Origin of the sharp boundary that discriminates positive and negative selection of thymocytes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 2, 2009, Pages 528-533

  Prasad, Ashok ^a   Zikherman, Julie ^c   Das, Jayajit ^a   Roose, Jeroen P ^c   Weiss, Arthur ^c,d   Chakraborty, Arup K ^a,b  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Positive feedback; Ras activation; Signal transduction; T cell antigen receptor; Thymic development

Indexed keywords

RAS PROTEIN;

ARTICLE; BINDING AFFINITY; CELL MIGRATION; COMPUTER SIMULATION; ENZYME ACTIVATION; GENETIC SELECTION; LIGAND BINDING; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE; THYMOCYTE;

ANIMALS; AUTOIMMUNITY; COMPUTER SIMULATION; HISTOCOMPATIBILITY ANTIGENS; LIGANDS; MICE; PEPTIDES; RAS PROTEINS; RECEPTORS, ANTIGEN, T-CELL; SELF TOLERANCE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; THYMUS GLAND;

EID: 58249087468     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0805981105     Document Type: Article

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