Human telomerase reverse transcriptase (hTERT) transcription requires Sp1/Sp3 binding to the promoter and a permissive chromatin environment

Journal of Biological Chemistry

Volumn 290, Issue 50, 2015, Pages 30193-30203

  Cheng, De ^a   Zhao, Yuanjun ^b   Wang, Shuwen ^a   Jia, Wenwen ^c   Kang, Jiuhong ^c   Zhu, Jiyue ^a,b  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c TONGJI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; BINS; CHROMOSOMES; PROTEINS;

BACTERIAL ARTIFICIAL CHROMOSOMES; BINDING PROTEINS; CHROMATIN ENVIRONMENT; CHROMOSOMAL INTEGRATION; HISTONE ACETYLATION; HUMAN TELOMERASE REVERSE TRANSCRIPTASE (HTERT); PROMOTER ACTIVITIES; TRANSCRIPTIONAL ACTIVITY;

TRANSCRIPTION;

BINDING PROTEIN; E BOX BINDING PROTEIN; HISTONE H3; TELOMERASE REVERSE TRANSCRIPTASE; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; UNCLASSIFIED DRUG; CHROMATIN; PROTEIN BINDING; TELOMERASE; TERT PROTEIN, HUMAN;

ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CHROMATIN; CONTROLLED STUDY; ENZYME REGULATION; GENE SEQUENCE; GENE SILENCING; GENETIC REGULATION; GENETIC TRANSCRIPTION; GENOME; HISTONE ACETYLATION; HISTONE METHYLATION; HTERT GENE; HUMAN; HUMAN CELL; MUTATION; PERMISSIVE CHROMATIN ENVIRONMENT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; CELL LINE; GENETICS; METABOLISM;

CELL LINE; CHROMATIN; HUMANS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; SP1 TRANSCRIPTION FACTOR; SP3 TRANSCRIPTION FACTOR; TELOMERASE; TRANSCRIPTION, GENETIC;

EID: 84949640899     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.662221     Document Type: Article

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