메뉴 건너뛰기




Volumn 49, Issue 2, 2013, Pages 249-261

Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE;

EID: 84872796463     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2012.11.002     Document Type: Article
Times cited : (376)

References (57)
  • 1
    • 27844541328 scopus 로고    scopus 로고
    • Modeling T cell antigen discrimination based on feedback control of digital ERK responses
    • Altan-Bonnet G., Germain R.N. Modeling T cell antigen discrimination based on feedback control of digital ERK responses. PLoS Biol. 2005, 3:e356.
    • (2005) PLoS Biol. , vol.3
    • Altan-Bonnet, G.1    Germain, R.N.2
  • 3
    • 0034496282 scopus 로고    scopus 로고
    • The role of transient ERK2 signals in fibronectin- and insulin-mediated DNA synthesis
    • Asthagiri A.R., Reinhart C.A., Horwitz A.F., Lauffenburger D.A. The role of transient ERK2 signals in fibronectin- and insulin-mediated DNA synthesis. J. Cell Sci. 2000, 113:4499-4510.
    • (2000) J. Cell Sci. , vol.113 , pp. 4499-4510
    • Asthagiri, A.R.1    Reinhart, C.A.2    Horwitz, A.F.3    Lauffenburger, D.A.4
  • 5
    • 33644856401 scopus 로고    scopus 로고
    • Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase
    • Balan V., Leicht D.T., Zhu J., Balan K., Kaplun A., Singh-Gupta V., Qin J., Ruan H., Comb M.J., Tzivion G. Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase. Mol. Biol. Cell 2006, 17:1141-1153.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 1141-1153
    • Balan, V.1    Leicht, D.T.2    Zhu, J.3    Balan, K.4    Kaplun, A.5    Singh-Gupta, V.6    Qin, J.7    Ruan, H.8    Comb, M.J.9    Tzivion, G.10
  • 6
    • 81155137325 scopus 로고    scopus 로고
    • Linear approaches to intramolecular Förster resonance energy transfer probe measurements for quantitative modeling
    • Birtwistle M.R., von Kriegsheim A., Kida K., Schwarz J.P., Anderson K.I., Kolch W. Linear approaches to intramolecular Förster resonance energy transfer probe measurements for quantitative modeling. PLoS ONE 2011, 6:e27823.
    • (2011) PLoS ONE , vol.6
    • Birtwistle, M.R.1    von Kriegsheim, A.2    Kida, K.3    Schwarz, J.P.4    Anderson, K.I.5    Kolch, W.6
  • 9
    • 71149086211 scopus 로고    scopus 로고
    • Cell signaling: what is the signal and what information does it carry?
    • Brent R. Cell signaling: what is the signal and what information does it carry?. FEBS Lett. 2009, 583:4019-4024.
    • (2009) FEBS Lett. , vol.583 , pp. 4019-4024
    • Brent, R.1
  • 10
    • 0031033716 scopus 로고    scopus 로고
    • The dual specificity mitogen-activated protein kinase phosphatase-1 and -2 are induced by the p42/p44MAPK cascade
    • Brondello J.M., Brunet A., Pouysségur J., McKenzie F.R. The dual specificity mitogen-activated protein kinase phosphatase-1 and -2 are induced by the p42/p44MAPK cascade. J. Biol. Chem. 1997, 272:1368-1376.
    • (1997) J. Biol. Chem. , vol.272 , pp. 1368-1376
    • Brondello, J.M.1    Brunet, A.2    Pouysségur, J.3    McKenzie, F.R.4
  • 11
    • 0038832564 scopus 로고    scopus 로고
    • Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation
    • Brondello J.M., Pouysségur J., McKenzie F.R. Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation. Science 1999, 286:2514-2517.
    • (1999) Science , vol.286 , pp. 2514-2517
    • Brondello, J.M.1    Pouysségur, J.2    McKenzie, F.R.3
  • 12
    • 0347363834 scopus 로고    scopus 로고
    • Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf
    • Brummer T., Naegele H., Reth M., Misawa Y. Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf. Oncogene 2003, 22:8823-8834.
    • (2003) Oncogene , vol.22 , pp. 8823-8834
    • Brummer, T.1    Naegele, H.2    Reth, M.3    Misawa, Y.4
  • 13
    • 52949098296 scopus 로고    scopus 로고
    • Frequency-modulated nuclear localization bursts coordinate gene regulation
    • Cai L., Dalal C.K., Elowitz M.B. Frequency-modulated nuclear localization bursts coordinate gene regulation. Nature 2008, 455:485-490.
