메뉴 건너뛰기




Volumn 18, Issue 1, 2012, Pages

E2F1: A potential negative regulator of hTERT transcription in normal cells upon activation of oncogenic c-Myc

Author keywords

c Myc; E2F1; Feedback regulation; hTERT; miR 17 92 cluster

Indexed keywords

TELOMERASE REVERSE TRANSCRIPTASE; TRANSCRIPTION FACTOR E2F1;

EID: 84855261286     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: 10.12659/MSM.882192     Document Type: Review
Times cited : (22)

References (30)
  • 2
    • 77951640687 scopus 로고    scopus 로고
    • MYC in oncogenesis and as a target for cancer therapies
    • Albihn A, Johnsen JI, Henriksson MA: MYC in oncogenesis and as a target for cancer therapies. Adv Cancer Res, 2010; 107: 163-224
    • (2010) Adv Cancer Res , vol.107 , pp. 163-224
    • Albihn, A.1    Johnsen, J.I.2    Henriksson, M.A.3
  • 3
    • 0141996279 scopus 로고    scopus 로고
    • The c-MYC oncoprotein as a treatment target in cancer and other disorders of cell growth
    • Pelengaris S, Khan M: The c-MYC oncoprotein as a treatment target in cancer and other disorders of cell growth. Expert Opin Ther Targets, 2003; 7: 623-42
    • (2003) Expert Opin Ther Targets , vol.7 , pp. 623-642
    • Pelengaris, S.1    Khan, M.2
  • 4
    • 0025251664 scopus 로고
    • Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2
    • Strasser A, Harris AW, Bath ML, Cory S: Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2. Nature, 1990; 348: 331-33
    • (1990) Nature , vol.348 , pp. 331-333
    • Strasser, A.1    Harris, A.W.2    Bath, M.L.3    Cory, S.4
  • 5
    • 34250841785 scopus 로고    scopus 로고
    • Replication and protection of telomeres
    • Verdun RE, Karlseder J: Replication and protection of telomeres. Nature, 2007; 447: 924-31
    • (2007) Nature , vol.447 , pp. 924-931
    • Verdun, R.E.1    Karlseder, J.2
  • 6
    • 80051486536 scopus 로고    scopus 로고
    • The expression levels of stem cell markers importin13, ckit, CD146, and telomerase are decreased in endometrial polyps
    • Hu J, Yuan R: The expression levels of stem cell markers importin13, ckit, CD146, and telomerase are decreased in endometrial polyps. Med Sci Monit, 2011; 17(8): BR221-27
    • (2011) Med Sci Monit , vol.17 , Issue.8
    • Hu, J.1    Yuan, R.2
  • 7
    • 0030681073 scopus 로고    scopus 로고
    • Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types
    • Kilian A, Bowtell DD, Abud HE et al: Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types. Hum Mol Genet, 1997; 6: 2011-19
    • (1997) Hum Mol Genet , vol.6 , pp. 2011-2019
    • Kilian, A.1    Bowtell, D.D.2    Abud, H.E.3
  • 8
    • 0032485416 scopus 로고    scopus 로고
    • Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase
    • Counter CM, Meyerson M, Eaton EN et al: Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase. Oncogene, 1998; 16: 1217-22
    • (1998) Oncogene , vol.16 , pp. 1217-1222
    • Counter, C.M.1    Meyerson, M.2    Eaton, E.N.3
  • 9
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim NW, Piatyszek MA, Prowse KR et al: Specific association of human telomerase activity with immortal cells and cancer. Science, 1994; 266: 2011-15
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3
  • 10
    • 0020520516 scopus 로고
    • Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
    • Land H, Parada LF, Weinberg RA: Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature, 1983; 304: 596-602
    • (1983) Nature , vol.304 , pp. 596-602
    • Land, H.1    Parada, L.F.2    Weinberg, R.A.3
