메뉴 건너뛰기




Volumn 37, Issue 6, 2012, Pages 1130-1144

Network Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8+ T Cell Exhaustion versus Memory

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; DNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EOMES; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG;

EID: 84870922385     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2012.08.021     Document Type: Article
Times cited : (406)

References (53)
  • 1
    • 77956963618 scopus 로고    scopus 로고
    • Shared dependence on the DNA-binding factor TOX for the development of lymphoid tissue-inducer cell and NK cell lineages
    • Aliahmad P., de la Torre B., Kaye J. Shared dependence on the DNA-binding factor TOX for the development of lymphoid tissue-inducer cell and NK cell lineages. Nat. Immunol. 2010, 11:945-952.
    • (2010) Nat. Immunol. , vol.11 , pp. 945-952
    • Aliahmad, P.1    de la Torre, B.2    Kaye, J.3
  • 2
    • 84864378851 scopus 로고    scopus 로고
    • Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection
    • Angelosanto J.M., Blackburn S.D., Crawford A., Wherry E.J. Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection. J. Virol. 2012, 86:8161-8170.
    • (2012) J. Virol. , vol.86 , pp. 8161-8170
    • Angelosanto, J.M.1    Blackburn, S.D.2    Crawford, A.3    Wherry, E.J.4
  • 6
    • 54449088740 scopus 로고    scopus 로고
    • Selective expansion of a subset of exhausted CD8 T cells by anti-PD-L1 blockade
    • Blackburn S.D., Shin H., Freeman G.J., Wherry E.J. Selective expansion of a subset of exhausted CD8 T cells by anti-PD-L1 blockade. Proc Natl Acad Sci USA 2008, 105:15016-15021.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15016-15021
    • Blackburn, S.D.1    Shin, H.2    Freeman, G.J.3    Wherry, E.J.4
  • 8
    • 33745205112 scopus 로고    scopus 로고
    • Reprogramming of antiviral T cells prevents inactivation and restores T cell activity during persistent viral infection
    • Brooks D.G., McGavern D.B., Oldstone M.B. Reprogramming of antiviral T cells prevents inactivation and restores T cell activity during persistent viral infection. J. Clin. Invest. 2006, 116:1675-1685.
    • (2006) J. Clin. Invest. , vol.116 , pp. 1675-1685
    • Brooks, D.G.1    McGavern, D.B.2    Oldstone, M.B.3
  • 9
    • 84984932472 scopus 로고    scopus 로고
    • Exploring the new world of the genome with DNA microarrays
    • Brown P.O., Botstein D. Exploring the new world of the genome with DNA microarrays. Nat. Genet. 1999, 21(1, Suppl):33-37.
    • (1999) Nat. Genet. , vol.21 , Issue.1 SUPPL , pp. 33-37
    • Brown, P.O.1    Botstein, D.2
  • 10
    • 33645221650 scopus 로고    scopus 로고
    • Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks
    • Carlson M.R., Zhang B., Fang Z., Mischel P.S., Horvath S., Nelson S.F. Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks. BMC Genomics 2006, 7:40.
    • (2006) BMC Genomics , vol.7 , pp. 40
    • Carlson, M.R.1    Zhang, B.2    Fang, Z.3    Mischel, P.S.4    Horvath, S.5    Nelson, S.F.6
  • 11
    • 5044245707 scopus 로고    scopus 로고
    • Gene co-expression network topology provides a framework for molecular characterization of cellular state
    • Carter S.L., Brechbühler C.M., Griffin M., Bond A.T. Gene co-expression network topology provides a framework for molecular characterization of cellular state. Bioinformatics 2004, 20:2242-2250.
    • (2004) Bioinformatics , vol.20 , pp. 2242-2250
    • Carter, S.L.1    Brechbühler, C.M.2    Griffin, M.3    Bond, A.T.4
  • 13
    • 34447512704 scopus 로고    scopus 로고
    • Understanding network concepts in modules
    • Dong J., Horvath S. Understanding network concepts in modules. BMC Syst. Biol. 2007, 1:24.
    • (2007) BMC Syst. Biol. , vol.1 , pp. 24
    • Dong, J.1    Horvath, S.2
  • 14
    • 60849139395 scopus 로고    scopus 로고
    • GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
    • Eden E., Navon R., Steinfeld I., Lipson D., Yakhini Z. GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists. BMC Bioinformatics 2009, 10:48.
    • (2009) BMC Bioinformatics , vol.10 , pp. 48
    • Eden, E.1    Navon, R.2    Steinfeld, I.3    Lipson, D.4    Yakhini, Z.5
  • 15
    • 34548550573 scopus 로고    scopus 로고
    • Systematic construction of gene coexpression networks with applications to human T helper cell differentiation process
    • Elo L.L., Järvenpää H., Oresic M., Lahesmaa R., Aittokallio T. Systematic construction of gene coexpression networks with applications to human T helper cell differentiation process. Bioinformatics 2007, 23:2096-2103.
    • (2007) Bioinformatics , vol.23 , pp. 2096-2103
    • Elo, L.L.1    Järvenpää, H.2    Oresic, M.3    Lahesmaa, R.4    Aittokallio, T.5
  • 16
    • 79956069829 scopus 로고    scopus 로고
    • Transcription factor Foxp1 exerts essential cell-intrinsic regulation of the quiescence of naive T cells
