. Taguchi, T. Suzuki, M. Komatsu, H. Motohashi, and M. Yamamoto Inducible disruption of autophagy in the lung causes airway hyper-responsiveness Biochem Biophys Res Commun 405 2011 13 18
-
(2011)
Biochem Biophys Res Commun
, vol.405
, pp. 13-18
-
-
Inoue, D.1
Kubo, H.2
Taguchi, K.3
Suzuki, T.4
Komatsu, M.5
Motohashi, H.6
Yamamoto, M.7
-
71
-
-
84939535105
-
Suppression of Autophagy Dysregulates the Antioxidant Response and Causes Premature Senescence of Melanocytes
-
C.F. Zhang, F. Gruber, C. Ni, M. Mildner, U. Koenig, S. Karner, C. Barresi, H. Rossiter, M.S. Narzt, I.M. Nagelreiter, L. Larue, D.J. Tobin, L. Eckhart, and E. Tschachler Suppression of Autophagy Dysregulates the Antioxidant Response and Causes Premature Senescence of Melanocytes J Invest Dermatol 2014
-
(2014)
J Invest Dermatol
-
-
Zhang, C.F.1
Gruber, F.2
Ni, C.3
Mildner, M.4
Koenig, U.5
Karner, S.6
Barresi, C.7
Rossiter, H.8
Narzt, M.S.9
Nagelreiter, I.M.10
Larue, L.11
Tobin, D.J.12
Eckhart, L.13
Tschachler, E.14
-
72
-
-
84921671279
-
Kaposi's Sarcoma-Associated Herpesvirus Induces Nrf2 Activation in Latently Infected Endothelial Cells through SQSTM1 Phosphorylation and Interaction with Polyubiquitinated Keap1
-
O. Gjyshi, S. Flaherty, M.V. Veettil, K.E. Johnson, B. Chandran, and V. Bottero Kaposi's Sarcoma-Associated Herpesvirus Induces Nrf2 Activation in Latently Infected Endothelial Cells through SQSTM1 Phosphorylation and Interaction with Polyubiquitinated Keap1 J Virol 89 2015 2268 2286
-
(2015)
J Virol
, vol.89
, pp. 2268-2286
-
-
Gjyshi, O.1
Flaherty, S.2
Veettil, M.V.3
Johnson, K.E.4
Chandran, B.5
Bottero, V.6
-
73
-
-
84894428173
-
Autophagy promotes BrafV600E-driven lung tumorigenesis by preserving mitochondrial metabolism
-
A.M. Strohecker, and E. White Autophagy promotes BrafV600E-driven lung tumorigenesis by preserving mitochondrial metabolism Autophagy 10 2014 384 385
-
(2014)
Autophagy
, vol.10
, pp. 384-385
-
-
Strohecker, A.M.1
White, E.2
-
74
-
-
84885350394
-
Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors
-
A.M. Strohecker, J.Y. Guo, G. Karsli-Uzunbas, S.M. Price, G.J. Chen, R. Mathew, M. McMahon, and E. White Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors Cancer discovery 3 2013 1272 1285
-
(2013)
Cancer Discovery
, vol.3
, pp. 1272-1285
-
-
Strohecker, A.M.1
Guo, J.Y.2
Karsli-Uzunbas, G.3
Price, S.M.4
Chen, G.J.5
Mathew, R.6
McMahon, M.7
White, E.8
-
75
-
-
84885944468
-
The emerging role of the Nrf2-Keap1 signaling pathway in cancer
-
M.C. Jaramillo, and D.D. Zhang The emerging role of the Nrf2-Keap1 signaling pathway in cancer Genes Dev 27 2013 2179 2191
-
(2013)
Genes Dev
, vol.27
, pp. 2179-2191
-
-
Jaramillo, M.C.1
Zhang, D.D.2
|