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Volumn 42, Issue 16, 2014, Pages 10385-10398

Dual roles of c-Myc in the regulation of hTERT gene

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE; MAX PROTEIN; MYC PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; TRANSCRIPTION FACTOR; UPSTREAM STIMULATORY FACTOR 1; UPSTREAM STIMULATORY FACTOR 2; CHROMATIN; DNA BINDING PROTEIN; HISTONE; MYC PROTEIN, HUMAN; SMALL INTERFERING RNA; TELOMERASE; TERT PROTEIN, HUMAN;

EID: 84921334204     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku721     Document Type: Article
Times cited : (46)

References (48)
  • 1
    • 0024325562 scopus 로고
    • The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
    • Morin, G.B. Morin, G.B. (1989) The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell, 59, 521-529.
    • (1989) Cell , vol.59 , pp. 521-529
    • Morin, G.B.1    Morin, G.B.2
  • 5
    • 0043199578 scopus 로고    scopus 로고
    • Telomerase maintains telomere structure in normal human cells
    • Masutomi, K., Yu, E.Y., Khurts, S., Ben-Porath, I., Currier, J.L., Metz, G.B., Brooks, M.W., Kaneko, S., Murakami, S., and DeCaprio, J.A. et al.Masutomi, K., Yu, E.Y., Khurts, S., Ben-Porath, I., Currier, J.L., Metz, G.B., Brooks, M.W., Kaneko, S., Murakami, S., and DeCaprio, J.A. (2003) Telomerase maintains telomere structure in normal human cells. Cell, 114, 241-253.
    • (2003) Cell , vol.114 , pp. 241-253
    • Masutomi, K.1    Yu, E.Y.2    Khurts, S.3    Ben-Porath, I.4    Currier, J.L.5    Metz, G.B.6    Brooks, M.W.7    Kaneko, S.8    Murakami, S.9    Decaprio, J.A.10
  • 10
    • 0033082526 scopus 로고    scopus 로고
    • Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells
    • Takakura, M., Kyo, S., Kanaya, T., Hirano, H., Takeda, J., Yutsudo, M., and Inoue, M. Takakura, M., Kyo, S., Kanaya, T., Hirano, H., Takeda, J., Yutsudo, M., and Inoue, M. (1999) Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells. Cancer Res., 59, 551-557.
    • (1999) Cancer Res. , vol.59 , pp. 551-557
    • Takakura, M.1    Kyo, S.2    Kanaya, T.3    Hirano, H.4    Takeda, J.5    Yutsudo, M.6    Inoue, M.7    Takakura, M.8    Kyo, S.9    Kanaya, T.10    Hirano, H.11    Takeda, J.12    Yutsudo, M.13    Inoue, M.14
  • 14
    • 0345549479 scopus 로고    scopus 로고
    • Regulation of telomerase reverse transcriptase gene activity by upstream stimulatory factor
    • Goueli, B.S. and Janknecht, R.Goueli, B.S. and Janknecht, R. (2003) Regulation of telomerase reverse transcriptase gene activity by upstream stimulatory factor. Oncogene, 22, 8042-8047.
    • (2003) Oncogene , vol.22 , pp. 8042-8047
    • Goueli, B.S.1    Janknecht, R.2    Goueli, B.S.3    Janknecht, R.4
  • 17
    • 53049108799 scopus 로고    scopus 로고
    • Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc
    • Xu, D., Dwyer, J., Li, H., Duan, W., and Liu, J.P.Xu, D., Dwyer, J., Li, H., Duan, W., and Liu, J.P. (2008) Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc. J. Biol. Chem., 283, 23567-23580.
