-
1
-
-
84924953006
-
Ecdysone response gene E78 controls ovarian germline stem cell niche formation and follicle survival in Drosophila
-
E.T. Ables, K.E. Bois, C.A. Garcia, and D. Drummond-Barbosa Ecdysone response gene E78 controls ovarian germline stem cell niche formation and follicle survival in Drosophila Dev. Biol. 400 2015 33 42
-
(2015)
Dev. Biol.
, vol.400
, pp. 33-42
-
-
Ables, E.T.1
Bois, K.E.2
Garcia, C.A.3
Drummond-Barbosa, D.4
-
2
-
-
70449674487
-
Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)
-
A. Arlt, I. Bauer, C. Schafmayer, J. Tepel, S.S. Muerkoster, M. Brosch, C. Roder, H. Kalthoff, J. Hampe, M.P. Moyer, and et al. Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2) Oncogene 28 2009 3983 3996
-
(2009)
Oncogene
, vol.28
, pp. 3983-3996
-
-
Arlt, A.1
Bauer, I.2
Schafmayer, C.3
Tepel, J.4
Muerkoster, S.S.5
Brosch, M.6
Roder, C.7
Kalthoff, H.8
Hampe, J.9
Moyer, M.P.10
-
3
-
-
0015268582
-
Patterns of puffing activity in the salivary gland chromosomes of Drosophila. VII. Homology of puffing patterns on chromosome arm 3L in D. Melanogaster and D. Yakuba, with notes on puffing in D. Teissieri
-
M. Ashburner, and F. Lemeunier Patterns of puffing activity in the salivary gland chromosomes of Drosophila. VII. Homology of puffing patterns on chromosome arm 3L in D. melanogaster and D. yakuba, with notes on puffing in D. teissieri Chromosoma 38 1972 283 295
-
(1972)
Chromosoma
, vol.38
, pp. 283-295
-
-
Ashburner, M.1
Lemeunier, F.2
-
4
-
-
84884338770
-
Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex
-
L. Baird, D. Lleres, S. Swift, and A.T. Dinkova-Kostova Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex Proc. Natl. Acad. Sci. USA 110 2013 15259 15264
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 15259-15264
-
-
Baird, L.1
Lleres, D.2
Swift, S.3
Dinkova-Kostova, A.T.4
-
5
-
-
80052277569
-
Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease.
-
M.C. Barone, G.P. Sykiotis, and D. Bohmann Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease. Dis. Model. Mech. 4 2011 701 707
-
(2011)
Dis. Model. Mech.
, vol.4
, pp. 701-707
-
-
Barone, M.C.1
Sykiotis, G.P.2
Bohmann, D.3
-
6
-
-
61649121516
-
The UPS and autophagy in chronic neurodegenerative disease: Six of one and half a dozen of the other - Or not?
-
L. Bedford, S. Paine, N. Rezvani, M. Mee, J. Lowe, and R.J. Mayer The UPS and autophagy in chronic neurodegenerative disease: six of one and half a dozen of the other - or not? Autophagy 5 2009 224 227
-
(2009)
Autophagy
, vol.5
, pp. 224-227
-
-
Bedford, L.1
Paine, S.2
Rezvani, N.3
Mee, M.4
Lowe, J.5
Mayer, R.J.6
-
7
-
-
38049055294
-
Impaired liver regeneration in Nrf2 knockout mice: Role of ROS-mediated insulin/IGF-1 resistance
-
T.A. Beyer, W. Xu, D. Teupser, U. auf dem Keller, P. Bugnon, E. Hildt, J. Thiery, Y.W. Kan, and S. Werner Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance EMBO J 27 2008 212 223
-
(2008)
EMBO J
, vol.27
, pp. 212-223
-
-
Beyer, T.A.1
Xu, W.2
Teupser, D.3
Auf Dem Keller, U.4
Bugnon, P.5
Hildt, E.6
Thiery, J.7
Kan, Y.W.8
Werner, S.9
-
8
-
-
34249891333
-
Two neurons mediate diet-restriction-induced longevity in C. Elegans
-
N.A. Bishop, and L. Guarente Two neurons mediate diet-restriction-induced longevity in C. elegans Nature 447 2007 545 549
-
(2007)
Nature
, vol.447
, pp. 545-549
-
-
Bishop, N.A.1
Guarente, L.2
-
9
-
-
52949093944
-
JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut
-
B. Biteau, C.E. Hochmuth, and H. Jasper JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut Cell Stem Cell 3 2008 442 455
-
(2008)
Cell Stem Cell
, vol.3
, pp. 442-455
-
-
Biteau, B.1
Hochmuth, C.E.2
Jasper, H.3
-
10
-
-
0028104274
-
Formation of a monomeric DNA binding domain by Skn-1 bZIP and homeodomain elements
-
T.K. Blackwell, B. Bowerman, J.R. Priess, and H. Weintraub Formation of a monomeric DNA binding domain by Skn-1 bZIP and homeodomain elements Science 266 1994 621 628
-
(1994)
Science
, vol.266
, pp. 621-628
-
-
Blackwell, T.K.1
Bowerman, B.2
Priess, J.R.3
Weintraub, H.4
-
11
-
-
39049129643
-
Small Maf proteins in mammalian gene control: Mere dimerization partners or dynamic transcriptional regulators?
