-
1
-
-
59149095154
-
A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis
-
[CrossRef] [PubMed]
-
Venteicher, A. S.; Abreu, E. B.; Meng, Z.; McCann, K. E.; Terns, R. M.; Veenstra, T. D.; Terns, M. P.; Artandi, S. E. A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis. Science 2009, 323, 644-648. [CrossRef] [PubMed].
-
(2009)
Science
, vol.323
, pp. 644-648
-
-
Venteicher, A.S.1
Abreu, E.B.2
Meng, Z.3
McCann, K.E.4
Terns, R.M.5
Veenstra, T.D.6
Terns, M.P.7
Artandi, S.E.8
-
2
-
-
0036712072
-
Human telomerase and its regulation
-
[CrossRef] [PubMed]
-
Cong, Y. S.; Wright, W. E.; Shay, J. W. Human telomerase and its regulation. Microbiol. Mol. Biol. Rev. 2002, 66, 407-425. [CrossRef] [PubMed].
-
(2002)
Microbiol. Mol. Biol. Rev
, vol.66
, pp. 407-425
-
-
Cong, Y.S.1
Wright, W.E.2
Shay, J.W.3
-
3
-
-
0033834247
-
Telomere dynamics in cancer progression and prevention: Fundamental differences in human and mouse telomere biology
-
[CrossRef] [PubMed]
-
Wright, W. E.; Shay, J. W. Telomere dynamics in cancer progression and prevention: Fundamental differences in human and mouse telomere biology. Nat. Med. 2000, 6, 849-851. [CrossRef] [PubMed].
-
(2000)
Nat. Med
, vol.6
, pp. 849-851
-
-
Wright, W.E.1
Shay, J.W.2
-
4
-
-
84957571380
-
Reactivation of telomerase in cancer
-
[CrossRef] [PubMed]
-
Akincilar, S. C.; Unal, B.; Tergaonkar, V. Reactivation of telomerase in cancer. Cell Mol. Life Sci. 2016, 73, 1659-1670. [CrossRef] [PubMed].
-
(2016)
Cell Mol. Life Sci
, vol.73
, pp. 1659-1670
-
-
Akincilar, S.C.1
Unal, B.2
Tergaonkar, V.3
-
5
-
-
80052019968
-
Comparative biology of mammalian telomeres: Hypotheses on ancestral states and the roles of telomeres in longevity determination
-
[CrossRef] [PubMed]
-
Gomes, N. M.; Ryder, O. A.; Houck, M. L.; Charter, S. J.; Walker, W.; Forsyth, N. R.; Austad, S. N.; Venditti, C.; Pagel, M.; Shay, J. W.; et al. Comparative biology of mammalian telomeres: Hypotheses on ancestral states and the roles of telomeres in longevity determination. Aging Cell 2011, 10, 761-768. [CrossRef] [PubMed].
-
(2011)
Aging Cell
, vol.10
, pp. 761-768
-
-
Gomes, N.M.1
Ryder, O.A.2
Houck, M.L.3
Charter, S.J.4
Walker, W.5
Forsyth, N.R.6
Austad, S.N.7
Venditti, C.8
Pagel, M.9
Shay, J.W.10
-
6
-
-
29444435624
-
Differential cis-regulation of human versus mouse TERT gene expression in vivo: Identification of a human-specific repressive element
-
[CrossRef] [PubMed]
-
Horikawa, I.; Chiang, Y. J.; Patterson, T.; Feigenbaum, L.; Leem, S. H.; Michishita, E.; Larionov, V.; Hodes, R. J.; Barrett, J. C. Differential cis-regulation of human versus mouse TERT gene expression in vivo: Identification of a human-specific repressive element. Proc. Natl. Acad. Sci. USA 2005, 102, 18437-18442. [CrossRef] [PubMed].
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 18437-18442
-
-
Horikawa, I.1
Chiang, Y.J.2
Patterson, T.3
Feigenbaum, L.4
Leem, S.H.5
Michishita, E.6
Larionov, V.7
Hodes, R.J.8
Barrett, J.C.9
-
7
-
-
79954571660
-
A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis
-
[CrossRef] [PubMed]
-
Jia, W.; Wang, S.; Horner, J. W.; Wang, N.; Wang, H.; Gunther, E. J.; DePinho, R. A.; Zhu, J. A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis. FASEB J. 2011, 25, 979-989. [CrossRef] [PubMed].
-
(2011)
FASEB J
, vol.25
, pp. 979-989
-
-
Jia, W.1
Wang, S.2
Horner, J.W.3
Wang, N.4
Wang, H.5
Gunther, E.J.6
DePinho, R.A.7
Zhu, J.8
-
8
-
-
0032168370
-
Expression of mouse telomerase catalytic subunit in embryos and adult tissues
-
[CrossRef]
-
Martin-Rivera, L.; Herrera, E. S.; Albar, J. P.; Blasco, M. A. A. Expression of mouse telomerase catalytic subunit in embryos and adult tissues. Proc. Natl. Acad. Sci. USA 1998, 95, 10471-10477. [CrossRef].
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 10471-10477
-
-
Martin-Rivera, L.1
Herrera, E.S.2
Albar, J.P.3
Blasco, M.A.A.4
-
9
-
-
0029040101
-
Developmental and tissue-specific regulation of mouse telomerase and telomere length
-
[CrossRef] [PubMed]
-
Prowse, K. R.; Greider, C. W. Developmental and tissue-specific regulation of mouse telomerase and telomere length. Proc. Natl. Acad. Sci. USA 1995, 92, 4818-4822. [CrossRef] [PubMed].
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4818-4822
-
-
Prowse, K.R.1
Greider, C.W.2
-
10
-
-
0032473931
-
Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation
-
[PubMed]
-
Greenberg, R. A.; Allsopp, R. C.; Chin, L.; Morin, G. B.; DePinho, R. A. Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation. Oncogene 1998, 16, 1723-1730. [PubMed].
-
(1998)
Oncogene
, vol.16
, pp. 1723-1730
-
-
Greenberg, R.A.1
Allsopp, R.C.2
Chin, L.3
Morin, G.B.4
DePinho, R.A.5
-
11
-
-
0025029030
-
Hypervariable ultra-long telomeres in mice
-
[CrossRef] [PubMed]
-
Kipling, D.; Cooke, H. J. Hypervariable ultra-long telomeres in mice. Nature 1990, 347, 400-402. [CrossRef] [PubMed].
-
(1990)
Nature
, vol.347
, pp. 400-402
-
-
Kipling, D.1
Cooke, H.J.2
-
12
-
-
84861879404
-
Genetically engineered mouse models: Closing the gap between preclinical data and trial outcomes
-
[CrossRef] [PubMed]
-
Singh, M.; Murriel, C. L.; Johnson, L. Genetically engineered mouse models: Closing the gap between preclinical data and trial outcomes. Cancer Res. 2012, 72, 2695-2700. [CrossRef] [PubMed].
-
(2012)
Cancer Res
, vol.72
, pp. 2695-2700
-
-
Singh, M.1
Murriel, C.L.2
Johnson, L.3
-
13
-
-
1342288971
-
Opinion: Comparative biology of mouse versus human cells: Modelling human cancer in mice
-
[CrossRef] [PubMed]
-
Rangarajan, A.; Weinberg, R. A. Opinion: Comparative biology of mouse versus human cells: Modelling human cancer in mice. Nat. Rev. Cancer 2003, 3, 952-959. [CrossRef] [PubMed].
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 952-959
-
-
Rangarajan, A.1
Weinberg, R.A.2
-
14
-
-
0036467499
-
Telomerase regulation: Not just flipping the switch
-
[CrossRef]
-
Aisner, D. L.; Wright, W. E.; Shay, J. W. Telomerase regulation: Not just flipping the switch. Curr. Opin. Genet. Dev. 2002, 12, 80-85. [CrossRef].
