Effect of natural genetic variation on enhancer selection and function

Nature

Volumn 503, Issue 7477, 2013, Pages 487-492

  Heinz, S ^a   Romanoski, C E ^a   Benner, C ^a,b,c   Allison, K A ^a   Kaikkonen, M U ^a,d   Orozco, L D ^e   Glass, C K ^a,c,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c University of California San Diego   (United States)

^d UNIVERSITY OF EASTERN FINLAND   (Finland)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

CHEMICAL BINDING; GENETIC VARIATION; GENOME; HIERARCHICAL SYSTEM; MUTAGENICITY; PHENOTYPE; PRIORITIZATION; RODENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENHANCER REGION; EPIGENETICS; GENETIC VARIABILITY; GENOME; HISTONE MODIFICATION; MACROPHAGE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

AMINO ACID MOTIFS; ANIMALS; BASE SEQUENCE; CELL LINEAGE; DNA-BINDING PROTEINS; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION; GENETIC VARIATION; HISTONES; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MODELS, BIOLOGICAL; MUTATION; NF-KAPPA B; PROTEIN BINDING; REPRODUCIBILITY OF RESULTS; SELECTION, GENETIC; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTORS;

EID: 84888641656     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12615     Document Type: Article

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