MEK inhibition, alone or in combination with BRAF inhibition, affects multiple functions of isolated normal human lymphocytes and dendritic cells

Cancer immunology research

Volumn 2, Issue 4, 2014, Pages 351-360

  Vella, Laura J ^a   Pasam, Anupama ^a   Dimopoulos, Nektaria ^a   Andrews, Miles ^a   Knights, Ashley ^a   Puaux, Anne Laure ^a   Louahed, Jamila ^a   Chen, Weisan ^a   Woods, Katherine ^a   Cebon, Jonathan S ^a  

^a GSK   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; CYTOKINE; DABRAFENIB; EPITOPE; IMIDAZOLE DERIVATIVE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; OXIME; PROTEIN KINASE INHIBITOR; PYRIDONE DERIVATIVE; PYRIMIDINONE DERIVATIVE; TRAMETINIB; TUMOR ANTIGEN;

ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CROSS PRESENTATION; CYTOLOGY; DENDRITIC CELL; DRUG EFFECTS; HUMAN; IMMUNOLOGY; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBPOPULATION; METABOLISM;

ANTIGENS, NEOPLASM; CELL DIFFERENTIATION; CELL PROLIFERATION; CROSS-PRIMING; CYTOKINES; DENDRITIC CELLS; EPITOPES, T-LYMPHOCYTE; HUMANS; IMIDAZOLES; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; LYMPHOCYTES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; OXIMES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS B-RAF; PYRIDONES; PYRIMIDINONES;

EID: 84904286464     PISSN: None     EISSN: 23266074     Source Type: Journal    
DOI: 10.1158/2326-6066.CIR-13-0181     Document Type: Article

References (0)