-
(2002)
Curr. Opin. Genet. Dev
, vol.12
, pp. 80-85
-
-
Aisner, D.L.1
Wright, W.E.2
Shay, J.W.3
-
15
-
-
0033082526
-
Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells
-
[PubMed]
-
Takakura, M.; Kyo, S.; Kanaya, T.; Hirano, H.; Takeda, J.; Yutsudo, M.; Inoue, M. Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells. Cancer Res. 1999, 59, 551-557. [PubMed].
-
(1999)
Cancer Res
, vol.59
, pp. 551-557
-
-
Takakura, M.1
Kyo, S.2
Kanaya, T.3
Hirano, H.4
Takeda, J.5
Yutsudo, M.6
Inoue, M.7
-
16
-
-
0032911694
-
Direct activation of TERT transcription by c-MYC
-
[PubMed]
-
Wu, K. J.; Grandori, C.; Amacker, M.; Simon-Vermot, N.; Polack, A.; Lingner, J.; Dalla-Favera, R. Direct activation of TERT transcription by c-MYC. Nat. Genet. 1999, 21, 220-224. [PubMed].
-
(1999)
Nat. Genet
, vol.21
, pp. 220-224
-
-
Wu, K.J.1
Grandori, C.2
Amacker, M.3
Simon-Vermot, N.4
Polack, A.5
Lingner, J.6
Dalla-Favera, R.7
-
17
-
-
79953142510
-
Chromatin and epigenetic regulation of the telomerase reverse transcriptase gene
-
[CrossRef] [PubMed]
-
Zhu, J.; Zhao, Y.; Wang, S. Chromatin and epigenetic regulation of the telomerase reverse transcriptase gene. Protein Cell 2010, 1, 22-32. [CrossRef] [PubMed].
-
(2010)
Protein Cell
, vol.1
, pp. 22-32
-
-
Zhu, J.1
Zhao, Y.2
Wang, S.3
-
18
-
-
11244349707
-
The hTERT gene is embedded in a nuclease-resistant chromatin domain
-
[CrossRef] [PubMed]
-
Wang, S.; Zhu, J. The hTERT gene is embedded in a nuclease-resistant chromatin domain. J. Biol. Chem. 2004, 279, 55401-55410. [CrossRef] [PubMed].
-
(2004)
J. Biol. Chem
, vol.279
, pp. 55401-55410
-
-
Wang, S.1
Zhu, J.2
-
19
-
-
0035886806
-
Regulation of human telomerase activity: Repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity
-
[PubMed]
-
Ducrest, A. L.; Amacker, M.; Mathieu, Y. D.; Cuthbert, A. P.; Trott, D. A.; Newbold, R. F.; Nabholz, M.; Lingner, J. Regulation of human telomerase activity: Repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity. Cancer Res. 2001, 61, 7594-7602. [PubMed].
-
(2001)
Cancer Res
, vol.61
, pp. 7594-7602
-
-
Ducrest, A.L.1
Amacker, M.2
Mathieu, Y.D.3
Cuthbert, A.P.4
Trott, D.A.5
Newbold, R.F.6
Nabholz, M.7
Lingner, J.8
-
20
-
-
0038820037
-
Evidence for a relief of repression mechanism for activation of the human telomerase reverse transcriptase promoter
-
[CrossRef] [PubMed]
-
Wang, S.; Zhu, J. Evidence for a relief of repression mechanism for activation of the human telomerase reverse transcriptase promoter. J. Biol. Chem. 2003, 278, 18842-18850. [CrossRef] [PubMed].
-
(2003)
J. Biol. Chem
, vol.278
, pp. 18842-18850
-
-
Wang, S.1
Zhu, J.2
-
21
-
-
33846820098
-
Transcriptional silencing of a novel hTERT reporter locus during in vitro differentiation of mouse embryonic stem cells
-
[CrossRef] [PubMed]
-
Wang, S.; Hu, C.; Zhu, J. Transcriptional silencing of a novel hTERT reporter locus during in vitro differentiation of mouse embryonic stem cells. Mol. Biol. Cell. 2007, 18, 669-677. [CrossRef] [PubMed].
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 669-677
-
-
Wang, S.1
Hu, C.2
Zhu, J.3
-
22
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
[CrossRef] [PubMed]
-
Bodnar, A. G.; Ouellette, M.; Frolkis, M.; Holt, S. E.; Chiu, C. P.; Morin, G. B.; Harley, C. B.; Shay, J. W.; Lichtsteiner, S.; Wright, W. E. Extension of life-span by introduction of telomerase into normal human cells. Science 1998, 279, 349-352. [CrossRef] [PubMed].
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chiu, C.P.5
Morin, G.B.6
Harley, C.B.7
Shay, J.W.8
Lichtsteiner, S.9
Wright, W.E.10
-
23
-
-
65849142585
-
Differential repression of human and mouse TERT genes during cell differentiation
-
[CrossRef] [PubMed]
-
Wang, S.; Zhao, Y.; Hu, C.; Zhu, J. Differential repression of human and mouse TERT genes during cell differentiation. Nucleic Acids Res. 2009, 37, 2618-2629. [CrossRef] [PubMed].
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 2618-2629
-
-
Wang, S.1
Zhao, Y.2
Hu, C.3
Zhu, J.4
-
24
-
-
54249099196
-
Species-specific transcription in mice carrying human chromosome 21
-
[CrossRef] [PubMed]
-
Wilson, M. D.; Barbosa-Morais, N. L.; Schmidt, D.; Conboy, C. M.; Vanes, L.; Tybulewicz, V. L.; Fisher, E. M.; Tavare, S.; Odom, D. T. Species-specific transcription in mice carrying human chromosome 21. Science 2008, 322, 434-438. [CrossRef] [PubMed].
-
(2008)
Science
, vol.322
, pp. 434-438
-
-
Wilson, M.D.1
Barbosa-Morais, N.L.2
Schmidt, D.3
Conboy, C.M.4
Vanes, L.5
Tybulewicz, V.L.6
Fisher, E.M.7
Tavare, S.8
Odom, D.T.9
-
25
-
-
0042169025
-
Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms
-
[CrossRef] [PubMed]
-
Horikawa, I.; Barrett, J. C. Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms. Carcinogenesis 2003, 24, 1167-1176. [CrossRef] [PubMed].
-
(2003)
Carcinogenesis
, vol.24
, pp. 1167-1176
-
-
Horikawa, I.1
Barrett, J.C.2
-
26
-
-
0035957406
-
Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells
-
[CrossRef] [PubMed]
-
Xu, D.; Popov, N.; Hou, M.; Wang, Q.; Bjorkholm, M.; Gruber, A.; Menkel, A. R.; Henriksson, M. Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells. Proc. Natl. Acad. Sci. USA 2001, 98, 3826-3831. [CrossRef] [PubMed].
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3826-3831
-
-
Xu, D.1
Popov, N.2
Hou, M.3
Wang, Q.4
Bjorkholm, M.5
Gruber, A.6
Menkel, A.R.7
Henriksson, M.8
-
27
-
-
84921334204
-
Dual roles of c-Myc in the regulation of hTERT gene
-
[CrossRef] [PubMed]
-
Zhao, Y.; Cheng, D.; Wang, S.; Zhu, J. Dual roles of c-Myc in the regulation of hTERT gene. Nucleic Acids Res. 2014, 42, 10385-10398. [CrossRef] [PubMed].
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 10385-10398
-
-
Zhao, Y.1
Cheng, D.2
Wang, S.3
Zhu, J.4
-
28
-
-
0037821661
-
Multiple tumor suppressor pathways negatively regulate telomerase
-
[CrossRef]
-
Lin, S. Y.; Elledge, S. J. Multiple tumor suppressor pathways negatively regulate telomerase. Cell 2003, 113, 881-889. [CrossRef].
