Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells

eLife

Volumn 5, Issue 2016JULY, 2016, Pages

  Allison, Karmel A ^a,b   Sajti, Eniko ^c,d   Collier, Jana G ^a   Gosselin, David ^a   Troutman, Ty Dale ^a   Stone, Erica L ^b,e   Hedrick, Stephen M ^a,b   Glass, Christopher K ^a,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d RADY CHILDREN'S HOSPITAL   (United States)

^e WISTAR INSTITUTE   (United States)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD200 ANTIGEN; CD69 ANTIGEN; GLYCOPROTEIN P 15095; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 2 RECEPTOR ALPHA; LYMPHOCYTE ANTIGEN; NUCLEAR RECEPTOR NUR77; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR T BET; ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL INTERACTION; CONTROLLED STUDY; FLOW CYTOMETRY; GENE ACTIVITY; GENE EXPRESSION; GENE SEQUENCE; MOUSE; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; SIGNAL TRANSDUCTION; ANIMAL; DRUG EFFECTS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM;

ANIMALS; ANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; GENE EXPRESSION; LYMPHOCYTE ACTIVATION; MICE; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION;

EID: 84979641056     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.10134     Document Type: Article

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