-
1
-
-
0033534510
-
Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription
-
Agarwal S.K., Guru S.C., Heppner C., Erdos M.R., Collins R.M., Park S.Y., Saggar S., Chandrasekharappa S.C., Collins F.S., Spiegel A.M.et al. Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription. Cell. 96:1999;143-152.
-
(1999)
Cell
, vol.96
, pp. 143-152
-
-
Agarwal, S.K.1
Guru, S.C.2
Heppner, C.3
Erdos, M.R.4
Collins, R.M.5
Park, S.Y.6
Saggar, S.7
Chandrasekharappa, S.C.8
Collins, F.S.9
Spiegel, A.M.10
-
3
-
-
0033835452
-
Mice without telomerase: What can they teach us about human cancer?
-
Artandi S.E., DePinho R.A. Mice without telomerase. what can they teach us about human cancer? Nat. Med. 6:2000;852-855.
-
(2000)
Nat. Med.
, vol.6
, pp. 852-855
-
-
Artandi, S.E.1
DePinho, R.A.2
-
4
-
-
0029814513
-
Mad proteins contain a dominant transcription repression domain
-
Ayer D.E., Laherty C.D., Lawrence Q.A., Armstrong A.P., Eisenman R.N. Mad proteins contain a dominant transcription repression domain. Mol. Cell. Biol. 16:1996;5772-5781.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5772-5781
-
-
Ayer, D.E.1
Laherty, C.D.2
Lawrence, Q.A.3
Armstrong, A.P.4
Eisenman, R.N.5
-
5
-
-
0036849595
-
Mouse models to study the role of telomeres in cancer, aging and DNA repair
-
Blasco M.A. Mouse models to study the role of telomeres in cancer, aging and DNA repair. Eur. J. Cancer. 38:2002;2222-2228.
-
(2002)
Eur. J. Cancer
, vol.38
, pp. 2222-2228
-
-
Blasco, M.A.1
-
6
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco M.A., Lee H.W., Hande M.P., Samper E., Lansdorp P.M., DePinho R.A., Greider C.W. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell. 91:1997;25-34.
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.W.2
Hande, M.P.3
Samper, E.4
Lansdorp, P.M.5
DePinho, R.A.6
Greider, C.W.7
-
7
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp T.R., Bernards R., Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science. 296:2002;550-553.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
8
-
-
0030697342
-
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor derived cell lines
-
Bryan T.M., Englezou A., Dalla-Pozza L., Dunham M.A., Reddel R.R. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor derived cell lines. Nat. Med. 3:1997;1271-1274.
-
(1997)
Nat. Med.
, vol.3
, pp. 1271-1274
-
-
Bryan, T.M.1
Englezou, A.2
Dalla-Pozza, L.3
Dunham, M.A.4
Reddel, R.R.5
-
9
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
Bunz F., Hwang P.M., Torrance C., Waldman T., Zhang Y., Dillehay L., Williams J., Lengauer C., Kinzler K.W., Vogelstein B. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J. Clin. Invest. 104:1999;263-269.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 263-269
-
-
Bunz, F.1
Hwang, P.M.2
Torrance, C.3
Waldman, T.4
Zhang, Y.5
Dillehay, L.6
Williams, J.7
Lengauer, C.8
Kinzler, K.W.9
Vogelstein, B.10
-
10
-
-
0037308404
-
Association between telomere length in blood and mortality in people aged 60 years or older
-
Cawthon R.M., Smith K.R., O'Brien E., Sivatchenko A., Kerber R.A. Association between telomere length in blood and mortality in people aged 60 years or older. Lancet. 361:2003;393-395.
-
(2003)
Lancet
, vol.361
, pp. 393-395
-
-
Cawthon, R.M.1
Smith, K.R.2
O'Brien, E.3
Sivatchenko, A.4
Kerber, R.A.5
-
11
-
-
0034964418
-
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion
-
Comijn J., Berx G., Vermassen P., Verschueren K., van Grunsven L., Bruyneel E., Mareel M., Huylebroeck D., van Roy F. The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol. Cell. 7:2001;1267-1278.
