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Volumn 43, Issue 5, 2016, Pages 251-262

Targeted Gene Manipulation in Plants Using the CRISPR/Cas Technology

Author keywords

CRISPR Cas technology; Gene knockout; Genome editing; Plants

Indexed keywords

CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENOME; KNOCKOUT GENE; MAMMAL; ANIMAL; CRISPR CAS SYSTEM; GENE EDITING; GENETICS; GENOMICS; HUMAN; PLANT; PLANT GENOME; PROCEDURES;

EID: 84975179107     PISSN: 16738527     EISSN: 18735533     Source Type: Journal    
DOI: 10.1016/j.jgg.2016.03.001     Document Type: Review
Times cited : (57)

References (112)
  • 3
    • 84896308706 scopus 로고    scopus 로고
    • Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases
    • Bae, S., Park, J., Kim, J.S., Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases. Bioinformatics 30 (2014), 1473–1475.
    • (2014) Bioinformatics , vol.30 , pp. 1473-1475
    • Bae, S.1    Park, J.2    Kim, J.S.3
  • 7
    • 84908584019 scopus 로고    scopus 로고
    • Efficient gene editing in tomato in the first generation using the clustered regularly interspaced short palindromic repeats/CRISPR-associated 9 system
    • Brooks, C., Nekrasov, V., Lippman, Z.B., Van Eck, J., Efficient gene editing in tomato in the first generation using the clustered regularly interspaced short palindromic repeats/CRISPR-associated 9 system. Plant Physiol. 166 (2014), 1292–1297.
    • (2014) Plant Physiol. , vol.166 , pp. 1292-1297
    • Brooks, C.1    Nekrasov, V.2    Lippman, Z.B.3    Van Eck, J.4
  • 8
    • 84957112148 scopus 로고    scopus 로고
    • Generation and inheritance of targeted mutations in potato (Solanum tuberosum L.) using the CRISPR/Cas system
    • Butler, N.M., Atkins, P.A., Voytas, D.F., Douches, D.S., Generation and inheritance of targeted mutations in potato (Solanum tuberosum L.) using the CRISPR/Cas system. PLoS One, 10, 2015, e0144591.
    • (2015) PLoS One , vol.10 , pp. e0144591
    • Butler, N.M.1    Atkins, P.A.2    Voytas, D.F.3    Douches, D.S.4
  • 9
    • 84942418558 scopus 로고    scopus 로고
    • CRISPR/Cas9-mediated genome editing in soybean hairy roots
    • Cai, Y., Chen, L., Liu, X., Sun, S., Wu, C., Jiang, B., Han, T., Hou, W., CRISPR/Cas9-mediated genome editing in soybean hairy roots. PLoS One, 10, 2015, e0136064.
    • (2015) PLoS One , vol.10 , pp. e0136064
    • Cai, Y.1    Chen, L.2    Liu, X.3    Sun, S.4    Wu, C.5    Jiang, B.6    Han, T.7    Hou, W.8
  • 11
    • 84940501210 scopus 로고    scopus 로고
    • Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach
    • Chari, R., Mali, P., Moosburner, M., Church, G.M., Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach. Nat. Methods 12 (2015), 823–826.
    • (2015) Nat. Methods , vol.12 , pp. 823-826
    • Chari, R.1    Mali, P.2    Moosburner, M.3    Church, G.M.4
  • 14
    • 84952636633 scopus 로고    scopus 로고
    • Optimizing sgRNA structure to improve CRISPR-Cas9 knockout efficiency
    • Dang, Y., Jia, G., Choi, J., Ma, H., Anaya, E., Ye, C., Shankar, P., Wu, H., Optimizing sgRNA structure to improve CRISPR-Cas9 knockout efficiency. Genome Biol., 16, 2015, 280.
    • (2015) Genome Biol. , vol.16 , pp. 280
    • Dang, Y.1    Jia, G.2    Choi, J.3    Ma, H.4    Anaya, E.5    Ye, C.6    Shankar, P.7    Wu, H.8
  • 16
    • 84913594397 scopus 로고    scopus 로고
    • The new frontier of genome engineering with CRISPR-Cas9
    • Doudna, J.A., Charpentier, E., The new frontier of genome engineering with CRISPR-Cas9. Science, 346, 2014, 1258096.
    • (2014) Science , vol.346 , pp. 1258096
    • Doudna, J.A.1    Charpentier, E.2
  • 17
    • 84960367126 scopus 로고    scopus 로고
    • Efficient targeted mutagenesis in soybean by TALENs and CRISPR/Cas9
    • Du, H., Zeng, X., Zhao, M., Cui, X., Wang, Q., Yang, H., Cheng, H., Yu, D., Efficient targeted mutagenesis in soybean by TALENs and CRISPR/Cas9. J. Biotechnol. 217 (2016), 90–97.
