Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway

Molecular Neurodegeneration

Volumn 7, Issue 1, 2012, Pages

  Inoue, Keiichi ^a   Rispoli, Joanne ^a   Kaphzan, Hanoch ^b   Klann, Eric ^b   Chen, Emily I ^c   Kim, Jongpil ^a   Komatsu, Masaaki ^d   Abeliovich, Asa ^a  

^a NewYork Presbyterian Hospital   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c STONY BROOK UNIVERSITY   (United States)

^d TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 7; GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN; TAU PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE DELETION; MACROAUTOPHAGY; MACROAUTOPHAGY DEFICIENCY; MALE; MOUSE; NERVE CELL; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NONHUMAN; PROTEIN DEFECT; PROTEIN PHOSPHORYLATION; TAUOPATHY;

AGING; ANIMALS; AUTOPHAGY; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; MICROTUBULE-ASSOCIATED PROTEINS; NERVE DEGENERATION; NEURONS; PHOSPHORYLATION; PROSENCEPHALON; SIGNAL TRANSDUCTION; TAU PROTEINS;

MUS;

EID: 84866519178     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/1750-1326-7-48     Document Type: Article

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