    • (2008) Nature , vol.455 , pp. 485-490
    • Cai, L.1    Dalal, C.K.2    Elowitz, M.B.3
  • 14
    • 0038655412 scopus 로고    scopus 로고
    • Accumulation of Fra-1 in ras-transformed cells depends on both transcriptional autoregulation and MEK-dependent posttranslational stabilization
    • Casalino L., De Cesare D., Verde P. Accumulation of Fra-1 in ras-transformed cells depends on both transcriptional autoregulation and MEK-dependent posttranslational stabilization. Mol. Cell. Biol. 2003, 23:4401-4415.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 4401-4415
    • Casalino, L.1    De Cesare, D.2    Verde, P.3
  • 16
    • 71149092283 scopus 로고    scopus 로고
    • Dynamics and variability of ERK2 response to EGF in individual living cells
    • Cohen-Saidon C., Cohen A.A., Sigal A., Liron Y., Alon U. Dynamics and variability of ERK2 response to EGF in individual living cells. Mol. Cell 2009, 36:885-893.
    • (2009) Mol. Cell , vol.36 , pp. 885-893
    • Cohen-Saidon, C.1    Cohen, A.A.2    Sigal, A.3    Liron, Y.4    Alon, U.5
  • 19
    • 0025831426 scopus 로고
    • Multiple growth factor independence in rat mammary carcinoma cells
    • Ethier S.P., Moorthy R. Multiple growth factor independence in rat mammary carcinoma cells. Breast Cancer Res. Treat. 1991, 18:73-81.
    • (1991) Breast Cancer Res. Treat. , vol.18 , pp. 73-81
    • Ethier, S.P.1    Moorthy, R.2
  • 20
    • 34447099234 scopus 로고    scopus 로고
    • Probing the limits to positional information
    • Gregor T., Tank D.W., Wieschaus E.F., Bialek W. Probing the limits to positional information. Cell 2007, 130:153-164.
    • (2007) Cell , vol.130 , pp. 153-164
    • Gregor, T.1    Tank, D.W.2    Wieschaus, E.F.3    Bialek, W.4
  • 21
    • 84855424553 scopus 로고    scopus 로고
    • Signal-dependent dynamics of transcription factor translocation controls gene expression
    • Hao N., O'Shea E.K. Signal-dependent dynamics of transcription factor translocation controls gene expression. Nat. Struct. Mol. Biol. 2012, 19:31-39.
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 31-39
    • Hao, N.1    O'Shea, E.K.2
  • 24
    • 0035150990 scopus 로고    scopus 로고
    • Growth-factor-dependent mitogenesis requires two distinct phases of signalling
    • Jones S.M., Kazlauskas A. Growth-factor-dependent mitogenesis requires two distinct phases of signalling. Nat. Cell Biol. 2001, 3:165-172.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 165-172
    • Jones, S.M.1    Kazlauskas, A.2
  • 25
    • 0034019315 scopus 로고    scopus 로고
    • Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades
    • Kholodenko B.N. Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades. Eur. J. Biochem. 2000, 267:1583-1588.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 1583-1588
    • Kholodenko, B.N.1
  • 26
    • 67650477014 scopus 로고    scopus 로고
    • Tunable interplay between epidermal growth factor and cell-cell contact governs the spatial dynamics of epithelial growth
    • Kim J.H., Kushiro K., Graham N.A., Asthagiri A.R. Tunable interplay between epidermal growth factor and cell-cell contact governs the spatial dynamics of epithelial growth. Proc. Natl. Acad. Sci. USA 2009, 106:11149-11153.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 11149-11153
    • Kim, J.H.1    Kushiro, K.2    Graham, N.A.3    Asthagiri, A.R.4
  • 28
    • 80052211582 scopus 로고    scopus 로고
    • Rapid phospho-turnover by receptor tyrosine kinases impacts downstream signaling and drug binding
    • Kleiman L.B., Maiwald T., Conzelmann H., Lauffenburger D.A., Sorger P.K. Rapid phospho-turnover by receptor tyrosine kinases impacts downstream signaling and drug binding. Mol. Cell 2011, 43:723-737.
    • (2011) Mol. Cell , vol.43 , pp. 723-737
    • Kleiman, L.B.1    Maiwald, T.2    Conzelmann, H.3    Lauffenburger, D.A.4    Sorger, P.K.5
  • 29
    • 0021333875 scopus 로고
    • Relationship between epidermal growth factor receptor occupancy and mitogenic response. Quantitative analysis using a steady state model system
    • Knauer D.J., Wiley H.S., Cunningham D.D. Relationship between epidermal growth factor receptor occupancy and mitogenic response. Quantitative analysis using a steady state model system. J. Biol. Chem. 1984, 259:5623-5631.