    • (2016) J. Biotechnol. , vol.217 , pp. 90-97
    • Du, H.1    Zeng, X.2    Zhao, M.3    Cui, X.4    Wang, Q.5    Yang, H.6    Cheng, H.7    Yu, D.8
  • 18
    • 84952639763 scopus 로고    scopus 로고
    • Identification of a regulatory element responsible for salt induction of rice OsRAV2 through ex situ and in situ promoter analysis
    • Duan, Y.B., Li, J., Qin, R.Y., Xu, R.F., Li, H., Yang, Y.C., Ma, H., Li, L., Wei, P.C., Yang, J.B., Identification of a regulatory element responsible for salt induction of rice OsRAV2 through ex situ and in situ promoter analysis. Plant Mol. Biol. 90 (2016), 49–62.
    • (2016) Plant Mol. Biol. , vol.90 , pp. 49-62
    • Duan, Y.B.1    Li, J.2    Qin, R.Y.3    Xu, R.F.4    Li, H.5    Yang, Y.C.6    Ma, H.7    Li, L.8    Wei, P.C.9    Yang, J.B.10
  • 19
    • 84922664019 scopus 로고    scopus 로고
    • Multigene knockout utilizing off-target mutations of the CRISPR/Cas9 system in rice
    • Endo, M., Mikami, M., Toki, S., Multigene knockout utilizing off-target mutations of the CRISPR/Cas9 system in rice. Plant Cell Physiol. 56 (2015), 41–47.
    • (2015) Plant Cell Physiol. , vol.56 , pp. 41-47
    • Endo, M.1    Mikami, M.2    Toki, S.3
  • 20
    • 84956760665 scopus 로고    scopus 로고
    • Bi-allelic gene targeting in rice
    • Endo, M., Mikami, M., Toki, S., Bi-allelic gene targeting in rice. Plant Physiol. 170 (2016), 667–677.
    • (2016) Plant Physiol. , vol.170 , pp. 667-677
    • Endo, M.1    Mikami, M.2    Toki, S.3
  • 22
    • 84937702694 scopus 로고    scopus 로고
    • Efficient CRISPR/Cas9-mediated targeted mutagenesis in Populus in the first generation
    • Fan, D., Liu, T., Li, C., Jiao, B., Li, S., Hou, Y., Luo, K., Efficient CRISPR/Cas9-mediated targeted mutagenesis in Populus in the first generation. Sci. Rep., 5, 2015, 12217.
    • (2015) Sci. Rep. , vol.5 , pp. 12217
    • Fan, D.1    Liu, T.2    Li, C.3    Jiao, B.4    Li, S.5    Hou, Y.6    Luo, K.7
  • 23
    • 84904068340 scopus 로고    scopus 로고
    • Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering in Arabidopsis thaliana
    • Fauser, F., Schiml, S., Puchta, H., Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering in Arabidopsis thaliana. Plant J. 79 (2014), 348–359.
    • (2014) Plant J. , vol.79 , pp. 348-359
    • Fauser, F.1    Schiml, S.2    Puchta, H.3
  • 27
    • 84896929630 scopus 로고    scopus 로고
    • Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
    • Fu, Y., Sander, J.D., Reyon, D., Cascio, V.M., Joung, J.K., Improving CRISPR-Cas nuclease specificity using truncated guide RNAs. Nat. Biotechnol. 32 (2014), 279–284.
    • (2014) Nat. Biotechnol. , vol.32 , pp. 279-284
    • Fu, Y.1    Sander, J.D.2    Reyon, D.3    Cascio, V.M.4    Joung, J.K.5
  • 29
    • 84879264708 scopus 로고    scopus 로고
    • ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
    • Gaj, T., Gersbach, C.A., Barbas, C.F., ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol. 31 (2013), 397–405.
    • (2013) Trends Biotechnol. , vol.31 , pp. 397-405
    • Gaj, T.1    Gersbach, C.A.2    Barbas, C.F.3
  • 31
    • 84923164523 scopus 로고    scopus 로고
    • Auxin binding protein 1 (ABP1) is not required for either auxin signaling or Arabidopsis development
    • Gao, Y., Zhang, Y., Zhang, D., Dai, X., Estelle, M., Zhao, Y., Auxin binding protein 1 (ABP1) is not required for either auxin signaling or Arabidopsis development. Proc. Natl. Acad. Sci. USA 112 (2015), 2275–2280.
    • (2015) Proc. Natl. Acad. Sci. USA , vol.112 , pp. 2275-2280
    • Gao, Y.1    Zhang, Y.2    Zhang, D.3    Dai, X.4    Estelle, M.5    Zhao, Y.6
  • 34
    • 84920435758 scopus 로고    scopus 로고
    • Site-directed mutagenesis in Arabidopsis thaliana using dividing tissue-targeted RGEN of the CRISPR/Cas system to generate heritable null alleles
    • Hyun, Y., Kim, J., Cho, S.W., Choi, Y., Kim, J.S., Coupland, G., Site-directed mutagenesis in Arabidopsis thaliana using dividing tissue-targeted RGEN of the CRISPR/Cas system to generate heritable null alleles. Planta 241 (2015), 271–284.
