PAM multiplicity marks genomic target sites as inhibitory to CRISPR-Cas9 editing

Nature Communications

Volumn 6, Issue , 2015, Pages

  Malina, Abba ^a   Cameron, Christopher J F ^b   Robert, Francis ^a   Blanchette, Mathieu ^b   Dostie, Josée ^a,c   Pelletier, Jerry ^a,c  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CAS9 PROTEIN; CRISPR ASSOCIATED PROTEIN; GUANINE QUADRUPLEX; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; GUIDE RNA; RNA;

DESIGN; DNA; GENE EXPRESSION; GENOME; GENOMICS; RNA;

ARTICLE; CONTROLLED STUDY; DNA BASE COMPOSITION; DNA MODIFICATION; DNA SEQUENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTOSPACER ADJACENT MOTIF; CHEMISTRY; CRISPR CAS SYSTEM; DNA CLEAVAGE; GEL MOBILITY SHIFT ASSAY; GENOME; HEK293 CELL LINE; HELA CELL LINE; MCF-7 CELL LINE; METABOLISM; NORTHERN BLOTTING; NUCLEOTIDE MOTIF; RNA EDITING; WESTERN BLOTTING;

BLOTTING, NORTHERN; BLOTTING, WESTERN; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; DNA CLEAVAGE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENOME; HEK293 CELLS; HELA CELLS; HUMANS; MCF-7 CELLS; NUCLEOTIDE MOTIFS; RNA; RNA EDITING; RNA, GUIDE;

EID: 84949526143     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10124     Document Type: Article

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