-
(2003)
Cell
, vol.113
, pp. 881-889
-
-
Lin, S.Y.1
Elledge, S.J.2
-
29
-
-
0343673898
-
Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1
-
[PubMed]
-
Gunes, C.; Lichtsteiner, S.; Vasserot, A. P.; Englert, C. Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1. Cancer Res. 2000, 60, 2116-2121. [PubMed].
-
(2000)
Cancer Res
, vol.60
, pp. 2116-2121
-
-
Gunes, C.1
Lichtsteiner, S.2
Vasserot, A.P.3
Englert, C.4
-
30
-
-
0033127516
-
Expression of Mad1 protein inhibits proliferation of cancer cells and inversely correlated with Myc protein expression in primary gastric cancer
-
[CrossRef] [PubMed]
-
Han, S.; Park, K.; Kim, H. Y.; Lee, M. S.; Kim, H. J.; Kim, Y. D. Expression of Mad1 protein inhibits proliferation of cancer cells and inversely correlated with Myc protein expression in primary gastric cancer. Oncol. Rep. 1999, 6, 569-574. [CrossRef] [PubMed].
-
(1999)
Oncol. Rep
, vol.6
, pp. 569-574
-
-
Han, S.1
Park, K.2
Kim, H.Y.3
Lee, M.S.4
Kim, H.J.5
Kim, Y.D.6
-
31
-
-
70350464148
-
The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription
-
[CrossRef] [PubMed]
-
Chou, C. K.; Lee, D. F.; Sun, H. L.; Li, L. Y.; Lin, C. Y.; Huang, W. C.; Hsu, J. M.; Kuo, H. P.; Yamaguchi, H.; Wang, Y. N.; et al. The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription. Mol. Carcinog. 2009, 48, 1048-1058. [CrossRef] [PubMed].
-
(2009)
Mol. Carcinog
, vol.48
, pp. 1048-1058
-
-
Chou, C.K.1
Lee, D.F.2
Sun, H.L.3
Li, L.Y.4
Lin, C.Y.5
Huang, W.C.6
Hsu, J.M.7
Kuo, H.P.8
Yamaguchi, H.9
Wang, Y.N.10
-
32
-
-
0035394055
-
E2F-1 represses transcription of the human telomerase reverse transcriptase gene
-
[CrossRef] [PubMed]
-
Crowe, D. L.; Nguyen, D. C.; Tsang, K. J.; Kyo, S. E2F-1 represses transcription of the human telomerase reverse transcriptase gene. Nucleic Acids Res. 2001, 29, 2789-2794. [CrossRef] [PubMed].
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 2789-2794
-
-
Crowe, D.L.1
Nguyen, D.C.2
Tsang, K.J.3
Kyo, S.4
-
33
-
-
84973922207
-
The TERT promoter SNP rs2853669 decreases E2F1 transcription factor binding and increases mortality and recurrence risks in liver cancer
-
[CrossRef] [PubMed]
-
Ko, E.; Seo, H. W.; Jung, E. S.; Kim, B. H.; Jung, G. The TERT promoter SNP rs2853669 decreases E2F1 transcription factor binding and increases mortality and recurrence risks in liver cancer. Oncotarget 2016, 7, 684-699. [CrossRef] [PubMed].
-
(2016)
Oncotarget
, vol.7
, pp. 684-699
-
-
Ko, E.1
Seo, H.W.2
Jung, E.S.3
Kim, B.H.4
Jung, G.5
-
34
-
-
34548381748
-
"Myc'ed Messages": Myc Induces Transcription of E2F1 while Inhibiting Its Translation via a microRNA Polycistron
-
[CrossRef] [PubMed]
-
Coller, H. A.; Forman, J. J.; Legesse-Miller, A. "Myc'ed Messages": Myc Induces Transcription of E2F1 while Inhibiting Its Translation via a microRNA Polycistron. PLoS Genet. 2007, 3, 1329-1334. [CrossRef] [PubMed].
-
(2007)
PLoS Genet
, vol.3
, pp. 1329-1334
-
-
Coller, H.A.1
Forman, J.J.2
Legesse-Miller, A.3
-
35
-
-
84855261286
-
E2F1: A potential negative regulator of hTERT transcription in normal cells upon activation of oncogenic c-Myc
-
[CrossRef] [PubMed]
-
Zhang, Y.; Chen, L.; Yang, S.; Fang, D. E2F1: A potential negative regulator of hTERT transcription in normal cells upon activation of oncogenic c-Myc. Med. Sci. Monit. 2012, 18, RA12-RA15. [CrossRef] [PubMed].
-
(2012)
Med. Sci. Monit
, vol.18
, pp. RA12-RA15
-
-
Zhang, Y.1
Chen, L.2
Yang, S.3
Fang, D.4
-
36
-
-
84923068177
-
E2F1 acts as a negative feedback regulator of c-Mycinduced hTERT transcription during tumorigenesis
-
[PubMed]
-
Zhang, Y.; Zhang, A.; Shen, C.; Zhang, B.; Rao, Z.; Wang, R.; Yang, S.; Ning, S.; Mao, G.; Fang, D. E2F1 acts as a negative feedback regulator of c-Mycinduced hTERT transcription during tumorigenesis. Oncol. Rep. 2014, 32, 1273-1280. [PubMed].
-
(2014)
Oncol. Rep
, vol.32
, pp. 1273-1280
-
-
Zhang, Y.1
Zhang, A.2
Shen, C.3
Zhang, B.4
Rao, Z.5
Wang, R.6
Yang, S.7
Ning, S.8
Mao, G.9
Fang, D.10
-
37
-
-
33646435322
-
E2F1 and telomerase: Alliance in the dark side
-
[CrossRef] [PubMed]
-
Alonso, M. M.; Fueyo, J.; Yung, W. K.; Gomez-Manzano, C. E2F1 and telomerase: alliance in the dark side. Cell Cycle 2006, 5, 930-935. [CrossRef] [PubMed].
-
(2006)
Cell Cycle
, vol.5
, pp. 930-935
-
-
Alonso, M.M.1
Fueyo, J.2
Yung, W.K.3
Gomez-Manzano, C.4
-
38
-
-
27944476391
-
Expression of transcription factor E2F1 and telomerase in glioblastomas: Mechanistic linkage and prognostic significance
-
[CrossRef] [PubMed]
-
Alonso, M. M.; Fueyo, J.; Shay, J. W.; Aldape, K. D.; Jiang, H.; Lee, O. H.; Johnson, D. G.; Xu, J.; Kondo, Y.; Kanzawa, T.; et al. Expression of transcription factor E2F1 and telomerase in glioblastomas: Mechanistic linkage and prognostic significance. J. Natl. Cancer Inst. 2005, 97, 1589-1600. [CrossRef] [PubMed].
-
(2005)
J. Natl. Cancer Inst
, vol.97
, pp. 1589-1600
-
-
Alonso, M.M.1
Fueyo, J.2
Shay, J.W.3
Aldape, K.D.4
Jiang, H.5
Lee, O.H.6
Johnson, D.G.7
Xu, J.8
Kondo, Y.9
Kanzawa, T.10
-
39
-
-
84978470617
-
Malignant Gliomas: Role of E2F1 Transcription Factor
-
Alonso, M. M.; Fueyo, J.; Gomez-Manzano, C. Malignant Gliomas: Role of E2F1 Transcription Factor. Tumors Cent. Nervous Syst. 2011, 1, 89-97.