-
V. Blank Small Maf proteins in mammalian gene control: mere dimerization partners or dynamic transcriptional regulators? J. Mol. Biol 376 2008 913 925
-
(2008)
J. Mol. Biol
, vol.376
, pp. 913-925
-
-
Blank, V.1
-
12
-
-
27144522538
-
Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release
-
P.E. Caldwell, M. Walkiewicz, and M. Stern Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release Curr. Biol. 15 2005 1785 1795
-
(2005)
Curr. Biol.
, vol.15
, pp. 1785-1795
-
-
Caldwell, P.E.1
Walkiewicz, M.2
Stern, M.3
-
13
-
-
84922784813
-
Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis
-
P.A. Carroll, D. Diolaiti, L. McFerrin, H. Gu, D. Djukovic, J. Du, P.F. Cheng, S. Anderson, M. Ulrich, J.B. Hurley, and et al. Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis Cancer Cell 27 2015 271 285
-
(2015)
Cancer Cell
, vol.27
, pp. 271-285
-
-
Carroll, P.A.1
Diolaiti, D.2
McFerrin, L.3
Gu, H.4
Djukovic, D.5
Du, J.6
Cheng, P.F.7
Anderson, S.8
Ulrich, M.9
Hurley, J.B.10
-
14
-
-
0032536783
-
Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice
-
J.Y. Chan, M. Kwong, R. Lu, J. Chang, B. Wang, T.S. Yen, and Y.W. Kan Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice EMBO J. 17 1998 1779 1787
-
(1998)
EMBO J.
, vol.17
, pp. 1779-1787
-
-
Chan, J.Y.1
Kwong, M.2
Lu, R.3
Chang, J.4
Wang, B.5
Yen, T.S.6
Kan, Y.W.7
-
15
-
-
0030451213
-
Nrf2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development
-
K. Chan, R. Lu, J.C. Chang, and Y.W. Kan Nrf2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development Proc. Natl. Acad. Sci. USA 93 1996 13943 13948
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13943-13948
-
-
Chan, K.1
Lu, R.2
Chang, J.C.3
Kan, Y.W.4
-
16
-
-
84859592613
-
A versatile PhiC31 based reporter system for measuring AP-1 and Nrf2 signaling in Drosophila and in tissue culture
-
N. Chatterjee, and D. Bohmann A versatile PhiC31 based reporter system for measuring AP-1 and Nrf2 signaling in Drosophila and in tissue culture PLoS One 7 2012 e34063
-
(2012)
PLoS One
, vol.7
, pp. e34063
-
-
Chatterjee, N.1
Bohmann, D.2
-
17
-
-
0038382987
-
Nrf1 is critical for redox balance and survival of liver cells during development
-
L. Chen, M. Kwong, R. Lu, D. Ginzinger, C. Lee, L. Leung, and J.Y. Chan Nrf1 is critical for redox balance and survival of liver cells during development Mol. Cell. Biol. 23 2003 4673 4686
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 4673-4686
-
-
Chen, L.1
Kwong, M.2
Lu, R.3
Ginzinger, D.4
Lee, C.5
Leung, L.6
Chan, J.Y.7
-
18
-
-
66349105688
-
The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans
-
K.P. Choe, A.J. Przybysz, and K. Strange The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans Mol. Cell. Biol. 29 2009 2704 2715
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 2704-2715
-
-
Choe, K.P.1
Przybysz, A.J.2
Strange, K.3
-
19
-
-
84881476323
-
Nrf2 is controlled by two distinct beta-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity
-
S. Chowdhry, Y. Zhang, M. McMahon, C. Sutherland, A. Cuadrado, and J.D. Hayes Nrf2 is controlled by two distinct beta-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity Oncogene 32 2013 3765 3781
-
(2013)
Oncogene
, vol.32
, pp. 3765-3781
-
-
Chowdhry, S.1
Zhang, Y.2
McMahon, M.3
Sutherland, C.4