-
(2001)
Mol. Cell
, vol.7
, pp. 1267-1278
-
-
Comijn, J.1
Berx, G.2
Vermassen, P.3
Verschueren, K.4
Van Grunsven, L.5
Bruyneel, E.6
Mareel, M.7
Huylebroeck, D.8
Van Roy, F.9
-
13
-
-
0026523228
-
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
-
Counter C.M., Avilion A.A., LeFeuvre C.E., Stewart N.G., Greider C.W., Harley C.B., Bacchetti S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11:1992;1921-1929.
-
(1992)
EMBO J.
, vol.11
, pp. 1921-1929
-
-
Counter, C.M.1
Avilion, A.A.2
LeFeuvre, C.E.3
Stewart, N.G.4
Greider, C.W.5
Harley, C.B.6
Bacchetti, S.7
-
14
-
-
0032440891
-
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization
-
Counter C.M., Hahn W.C., Wei W., Caddle S.D., Beijersbergen R.L., Lansdorp P.M., Sedivy J.M., Weinberg R.A. Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Proc. Natl. Acad. Sci. USA. 95:1998;14723-14728.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14723-14728
-
-
Counter, C.M.1
Hahn, W.C.2
Wei, W.3
Caddle, S.D.4
Beijersbergen, R.L.5
Lansdorp, P.M.6
Sedivy, J.M.7
Weinberg, R.A.8
-
15
-
-
0029126004
-
The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb
-
Craven R.J., Cance W.G., Liu E.T. The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb. Cancer Res. 55:1995;3969-3972.
-
(1995)
Cancer Res.
, vol.55
, pp. 3969-3972
-
-
Craven, R.J.1
Cance, W.G.2
Liu, E.T.3
-
16
-
-
0028201293
-
Activation of telomerase in a human tumor
-
de Lange T. Activation of telomerase in a human tumor. Proc. Natl. Acad. Sci. USA. 91:1994;2882-2885.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2882-2885
-
-
De Lange, T.1
-
17
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri G.P., Lee X., Basile G., Acosta M., Scott G., Roskelley C., Medrano E.E., Linskens M., Rubelj I., Pereira-Smith O.et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. USA. 92:1995;9363-9367.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
-
18
-
-
0037148401
-
Regulation of the human telomerase reverse transcriptase gene
-
Ducrest A.L., Szutorisz H., Lingner J., Nabholz M. Regulation of the human telomerase reverse transcriptase gene. Oncogene. 21:2002;541-552.
-
(2002)
Oncogene
, vol.21
, pp. 541-552
-
-
Ducrest, A.L.1
Szutorisz, H.2
Lingner, J.3
Nabholz, M.4
-
19
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir S.M., Harborth J., Lendeckel W., Yalcin A., Weber K., Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 411:2001;494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
20
-
-
0036362266
-
Telomerase and differentiation in multicellular organisms: Turn it off, turn it on, and turn it off again
-
Forsyth N.R., Wright W.E., Shay J.W. Telomerase and differentiation in multicellular organisms. turn it off, turn it on, and turn it off again Differentiation. 69:2002;188-197.
-
(2002)
Differentiation
, vol.69
, pp. 188-197
-
-
Forsyth, N.R.1
Wright, W.E.2
Shay, J.W.3
-
21
-
-
0029894237
-
Telomere length regulation
-
Greider C.W. Telomere length regulation. Annu. Rev. Biochem. 65:1996;337-365.
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 337-365
-
-
Greider, C.W.1
-
22
-
-
0031939872
-
Telomerase activity, cell proliferation, and cancer
-
Greider C.W. Telomerase activity, cell proliferation, and cancer. Proc. Natl. Acad. Sci. USA. 95:1998;90-92.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 90-92
-
-
Greider, C.W.1
-
23
-
-
0023663881
-
The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
-
Greider C.W., Blackburn E.H. The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell. 51:1987;887-898.