-
(2011)
Tumors Cent. Nervous Syst
, vol.1
, pp. 89-97
-
-
Alonso, M.M.1
Fueyo, J.2
Gomez-Manzano, C.3
-
40
-
-
84940448352
-
Involvement of transcription repressor Snail in the regulation of human telomerase reverse transcriptase (hTERT) by transforming growth factor-beta
-
[CrossRef] [PubMed]
-
Yoo, Y. S.; Park, S.; Gwak, J.; Ju, B. G.; Oh, S. Involvement of transcription repressor Snail in the regulation of human telomerase reverse transcriptase (hTERT) by transforming growth factor-beta. Biochem. Biophys. Res. Commun. 2015, 465, 131-136. [CrossRef] [PubMed].
-
(2015)
Biochem. Biophys. Res. Commun
, vol.465
, pp. 131-136
-
-
Yoo, Y.S.1
Park, S.2
Gwak, J.3
Ju, B.G.4
Oh, S.5
-
41
-
-
49749139661
-
Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers
-
[CrossRef] [PubMed]
-
Kyo, S.; Takakura, M.; Fujiwara, T.; Inoue, M. Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers. Cancer Sci. 2008, 99, 1528-1538. [CrossRef] [PubMed].
-
(2008)
Cancer Sci
, vol.99
, pp. 1528-1538
-
-
Kyo, S.1
Takakura, M.2
Fujiwara, T.3
Inoue, M.4
-
42
-
-
77649124776
-
Distinct and temporal roles of nucleosomal remodeling and histone deacetylation in the repression of the hTERT gene
-
[CrossRef] [PubMed]
-
Wang, S.; Hu, C.; Zhu, J. Distinct and temporal roles of nucleosomal remodeling and histone deacetylation in the repression of the hTERT gene. Mol. Biol. Cell. 2010, 21, 821-832. [CrossRef] [PubMed].
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 821-832
-
-
Wang, S.1
Hu, C.2
Zhu, J.3
-
43
-
-
84858750992
-
Regulation of the human catalytic subunit of telomerase (hTERT)
-
[CrossRef] [PubMed]
-
Daniel, M.; Peek, G. W.; Tollefsbol, T. O. Regulation of the human catalytic subunit of telomerase (hTERT). Gene 2012, 498, 135-146. [CrossRef] [PubMed].
-
(2012)
Gene
, vol.498
, pp. 135-146
-
-
Daniel, M.1
Peek, G.W.2
Tollefsbol, T.O.3
-
44
-
-
0034680840
-
Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells
-
[CrossRef] [PubMed]
-
Cong, Y. S.; Bacchetti, S. Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells. J. Biol. Chem. 2000, 275, 35665-35668. [CrossRef] [PubMed].
-
(2000)
J. Biol. Chem
, vol.275
, pp. 35665-35668
-
-
Cong, Y.S.1
Bacchetti, S.2
-
45
-
-
84949640899
-
Human Telomerase Reverse Transcriptase (hTERT) Transcription Requires Sp1/Sp3 Binding to the Promoter and a Permissive Chromatin Environment
-
[CrossRef] [PubMed]
-
Cheng, D.; Zhao, Y.; Wang, S.; Jia, W.; Kang, J.; Zhu, J. Human Telomerase Reverse Transcriptase (hTERT) Transcription Requires Sp1/Sp3 Binding to the Promoter and a Permissive Chromatin Environment. J. Biol. Chem. 2015, 290, 30193-30203. [CrossRef] [PubMed].
-
(2015)
J. Biol. Chem
, vol.290
, pp. 30193-30203
-
-
Cheng, D.1
Zhao, Y.2
Wang, S.3
Jia, W.4
Kang, J.5
Zhu, J.6
-
46
-
-
0036142690
-
CpG island methylation of the hTERT promoter is associated with lower telomerase activity in B-cell lymphocytic leukemia
-
[CrossRef]
-
Bechter, O. E.; Eisterer, W.; Dlaska, M.; Kühr, T.; Thaler, J. CpG island methylation of the hTERT promoter is associated with lower telomerase activity in B-cell lymphocytic leukemia. Exp. Hematol. 2002, 30, 26-33. [CrossRef].
-
(2002)
Exp. Hematol
, vol.30
, pp. 26-33
-
-
Bechter, O.E.1
Eisterer, W.2
Dlaska, M.3
Kühr, T.4
Thaler, J.5
-
47
-
-
84959566355
-
Telomerase Expression by Aberrant Methylation of the TERT Promoter in Melanoma Arising in Giant Congenital Nevi
-
[CrossRef] [PubMed]
-
Fan, Y.; Lee, S.; Wu, G.; Easton, J.; Yergeau, D.; Dummer, R.; Vogel, P.; Kirkwood, J. M.; Barnhill, R. L.; Pappo, A.; et al. Telomerase Expression by Aberrant Methylation of the TERT Promoter in Melanoma Arising in Giant Congenital Nevi. J. Investig. Dermatol. 2016, 136, 339-342. [CrossRef] [PubMed].
-
(2016)
J. Investig. Dermatol
, vol.136
, pp. 339-342
-
-
Fan, Y.1
Lee, S.2
Wu, G.3
Easton, J.4
Yergeau, D.5
Dummer, R.6
Vogel, P.7
Kirkwood, J.M.8
Barnhill, R.L.9
Pappo, A.10
-
48
-
-
84949681589
-
Aberrant methylation of the TERT promoter in esophageal squamous cell carcinoma
-
[CrossRef] [PubMed]
-
Deng, J.; Zhou, D.; Zhang, J.; Chen, Y.; Wang, C.; Liu, Y.; Zhao, K. Aberrant methylation of the TERT promoter in esophageal squamous cell carcinoma. Cancer Genet. 2015, 208, 602-609. [CrossRef] [PubMed].
-
(2015)
Cancer Genet
, vol.208
, pp. 602-609
-
-
Deng, J.1
Zhou, D.2
Zhang, J.3
Chen, Y.4
Wang, C.5
Liu, Y.6
Zhao, K.7
-
49
-
-
84953364559
-
hTERT promoter methylation in pituitary adenomas
-
[CrossRef] [PubMed]
-
Kochling, M.; Ewelt, C.; Furtjes, G.; Peetz-Dienhart, S.; Koos, B.; Hasselblatt, M.; Paulus, W.; Stummer, W.; Brokinkel, B. hTERT promoter methylation in pituitary adenomas. Brain Tumor Pathol. 2016, 33, 27-34. [CrossRef] [PubMed].
-
(2016)
Brain Tumor Pathol
, vol.33
, pp. 27-34
-
-
Kochling, M.1
Ewelt, C.2
Furtjes, G.3
Peetz-Dienhart, S.4
Koos, B.5
Hasselblatt, M.6
Paulus, W.7
Stummer, W.8
Brokinkel, B.9
-
50
-
-
77955818622
-
Robust activation of the human but not mouse telomerase gene during the induction of pluripotency
-
[CrossRef] [PubMed]
-
Mathew, R.; Jia, W.; Sharma, A.; Zhao, Y.; Clarke, L. E.; Cheng, X.; Wang, H.; Salli, U.; Vrana, K. E.; Robertson, G. P.; et al. Robust activation of the human but not mouse telomerase gene during the induction of pluripotency. FASEB J. 2010, 24, 2702-2715. [CrossRef] [PubMed].
-
(2010)
FASEB J
, vol.24
, pp. 2702-2715
-
-
Mathew, R.1
Jia, W.2
Sharma, A.3
Zhao, Y.4
Clarke, L.E.5
Cheng, X.6
Wang, H.7
Salli, U.8
Vrana, K.E.9
Robertson, G.P.10
-
51
-
-
24744436980
-
Lack of telomerase gene expression in alternative lengthening of telomere cells is associated with chromatin remodeling of the hTR and hTERT gene promoters
-
[PubMed]
-
Atkinson, S. P.; Hoare, S. F.; Glasspool, R. M.; Keith, W. N. Lack of telomerase gene expression in alternative lengthening of telomere cells is associated with chromatin remodeling of the hTR and hTERT gene promoters. Cancer Res. 2005, 65, 7585-7590. [PubMed].