    • Feng X., Wang H., Takata H., Day T.J., Willen J., Hu H. Transcription factor Foxp1 exerts essential cell-intrinsic regulation of the quiescence of naive T cells. Nat. Immunol. 2011, 12:544-550.
    • (2011) Nat. Immunol. , vol.12 , pp. 544-550
    • Feng, X.1    Wang, H.2    Takata, H.3    Day, T.J.4    Willen, J.5    Hu, H.6
  • 17
    • 0037221289 scopus 로고    scopus 로고
    • Ablation of CD8 and CD4 T cell responses by high viral loads
    • Fuller M.J., Zajac A.J. Ablation of CD8 and CD4 T cell responses by high viral loads. J. Immunol. 2003, 170:477-486.
    • (2003) J. Immunol. , vol.170 , pp. 477-486
    • Fuller, M.J.1    Zajac, A.J.2
  • 22
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang W., Sherman B.T., Lempicki R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 2009, 4:44-57.
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 25
    • 0037074012 scopus 로고    scopus 로고
    • Molecular and functional profiling of memory CD8 T cell differentiation
    • Kaech S.M., Hemby S., Kersh E., Ahmed R. Molecular and functional profiling of memory CD8 T cell differentiation. Cell 2002, 111:837-851.
    • (2002) Cell , vol.111 , pp. 837-851
    • Kaech, S.M.1    Hemby, S.2    Kersh, E.3    Ahmed, R.4
  • 27
    • 0030823769 scopus 로고    scopus 로고
    • LKLF: A transcriptional regulator of single-positive T cell quiescence and survival
    • Kuo C.T., Veselits M.L., Leiden J.M. LKLF: A transcriptional regulator of single-positive T cell quiescence and survival. Science 1997, 277:1986-1990.
    • (1997) Science , vol.277 , pp. 1986-1990
    • Kuo, C.T.1    Veselits, M.L.2    Leiden, J.M.3
  • 28
    • 41449085571 scopus 로고    scopus 로고
    • Eigengene networks for studying the relationships between co-expression modules
    • Langfelder P., Horvath S. Eigengene networks for studying the relationships between co-expression modules. BMC Syst. Biol. 2007, 1:54.
    • (2007) BMC Syst. Biol. , vol.1 , pp. 54
    • Langfelder, P.1    Horvath, S.2
  • 29
    • 60549111634 scopus 로고    scopus 로고
    • WGCNA: an R package for weighted correlation network analysis
    • Langfelder P., Horvath S. WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics 2008, 9:559.
    • (2008) BMC Bioinformatics , vol.9 , pp. 559
    • Langfelder, P.1    Horvath, S.2
  • 32
    • 4644326931 scopus 로고    scopus 로고
    • Genomic analysis of regulatory network dynamics reveals large topological changes
    • Luscombe N.M., Babu M.M., Yu H., Snyder M., Teichmann S.A., Gerstein M. Genomic analysis of regulatory network dynamics reveals large topological changes. Nature 2004, 431:308-312.
    • (2004) Nature , vol.431 , pp. 308-312
    • Luscombe, N.M.1    Babu, M.M.2    Yu, H.3    Snyder, M.4    Teichmann, S.A.5    Gerstein, M.6
  • 35
    • 64049102658 scopus 로고    scopus 로고
    • Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells
    • Ng S.Y., Yoshida T., Zhang J., Georgopoulos K. Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells. Immunity 2009, 30:493-507.
    • (2009) Immunity , vol.30 , pp. 493-507
    • Ng, S.Y.1    Yoshida, T.2    Zhang, J.3    Georgopoulos, K.4
  • 41
    • 74249118093 scopus 로고    scopus 로고
    • Aging mice show a decreasing correlation of gene expression within genetic modules
    • Southworth L.K., Owen A.B., Kim S.K. Aging mice show a decreasing correlation of gene expression within genetic modules. PLoS Genet. 2009, 5:e1000776.
    • (2009) PLoS Genet. , vol.5
    • Southworth, L.K.1    Owen, A.B.2    Kim, S.K.3
  • 46
    • 79956077563 scopus 로고    scopus 로고
    • T cell exhaustion
    • Wherry E.J. T cell exhaustion. Nat. Immunol. 2011, 12:492-499.
    • (2011) Nat. Immunol. , vol.12 , pp. 492-499
    • Wherry, E.J.1
  • 47
    • 0037383592 scopus 로고    scopus 로고
    • Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
    • Wherry E.J., Blattman J.N., Murali-Krishna K., van der Most R., Ahmed R. Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J. Virol. 2003, 77:4911-4927.
    • (2003) J. Virol. , vol.77 , pp. 4911-4927
    • Wherry, E.J.1    Blattman, J.N.2    Murali-Krishna, K.3    van der Most, R.4    Ahmed, R.5
  • 49
    • 34247849183 scopus 로고    scopus 로고
    • Effector and memory CTL differentiation
    • Williams M.A., Bevan M.J. Effector and memory CTL differentiation. Annu. Rev. Immunol. 2007, 25:171-192.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 171-192
    • Williams, M.A.1    Bevan, M.J.2
  • 51
    • 33847129641 scopus 로고    scopus 로고
    • Gene network interconnectedness and the generalized topological overlap measure
    • Yip A.M., Horvath S. Gene network interconnectedness and the generalized topological overlap measure. BMC Bioinformatics 2007, 8:22.
    • (2007) BMC Bioinformatics , vol.8 , pp. 22
    • Yip, A.M.1    Horvath, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.