A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis

FASEB Journal

Volumn 25, Issue 3, 2011, Pages 979-989

  Jia, Wenwen ^a,b   Wang, Shuwen ^b   Horner, James W ^c   Wang, Ning ^b   Wang, Huayan ^a   Gunther, Edward J ^d   De Pinho, Ronald A ^c   Zhu, Jiyue ^b  

^a NORTHWEST A F UNIVERSITY   (China)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d PENN STATE CANCER INSTITUTE   (United States)

Author keywords

Bioluminescent imaging; hTERT gene; Mammary tumor; Transgenic mouse

Indexed keywords

MESSENGER RNA; RENILLA LUCIFERIN 2 MONOOXYGENASE; TELOMERASE REVERSE TRANSCRIPTASE; WNT1 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BREAST TUMOR; CARCINOGENESIS; CHROMOSOME POSITIONING; EMBRYO DEVELOPMENT; GENE CONTROL; GENE LOCUS; GENE SEQUENCE; GENE SILENCING; MOUSE; NONHUMAN; OVARY; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEMINIFEROUS TUBULE; SPERMATID; TESTIS; THYMUS;

AGE FACTORS; ANIMALS; CHROMOSOMES, ARTIFICIAL, BACTERIAL; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, REPORTER; GENETIC COMPLEMENTATION TEST; HUMANS; LUCIFERASES; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, TRANSGENIC; TELOMERASE; WNT1 PROTEIN;

BACTERIA (MICROORGANISMS); MUS; MUS MUSCULUS; RENILLA LUCIFERASE;

EID: 79954571660     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-173989     Document Type: Article

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