-
(2005)
Cancer Res
, vol.65
, pp. 7585-7590
-
-
Atkinson, S.P.1
Hoare, S.F.2
Glasspool, R.M.3
Keith, W.N.4
-
52
-
-
33846422373
-
hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site
-
[CrossRef] [PubMed]
-
Zinn, R. L.; Pruitt, K.; Eguchi, S.; Baylin, S. B.; Herman, J. G. hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site. Cancer Res. 2007, 67, 194-201. [CrossRef] [PubMed].
-
(2007)
Cancer Res
, vol.67
, pp. 194-201
-
-
Zinn, R.L.1
Pruitt, K.2
Eguchi, S.3
Baylin, S.B.4
Herman, J.G.5
-
53
-
-
0034142386
-
Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT)
-
[CrossRef] [PubMed]
-
Kyo, S.; Takakura, M.; Taira, T.; Kanaya, T.; Itoh, H.; Yutsudo, M.; Ariga, H.; Inoue, M. Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT). Nucleic Acids Res. 2000, 28, 669-677. [CrossRef] [PubMed].
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 669-677
-
-
Kyo, S.1
Takakura, M.2
Taira, T.3
Kanaya, T.4
Itoh, H.5
Yutsudo, M.6
Ariga, H.7
Inoue, M.8
-
54
-
-
0033406452
-
Estrogen activates telomerase
-
[PubMed]
-
Kyo, S.; Takakura, M.; Kanaya, T.; Zhuo, W.; Fujimoto, K.; Nishio, Y.; Orimo, A.; Inoue, M. Estrogen activates telomerase. Cancer Res. 1999, 59, 5917-5921. [PubMed].
-
(1999)
Cancer Res
, vol.59
, pp. 5917-5921
-
-
Kyo, S.1
Takakura, M.2
Kanaya, T.3
Zhuo, W.4
Fujimoto, K.5
Nishio, Y.6
Orimo, A.7
Inoue, M.8
-
55
-
-
34548638527
-
Inhibition of estrogen receptor beta-mediated human telomerase reverse transcriptase gene transcription via the suppression of mitogen-activated protein kinase signaling plays an important role in 15-deoxy-Delta(12, 14)-prostaglandin J(2)-induced apoptosis in cancer cells
-
[PubMed]
-
Kondoh, K.; Tsuji, N.; Asanuma, K.; Kobayashi, D.; Watanabe, N. Inhibition of estrogen receptor beta-mediated human telomerase reverse transcriptase gene transcription via the suppression of mitogen-activated protein kinase signaling plays an important role in 15-deoxy-Delta(12, 14)-prostaglandin J(2)-induced apoptosis in cancer cells. Exp. Cell. Res. 2007, 313, 3486-3496. [PubMed].
-
(2007)
Exp. Cell. Res
, vol.313
, pp. 3486-3496
-
-
Kondoh, K.1
Tsuji, N.2
Asanuma, K.3
Kobayashi, D.4
Watanabe, N.5
-
56
-
-
48049098413
-
Estrogen receptor-alpha and endothelial nitric oxide synthase nuclear complex regulates transcription of human telomerase
-
[CrossRef] [PubMed]
-
Grasselli, A.; Nanni, S.; Colussi, C.; Aiello, A.; Benvenuti, V.; Ragone, G.; Moretti, F.; Sacchi, A.; Bacchetti, S.; Gaetano, C.; et al. Estrogen receptor-alpha and endothelial nitric oxide synthase nuclear complex regulates transcription of human telomerase. Circ. Res. 2008, 103, 34-42. [CrossRef] [PubMed].
-
(2008)
Circ. Res
, vol.103
, pp. 34-42
-
-
Grasselli, A.1
Nanni, S.2
Colussi, C.3
Aiello, A.4
Benvenuti, V.5
Ragone, G.6
Moretti, F.7
Sacchi, A.8
Bacchetti, S.9
Gaetano, C.10
-
57
-
-
0037478697
-
Human papillomavirus E6 and Myc proteins associate in vivo and bind to and cooperatively activate the telomerase reverse transcriptase promoter
-
[CrossRef] [PubMed]
-
Veldman, T.; Liu, X.; Yuan, H.; Schlegel, R. Human papillomavirus E6 and Myc proteins associate in vivo and bind to and cooperatively activate the telomerase reverse transcriptase promoter. Proc. Natl. Acad. Sci. USA 2003, 100, 8211-8216. [CrossRef] [PubMed].
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8211-8216
-
-
Veldman, T.1
Liu, X.2
Yuan, H.3
Schlegel, R.4
-
58
-
-
67449093864
-
NFX1-123 increases hTERT expression and telomerase activity posttranscriptionally in human papillomavirus type 16 E6 keratinocytes
-
[CrossRef] [PubMed]
-
Katzenellenbogen, R. A.; Vliet-Gregg, P.; Xu, M.; Galloway, D. A. NFX1-123 increases hTERT expression and telomerase activity posttranscriptionally in human papillomavirus type 16 E6 keratinocytes. J. Virol. 2009, 83, 6446-6456. [CrossRef] [PubMed].
-
(2009)
J. Virol
, vol.83
, pp. 6446-6456
-
-
Katzenellenbogen, R.A.1
Vliet-Gregg, P.2
Xu, M.3
Galloway, D.A.4
-
59
-
-
84874191269
-
TERT promoter mutations in familial and sporadic melanoma
-
[CrossRef] [PubMed]
-
Horn, S.; Figl, A.; Rachakonda, P. S.; Fischer, C.; Sucker, A.; Gast, A.; Kadel, S.; Moll, I.; Nagore, E.; Hemminki, K.; et al. TERT promoter mutations in familial and sporadic melanoma. Science 2013, 339, 959-961. [CrossRef] [PubMed].
-
(2013)
Science
, vol.339
, pp. 959-961
-
-
Horn, S.1
Figl, A.2
Rachakonda, P.S.3
Fischer, C.4
Sucker, A.5
Gast, A.6
Kadel, S.7
Moll, I.8
Nagore, E.9
Hemminki, K.10
-
60
-
-
84923785114
-
TERT promoter mutations and telomerase reactivation in urothelial cancer
-
[CrossRef] [PubMed]
-
Borah, S.; Xi, L.; Zaug, A. J.; Powell, N. M.; Dancik, G.; Cohen, S. B.; Costello, J. C.; Theodorescu, D.; Cech, T. R. TERT promoter mutations and telomerase reactivation in urothelial cancer. Science 2015, 347, 1006-1010. [CrossRef] [PubMed].
-
(2015)
Science
, vol.347
, pp. 1006-1010
-
-
Borah, S.1
Xi, L.2
Zaug, A.J.3
Powell, N.M.4
Dancik, G.5
Cohen, S.B.6
Costello, J.C.7
Theodorescu, D.8
Cech, T.R.9
-
61
-
-
84910028345
-
Telomerase in differentiated thyroid cancer: Promoter mutations, expression and localization
-
[CrossRef] [PubMed]
-
Muzza, M.; Colombo, C.; Rossi, S.; Tosi, D.; Cirello, V.; Perrino, M.; de Leo, S.; Magnani, E.; Pignatti, E.; Vigo, B.; et al. Telomerase in differentiated thyroid cancer: Promoter mutations, expression and localization. Mol. Cell Endocrinol. 2015, 399, 288-295. [CrossRef] [PubMed].