    • (2015) Planta , vol.241 , pp. 271-284
    • Hyun, Y.1    Kim, J.2    Cho, S.W.3    Choi, Y.4    Kim, J.S.5    Coupland, G.6
  • 35
    • 84944937432 scopus 로고    scopus 로고
    • CRISPR/Cas9-mediated mutagenesis of the RIN locus that regulates tomato fruit ripening
    • Ito, Y., Nishizawa-Yokoi, A., Endo, M., Mikami, M., Toki, S., CRISPR/Cas9-mediated mutagenesis of the RIN locus that regulates tomato fruit ripening. Biochem. Biophys. Res. Commun. 467 (2015), 76–82.
    • (2015) Biochem. Biophys. Res. Commun. , vol.467 , pp. 76-82
    • Ito, Y.1    Nishizawa-Yokoi, A.2    Endo, M.3    Mikami, M.4    Toki, S.5
  • 37
    • 84947775797 scopus 로고    scopus 로고
    • Establishing a CRISPR-Cas-like immune system conferring DNA virus resistance in plants
    • Ji, X., Zhang, H., Zhang, Y., Wang, Y., Gao, C., Establishing a CRISPR-Cas-like immune system conferring DNA virus resistance in plants. Nat. Plants, 1, 2015, 15144.
    • (2015) Nat. Plants , vol.1 , pp. 15144
    • Ji, X.1    Zhang, H.2    Zhang, Y.3    Wang, Y.4    Gao, C.5
  • 38
    • 84899556051 scopus 로고    scopus 로고
    • Targeted genome editing of sweet orange using Cas9/sgRNA
    • Jia, H., Wang, N., Targeted genome editing of sweet orange using Cas9/sgRNA. PLoS One, 9, 2014, e93806.
    • (2014) PLoS One , vol.9 , pp. e93806
    • Jia, H.1    Wang, N.2
  • 39
    • 84908334356 scopus 로고    scopus 로고
    • Successful transient expression of Cas9 and single guide RNA genes in Chlamydomonas reinhardtii
    • Jiang, W., Brueggeman, A.J., Horken, K.M., Plucinak, T.M., Weeks, D.P., Successful transient expression of Cas9 and single guide RNA genes in Chlamydomonas reinhardtii. Eukaryot. Cell 13 (2014), 1465–1469.
    • (2014) Eukaryot. Cell , vol.13 , pp. 1465-1469
    • Jiang, W.1    Brueggeman, A.J.2    Horken, K.M.3    Plucinak, T.M.4    Weeks, D.P.5
  • 40
    • 84903398817 scopus 로고    scopus 로고
    • Efficient CRISPR/Cas9-mediated gene editing in Arabidopsis thaliana and inheritance of modified genes in the T2 and T3 generations
    • Jiang, W., Yang, B., Weeks, D.P., Efficient CRISPR/Cas9-mediated gene editing in Arabidopsis thaliana and inheritance of modified genes in the T2 and T3 generations. PLoS One, 9, 2014, e99225.
    • (2014) PLoS One , vol.9 , pp. e99225
    • Jiang, W.1    Yang, B.2    Weeks, D.P.3
  • 41
    • 84886926151 scopus 로고    scopus 로고
    • Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice
    • Jiang, W., Zhou, H., Bi, H., Fromm, M., Yang, B., Weeks, D.P., Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice. Nucleic Acids Res., 41, 2013, e188.
    • (2013) Nucleic Acids Res. , vol.41 , pp. e188
    • Jiang, W.1    Zhou, H.2    Bi, H.3    Fromm, M.4    Yang, B.5    Weeks, D.P.6
  • 42
    • 84865070369 scopus 로고    scopus 로고
    • A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
    • Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J.A., Charpentier, E., A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337 (2012), 816–821.
    • (2012) Science , vol.337 , pp. 816-821
    • Jinek, M.1    Chylinski, K.2    Fonfara, I.3    Hauer, M.4    Doudna, J.A.5    Charpentier, E.6
  • 43
    • 85027948074 scopus 로고    scopus 로고
    • Comparative assessments of CRISPR-Cas nucleases' cleavage efficiency in planta
    • Johnson, R.A., Gurevich, V., Filler, S., Samach, A., Levy, A.A., Comparative assessments of CRISPR-Cas nucleases' cleavage efficiency in planta. Plant Mol. Biol. 87 (2015), 143–156.