-
(1987)
Cell
, vol.51
, pp. 887-898
-
-
Greider, C.W.1
Blackburn, E.H.2
-
24
-
-
0030060521
-
Telomeres, telomerase and cancer
-
Greider C.W., Blackburn E.H. Telomeres, telomerase and cancer. Sci. Am. 274:1996;92-97.
-
(1996)
Sci. Am.
, vol.274
, pp. 92-97
-
-
Greider, C.W.1
Blackburn, E.H.2
-
25
-
-
0034626747
-
Genetic pathways that regulate ageing in model organisms
-
Guarente L., Kenyon C. Genetic pathways that regulate ageing in model organisms. Nature. 408:2000;255-262.
-
(2000)
Nature
, vol.408
, pp. 255-262
-
-
Guarente, L.1
Kenyon, C.2
-
26
-
-
0035045477
-
Telomerase activation, cellular immortalization and cancer
-
Hahn W.C., Meyerson M. Telomerase activation, cellular immortalization and cancer. Ann. Med. 33:2001;123-129.
-
(2001)
Ann. Med.
, vol.33
, pp. 123-129
-
-
Hahn, W.C.1
Meyerson, M.2
-
27
-
-
0033614998
-
Creation of human tumor cells with defined genetic elements
-
Hahn W.C., Counter C.M., Lundberg A.S., Beijersbergen R.L., Brooks M.W., Weinberg R.A. Creation of human tumor cells with defined genetic elements. Nature. 400:1999;464-468.
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
Beijersbergen, R.L.4
Brooks, M.W.5
Weinberg, R.A.6
-
28
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell. 100:2000;57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
29
-
-
17944367982
-
The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation
-
Heppner C., Bilimoria K.Y., Agarwal S.K., Kester M., Whitty L.J., Guru S.C., Chandrasekharappa S.C., Collins F.S., Spiegel A.M., Marx S.J., Burns A.L. The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation. Oncogene. 20:2001;4917-4925.
-
(2001)
Oncogene
, vol.20
, pp. 4917-4925
-
-
Heppner, C.1
Bilimoria, K.Y.2
Agarwal, S.K.3
Kester, M.4
Whitty, L.J.5
Guru, S.C.6
Chandrasekharappa, S.C.7
Collins, F.S.8
Spiegel, A.M.9
Marx, S.J.10
Burns, A.L.11
-
30
-
-
0032923742
-
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype
-
Jiang X.R., Jimenez G., Chang E., Frolkis M., Kusler B., Sage M., Beeche M., Bodnar A.G., Wahl G.M., Tlsty T.D., Chiu C.P. Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nat. Genet. 21:1999;111-114.
-
(1999)
Nat. Genet.
, vol.21
, pp. 111-114
-
-
Jiang, X.R.1
Jimenez, G.2
Chang, E.3
Frolkis, M.4
Kusler, B.5
Sage, M.6
Beeche, M.7
Bodnar, A.G.8
Wahl, G.M.9
Tlsty, T.D.10
Chiu, C.P.11
-
31
-
-
0034048726
-
Adenoviral expression of p53 represses telomerase activity through down-regulation of human telomerase reverse transcriptase transcription
-
Kanaya T., Kyo S., Hamada K., Takakura M., Kitagawa Y., Harada H., Inoue M. Adenoviral expression of p53 represses telomerase activity through down-regulation of human telomerase reverse transcriptase transcription. Clin. Cancer Res. 6:2000;1239-1247.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1239-1247
-
-
Kanaya, T.1
Kyo, S.2
Hamada, K.3
Takakura, M.4
Kitagawa, Y.5
Harada, H.6
Inoue, M.7
-
32
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim N.W., Piatyszek M.A., Prowse K.R., Harley C.B., West M.D., Ho P.L., Coviello G.M., Wright W.E., Weinrich S.L., Shay J.W. Specific association of human telomerase activity with immortal cells and cancer. Science. 266:1994;2011-2015.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
33
-
-
0037148327
-
Complex regulatory mechanisms of telomerase activity in normal and cancer cells: How can we apply them for cancer therapy?