-
(2015)
Mol. Cell Endocrinol
, vol.399
, pp. 288-295
-
-
Muzza, M.1
Colombo, C.2
Rossi, S.3
Tosi, D.4
Cirello, V.5
Perrino, M.6
de Leo, S.7
Magnani, E.8
Pignatti, E.9
Vigo, B.10
-
62
-
-
84877954369
-
Histone Methyltransferase Inhibitors: Novel Epigenetic Agents for Cancer Treatment
-
[CrossRef] [PubMed]
-
Zagni, C.; Chiacchi, U.; Rescifina, A. Histone Methyltransferase Inhibitors: Novel Epigenetic Agents for Cancer Treatment. Curr. Med. Chem. 2013, 20, 167-185. [CrossRef] [PubMed].
-
(2013)
Curr. Med. Chem
, vol.20
, pp. 167-185
-
-
Zagni, C.1
Chiacchi, U.2
Rescifina, A.3
-
63
-
-
84946567748
-
A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression
-
[CrossRef] [PubMed]
-
Xi, L.; Schmidt, J. C.; Zaug, A. J.; Ascarrunz, D. R.; Cech, T. R. A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression. Genome Biol. 2015, 16, 231-247. [CrossRef] [PubMed].
-
(2015)
Genome Biol
, vol.16
, pp. 231-247
-
-
Xi, L.1
Schmidt, J.C.2
Zaug, A.J.3
Ascarrunz, D.R.4
Cech, T.R.5
-
64
-
-
84930677573
-
Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer
-
Bell, R. J.; Rube, H. T.; Kreig, A.; Mancini, A.; Fouse, S. D.; Nagarajan, R. P.; Choi, S.; Hong, C.; He, D.; Pekmezci, M.; et al. Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer. Science 2015, 348, 1036-1039.
-
(2015)
Science
, vol.348
, pp. 1036-1039
-
-
Bell, R.J.1
Rube, H.T.2
Kreig, A.3
Mancini, A.4
Fouse, S.D.5
Nagarajan, R.P.6
Choi, S.7
Hong, C.8
He, D.9
Pekmezci, M.10
-
65
-
-
84946712059
-
Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers
-
[CrossRef] [PubMed]
-
Stern, J. L.; Theodorescu, D.; Vogelstein, B.; Papadopoulos, N.; Cech, T. R. Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers. Genes Dev. 2015, 29, 2219-2224. [CrossRef] [PubMed].
-
(2015)
Genes Dev
, vol.29
, pp. 2219-2224
-
-
Stern, J.L.1
Theodorescu, D.2
Vogelstein, B.3
Papadopoulos, N.4
Cech, T.R.5
-
66
-
-
84942986703
-
Non-canonical NF-kappaB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation
-
[CrossRef] [PubMed]
-
Li, Y.; Zhou, Q. L.; Sun, W.; Chandrasekharan, P.; Cheng, H. S.; Ying, Z.; Lakshmanan, M.; Raju, A.; Tenen, D. G.; Cheng, S. Y.; et al. Non-canonical NF-kappaB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation. Nat. Cell Biol. 2015, 17, 1327-1338. [CrossRef] [PubMed].
-
(2015)
Nat. Cell Biol
, vol.17
, pp. 1327-1338
-
-
Li, Y.1
Zhou, Q.L.2
Sun, W.3
Chandrasekharan, P.4
Cheng, H.S.5
Ying, Z.6
Lakshmanan, M.7
Raju, A.8
Tenen, D.G.9
Cheng, S.Y.10
-
67
-
-
84949788402
-
TERT promoter mutations and monoallelic activation of TERT in cancer
-
[CrossRef] [PubMed]
-
Huang, F. W.; Bielski, C. M.; Rinne, M. L.; Hahn, W. C.; Sellers, W. R.; Stegmeier, F.; Garraway, L. A.; Kryukov, G. V. TERT promoter mutations and monoallelic activation of TERT in cancer. Oncogenesis 2015. [CrossRef] [PubMed].
-
(2015)
Oncogenesis
-
-
Huang, F.W.1
Bielski, C.M.2
Rinne, M.L.3
Hahn, W.C.4
Sellers, W.R.5
Stegmeier, F.6
Garraway, L.A.7
Kryukov, G.V.8
-
68
-
-
84875717832
-
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
-
[CrossRef] [PubMed]
-
Bojesen, S. E.; Pooley, K. A.; Johnatty, S. E.; Beesley, J.; Michailidou, K.; Tyrer, J. P.; Edwards, S. L.; Pickett, H. A.; Shen, H. C.; Smart, C. E.; et al. Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat. Genet. 2013, 45, 371-384. [CrossRef] [PubMed].
-
(2013)
Nat. Genet
, vol.45
, pp. 371-384
-
-
Bojesen, S.E.1
Pooley, K.A.2
Johnatty, S.E.3
Beesley, J.4
Michailidou, K.5
Tyrer, J.P.6
Edwards, S.L.7
Pickett, H.A.8
Shen, H.C.9
Smart, C.E.10
-
69
-
-
84896737631
-
Association between the telomerase reverse transcriptase (TERT) rs2736098 polymorphism and cancer risk: Evidence from a case-control study of non-small-cell lung cancer and a meta-analysis
-
[CrossRef] [PubMed]
-
Wu, H.; Qiao, N.; Wang, Y.; Jiang, M.; Wang, S.; Wang, C.; Hu, L. Association between the telomerase reverse transcriptase (TERT) rs2736098 polymorphism and cancer risk: evidence from a case-control study of non-small-cell lung cancer and a meta-analysis. PLoS ONE 2013. [CrossRef] [PubMed].
-
(2013)
PLoS ONE
-
-
Wu, H.1
Qiao, N.2
Wang, Y.3
Jiang, M.4
Wang, S.5
Wang, C.6
Hu, L.7
-
70
-
-
84874234171
-
hTERT rs2736098 genetic variants and susceptibility of hepatocellular carcinoma in the Chinese population: A case-control study
-
[CrossRef]
-
Zhang, C.; Tian, Y. P.; Wang, Y.; Guo, F. H.; Qin, J. F.; Ni, H. hTERT rs2736098 genetic variants and susceptibility of hepatocellular carcinoma in the Chinese population: A case-control study. Hepatobiliary Pancreat Dis. Int. 2013, 12, 74-79. [CrossRef].
-
(2013)
Hepatobiliary Pancreat Dis. Int
, vol.12
, pp. 74-79
-
-
Zhang, C.1
Tian, Y.P.2
Wang, Y.3
Guo, F.H.4
Qin, J.F.5
Ni, H.6
-
71
-
-
84874012729
-
Association of TERT rs2736098 polymorphism with cancer risk: A meta-analysis
-
[CrossRef]
-
Zhang, X. J.; Xu, Z.; Gong, Y. L.; Tang, C. J.; Chen, J. F. Association of TERT rs2736098 polymorphism with cancer risk: A meta-analysis. Asian Pac. J. Cancer Prev. 2012, 13, 4943-4946. [CrossRef].
-
(2012)
Asian Pac. J. Cancer Prev
, vol.13
, pp. 4943-4946
-
-
Zhang, X.J.1
Xu, Z.2
Gong, Y.L.3
Tang, C.J.4
Chen, J.F.5
-
72
-
-
84906268015
-
Association between telomerase reverse transcriptase rs2736100 polymorphism and risk of glioma
-
[CrossRef] [PubMed]
-
Zhou, P.; Wei, L.; Xia, X.; Shao, N.; Qian, X.; Yang, Y. Association between telomerase reverse transcriptase rs2736100 polymorphism and risk of glioma. J. Surg. Res. 2014, 191, 156-160. [CrossRef] [PubMed].