    • (2015) Plant Mol. Biol. , vol.87 , pp. 143-156
    • Johnson, R.A.1    Gurevich, V.2    Filler, S.3    Samach, A.4    Levy, A.A.5
  • 48
    • 84948761978 scopus 로고    scopus 로고
    • Induction of targeted, heritable mutations in barley and Brassica oleracea using RNA-guided Cas9 nuclease
    • Lawrenson, T., Shorinola, O., Stacey, N., Li, C., Ostergaard, L., Patron, N., Uauy, C., Harwood, W., Induction of targeted, heritable mutations in barley and Brassica oleracea using RNA-guided Cas9 nuclease. Genome Biol., 16, 2015, 258.
    • (2015) Genome Biol. , vol.16 , pp. 258
    • Lawrenson, T.1    Shorinola, O.2    Stacey, N.3    Li, C.4    Ostergaard, L.5    Patron, N.6    Uauy, C.7    Harwood, W.8
  • 49
    • 84922596582 scopus 로고    scopus 로고
    • CRISPR-P: a web tool for synthetic single-guide RNA design of CRISPR-system in plants
    • Lei, Y., Lu, L., Liu, H.Y., Li, S., Xing, F., Chen, L.L., CRISPR-P: a web tool for synthetic single-guide RNA design of CRISPR-system in plants. Mol. Plant 7 (2014), 1494–1496.
    • (2014) Mol. Plant , vol.7 , pp. 1494-1496
    • Lei, Y.1    Lu, L.2    Liu, H.Y.3    Li, S.4    Xing, F.5    Chen, L.L.6
  • 50
    • 84883785822 scopus 로고    scopus 로고
    • Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9
    • Li, J.F., Norville, J.E., Aach, J., McCormack, M., Zhang, D., Bush, J., Church, G.M., Sheen, J., Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9. Nat. Biotechnol. 31 (2013), 688–691.
    • (2013) Nat. Biotechnol. , vol.31 , pp. 688-691
    • Li, J.F.1    Norville, J.E.2    Aach, J.3    McCormack, M.4    Zhang, D.5    Bush, J.6    Church, G.M.7    Sheen, J.8
  • 52
    • 84894321885 scopus 로고    scopus 로고
    • Targeted mutagenesis in Zea mays using TALENs and the CRISPR/Cas system
    • Liang, Z., Zhang, K., Chen, K., Gao, C., Targeted mutagenesis in Zea mays using TALENs and the CRISPR/Cas system. J. Genet. Genomics 41 (2014), 63–68.
    • (2014) J. Genet. Genomics , vol.41 , pp. 63-68
    • Liang, Z.1    Zhang, K.2    Chen, K.3    Gao, C.4
  • 56
    • 84884160273 scopus 로고    scopus 로고
    • Cas9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
    • Mali, P., Aach, J., Stranges, P.B., Esvelt, K.M., Moosburner, M., Kosuri, S., Yang, L., Church, G.M., Cas9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nat. Biotechnol. 31 (2013), 833–838.
    • (2013) Nat. Biotechnol. , vol.31 , pp. 833-838
    • Mali, P.1    Aach, J.2    Stranges, P.B.3    Esvelt, K.M.4    Moosburner, M.5    Kosuri, S.6    Yang, L.7    Church, G.M.8
  • 59
    • 84891932593 scopus 로고    scopus 로고
    • Application of the CRISPR-Cas system for efficient genome engineering in plants
    • Mao, Y., Zhang, H., Xu, N., Zhang, B., Gou, F., Zhu, J.K., Application of the CRISPR-Cas system for efficient genome engineering in plants. Mol. Plant 6 (2013), 2008–2011.
    • (2013) Mol. Plant , vol.6 , pp. 2008-2011
    • Mao, Y.1    Zhang, H.2    Xu, N.3    Zhang, B.4    Gou, F.5    Zhu, J.K.6
  • 60
    • 84941312953 scopus 로고    scopus 로고
    • Development of germ-line-specific CRISPR-Cas9 systems to improve the production of heritable gene modifications in Arabidopsis
    • Mao, Y., Zhang, Z., Feng, Z., Wei, P., Zhang, H., Botella, J.R., Zhu, J.K., Development of germ-line-specific CRISPR-Cas9 systems to improve the production of heritable gene modifications in Arabidopsis. Plant Biotechnol. J. 14 (2016), 519–532.
    • (2016) Plant Biotechnol. J. , vol.14 , pp. 519-532
    • Mao, Y.1    Zhang, Z.2    Feng, Z.3    Wei, P.4    Zhang, H.5    Botella, J.R.6    Zhu, J.K.7
  • 61
    • 84893435357 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticle-mediated intracellular cre protein delivery for maize genome editing via loxP site excision
    • Martin-Ortigosa, S., Peterson, D.J., Valenstein, J.S., Lin, V.S., Trewyn, B.G., Lyznik, L.A., Wang, K., Mesoporous silica nanoparticle-mediated intracellular cre protein delivery for maize genome editing via loxP site excision. Plant Physiol. 164 (2014), 537–547.