Cuadrado, A.5
Hayes, J.D.6
-
20
-
-
53149123284
-
Structure of the human 26S proteasome: Subunit radial displacements open the gate into the proteolytic core
-
P.C. da Fonseca, and E.P. Morris Structure of the human 26S proteasome: subunit radial displacements open the gate into the proteolytic core J. Biol. Chem. 283 2008 23305 23314
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 23305-23314
-
-
Da Fonseca, P.C.1
Morris, E.P.2
-
21
-
-
84859171807
-
MYC on the path to cancer
-
C.V. Dang MYC on the path to cancer Cell 149 2012 22 35
-
(2012)
Cell
, vol.149
, pp. 22-35
-
-
Dang, C.V.1
-
22
-
-
84874764624
-
Regulation of Drosophila metamorphosis by xenobiotic response regulators
-
H. Deng, and T.K. Kerppola Regulation of Drosophila metamorphosis by xenobiotic response regulators PLoS Genet. 9 2013 e1003263
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003263
-
-
Deng, H.1
Kerppola, T.K.2
-
23
-
-
84905483278
-
Visualization of the Drosophila dKeap1-CncC interaction on chromatin illumines cooperative, xenobiotic-specific gene activation
-
H. Deng, and T.K. Kerppola Visualization of the Drosophila dKeap1-CncC interaction on chromatin illumines cooperative, xenobiotic-specific gene activation Development 141 2014 3277 3288
-
(2014)
Development
, vol.141
, pp. 3277-3288
-
-
Deng, H.1
Kerppola, T.K.2
-
24
-
-
1842453034
-
Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus
-
A. Derjuga, T.S. Gourley, T.M. Holm, H.H. Heng, R.A. Shivdasani, R. Ahmed, N.C. Andrews, and V. Blank Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus Mol. Cell. Biol. 24 2004 3286 3294
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 3286-3294
-
-
Derjuga, A.1
Gourley, T.S.2
Holm, T.M.3
Heng, H.H.4
Shivdasani, R.A.5
Ahmed, R.6
Andrews, N.C.7
Blank, V.8
-
25
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
A.T. Dinkova-Kostova, W.D. Holtzclaw, R.N. Cole, K. Itoh, N. Wakabayashi, Y. Katoh, M. Yamamoto, and P. Talalay Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants Proc. Natl. Acad. Sci. USA 99 2002 11908 11913
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
Yamamoto, M.7
Talalay, P.8
-
26
-
-
84897374261
-
CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae
-
C.V. Edi, L. Djogbenou, A.M. Jenkins, K. Regna, M.A. Muskavitch, R. Poupardin, C.M. Jones, J. Essandoh, G.K. Ketoh, M.J. Paine, and et al. CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae PLoS Genet. 10 2014 e1004236
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004236
-
-
Edi, C.V.1
Djogbenou, L.2
Jenkins, A.M.3
Regna, K.4
Muskavitch, M.A.5
Poupardin, R.6
Jones, C.M.7
Essandoh, J.8
Ketoh, G.K.9
Paine, M.J.10
-
28
-
-
84937763512
-
New FDA-approved disease-modifying therapies for multiple sclerosis
-
C. English, and J.J. Aloi New FDA-approved disease-modifying therapies for multiple sclerosis Clin. Ther 2015
-
(2015)
Clin. Ther
-
-
English, C.1
Aloi, J.J.2
-
29
-
-
84893840509
-
Kinetic, thermodynamic, and structural characterizations of the association between Nrf2-DLGex degron and Keap1
-
T. Fukutomi, K. Takagi, T. Mizushima, N. Ohuchi, and M. Yamamoto Kinetic, thermodynamic, and structural characterizations of the association between Nrf2-DLGex degron and Keap1 Mol. Cell. Biol. 34 2014 832 846
-
(2014)
Mol. Cell. Biol.