-
(2014)
J. Surg. Res
, vol.191
, pp. 156-160
-
-
Zhou, P.1
Wei, L.2
Xia, X.3
Shao, N.4
Qian, X.5
Yang, Y.6
-
73
-
-
84946815895
-
TERT Polymorphism rs2736100-C Is Associated with EGFR Mutation-Positive Non-Small Cell Lung Cancer
-
[CrossRef] [PubMed]
-
Wei, R.; Cao, L.; Pu, H.; Wang, H.; Zheng, Y.; Niu, X.; Weng, X.; Zhang, H.; Favus, M. J.; Zhang, L.; et al. TERT Polymorphism rs2736100-C Is Associated with EGFR Mutation-Positive Non-Small Cell Lung Cancer. Clin. Cancer Res. 2015, 21, 5173-5180. [CrossRef] [PubMed].
-
(2015)
Clin. Cancer Res
, vol.21
, pp. 5173-5180
-
-
Wei, R.1
Cao, L.2
Pu, H.3
Wang, H.4
Zheng, Y.5
Niu, X.6
Weng, X.7
Zhang, H.8
Favus, M.J.9
Zhang, L.10
-
74
-
-
84865863668
-
The TERT variant rs2736100 is associated with colorectal cancer risk
-
[CrossRef] [PubMed]
-
Kinnersley, B.; Migliorini, G.; Broderick, P.; Whiffin, N.; Dobbins, S. E.; Casey, G.; Hopper, J.; Sieber, O.; Lipton, L.; Kerr, D. J.; et al. The TERT variant rs2736100 is associated with colorectal cancer risk. Br. J. Cancer 2012, 107, 1001-1008. [CrossRef] [PubMed].
-
(2012)
Br. J. Cancer
, vol.107
, pp. 1001-1008
-
-
Kinnersley, B.1
Migliorini, G.2
Broderick, P.3
Whiffin, N.4
Dobbins, S.E.5
Casey, G.6
Hopper, J.7
Sieber, O.8
Lipton, L.9
Kerr, D.J.10
-
75
-
-
84875436593
-
Longer telomere length in peripheral white blood cells is associated with risk of lung cancer and the rs2736100 (CLPTM1L-TERT) polymorphism in a prospective cohort study among women in China
-
[CrossRef]
-
Lan, Q.; Cawthon, R.; Gao, Y.; Hu, W.; Hosgood, H. D., 3rd; Barone-Adesi, F.; Ji, B. T.; Bassig, B.; Chow, W. H.; Shu, X.; et al. Longer telomere length in peripheral white blood cells is associated with risk of lung cancer and the rs2736100 (CLPTM1L-TERT) polymorphism in a prospective cohort study among women in China. PLoS ONE 2013. [CrossRef].
-
(2013)
PLoS ONE
-
-
Lan, Q.1
Cawthon, R.2
Gao, Y.3
Hu, W.4
Hosgood, H.D.5
Barone-Adesi, F.6
Ji, B.T.7
Bassig, B.8
Chow, W.H.9
Shu, X.10
-
76
-
-
84878451270
-
Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression
-
[CrossRef]
-
Kote-Jarai, Z.; Saunders, E. J.; Leongamornlert, D. A.; Tymrakiewicz, M.; Dadaev, T.; Jugurnauth-Little, S.; Ross-Adams, H.; Al Olama, A. A.; Benlloch, S.; Halim, S.; et al. Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression. Hum. Mol. Genet. 2013. [CrossRef].
-
(2013)
Hum. Mol. Genet
-
-
Kote-Jarai, Z.1
Saunders, E.J.2
Leongamornlert, D.A.3
Tymrakiewicz, M.4
Dadaev, T.5
Jugurnauth-Little, S.6
Ross-Adams, H.7
Al Olama, A.A.8
Benlloch, S.9
Halim, S.10
-
77
-
-
84961644849
-
The prognostic impact of TERT promoter mutations in glioblastomas is modified by the rs2853669 single nucleotide polymorphism
-
[CrossRef] [PubMed]
-
Batista, R.; Cruvinel-Carloni, A.; Vinagre, J.; Peixoto, J.; Catarino, T. A.; Campanella, N. C.; Menezes, W.; Becker, A. P.; de Almeida, G. C.; Matsushita, M. M.; et al. The prognostic impact of TERT promoter mutations in glioblastomas is modified by the rs2853669 single nucleotide polymorphism. Int. J. Cancer 2016, 414-423. [CrossRef] [PubMed].
-
(2016)
Int. J. Cancer
, pp. 414-423
-
-
Batista, R.1
Cruvinel-Carloni, A.2
Vinagre, J.3
Peixoto, J.4
Catarino, T.A.5
Campanella, N.C.6
Menezes, W.7
Becker, A.P.8
de Almeida, G.C.9
Matsushita, M.M.10
-
78
-
-
84886390673
-
TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphism
-
[CrossRef] [PubMed]
-
Rachakonda, P. S.; Hosen, I.; de Verdier, P. J.; Fallah, M.; Heidenreich, B.; Ryk, C.; Wiklund, N. P.; Steineck, G.; Schadendorf, D.; Hemminki, K.; et al. TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphism. Proc. Natl. Acad. Sci. USA 2013, 110, 17426-17431. [CrossRef] [PubMed].
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 17426-17431
-
-
Rachakonda, P.S.1
Hosen, I.2
de Verdier, P.J.3
Fallah, M.4
Heidenreich, B.5
Ryk, C.6
Wiklund, N.P.7
Steineck, G.8
Schadendorf, D.9
Hemminki, K.10
-
79
-
-
84874189784
-
Highly Recurrent TERT Promoter Mutations in Human Melanoma
-
[CrossRef] [PubMed]
-
Huang, F. W.; Hodis, E.; Xu, M. J.; Kryukov, G. V.; Chin, L.; Garraway, L. A. Highly Recurrent TERT Promoter Mutations in Human Melanoma. Science 2013, 339, 957-958. [CrossRef] [PubMed].
-
(2013)
Science
, vol.339
, pp. 957-958
-
-
Huang, F.W.1
Hodis, E.2
Xu, M.J.3
Kryukov, G.V.4
Chin, L.5
Garraway, L.A.6
-
80
-
-
84922513709
-
TERT promoter mutations: A novel independent prognostic factor in primary glioblastomas
-
[CrossRef] [PubMed]
-
Simon, M.; Hosen, I.; Gousias, K.; Rachakonda, S.; Heidenreich, B.; Gessi, M.; Schramm, J.; Hemminki, K.; Waha, A.; Kumar, R. TERT promoter mutations: A novel independent prognostic factor in primary glioblastomas. Neuro-Oncol. 2015, 17, 45-52. [CrossRef] [PubMed].
-
(2015)
Neuro-Oncol
, vol.17
, pp. 45-52
-
-
Simon, M.1
Hosen, I.2
Gousias, K.3
Rachakonda, S.4
Heidenreich, B.5
Gessi, M.6
Schramm, J.7
Hemminki, K.8
Waha, A.9
Kumar, R.10
-
81
-
-
84884524540
-
Frequency of TERT promoter mutations in human cancers
-
[CrossRef] [PubMed]
-
Vinagre, J.; Almeida, A.; Populo, H.; Batista, R.; Lyra, J.; Pinto, V.; Coelho, R.; Celestino, R.; Prazeres, H.; Lima, L.; et al. Frequency of TERT promoter mutations in human cancers. Nat. Commun. 2013. [CrossRef] [PubMed].
-
(2013)
Nat. Commun
-
-
Vinagre, J.1
Almeida, A.2
Populo, H.3
Batista, R.4
Lyra, J.5
Pinto, V.6
Coelho, R.7
Celestino, R.8
Prazeres, H.9
Lima, L.10
-
82
-
-
84937923740
-
TERT promoter mutations and polymorphisms as prognostic factors in primary glioblastoma
-
[CrossRef] [PubMed]
-
Mosrati, M. A.; Malmström, A.; Lysiak, M.; Krysztofiak, A.; Hallbeck, M.; Milos, P.; Hallbeck, A.-L. TERT promoter mutations and polymorphisms as prognostic factors in primary glioblastoma. Oncotarget 2015, 6, 16663-16673. [CrossRef] [PubMed].