    • (2014) Plant Physiol. , vol.164 , pp. 537-547
    • Martin-Ortigosa, S.1    Peterson, D.J.2    Valenstein, J.S.3    Lin, V.S.4    Trewyn, B.G.5    Lyznik, L.A.6    Wang, K.7
  • 63
    • 85013017478 scopus 로고    scopus 로고
    • CRISPR/Cas mutagenesis of soybean and Medicago truncatula using a new web-tool and a modified Cas9 enzyme
    • Michno, J.M., Wang, X., Liu, J., Curtin, S.J., Kono, T.J.Y., Stupar, R.M., CRISPR/Cas mutagenesis of soybean and Medicago truncatula using a new web-tool and a modified Cas9 enzyme. GM Crops Food. 6 (2015), 243–252.
    • (2015) GM Crops Food. , vol.6 , pp. 243-252
    • Michno, J.M.1    Wang, X.2    Liu, J.3    Curtin, S.J.4    Kono, T.J.Y.5    Stupar, R.M.6
  • 64
    • 84938551854 scopus 로고    scopus 로고
    • Comparison of CRISPR/Cas9 expression constructs for efficient targeted mutagenesis in rice
    • Mikami, M., Toki, S., Endo, M., Comparison of CRISPR/Cas9 expression constructs for efficient targeted mutagenesis in rice. Plant Mol. Biol. 88 (2015), 561–572.
    • (2015) Plant Mol. Biol. , vol.88 , pp. 561-572
    • Mikami, M.1    Toki, S.2    Endo, M.3
  • 65
    • 84941941829 scopus 로고    scopus 로고
    • Parameters affecting frequency of CRISPR/Cas9 mediated targeted mutagenesis in rice
    • Mikami, M., Toki, S., Endo, M., Parameters affecting frequency of CRISPR/Cas9 mediated targeted mutagenesis in rice. Plant Cell Rep. 34 (2015), 1807–1815.
    • (2015) Plant Cell Rep. , vol.34 , pp. 1807-1815
    • Mikami, M.1    Toki, S.2    Endo, M.3
  • 66
    • 84883828590 scopus 로고    scopus 로고
    • Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease
    • Nekrasov, V., Staskawicz, B., Weigel, D., Jones, J.D.G., Kamoun, S., Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease. Nat. Biotechnol. 31 (2013), 691–693.
    • (2013) Nat. Biotechnol. , vol.31 , pp. 691-693
    • Nekrasov, V.1    Staskawicz, B.2    Weigel, D.3    Jones, J.D.G.4    Kamoun, S.5
  • 67
    • 84936768524 scopus 로고    scopus 로고
    • Two novel NAC transcription factors regulate gene expression and flowering time by associating with the histone demethylase JMJ14
    • Ning, Y.Q., Ma, Z.Y., Huang, H.W., Mo, H., Zhao, T.T., Li, L., Cai, T., Chen, S., Ma, L., He, X.J., Two novel NAC transcription factors regulate gene expression and flowering time by associating with the histone demethylase JMJ14. Nucleic. Acids Res. 43 (2015), 1469–1484.
    • (2015) Nucleic. Acids Res. , vol.43 , pp. 1469-1484
    • Ning, Y.Q.1    Ma, Z.Y.2    Huang, H.W.3    Mo, H.4    Zhao, T.T.5    Li, L.6    Cai, T.7    Chen, S.8    Ma, L.9    He, X.J.10
  • 72
    • 84901386271 scopus 로고    scopus 로고
    • Synthetic nucleases for genome engineering in plants: prospects for a bright future
    • Puchta, H., Fauser, F., Synthetic nucleases for genome engineering in plants: prospects for a bright future. Plant J. 78 (2014), 727–741.
    • (2014) Plant J. , vol.78 , pp. 727-741
    • Puchta, H.1    Fauser, F.2
  • 73
    • 84874687019 scopus 로고    scopus 로고
    • Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
    • Qi, L.S., Larson, M.H., Gilbert, L.A., Doudna, J.A., Weissman, J.S., Arkin, A.P., Lim, W.A., Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell 152 (2013), 1173–1183.
    • (2013) Cell , vol.152 , pp. 1173-1183
    • Qi, L.S.1    Larson, M.H.2    Gilbert, L.A.3    Doudna, J.A.4    Weissman, J.S.5    Arkin, A.P.6    Lim, W.A.7
  • 77
    • 84941956073 scopus 로고    scopus 로고
    • CRISPR/Cas9-mediated genome editing and gene replacement in plants: transitioning from lab to field
    • Schaeffer, G.M., Nakata, P.A., CRISPR/Cas9-mediated genome editing and gene replacement in plants: transitioning from lab to field. Plant Sci. 240 (2015), 130–142.