, vol.34
, pp. 832-846
-
-
Fukutomi, T.1
Takagi, K.2
Mizushima, T.3
Ohuchi, N.4
Yamamoto, M.5
-
30
-
-
84873633910
-
Genetics of longevity in model organisms: Debates and paradigm shifts
-
D. Gems, and L. Partridge Genetics of longevity in model organisms: debates and paradigm shifts Annu. Rev. Physiol. 75 2013 621 644
-
(2013)
Annu. Rev. Physiol.
, vol.75
, pp. 621-644
-
-
Gems, D.1
Partridge, L.2
-
31
-
-
79251559085
-
Basic leucine zipper protein Cnc-C is a substrate and transcriptional regulator of the Drosophila 26S proteasome
-
K.B. Grimberg, A. Beskow, D. Lundin, M.M. Davis, and P. Young Basic leucine zipper protein Cnc-C is a substrate and transcriptional regulator of the Drosophila 26S proteasome Mol. Cell. Biol. 31 2011 897 909
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 897-909
-
-
Grimberg, K.B.1
Beskow, A.2
Lundin, D.3
Davis, M.M.4
Young, P.5
-
32
-
-
0028978186
-
A screen for modifiers of Deformed function in Drosophila
-
K.W. Harding, G. Gellon, N. McGinnis, and W. McGinnis A screen for modifiers of Deformed function in Drosophila Genetics 140 1995 1339 1352
-
(1995)
Genetics
, vol.140
, pp. 1339-1352
-
-
Harding, K.W.1
Gellon, G.2
McGinnis, N.3
McGinnis, W.4
-
33
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
D. Harman Aging: a theory based on free radical and radiation chemistry J. Gerontol. 11 1956 298 300
-
(1956)
J. Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
34
-
-
84897421970
-
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
-
J.D. Hayes, and A.T. Dinkova-Kostova The Nrf2 regulatory network provides an interface between redox and intermediary metabolism Trends Biochem. Sci 39 2014 199 218
-
(2014)
Trends Biochem. Sci
, vol.39
, pp. 199-218
-
-
Hayes, J.D.1
Dinkova-Kostova, A.T.2
-
35
-
-
63549121490
-
Nrf2 and Keap1 mutations: Permanent activation of an adaptive response in cancer
-
J.D. Hayes, and M. McMahon Nrf2 and Keap1 mutations: permanent activation of an adaptive response in cancer Trends Biochem. Sci. 34 2009 176 188
-
(2009)
Trends Biochem. Sci.
, vol.34
, pp. 176-188
-
-
Hayes, J.D.1
McMahon, M.2
-
36
-
-
84866774510
-
Ecology: Insecticide resistance after silent spring
-
D.G. Heckel Ecology: insecticide resistance after silent spring Science 337 2012 1612 1614
-
(2012)
Science
, vol.337
, pp. 1612-1614
-
-
Heckel, D.G.1
-
37
-
-
79551610653
-
Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila
-
C.E. Hochmuth, B. Biteau, D. Bohmann, and H. Jasper Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila Cell Stem Cell 8 2011 188 199
-
(2011)
Cell Stem Cell
, vol.8
, pp. 188-199
-
-
Hochmuth, C.E.1
Biteau, B.2
Bohmann, D.3
Jasper, H.4
-
38
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
K. Itoh, N. Wakabayashi, Y. Katoh, T. Ishii, K. Igarashi, J.D. Engel, and M. Yamamoto Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain Genes Dev. 13 1999 76 86
-
(1999)
Genes Dev.
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
39
-
-
84885944468
-
The emerging role of the Nrf2-Keap1 signaling pathway in cancer
-
M.C. Jaramillo, and D.D. Zhang The emerging role of the Nrf2-Keap1 signaling pathway in cancer Genes Dev. 27 2013 2179 2191
-
(2013)
Genes Dev.