-
Kyo S., Inoue M. Complex regulatory mechanisms of telomerase activity in normal and cancer cells. how can we apply them for cancer therapy? Oncogene. 21:2002;688-697.
-
(2002)
Oncogene
, vol.21
, pp. 688-697
-
-
Kyo, S.1
Inoue, M.2
-
34
-
-
0032499210
-
Essential role of mouse telomerase in highly proliferative organs
-
Lee H.W., Blasco M.A., Gottlieb G.J., Horner J.W. 2nd, Greider C.W., DePinho R.A. Essential role of mouse telomerase in highly proliferative organs. Nature. 392:1998;569-574.
-
(1998)
Nature
, vol.392
, pp. 569-574
-
-
Lee, H.W.1
Blasco, M.A.2
Gottlieb, G.J.3
Horner II, J.W.4
Greider, C.W.5
DePinho, R.A.6
-
35
-
-
0034619761
-
Genetic screens in mammalian cells by enhanced retroviral mutagens
-
Liu D., Yang X., Yang D., Songyang Z. Genetic screens in mammalian cells by enhanced retroviral mutagens. Oncogene. 19:2000;5964-5972.
-
(2000)
Oncogene
, vol.19
, pp. 5964-5972
-
-
Liu, D.1
Yang, X.2
Yang, D.3
Songyang, Z.4
-
36
-
-
0019723823
-
Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences
-
Lusky M., Botchan M. Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences. Nature. 293:1981;79-81.
-
(1981)
Nature
, vol.293
, pp. 79-81
-
-
Lusky, M.1
Botchan, M.2
-
37
-
-
0037323195
-
Stem cells, telomerase and dyskeratosis congenita
-
Mason P.J. Stem cells, telomerase and dyskeratosis congenita. Bioessays. 25:2003;126-133.
-
(2003)
Bioessays
, vol.25
, pp. 126-133
-
-
Mason, P.J.1
-
38
-
-
0032531169
-
Multiple endocrine neoplasia type 1: Clinical and genetic topics
-
Marx S., Spiegel A.M., Skarulis M.C., Doppman J.L., Collins F.S., Liotta L.A. Multiple endocrine neoplasia type 1. clinical and genetic topics Ann. Intern. Med. 129:1998;484-494.
-
(1998)
Ann. Intern. Med.
, vol.129
, pp. 484-494
-
-
Marx, S.1
Spiegel, A.M.2
Skarulis, M.C.3
Doppman, J.L.4
Collins, F.S.5
Liotta, L.A.6
-
40
-
-
0030745448
-
HEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
-
Meyerson M., Counter C.M., Eaton E.N., Ellisen L.W., Steiner P., Caddle S.D., Ziaugra L., Beijersbergen R.L., Davidoff M.J., Liu Q.et al. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell. 90:1997;785-795.
-
(1997)
Cell
, vol.90
, pp. 785-795
-
-
Meyerson, M.1
Counter, C.M.2
Eaton, E.N.3
Ellisen, L.W.4
Steiner, P.5
Caddle, S.D.6
Ziaugra, L.7
Beijersbergen, R.L.8
Davidoff, M.J.9
Liu, Q.10
-
41
-
-
0035032219
-
Hypoxia extends the life span of vascular smooth muscle cells through telomerase activation
-
Minamino T., Mitsialis S.A., Kourembanas S. Hypoxia extends the life span of vascular smooth muscle cells through telomerase activation. Mol. Cell. Biol. 21:2001;3336-3342.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3336-3342
-
-
Minamino, T.1
Mitsialis, S.A.2
Kourembanas, S.3
-
42
-
-
0032924343
-
Absence of cancer-associated changes in human fibroblasts immortalized with telomerase
-
Morales C.P., Holt S.E., Ouellette M., Kaur K.J., Yan Y., Wilson K.S., White M.A., Wright W.E., Shay J.W. Absence of cancer-associated changes in human fibroblasts immortalized with telomerase. Nat. Genet. 1:1999;115-118.