    • (2008) J. Biol. Chem. , vol.283 , pp. 23567-23580
    • Xu, D.1    Dwyer, J.2    Li, H.3    Duan, W.4    Liu, J.P.5    Xu, D.6    Dwyer, J.7    Li, H.8    Duan, W.9    Liu, J.P.10
  • 18
    • 79953142510 scopus 로고    scopus 로고
    • Chromatin and epigenetic regulation of the telomerase reverse transcriptase gene
    • Zhu, J., Zhao, Y., andWang, S.Zhu, J., Zhao, Y., andWang, S. (2010) Chromatin and epigenetic regulation of the telomerase reverse transcriptase gene. Protein Cell, 1, 22-32.
    • (2010) Protein Cell , vol.1 , pp. 22-32
    • Zhu, J.1    Zhao, Y.2    Wang, S.3    Zhu, J.4    Zhao, Y.5    Wang, S.6
  • 24
    • 0038820037 scopus 로고    scopus 로고
    • Evidence for a relief of repression mechanism for activation of the human telomerase reverse transcriptase promoter
    • Wang, S. and Zhu, J.Wang, S. and Zhu, J. (2003) Evidence for a relief of repression mechanism for activation of the human telomerase reverse transcriptase promoter. J. Biol. Chem., 278, 18842-18850.
    • (2003) J. Biol. Chem. , vol.278 , pp. 18842-18850
    • Wang, S.1    Zhu, J.2    Wang, S.3    Zhu, J.4
  • 25
    • 0034680840 scopus 로고    scopus 로고
    • Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells
    • Cong, Y.S. and Bacchetti, S.Cong, Y.S. and Bacchetti, S. (2000) Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells. J. Biol. Chem., 275, 35665-35668.
    • (2000) J. Biol. Chem. , vol.275 , pp. 35665-35668
    • Cong, Y.S.1    Bacchetti, S.2    Cong, Y.S.3    Bacchetti, S.4
  • 27
    • 11244349707 scopus 로고    scopus 로고
    • The hTERT gene is embedded in a nuclease-resistant chromatin domain
    • Wang, S. and Zhu, J.Wang, S. and Zhu, J. (2004) The hTERT gene is embedded in a nuclease-resistant chromatin domain. J. Biol. Chem., 279, 55401-55410.
    • (2004) J. Biol. Chem. , vol.279 , pp. 55401-55410
    • Wang, S.1    Zhu, J.2    Wang, S.3    Zhu, J.4
  • 28
    • 0024426688 scopus 로고
    • Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen
    • Shay, J.W. and Wright, W.E.Shay, J.W. and Wright, W.E. (1989) Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen. Exp. Cell Res., 184, 109-118.
    • (1989) Exp. Cell Res. , vol.184 , pp. 109-118
    • Shay, J.W.1    Wright, W.E.2    Shay, J.W.3    Wright, W.E.4
  • 29
    • 73049101016 scopus 로고    scopus 로고
    • Studying human telomerase gene transcription by a chromatinized reporter generated by recombinase-mediated targeting of a bacterial artificial chromosome
    • Wang, S., Zhao, Y., Leiby, M.A., and Zhu, J.Wang, S., Zhao, Y., Leiby, M.A., and Zhu, J. (2009) Studying human telomerase gene transcription by a chromatinized reporter generated by recombinase-mediated targeting of a bacterial artificial chromosome. Nucleic Acids Res., 37, e111.
    • (2009) Nucleic Acids Res. , vol.37 , pp. e111
    • Wang, S.1    Zhao, Y.2    Leiby, M.A.3    Zhu, J.4    Wang, S.5    Zhao, Y.6    Leiby, M.A.7    Zhu, J.8
  • 31
  • 32
    • 33846820098 scopus 로고    scopus 로고
    • Transcriptional silencing of a novel hTERT reporter locus during in vitro differentiation of mouse embryonic stem cells
    • Wang, S., Hu, C., and Zhu, J.Wang, S., Hu, C., and Zhu, J. (2007) Transcriptional silencing of a novel hTERT reporter locus during in vitro differentiation of mouse embryonic stem cells. Mol. Biol. Cell, 18, 669-677.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 669-677
    • Wang, S.1    Hu, C.2    Zhu, J.3    Wang, S.4    Hu, C.5    Zhu, J.6
  • 33
    • 9244265488 scopus 로고    scopus 로고
    • A novel human homologue of Drosophila polycomblike gene is up-regulated in multiple cancers
    • Wang, S., Robertson, G.P., and Zhu, J.Wang, S., Robertson, G.P., and Zhu, J. (2004) A novel human homologue of Drosophila polycomblike gene is up-regulated in multiple cancers. Gene, 343, 69-78.