, vol.27
, pp. 2179-2191
-
-
Jaramillo, M.C.1
Zhang, D.D.2
-
40
-
-
9944255781
-
Evolutionarily conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome
-
Y. Katoh, K. Iida, M.I. Kang, A. Kobayashi, M. Mizukami, K.I. Tong, M. McMahon, J.D. Hayes, K. Itoh, and M. Yamamoto Evolutionarily conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome Arch. Biochem. Biophys. 433 2005 342 350
-
(2005)
Arch. Biochem. Biophys.
, vol.433
, pp. 342-350
-
-
Katoh, Y.1
Iida, K.2
Kang, M.I.3
Kobayashi, A.4
Mizukami, M.5
Tong, K.I.6
McMahon, M.7
Hayes, J.D.8
Itoh, K.9
Yamamoto, M.10
-
41
-
-
0034752461
-
Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
-
Y. Katoh, K. Itoh, E. Yoshida, M. Miyagishi, A. Fukamizu, and M. Yamamoto Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription Genes Cells 6 2001 857 868
-
(2001)
Genes Cells
, vol.6
, pp. 857-868
-
-
Katoh, Y.1
Itoh, K.2
Yoshida, E.3
Miyagishi, M.4
Fukamizu, A.5
Yamamoto, M.6
-
42
-
-
0033012855
-
Development of cancer chemopreventive agents: Oltipraz as a paradigm
-
T.W. Kensler, J.D. Groopman, T.R. Sutter, T.J. Curphey, and B.D. Roebuck Development of cancer chemopreventive agents: oltipraz as a paradigm Chem. Res. Toxicol. 12 1999 113 126
-
(1999)
Chem. Res. Toxicol.
, vol.12
, pp. 113-126
-
-
Kensler, T.W.1
Groopman, J.D.2
Sutter, T.R.3
Curphey, T.J.4
Roebuck, B.D.5
-
43
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
T.W. Kensler, N. Wakabayashi, and S. Biswal Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway Annu. Rev. Pharmacol. Toxicol. 47 2007 89 116
-
(2007)
Annu. Rev. Pharmacol. Toxicol.
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
44
-
-
80053634368
-
The dynamic nature of autophagy in cancer
-
A.C. Kimmelman The dynamic nature of autophagy in cancer Genes Dev. 25 2011 1999 2010
-
(2011)
Genes Dev.
, vol.25
, pp. 1999-2010
-
-
Kimmelman, A.C.1
-
45
-
-
36349030396
-
Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer
-
M. Kimura, T. Yamamoto, J. Zhang, K. Itoh, M. Kyo, T. Kamiya, H. Aburatani, F. Katsuoka, H. Kurokawa, T. Tanaka, and et al. Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer J. Biol. Chem. 282 2007 33681 33690
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 33681-33690
-
-
Kimura, M.1
Yamamoto, T.2
Zhang, J.3
Itoh, K.4
Kyo, M.5
Kamiya, T.6
Aburatani, H.7
Katsuoka, F.8
Kurokawa, H.9
Tanaka, T.10
-
46
-
-
13944262937
-
Understanding the odd science of aging
-
T.B. Kirkwood Understanding the odd science of aging Cell 120 2005 437 447
-
(2005)
Cell
, vol.120
, pp. 437-447
-
-
Kirkwood, T.B.1
-
47
-
-
0036668466
-
Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system
-
M. Kobayashi, K. Itoh, T. Suzuki, H. Osanai, K. Nishikawa, Y. Katoh, Y. Takagi, and M. Yamamoto Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system Genes Cells 7 2002 807 820
-
(2002)
Genes Cells
, vol.7
, pp. 807-820
-
-
Kobayashi, M.1
Itoh, K.2
Suzuki, T.3
Osanai, H.4
Nishikawa, K.5
Katoh, Y.6
Takagi, Y.7
Yamamoto, M.8
-
48
-
-
77649265091
-
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
-
M. Komatsu, H. Kurokawa, S. Waguri, K. Taguchi, A. Kobayashi, Y. Ichimura, Y.S. Sou, I. Ueno, A. Sakamoto, K.I. Tong, and et al. The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 Nat. Cell Biol. 12 2010 213 223
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 213-223
-
-
Komatsu, M.1
Kurokawa, H.2
Waguri, S.3
Taguchi, K.4
Kobayashi, A.5
Ichimura, Y.6