  • 11
    • 0032911694 scopus 로고    scopus 로고
    • Direct activation of TERT transcription by c-MYC
    • Wu KJ, Grandori C, Amacker M et al: Direct activation of TERT transcription by c-MYC. Nat Genet, 1999; 21: 220-24
    • (1999) Nat Genet , vol.21 , pp. 220-224
    • Wu, K.J.1    Grandori, C.2    Amacker, M.3
  • 12
    • 0742324404 scopus 로고    scopus 로고
    • Life and death decisions by E2F-1
    • Bell LA, Ryan KM: Life and death decisions by E2F-1. Cell Death Differ, 2004; 11: 137-42
    • (2004) Cell Death Differ , vol.11 , pp. 137-142
    • Bell, L.A.1    Ryan, K.M.2
  • 13
    • 70350270053 scopus 로고    scopus 로고
    • The E2F family and the role of E2F1 in apoptosis
    • Wu Z, Zheng S, Yu Q: The E2F family and the role of E2F1 in apoptosis. Int J Biochem Cell Biol, 2009; 41: 2389-97
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 2389-2397
    • Wu, Z.1    Zheng, S.2    Yu, Q.3
  • 14
    • 0035394055 scopus 로고    scopus 로고
    • E2F-1 represses transcription of the human telomerase reverse transcriptase gene
    • Crowe DL, Nguyen DC, Tsang KJ, Kyo S: E2F-1 represses transcription of the human telomerase reverse transcriptase gene. Nucleic Acids Res, 2001; 29: 2789-94
    • (2001) Nucleic Acids Res , vol.29 , pp. 2789-2794
    • Crowe, D.L.1    Nguyen, D.C.2    Tsang, K.J.3    Kyo, S.4
  • 15
    • 36248978188 scopus 로고    scopus 로고
    • Transforming growth factor-beta inhibits telomerase through SMAD3 and E2F transcription factors
    • Lacerte A, Korah J, Roy M et al: Transforming growth factor-beta inhibits telomerase through SMAD3 and E2F transcription factors. Cell Signal, 2008; 20: 50-59
    • (2008) Cell Signal , vol.20 , pp. 50-59
    • Lacerte, A.1    Korah, J.2    Roy, M.3
  • 16
    • 42649083023 scopus 로고    scopus 로고
    • Transduction of E2F-1 TAT fusion proteins represses expression of hTERT in primary ductal breast carcinoma cell lines
    • Elliott KA, Rickords LF, Labrum JM: Transduction of E2F-1 TAT fusion proteins represses expression of hTERT in primary ductal breast carcinoma cell lines. Mol Cancer, 2008; 7: 28
    • (2008) Mol Cancer , vol.7 , pp. 28
    • Elliott, K.A.1    Rickords, L.F.2    Labrum, J.M.3
  • 17
    • 0742281300 scopus 로고    scopus 로고
    • E2F1 and c-Myc in cell growth and death
    • Matsumura I, Tanaka H, Kanakura Y: E2F1 and c-Myc in cell growth and death. Cell Cycle, 2003; 2: 333-38
    • (2003) Cell Cycle , vol.2 , pp. 333-338
    • Matsumura, I.1    Tanaka, H.2    Kanakura, Y.3
  • 18
    • 0030995824 scopus 로고    scopus 로고
    • Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
    • Leone G, DeGregori J, Sears R et al: Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature, 1997; 387: 422-26
    • (1997) Nature , vol.387 , pp. 422-426
    • Leone, G.1    Degregori, J.2    Sears, R.3
  • 19
    • 0038185378 scopus 로고    scopus 로고
    • Genomic targets of the human c-Myc protein
    • Fernandez PC, Frank SR, Wang L et al: Genomic targets of the human c-Myc protein. Genes Dev, 2003; 17: 1115-29
    • (2003) Genes Dev , vol.17 , pp. 1115-1129
    • Fernandez, P.C.1    Frank, S.R.2    Wang, L.3
  • 20
    • 34548381748 scopus 로고    scopus 로고
    • Myc'ed messages: Myc induces transcription of E2F1 while inhibiting its translation via a microRNA polycistron
    • Coller HA, Forman JJ, Legesse-Miller A: "Myc'ed messages": myc induces transcription of E2F1 while inhibiting its translation via a microRNA polycistron. PLoS Genet, 2007; 3: e146
