Changed conformation of mutant tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of tau-4R/2N transgenic mice

Journal of Biological Chemistry

Volumn 280, Issue 5, 2005, Pages 3963-3973

  Terwel, Dick ^a   Lasrado, Reena ^a   Snauwaert, Johan ^a   Vandeweert, Erno ^a   Van Haesendonck, Chris ^a   Borghgraef, Peter ^a   Van Leuven, Fred ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CONFORMATIONS; GENES; PATHOLOGY;

CONFORMATIONAL CHANGES; NEURODEGENERATION; PHOSPHORYLATION;

MUTAGENESIS;

MICROTUBULE ASSOCIATED PROTEIN; MUTANT PROTEIN; PROTEIN P30; PROTEIN TAU 2N; PROTEIN TAU 4R; THY 1 ANTIGEN; UNCLASSIFIED DRUG;

AGING; ANIMAL TISSUE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DYING; EMBRYO; HUMAN; MOTOR DYSFUNCTION; MOUSE; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NEUROPATHY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; TAUOPATHY; TRANSGENIC MOUSE;

AGING; ANIMALS; AXONS; CENTRAL NERVOUS SYSTEM; EPITOPES; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MOTOR ACTIVITY; MOTOR NEURONS; PHOSPHORYLATION; PROTEIN CONFORMATION; TAU PROTEINS; TAUOPATHIES;

ANIMALIA; MUS MUSCULUS;

EID: 13644268449     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M409876200     Document Type: Article

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