-
(1999)
Nat. Genet.
, vol.1
, pp. 115-118
-
-
Morales, C.P.1
Holt, S.E.2
Ouellette, M.3
Kaur, K.J.4
Yan, Y.5
Wilson, K.S.6
White, M.A.7
Wright, W.E.8
Shay, J.W.9
-
43
-
-
0030819894
-
Telomerase catalytic subunit homologs from fission yeast and human
-
Nakamura T.M., Morin G.B., Chapman K.B., Weinrich S.L., Andrews W.H., Lingner J., Harley C.B., Cech T.R. Telomerase catalytic subunit homologs from fission yeast and human. Science. 277:1997;955-959.
-
(1997)
Science
, vol.277
, pp. 955-959
-
-
Nakamura, T.M.1
Morin, G.B.2
Chapman, K.B.3
Weinrich, S.L.4
Andrews, W.H.5
Lingner, J.6
Harley, C.B.7
Cech, T.R.8
-
44
-
-
0034624675
-
Identification of Mad as a repressor of the human telomerase (hTERT) gene
-
Oh S., Song Y.-H., Yim J., Kim T.K. Identification of Mad as a repressor of the human telomerase (hTERT) gene. Oncogene. 19:2000;1485-1490.
-
(2000)
Oncogene
, vol.19
, pp. 1485-1490
-
-
Oh, S.1
Song, Y.-H.2
Yim, J.3
Kim, T.K.4
-
45
-
-
0030979581
-
Multiple pathways to cellular senescence: Role of telomerase repressors
-
Oshimura M., Barrett J.C. Multiple pathways to cellular senescence. role of telomerase repressors Eur. J. Cancer. 33:1997;710-715.
-
(1997)
Eur. J. Cancer
, vol.33
, pp. 710-715
-
-
Oshimura, M.1
Barrett, J.C.2
-
46
-
-
0034616215
-
Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase
-
Ouellette M., Liao M., Herbert B.S., Johnson M., Holt S.E., Liss H.S., Shay J.W., Wright W.E. Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase. J. Biol. Chem. 275:2000;10072-10076.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10072-10076
-
-
Ouellette, M.1
Liao, M.2
Herbert, B.S.3
Johnson, M.4
Holt, S.E.5
Liss, H.S.6
Shay, J.W.7
Wright, W.E.8
-
47
-
-
0027275469
-
Downstream signal transduction defects that suppress transformation in two revertant cell lines expressing activated rat neu oncogene
-
Reardon D.B., Hung M.-C. Downstream signal transduction defects that suppress transformation in two revertant cell lines expressing activated rat neu oncogene. J. Biol. Chem. 268:1993;18136-18142.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 18136-18142
-
-
Reardon, D.B.1
Hung, M.-C.2
-
48
-
-
0033525558
-
Longevity, stress response, and cancer in aging telomerase-deficient mice
-
Rudolph K.L., Chang S., Lee H.W., Blasco M., Gottlieb G.J., Greider C., DePinho R.A. Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell. 96:1999;701-712.
-
(1999)
Cell
, vol.96
, pp. 701-712
-
-
Rudolph, K.L.1
Chang, S.2
Lee, H.W.3
Blasco, M.4
Gottlieb, G.J.5
Greider, C.6
DePinho, R.A.7
-
49
-
-
0035437179
-
Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential
-
Rufer N., Migliaccio M., Antonchuk J., Humphries R.K., Roosnek E., Lansdorp P.M. Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential. Blood. 98:2001;597-603.
