Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model

Journal of Neuroscience

Volumn 32, Issue 49, 2012, Pages 17775-17787

  Gan, Li ^a   Vargas, Marcelo R ^a,c   Johnson, Delinda A ^a   Johnson, Jeffrey A ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; CHAPERONE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTATHIONE; PROTEIN P47; PROTEIN P67; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SYNUCLEIN; TRANSCRIPTION FACTOR NRF2;

ANIMAL TISSUE; ARTICLE; ASTROCYTE; AUTOPHAGY; CELL SURVIVAL; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; GENE EXPRESSION; GLIOSIS; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MACROAUTOPHAGY; MALE; MOTONEURON; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; WESTERN BLOTTING;

ALPHA-SYNUCLEIN; ANIMALS; ANTIOXIDANT RESPONSE ELEMENTS; ASTROCYTES; AUTOPHAGY; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; FEMALE; GLIOSIS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR NEURONS; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PARKINSON DISEASE; PHOSPHORYLATION;

EID: 84870549095     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3049-12.2012     Document Type: Article

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