    • (2015) Plant Sci. , vol.240 , pp. 130-142
    • Schaeffer, G.M.1    Nakata, P.A.2
  • 78
    • 84916624400 scopus 로고    scopus 로고
    • The CRISPR/Cas system can be used as nuclease for in planta gene targeting and as paired nickases for directed mutagenesis in Arabidopsis resulting in heritable progeny
    • Schiml, S., Fauser, F., Puchta, H., The CRISPR/Cas system can be used as nuclease for in planta gene targeting and as paired nickases for directed mutagenesis in Arabidopsis resulting in heritable progeny. Plant J. 80 (2014), 1139–1150.
    • (2014) Plant J. , vol.80 , pp. 1139-1150
    • Schiml, S.1    Fauser, F.2    Puchta, H.3
  • 81
    • 84961350912 scopus 로고    scopus 로고
    • Highly efficient heritable plant genome engineering using Cas9 orthologues from Streptococcus thermophiles and Staphylococcus aureus
    • Steinert, J., Schiml, S., Fauser, F., Puchta, H., Highly efficient heritable plant genome engineering using Cas9 orthologues from Streptococcus thermophiles and Staphylococcus aureus. Plant J. 84 (2015), 1295–1305.
    • (2015) Plant J. , vol.84 , pp. 1295-1305
    • Steinert, J.1    Schiml, S.2    Fauser, F.3    Puchta, H.4
  • 82
    • 84895871173 scopus 로고    scopus 로고
    • DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
    • Sternberg, S.H., Redding, S., Jinek, M., Greene, E.C., Doudna, J.A., DNA interrogation by the CRISPR RNA-guided endonuclease Cas9. Nature 507 (2014), 62–67.
    • (2014) Nature , vol.507 , pp. 62-67
    • Sternberg, S.H.1    Redding, S.2    Jinek, M.3    Greene, E.C.4    Doudna, J.A.5
  • 84
    • 84930651072 scopus 로고    scopus 로고
    • Targeted mutagenesis in soybean using the CRISPR-Cas9 system
    • Sun, X., Hu, Z., Chen, R., Jiang, Q., Song, G., Zhang, H., Xi, Y., Targeted mutagenesis in soybean using the CRISPR-Cas9 system. Sci. Rep., 5, 2015, 10342.
    • (2015) Sci. Rep. , vol.5 , pp. 10342
    • Sun, X.1    Hu, Z.2    Chen, R.3    Jiang, Q.4    Song, G.5    Zhang, H.6    Xi, Y.7
  • 85
    • 84942901283 scopus 로고    scopus 로고
    • Targeted mutagenesis, precise genome editing, and site-specific gene insertion in maize using Cas9 and guide RNA
    • Svitashev, S., Young, J.K., Schwartz, C., Gao, H., Falco, S.C., Cigan, A.M., Targeted mutagenesis, precise genome editing, and site-specific gene insertion in maize using Cas9 and guide RNA. Plant Physiol. 169 (2015), 931–945.
    • (2015) Plant Physiol. , vol.169 , pp. 931-945
    • Svitashev, S.1    Young, J.K.2    Schwartz, C.3    Gao, H.4    Falco, S.C.5    Cigan, A.M.6
  • 86
    • 84908328232 scopus 로고    scopus 로고
    • A protein-tagging system for signal amplification in gene expression and fluorescence imaging
    • Tanenbaum, M.E., Gilbert, L.A., Qi, L.S., Weissman, J.S., Vale, R.D., A protein-tagging system for signal amplification in gene expression and fluorescence imaging. Cell 159 (2014), 635–646.
    • (2014) Cell , vol.159 , pp. 635-646
    • Tanenbaum, M.E.1    Gilbert, L.A.2    Qi, L.S.3    Weissman, J.S.4    Vale, R.D.5
  • 89
    • 84890831873 scopus 로고    scopus 로고
    • RNA-guided genome editing for targeted gene mutations in wheat
    • Upadhyay, S.K., Kumar, J., Alok, A., Tuli, R., RNA-guided genome editing for targeted gene mutations in wheat. G3 3 (2013), 2233–2238.
    • (2013) G3 , vol.3 , pp. 2233-2238
    • Upadhyay, S.K.1    Kumar, J.2    Alok, A.3    Tuli, R.4
  • 90
    • 84874627868 scopus 로고    scopus 로고
    • Plant genome engineering with sequence-specific nucleases
    • Voytas, D.F., Plant genome engineering with sequence-specific nucleases. Annu. Rev. Plant Biol. 64 (2013), 327–350.