-
(2001)
Blood
, vol.98
, pp. 597-603
-
-
Rufer, N.1
Migliaccio, M.2
Antonchuk, J.3
Humphries, R.K.4
Roosnek, E.5
Lansdorp, P.M.6
-
50
-
-
0031010342
-
A survey of telomerase activity in human cancer
-
Shay J.W., Bacchetti S. A survey of telomerase activity in human cancer. Eur. J. Cancer. 33:1997;787-791.
-
(1997)
Eur. J. Cancer
, vol.33
, pp. 787-791
-
-
Shay, J.W.1
Bacchetti, S.2
-
51
-
-
0035984714
-
Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells
-
Simonsen J.L., Rosada C., Serakinci N., Justesen J., Stenderup K., Rattan S.I., Jensen T.G., Kassem M. Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells. Nat. Biotechnol. 20:2002;592-596.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 592-596
-
-
Simonsen, J.L.1
Rosada, C.2
Serakinci, N.3
Justesen, J.4
Stenderup, K.5
Rattan, S.I.6
Jensen, T.G.7
Kassem, M.8
-
52
-
-
85047686713
-
P53 Null Mutations are Associated with a Telomerase Negative Phenotype in Ovarian Carcinoma
-
Sood A.K., Coffin J., Jabbari S., Buller R.E., Hendrix M.J., Klingelhutz A. p53 Null Mutations are Associated with a Telomerase Negative Phenotype in Ovarian Carcinoma. Cancer Biol. Ther. 1:2002;511-517.
-
(2002)
Cancer Biol. Ther.
, vol.1
, pp. 511-517
-
-
Sood, A.K.1
Coffin, J.2
Jabbari, S.3
Buller, R.E.4
Hendrix, M.J.5
Klingelhutz, A.6
-
53
-
-
0035836727
-
Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells
-
Stampfer M.R., Garbe J., Levine G., Lichtsteiner S., Vasserot A.P., Yaswen P. Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells. Proc. Natl. Acad. Sci. USA. 98:2001;4498-4503.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4498-4503
-
-
Stampfer, M.R.1
Garbe, J.2
Levine, G.3
Lichtsteiner, S.4
Vasserot, A.P.5
Yaswen, P.6
-
55
-
-
0037148276
-
Senescence: Does it all happen at the ends?
-
Stewart S.A., Weinberg R.A. Senescence. does it all happen at the ends? Oncogene. 21:2002;627-630.
-
(2002)
Oncogene
, vol.21
, pp. 627-630
-
-
Stewart, S.A.1
Weinberg, R.A.2
-
56
-
-
0037382414
-
Erosion of the telomeric single-strand overhang at replicative senescence
-
Stewart S.A., Ben-Porath I., Carey V.J., O'Connor B.F., Hahn W.C., Weinberg R.A. Erosion of the telomeric single-strand overhang at replicative senescence. Nat. Genet. 33:2003;492-496.
-
(2003)
Nat. Genet.
, vol.33
, pp. 492-496
-
-
Stewart, S.A.1
Ben-Porath, I.2
Carey, V.J.3
O'Connor, B.F.4
Hahn, W.C.5
Weinberg, R.A.6
-
57
-
-
0033082526
-
Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells
-
Takakura M., Kyo S., Kanaya T., Hirano H., Takeda J., Yutsudo M., Inoue M. Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells. Cancer Res. 59:1999;551-557.
-
(1999)
Cancer Res.
, vol.59
, pp. 551-557
-
-
Takakura, M.1
Kyo, S.2
Kanaya, T.3
Hirano, H.4
Takeda, J.5
Yutsudo, M.6
Inoue, M.7
-
58
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum H.A., Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature. 410:2001;154-155.
-
(2001)
Nature
, vol.410
, pp. 154-155
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
59
-
-
0035913903
-
SIRT1 functions as an NAD-dependent p53 deacetylase
-
SIRT1 functions as an NAD-dependent p53 deacetylase. Cell. 107:2001;149-159.