-
(2015)
Oncotarget
, vol.6
, pp. 16663-16673
-
-
Mosrati, M.A.1
Malmström, A.2
Lysiak, M.3
Krysztofiak, A.4
Hallbeck, M.5
Milos, P.6
Hallbeck, A.-L.7
-
83
-
-
84956703933
-
TERT promoter mutations and rs2853669 polymorphism: Prognostic impact and interactions with common alterations in glioblastomas
-
[CrossRef] [PubMed]
-
Nencha, U.; Rahimian, A.; Giry, M.; Sechi, A.; Mokhtari, K.; Polivka, M.; Schmitt, Y.; di Stefano, A. L.; Alentorn, A.; Labussiere, M.; et al. TERT promoter mutations and rs2853669 polymorphism: Prognostic impact and interactions with common alterations in glioblastomas. J. Neurooncol. 2016, 126, 441-446. [CrossRef] [PubMed].
-
(2016)
J. Neurooncol
, vol.126
, pp. 441-446
-
-
Nencha, U.1
Rahimian, A.2
Giry, M.3
Sechi, A.4
Mokhtari, K.5
Polivka, M.6
Schmitt, Y.7
di Stefano, A.L.8
Alentorn, A.9
Labussiere, M.10
-
84
-
-
84924341965
-
TERT promoter mutations in clear cell renal cell carcinoma
-
[CrossRef] [PubMed]
-
Hosen, I.; Rachakonda, P. S.; Heidenreich, B.; Sitaram, R. T.; Ljungberg, B.; Roos, G.; Hemminki, K.; Kumar, R. TERT promoter mutations in clear cell renal cell carcinoma. Int. J. Cancer 2015, 136, 2448-2452. [CrossRef] [PubMed].
-
(2015)
Int. J. Cancer
, vol.136
, pp. 2448-2452
-
-
Hosen, I.1
Rachakonda, P.S.2
Heidenreich, B.3
Sitaram, R.T.4
Ljungberg, B.5
Roos, G.6
Hemminki, K.7
Kumar, R.8
-
85
-
-
77954700718
-
Prognostic significance of telomerase polymorphism in non-small cell lung cancer
-
[CrossRef] [PubMed]
-
Catarino, R.; Araujo, A.; Coelho, A.; Gomes, M.; Nogueira, A.; Lopes, C.; Medeiros, R. M. Prognostic significance of telomerase polymorphism in non-small cell lung cancer. Clin. Cancer Res. 2010, 16, 3706-3712. [CrossRef] [PubMed].
-
(2010)
Clin. Cancer Res
, vol.16
, pp. 3706-3712
-
-
Catarino, R.1
Araujo, A.2
Coelho, A.3
Gomes, M.4
Nogueira, A.5
Lopes, C.6
Medeiros, R.M.7
-
86
-
-
84872145398
-
TERT polymorphisms modify the risk of acute lymphoblastic leukemia in Chinese children
-
[CrossRef] [PubMed]
-
Sheng, X.; Tong, N.; Tao, G.; Luo, D.; Wang, M.; Fang, Y.; Li, J.; Xu, M.; Zhang, Z.; Wu, D. TERT polymorphisms modify the risk of acute lymphoblastic leukemia in Chinese children. Carcinogenesis 2013, 34, 228-235. [CrossRef] [PubMed].
-
(2013)
Carcinogenesis
, vol.34
, pp. 228-235
-
-
Sheng, X.1
Tong, N.2
Tao, G.3
Luo, D.4
Wang, M.5
Fang, Y.6
Li, J.7
Xu, M.8
Zhang, Z.9
Wu, D.10
-
87
-
-
84925483160
-
Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk
-
[CrossRef] [PubMed]
-
Carvajal-Carmona, L. G.; O'Mara, T. A.; Painter, J. N.; Lose, F. A.; Dennis, J.; Michailidou, K.; Tyrer, J. P.; Ahmed, S.; Ferguson, K.; Healey, C. S.; et al. Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk. Hum. Genet. 2015, 134, 231-245. [CrossRef] [PubMed].
-
(2015)
Hum. Genet
, vol.134
, pp. 231-245
-
-
Carvajal-Carmona, L.G.1
O'Mara, T.A.2
Painter, J.N.3
Lose, F.A.4
Dennis, J.5
Michailidou, K.6
Tyrer, J.P.7
Ahmed, S.8
Ferguson, K.9
Healey, C.S.10
-
88
-
-
84880263616
-
Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4
-
[CrossRef] [PubMed]
-
Scherf, D. B.; Sarkisyan, N.; Jacobsson, H.; Claus, R.; Bermejo, J. L.; Peil, B.; Gu, L.; Muley, T.; Meister, M.; Dienemann, H.; et al. Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4. Oncogene 2013, 32, 3329-3338. [CrossRef] [PubMed].
-
(2013)
Oncogene
, vol.32
, pp. 3329-3338
-
-
Scherf, D.B.1
Sarkisyan, N.2
Jacobsson, H.3
Claus, R.4
Bermejo, J.L.5
Peil, B.6
Gu, L.7
Muley, T.8
Meister, M.9
Dienemann, H.10
-
89
-
-
70349310232
-
Rearrangement of upstream sequences of the hTERT gene during cellular immortalization
-
[CrossRef] [PubMed]
-
Zhao, Y.; Wang, S.; Popova, E. Y.; Grigoryev, S. A.; Zhu, J. Rearrangement of upstream sequences of the hTERT gene during cellular immortalization. Genes Chromosomes Cancer 2009, 48, 963-974. [CrossRef] [PubMed].
-
(2009)
Genes Chromosomes Cancer
, vol.48
, pp. 963-974
-
-
Zhao, Y.1
Wang, S.2
Popova, E.Y.3
Grigoryev, S.A.4
Zhu, J.5
-
90
-
-
84886297667
-
Recurrent pre-existing and acquired DNA copy number alterations, including focal TERT gains, in neuroblastoma central nervous system metastases
-
[CrossRef] [PubMed]
-
Cobrinik, D.; Ostrovnaya, I.; Hassimi, M.; Tickoo, S. K.; Cheung, I. Y.; Cheung, N. K. Recurrent pre-existing and acquired DNA copy number alterations, including focal TERT gains, in neuroblastoma central nervous system metastases. Genes Chromosomes Cancer 2013, 52, 1150-1166. [CrossRef] [PubMed].
-
(2013)
Genes Chromosomes Cancer
, vol.52
, pp. 1150-1166
-
-
Cobrinik, D.1
Ostrovnaya, I.2
Hassimi, M.3
Tickoo, S.K.4
Cheung, I.Y.5
Cheung, N.K.6
-
91
-
-
84945918266
-
Telomerase activation by genomic rearrangements in high-risk neuroblastoma
-
[CrossRef] [PubMed]
-
Peifer, M.; Hertwig, F.; Roels, F.; Dreidax, D.; Gartlgruber, M.; Menon, R.; Kramer, A.; Roncaioli, J. L.; Sand, F.; Heuckmann, J. M.; et al. Telomerase activation by genomic rearrangements in high-risk neuroblastoma. Nature 2015, 526, 700-704. [CrossRef] [PubMed].
-
(2015)
Nature
, vol.526
, pp. 700-704
-
-
Peifer, M.1
Hertwig, F.2
Roels, F.3
Dreidax, D.4
Gartlgruber, M.5
Menon, R.6
Kramer, A.7
Roncaioli, J.L.8
Sand, F.9
Heuckmann, J.M.10
|