    • (2004) Gene , vol.343 , pp. 69-78
    • Wang, S.1    Robertson, G.P.2    Zhu, J.3    Wang, S.4    Robertson, G.P.5    Zhu, J.6
  • 35
    • 0037821661 scopus 로고    scopus 로고
    • Multiple tumor suppressor pathways negatively regulate telomerase
    • Lin, S.Y. and Elledge, S.J.Lin, S.Y. and Elledge, S.J. (2003) Multiple tumor suppressor pathways negatively regulate telomerase. Cell, 113, 881-889.
    • (2003) Cell , vol.113 , pp. 881-889
    • Lin, S.Y.1    Elledge, S.J.2    Lin, S.Y.3    Elledge, S.J.4
  • 40
    • 0036884618 scopus 로고    scopus 로고
    • Opposing regulatory roles of E2F in human telomerase reverse transcriptase (hTERT) gene expression in human tumor and normal somatic cells
    • Won, J., Yim, J., and Kim, T.K.Won, J., Yim, J., and Kim, T.K. (2002) Opposing regulatory roles of E2F in human telomerase reverse transcriptase (hTERT) gene expression in human tumor and normal somatic cells. FASEB J., 16, 1943-1945.
    • (2002) FASEB J , vol.16 , pp. 1943-1945
    • Won, J.1    Yim, J.2    Kim, T.K.3    Won, J.4    Yim, J.5    Kim, T.K.6
  • 41
    • 23844469708 scopus 로고    scopus 로고
    • Sp1/Sp3-dependent regulation of human telomerase reverse transcriptase promoter activity by the bioactive sphingolipid ceramide
    • Wooten, L.G. and Ogretmen, B.Wooten, L.G. and Ogretmen, B. (2005) Sp1/Sp3-dependent regulation of human telomerase reverse transcriptase promoter activity by the bioactive sphingolipid ceramide. J. Biol. Chem., 280, 28867-28876.
    • (2005) J. Biol. Chem. , vol.280 , pp. 28867-28876
    • Wooten, L.G.1    Ogretmen, B.2    Wooten, L.G.3    Ogretmen, B.4
  • 44
  • 45
    • 84874191269 scopus 로고    scopus 로고
    • TERT promoter mutations in familial and sporadic melanoma
    • Horn, S., Figl, A., Rachakonda, P.S., Fischer, C., Sucker, A., Gast, A., Kadel, S., Moll, I., Nagore, E., and Hemminki, K. et al.Horn, S., Figl, A., Rachakonda, P.S., Fischer, C., Sucker, A., Gast, A., Kadel, S., Moll, I., Nagore, E., and Hemminki, K. (2013) TERT promoter mutations in familial and sporadic melanoma. Science, 339, 959-961.
    • (2013) Science , vol.339 , pp. 959-961
    • Horn, S.1    Figl, A.2    Rachakonda, P.S.3    Fischer, C.4    Sucker, A.5    Gast, A.6    Kadel, S.7    Moll, I.8    Nagore, E.9    Hemminki, K.10
  • 48
    • 79952828836 scopus 로고    scopus 로고
    • Transcriptional repression: The dark side of myc
    • Herkert, B. and Eilers, M.Herkert, B. and Eilers, M. (2010) Transcriptional repression: the dark side of myc. Genes Cancer, 1, 580-586.
    • (2010) Genes Cancer , vol.1 , pp. 580-586
    • Herkert, B.1    Eilers, M.2    Herkert, B.3    Eilers, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.