    • (2013) Annu. Rev. Plant Biol. , vol.64 , pp. 327-350
    • Voytas, D.F.1
  • 91
    • 84921934205 scopus 로고    scopus 로고
    • Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew
    • Wang, Y., Cheng, X., Shan, Q., Zhang, Y., Liu, J., Gao, C., Qiu, J.L., Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. Nat. Biotechnol. 32 (2014), 947–951.
    • (2014) Nat. Biotechnol. , vol.32 , pp. 947-951
    • Wang, Y.1    Cheng, X.2    Shan, Q.3    Zhang, Y.4    Liu, J.5    Gao, C.6    Qiu, J.L.7
  • 92
    • 84892749369 scopus 로고    scopus 로고
    • Genetic screens in human cells using the CRISPR-Cas9 system
    • Wang, T., Wei, J.J., Sabatini, D.M., Lander, E.S., Genetic screens in human cells using the CRISPR-Cas9 system. Science 343 (2014), 80–84.
    • (2014) Science , vol.343 , pp. 80-84
    • Wang, T.1    Wei, J.J.2    Sabatini, D.M.3    Lander, E.S.4
  • 93
    • 84937568562 scopus 로고    scopus 로고
    • Egg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation
    • Wang, Z.P., Xing, H.L., Dong, L., Zhang, H.Y., Han, C.Y., Wang, X.C., Chen, Q.J., Egg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation. Genome Biol., 16, 2015, 144.
    • (2015) Genome Biol. , vol.16 , pp. 144
    • Wang, Z.P.1    Xing, H.L.2    Dong, L.3    Zhang, H.Y.4    Han, C.Y.5    Wang, X.C.6    Chen, Q.J.7
  • 94
    • 84938988571 scopus 로고    scopus 로고
    • Efficient targeted mutagenesis in potato by the CRISPR/Cas9 system
    • Wang, S., Zhang, S., Wang, W., Xiong, X., Meng, F., Cui, X., Efficient targeted mutagenesis in potato by the CRISPR/Cas9 system. Plant Cell Rep. 34 (2015), 1473–1476.
    • (2015) Plant Cell Rep. , vol.34 , pp. 1473-1476
    • Wang, S.1    Zhang, S.2    Wang, W.3    Xiong, X.4    Meng, F.5    Cui, X.6
  • 95
    • 84939191325 scopus 로고    scopus 로고
    • Use of designer nucleases for targeted gene and genome editing in plants
    • Weeks, D.P., Spalding, M.H., Yang, B., Use of designer nucleases for targeted gene and genome editing in plants. Plant Biotechnol. J. 14 (2016), 483–495.
    • (2016) Plant Biotechnol. J. , vol.14 , pp. 483-495
    • Weeks, D.P.1    Spalding, M.H.2    Yang, B.3
  • 97
    • 84925262435 scopus 로고    scopus 로고
    • Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system
    • Xie, K., Minkenberg, B., Yang, Y., Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system. Proc. Natl. Acad. Sci. USA 112 (2015), 3570–3575.
    • (2015) Proc. Natl. Acad. Sci. USA , vol.112 , pp. 3570-3575
    • Xie, K.1    Minkenberg, B.2    Yang, Y.3
  • 98
    • 84884962826 scopus 로고    scopus 로고
    • RNA-guided genome editing in plants using a CRISPR-Cas system
    • Xie, K., Yang, Y., RNA-guided genome editing in plants using a CRISPR-Cas system. Mol. Plant 6 (2013), 1975–1983.
    • (2013) Mol. Plant , vol.6 , pp. 1975-1983
    • Xie, K.1    Yang, Y.2
  • 99
    • 84899895901 scopus 로고    scopus 로고
    • Genome-wide prediction of highly specific guide RNA spacers for CRISPR-Cas9-mediated genome editing in model plants and major crops
    • Xie, K., Zhang, J., Yang, Y., Genome-wide prediction of highly specific guide RNA spacers for CRISPR-Cas9-mediated genome editing in model plants and major crops. Mol. Plant 7 (2014), 923–926.
    • (2014) Mol. Plant , vol.7 , pp. 923-926
    • Xie, K.1    Zhang, J.2    Yang, Y.3
  • 101
    • 84938551842 scopus 로고    scopus 로고
    • Gene targeting using the Agrobacterium tumefaciens-mediated CRISPR-Cas system in rice
    • Xu, R.F., Li, H., Qin, R., Wang, L., Li, L., Wei, P., Yang, J., Gene targeting using the Agrobacterium tumefaciens-mediated CRISPR-Cas system in rice. Rice, 7, 2014, 5.
    • (2014) Rice , vol.7 , pp. 5
    • Xu, R.F.1    Li, H.2    Qin, R.3    Wang, L.4    Li, L.5    Wei, P.6    Yang, J.7
  • 102
    • 84935033103 scopus 로고    scopus 로고
    • Generation of inheritable and “transgene clean” targeted genome-modified rice in later generations using the CRISPR/Cas9 system
    • Xu, R.F., Li, H., Qin, R.Y., Li, J., Qiu, C.H., Yang, Y.C., Ma, H., Li, L., Wei, P.C., Yang, J.B., Generation of inheritable and “transgene clean” targeted genome-modified rice in later generations using the CRISPR/Cas9 system. Sci. Rep., 5, 2015, 11491.