    • (1984) J. Biol. Chem. , vol.259 , pp. 5623-5631
    • Knauer, D.J.1    Wiley, H.S.2    Cunningham, D.D.3
  • 32
    • 33847710201 scopus 로고    scopus 로고
    • CellProfiler: free, versatile software for automated biological image analysis
    • Lamprecht M.R., Sabatini D.M., Carpenter A.E. CellProfiler: free, versatile software for automated biological image analysis. Biotechniques 2007, 42:71-75.
    • (2007) Biotechniques , vol.42 , pp. 71-75
    • Lamprecht, M.R.1    Sabatini, D.M.2    Carpenter, A.E.3
  • 33
    • 0028829346 scopus 로고
    • Negative feedback regulation and desensitization of insulin- and epidermal growth factor-stimulated p21ras activation
    • Langlois W.J., Sasaoka T., Saltiel A.R., Olefsky J.M. Negative feedback regulation and desensitization of insulin- and epidermal growth factor-stimulated p21ras activation. J. Biol. Chem. 1995, 270:25320-25323.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25320-25323
    • Langlois, W.J.1    Sasaoka, T.2    Saltiel, A.R.3    Olefsky, J.M.4
  • 34
    • 11844294679 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases phosphorylate mitogen-activated protein kinase phosphatase 3/DUSP6 at serines 159 and 197, two sites critical for its proteasomal degradation
    • Marchetti S., Gimond C., Chambard J.C., Touboul T., Roux D., Pouysségur J., Pagès G. Extracellular signal-regulated kinases phosphorylate mitogen-activated protein kinase phosphatase 3/DUSP6 at serines 159 and 197, two sites critical for its proteasomal degradation. Mol. Cell. Biol. 2005, 25:854-864.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 854-864
    • Marchetti, S.1    Gimond, C.2    Chambard, J.C.3    Touboul, T.4    Roux, D.5    Pouysségur, J.6    Pagès, G.7
  • 35
  • 36
    • 0842288229 scopus 로고    scopus 로고
    • Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades
    • Markevich N.I., Hoek J.B., Kholodenko B.N. Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades. J. Cell Biol. 2004, 164:353-359.
    • (2004) J. Cell Biol. , vol.164 , pp. 353-359
    • Markevich, N.I.1    Hoek, J.B.2    Kholodenko, B.N.3
  • 37
    • 0036051342 scopus 로고    scopus 로고
    • Molecular interpretation of ERK signal duration by immediate early gene products
    • Murphy L.O., Smith S., Chen R.H., Fingar D.C., Blenis J. Molecular interpretation of ERK signal duration by immediate early gene products. Nat. Cell Biol. 2002, 4:556-564.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 556-564
    • Murphy, L.O.1    Smith, S.2    Chen, R.H.3    Fingar, D.C.4    Blenis, J.5
  • 40
  • 41
    • 0028359984 scopus 로고
    • Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1)
    • Pagès G., Brunet A., L'Allemain G., Pouysségur J. Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1). EMBO J. 1994, 13:3003-3010.
    • (1994) EMBO J. , vol.13 , pp. 3003-3010
    • Pagès, G.1    Brunet, A.2    L'Allemain, G.3    Pouysségur, J.4
  • 42
    • 34848893336 scopus 로고    scopus 로고
    • Bistability and oscillations in the Huang-Ferrell model of MAPK signaling
    • Qiao L., Nachbar R.B., Kevrekidis I.G., Shvartsman S.Y. Bistability and oscillations in the Huang-Ferrell model of MAPK signaling. PLoS Comput. Biol. 2007, 3:1819-1826.
    • (2007) PLoS Comput. Biol. , vol.3 , pp. 1819-1826
    • Qiao, L.1    Nachbar, R.B.2    Kevrekidis, I.G.3    Shvartsman, S.Y.4
  • 44
    • 33847355217 scopus 로고    scopus 로고
    • Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate
    • Santos S.D., Verveer P.J., Bastiaens P.I. Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate. Nat. Cell Biol. 2007, 9:324-330.
    • (2007) Nat. Cell Biol. , vol.9 , pp. 324-330
    • Santos, S.D.1    Verveer, P.J.2    Bastiaens, P.I.3
  • 47
    • 65249103982 scopus 로고    scopus 로고
    • Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway
    • Shin S.Y., Rath O., Choo S.M., Fee F., McFerran B., Kolch W., Cho K.H. Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway. J. Cell Sci. 2009, 122:425-435.