    • (2007) PLoS Genet , vol.e146 , pp. 3
    • Coller, H.A.1    Forman, J.J.2
  • 21
    • 20444479428 scopus 로고    scopus 로고
    • C-Myc-regulated microRNAs modulate E2F1 expression
    • O'Donnell KA, Wentzel EA, Zeller KI et al: c-Myc-regulated microRNAs modulate E2F1 expression. Nature, 2005; 435: 839-43
    • (2005) Nature , vol.435 , pp. 839-843
    • O'Donnell, K.A.1    Wentzel, E.A.2    Zeller, K.I.3
  • 22
    • 34047267329 scopus 로고    scopus 로고
    • An E2F/miR-20a autoregulatory feedback loop
    • Sylvestre Y, De Guire V, Querido E et al: An E2F/miR-20a autoregulatory feedback loop. J Biol Chem, 2007; 282: 2135-43
    • (2007) J Biol Chem , vol.282 , pp. 2135-2143
    • Sylvestre, Y.1    de Guire, V.2    Querido, E.3
  • 23
    • 58149382580 scopus 로고    scopus 로고
    • MicroRNA regulation of a cancer network: Consequences of the feedback loops involving miR-17-92, E2F, and Myc
    • Aguda BD, Kim Y, Piper-Hunter MG et al: MicroRNA regulation of a cancer network: consequences of the feedback loops involving miR-17-92, E2F, and Myc. Proc Natl Acad Sci USA, 2008; 105: 19678-83
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19678-19683
    • Aguda, B.D.1    Kim, Y.2    Piper-Hunter, M.G.3
  • 24
    • 0036606643 scopus 로고    scopus 로고
    • Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model
    • Rounbehler RJ, Rogers PM, Conti CJ, Johnson DG: Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model. Cancer Res, 2002; 62: 3276-81
    • (2002) Cancer Res , vol.62 , pp. 3276-3281
    • Rounbehler, R.J.1    Rogers, P.M.2    Conti, C.J.3    Johnson, D.G.4
  • 25
    • 0038298900 scopus 로고    scopus 로고
    • Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss
    • Baudino TA, Maclean KH, Brennan J et al: Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss. Mol Cell, 2003; 11: 905-14
    • (2003) Mol Cell , vol.11 , pp. 905-914
    • Baudino, T.A.1    Maclean, K.H.2    Brennan, J.3
  • 26
    • 0037470449 scopus 로고    scopus 로고
    • E2F1 blocks and c-Myc accelerates hepatic ploidy in transgenic mouse models
    • Conner EA, Lemmer ER, Sánchez A et al: E2F1 blocks and c-Myc accelerates hepatic ploidy in transgenic mouse models. Biochem Biophys Res Commun, 2003; 302: 114-20
    • (2003) Biochem Biophys Res Commun , vol.302 , pp. 114-120
    • Conner, E.A.1    Lemmer, E.R.2    Sánchez, A.3
  • 27
    • 0842278571 scopus 로고    scopus 로고
    • An integrated database of genes responsive to the Myc oncogenic transcription factor: Identification of direct genomic targets
    • Zeller KI, Jegga AG, Aronow BJ et al: An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets. Genome Biol, 2003; 4: R69
    • (2003) Genome Biol , vol.4
    • Zeller, K.I.1    Jegga, A.G.2    Aronow, B.J.3
  • 28
    • 49749139661 scopus 로고    scopus 로고
    • Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers
    • Kyo S, Takakura M, Fujiwara T, Inoue M: Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers. Cancer Sci, 2008; 99: 1528-38
    • (2008) Cancer Sci , vol.99 , pp. 1528-1538
    • Kyo, S.1    Takakura, M.2    Fujiwara, T.3    Inoue, M.4
  • 29
    • 54049120956 scopus 로고    scopus 로고
    • E2F at the crossroads of life and death
    • Polager S, Ginsberg D: E2F at the crossroads of life and death. Trends Cell Biol, 2008; 18: 528-35
    • (2008) Trends Cell Biol , vol.18 , pp. 528-535
    • Polager, S.1    Ginsberg, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.