    • (2015) Sci. Rep. , vol.5 , pp. 11491
    • Xu, R.F.1    Li, H.2    Qin, R.Y.3    Li, J.4    Qiu, C.H.5    Yang, Y.C.6    Ma, H.7    Li, L.8    Wei, P.C.9    Yang, J.B.10
  • 103
    • 84947723842 scopus 로고    scopus 로고
    • High efficiency genome editing in Arabidopsis using YAO promoter-driven CRISPR/Cas9 system
    • Yan, L., Wei, S., Wu, Y., Hu, R., Li, H., Yang, W., Xie, Q., High efficiency genome editing in Arabidopsis using YAO promoter-driven CRISPR/Cas9 system. Mol. Plant 8 (2015), 1820–1823.
    • (2015) Mol. Plant , vol.8 , pp. 1820-1823
    • Yan, L.1    Wei, S.2    Wu, Y.3    Hu, R.4    Li, H.5    Yang, W.6    Xie, Q.7
  • 104
    • 84934438984 scopus 로고    scopus 로고
    • CRISPR Primer Designer: Design primers for knockout and chromosome imaging CRISPR-Cas system
    • Yan, M., Zhou, S.R., Xue, H.W., CRISPR Primer Designer: Design primers for knockout and chromosome imaging CRISPR-Cas system. J. Integr. Plant Biol. 57 (2015), 613–617.
    • (2015) J. Integr. Plant Biol. , vol.57 , pp. 613-617
    • Yan, M.1    Zhou, S.R.2    Xue, H.W.3
  • 105
    • 84943602335 scopus 로고    scopus 로고
    • A geminivirus-based guide RNA delivery system for CRISPR/Cas9 mediated plant genome editing
    • Yin, K., Han, T., Liu, G., Chen, T., Wang, Y., Yu, A.Y.L., Liu, Y., A geminivirus-based guide RNA delivery system for CRISPR/Cas9 mediated plant genome editing. Sci. Rep., 5, 2015, 14926.
    • (2015) Sci. Rep. , vol.5 , pp. 14926
    • Yin, K.1    Han, T.2    Liu, G.3    Chen, T.4    Wang, Y.5    Yu, A.Y.L.6    Liu, Y.7
  • 108
    • 84949557262 scopus 로고    scopus 로고
    • A multiplex CRISPR/Cas9 platform for fast and efficient editing of multiple genes in Arabidopsis
    • Zhang, Z., Mao, Y., Ha, S., Liu, W., Botella, J.R., Zhu, J.K., A multiplex CRISPR/Cas9 platform for fast and efficient editing of multiple genes in Arabidopsis. Plant Cell Rep., 2015, 10.1007/s00299-015-1900-z.
    • (2015) Plant Cell Rep.
    • Zhang, Z.1    Mao, Y.2    Ha, S.3    Liu, W.4    Botella, J.R.5    Zhu, J.K.6
  • 109
    • 84988940483 scopus 로고    scopus 로고
    • Genome editing: new antiviral weapon for plants
    • Zhang, D., Li, Z., Li, J.F., Genome editing: new antiviral weapon for plants. Nat. Plants, 1, 2015, 15146.
    • (2015) Nat. Plants , vol.1 , pp. 15146
    • Zhang, D.1    Li, Z.2    Li, J.F.3
  • 110
    • 84921549293 scopus 로고    scopus 로고
    • Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice
    • Zhou, H., Liu, B., Weeks, D.P., Spalding, M.H., Yang, B., Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice. Nucleic Acids Res. 42 (2014), 10903–10914.
    • (2014) Nucleic Acids Res. , vol.42 , pp. 10903-10914
    • Zhou, H.1    Liu, B.2    Weeks, D.P.3    Spalding, M.H.4    Yang, B.5
  • 112
    • 84942827085 scopus 로고    scopus 로고
    • Exploiting SNPs for biallelic CRISPR mutations in the outcrossing woody perennial Populus reveals 4-coumarate: CoA ligase specificity and redundancy
    • Zhou, X., Jacobs, T.B., Xue, L.J., Harding, S.A., Tsai, C.J., Exploiting SNPs for biallelic CRISPR mutations in the outcrossing woody perennial Populus reveals 4-coumarate: CoA ligase specificity and redundancy. New Phytol. 208 (2015), 298–301.
    • (2015) New Phytol. , vol.208 , pp. 298-301
    • Zhou, X.1    Jacobs, T.B.2    Xue, L.J.3    Harding, S.A.4    Tsai, C.J.5


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