Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease

Pigment Cell and Melanoma Research

Volumn 26, Issue 2, 2013, Pages 205-217

  Dooley, Christopher M ^a   Schwarz, Heinz ^a   Mueller, Kaspar P ^b   Mongera, Alessandro ^a   Konantz, Martina ^a,c   Neuhauss, Stephan C F ^b   Nüsslein Volhard, Christiane ^a   Geisler, Robert ^a,d  

^a MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

Albinism; Melanocyte; Melanosome; Retinal pigment epithelium; Skin color variation; Slc45a2; V ATPase

Indexed keywords

ADENOSINE TRIPHOSPHATASE; MELANIN; MEMBRANE PROTEIN; SLC45A2 PROTEIN; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ULTRASTRUCTURE; CLONING; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; GENETIC CODE; HOMEOSTASIS; MELANOSOME; NONHUMAN; PH; PROTEIN INTERACTION; SKIN COLOR; SKIN PIGMENTATION; STOP CODON; ZEBRA FISH;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL EVOLUTION; CLONING, MOLECULAR; HOMEOSTASIS; HUMANS; HYDROGEN-ION CONCENTRATION; MELANOCYTES; MELANOPHORES; MELANOSOMES; MEMBRANE TRANSPORT PROTEINS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MONOPHENOL MONOOXYGENASE; MORPHOLINOS; MUTATION; NEURAL CREST; ORGAN SPECIFICITY; PIGMENTATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RETINA; VACUOLAR PROTON-TRANSLOCATING ATPASES; VISUAL ACUITY; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84874382632     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/pcmr.12053     Document Type: Article

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