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
60
-
-
0035960043
-
The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita
-
Vulliamy T., Marrone A., Goldman F., Dearlove A., Bessler M., Mason P.J., Dokal I. The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita. Nature. 413:2001;432-435.
-
(2001)
Nature
, vol.413
, pp. 432-435
-
-
Vulliamy, T.1
Marrone, A.2
Goldman, F.3
Dearlove, A.4
Bessler, M.5
Mason, P.J.6
Dokal, I.7
-
61
-
-
2642610318
-
Myc activates telomerase
-
Wang J., Xie L.Y., Allan S., Beach D., Hannon G.J. Myc activates telomerase. Genes Dev. 12:1998;1769-1774.
-
(1998)
Genes Dev.
, vol.12
, pp. 1769-1774
-
-
Wang, J.1
Xie, L.Y.2
Allan, S.3
Beach, D.4
Hannon, G.J.5
-
62
-
-
0037421896
-
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates aging
-
Wong K.K., Maser R.S., Bachoo R.M., Menon J., Carrasco D.R., Gu Y., Alt F.W., DePinho R.A. Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates aging. Nature. 421:2003;643-648.
-
(2003)
Nature
, vol.421
, pp. 643-648
-
-
Wong, K.K.1
Maser, R.S.2
Bachoo, R.M.3
Menon, J.4
Carrasco, D.R.5
Gu, Y.6
Alt, F.W.7
DePinho, R.A.8
-
63
-
-
0024366596
-
Reversible cellular senescence: Implications for immortalization of normal human diploid fibroblasts
-
Wright W.E., Pereira-Smith O.M., Shay J.W. Reversible cellular senescence. implications for immortalization of normal human diploid fibroblasts Mol. Cell. Biol. 9:1989;3088-3092.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 3088-3092
-
-
Wright, W.E.1
Pereira-Smith, O.M.2
Shay, J.W.3
-
64
-
-
0034718769
-
Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells
-
Xu D., Wang Q., Gruber A., Bjorkholm M., Chen Z., Zaid A., Selivanova G., Peterson C., Wiman K.G., Pisa P. Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells. Oncogene. 19:2000;5123-5133.
-
(2000)
Oncogene
, vol.19
, pp. 5123-5133
-
-
Xu, D.1
Wang, Q.2
Gruber, A.3
Bjorkholm, M.4
Chen, Z.5
Zaid, A.6
Selivanova, G.7
Peterson, C.8
Wiman, K.G.9
Pisa, P.10
-
65
-
-
0035957406
-
Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiationof HL60 cells
-
Xu D., Popov N., Hou M., Wang Q., Bjorkholm M., Gruber A., Menkel A.R., Henriksson M. Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiationof HL60 cells. Proc. Natl. Acad. Sci. USA. 98:2001;3826-3831.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3826-3831
-
-
Xu, D.1
Popov, N.2
Hou, M.3
Wang, Q.4
Bjorkholm, M.5
Gruber, A.6
Menkel, A.R.7
Henriksson, M.8
-
66
-
-
0035126895
-
Autocrine transforming growth factor beta suppresses telomerase activity and transcription of human telomerase reverse transcriptase in human cancer cells
-
Yang H., Kyo S., Takatura M., Sun L. Autocrine transforming growth factor beta suppresses telomerase activity and transcription of human telomerase reverse transcriptase in human cancer cells. Cell Growth Differ. 12:2001;119-127.
-
(2001)
Cell Growth Differ.
, vol.12
, pp. 119-127
-
-
Yang, H.1
Kyo, S.2
Takatura, M.3
Sun, L.4
-
67
-
-
0033616762
-
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
-
Zhu J., Wang H., Bishop J.M., Blackburn E.H. Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening. Proc. Natl. Acad. Sci. USA. 96:1999;3723-3728.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3723-3728
-
-
Zhu, J.1
Wang, H.2
Bishop, J.M.3
Blackburn, E.H.4
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