    • (2009) J. Cell Sci. , vol.122 , pp. 425-435
    • Shin, S.Y.1    Rath, O.2    Choo, S.M.3    Fee, F.4    McFerran, B.5    Kolch, W.6    Cho, K.H.7
  • 49
    • 43849094043 scopus 로고    scopus 로고
    • Growth factor contents of autologous human sera prepared by different production methods and their biological effects on chondrocytes
    • Tanaka Y., Ogasawara T., Asawa Y., Yamaoka H., Nishizawa S., Mori Y., Takato T., Hoshi K. Growth factor contents of autologous human sera prepared by different production methods and their biological effects on chondrocytes. Cell Biol. Int. 2008, 32:505-514.
    • (2008) Cell Biol. Int. , vol.32 , pp. 505-514
    • Tanaka, Y.1    Ogasawara, T.2    Asawa, Y.3    Yamaoka, H.4    Nishizawa, S.5    Mori, Y.6    Takato, T.7    Hoshi, K.8
  • 50
    • 77954541844 scopus 로고    scopus 로고
    • Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing
    • Tay S., Hughey J.J., Lee T.K., Lipniacki T., Quake S.R., Covert M.W. Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing. Nature 2010, 466:267-271.
    • (2010) Nature , vol.466 , pp. 267-271
    • Tay, S.1    Hughey, J.J.2    Lee, T.K.3    Lipniacki, T.4    Quake, S.R.5    Covert, M.W.6
  • 51
    • 0028483678 scopus 로고
    • EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor
    • Traverse S., Seedorf K., Paterson H., Marshall C.J., Cohen P., Ullrich A. EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor. Curr. Biol. 1994, 4:694-701.
    • (1994) Curr. Biol. , vol.4 , pp. 694-701
    • Traverse, S.1    Seedorf, K.2    Paterson, H.3    Marshall, C.J.4    Cohen, P.5    Ullrich, A.6
  • 52
    • 0346882607 scopus 로고    scopus 로고
    • Elevated ERK-MAP kinase activity protects the FOS family member FRA-1 against proteasomal degradation in colon carcinoma cells
    • Vial E., Marshall C.J. Elevated ERK-MAP kinase activity protects the FOS family member FRA-1 against proteasomal degradation in colon carcinoma cells. J. Cell Sci. 2003, 116:4957-4963.
    • (2003) J. Cell Sci. , vol.116 , pp. 4957-4963
    • Vial, E.1    Marshall, C.J.2
  • 53
    • 0025139326 scopus 로고
    • Ligand-induced transformation by a noninternalizing epidermal growth factor receptor
    • Wells A., Welsh J.B., Lazar C.S., Wiley H.S., Gill G.N., Rosenfeld M.G. Ligand-induced transformation by a noninternalizing epidermal growth factor receptor. Science 1990, 247:962-964.
    • (1990) Science , vol.247 , pp. 962-964
    • Wells, A.1    Welsh, J.B.2    Lazar, C.S.3    Wiley, H.S.4    Gill, G.N.5    Rosenfeld, M.G.6
  • 54
    • 84857945379 scopus 로고    scopus 로고
    • Akt and ERK control the proliferative response of mammary epithelial cells to the growth factors IGF-1 and EGF through the cell cycle inhibitor p57Kip2
    • Worster D.T., Schmelzle T., Solimini N.L., Lightcap E.S., Millard B., Mills G.B., Brugge J.S., Albeck J.G. Akt and ERK control the proliferative response of mammary epithelial cells to the growth factors IGF-1 and EGF through the cell cycle inhibitor p57Kip2. Sci. Signal. 2012, 5:ra19.
    • (2012) Sci. Signal. , vol.5
    • Worster, D.T.1    Schmelzle, T.2    Solimini, N.L.3    Lightcap, E.S.4    Millard, B.5    Mills, G.B.6    Brugge, J.S.7    Albeck, J.G.8
  • 55
    • 33744974769 scopus 로고    scopus 로고
    • Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression
    • Yamamoto T., Ebisuya M., Ashida F., Okamoto K., Yonehara S., Nishida E. Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression. Curr. Biol. 2006, 16:1171-1182.
    • (2006) Curr. Biol. , vol.16 , pp. 1171-1182
    • Yamamoto, T.1    Ebisuya, M.2    Ashida, F.3    Okamoto, K.4    Yonehara, S.5    Nishida, E.6
  • 56
    • 43149108161 scopus 로고    scopus 로고
    • A bistable Rb-E2F switch underlies the restriction point
    • Yao G., Lee T.J., Mori S., Nevins J.R., You L. A bistable Rb-E2F switch underlies the restriction point. Nat. Cell Biol. 2008, 10:476-482.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 476-482
    • Yao, G.1    Lee, T.J.2    Mori, S.3    Nevins, J.R.4    You, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.