Sou, Y.S.7
Ueno, I.8
Sakamoto, A.9
Tong, K.I.10
-
49
-
-
84901438884
-
Redox regulation by Pitx2 and Pitx3 is critical for fetal myogenesis
-
A. L'Honore, P.H. Commere, J.F. Ouimette, D. Montarras, J. Drouin, and M. Buckingham Redox regulation by Pitx2 and Pitx3 is critical for fetal myogenesis Dev. Cell 29 2014 392 405
-
(2014)
Dev. Cell
, vol.29
, pp. 392-405
-
-
L'Honore, A.1
Commere, P.H.2
Ouimette, J.F.3
Montarras, D.4
Drouin, J.5
Buckingham, M.6
-
50
-
-
0020520516
-
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
-
H. Land, L.F. Parada, and R.A. Weinberg Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes Nature 304 1983 596 602
-
(1983)
Nature
, vol.304
, pp. 596-602
-
-
Land, H.1
Parada, L.F.2
Weinberg, R.A.3
-
51
-
-
84904251656
-
Comparison of D. Melanogaster and C. Elegans developmental stages, tissues, and cells by modENCODE RNA-seq data
-
J.J. Li, H. Huang, P.J. Bickel, and S.E. Brenner Comparison of D. melanogaster and C. elegans developmental stages, tissues, and cells by modENCODE RNA-seq data Genome Res. 24 2014 1086 1101
-
(2014)
Genome Res.
, vol.24
, pp. 1086-1101
-
-
Li, J.J.1
Huang, H.2
Bickel, P.J.3
Brenner, S.E.4
-
52
-
-
79952136166
-
Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
-
R.A. Linker, D.H. Lee, S. Ryan, A.M. van Dam, R. Conrad, P. Bista, W. Zeng, X. Hronowsky, A. Buko, S. Chollate, and et al. Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway Brain 134 2011 678 692
-
(2011)
Brain
, vol.134
, pp. 678-692
-
-
Linker, R.A.1
Lee, D.H.2
Ryan, S.3
Van Dam, A.M.4
Conrad, R.5
Bista, P.6
Zeng, W.7
Hronowsky, X.8
Buko, A.9
Chollate, S.10
-
53
-
-
84878864199
-
The hallmarks of aging
-
C. Lopez-Otin, M.A. Blasco, L. Partridge, M. Serrano, and G. Kroemer The hallmarks of aging Cell 153 2013 1194 1217
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
Lopez-Otin, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
54
-
-
61449182121
-
Principles of cancer therapy: Oncogene and non-oncogene addiction
-
J. Luo, N.L. Solimini, and S.J. Elledge Principles of cancer therapy: oncogene and non-oncogene addiction Cell 136 2009 823 837
-
(2009)
Cell
, vol.136
, pp. 823-837
-
-
Luo, J.1
Solimini, N.L.2
Elledge, S.J.3
-
55
-
-
0034595389
-
Factors on the third chromosome affect the level of cyp6a2 and cyp6a8 expression in Drosophila melanogaster
-
S. Maitra, S.M. Dombrowski, M. Basu, O. Raustol, L.C. Waters, and R. Ganguly Factors on the third chromosome affect the level of cyp6a2 and cyp6a8 expression in Drosophila melanogaster Gene 248 2000 147 156
-
(2000)
Gene
, vol.248
, pp. 147-156
-
-
Maitra, S.1
Dombrowski, S.M.2
Basu, M.3
Raustol, O.4
Waters, L.C.5
Ganguly, R.6
-
56
-
-
0031646521
-
A cap 'n' collar protein isoform contains a selective Hox repressor function
-
N. McGinnis, E. Ragnhildstveit, A. Veraksa, and W. McGinnis A cap 'n' collar protein isoform contains a selective Hox repressor function Development 125 1998 4553 4564
-
(1998)
Development
, vol.125
, pp. 4553-4564
-
-
McGinnis, N.1
Ragnhildstveit, E.2
Veraksa, A.3
McGinnis, W.4
-
57
-
-
33747728194
-
Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: A two-site interaction model for the Nrf2-Keap1 complex
-
M. McMahon, N. Thomas, K. Itoh, M. Yamamoto, and J.D. Hayes Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex J. Biol. Chem 281 2006 24756 24768
-
(2006)
J. Biol. Chem
, vol.281
, pp. 24756-24768
-
-
McMahon, M.1
Thomas, N.2
Itoh, K.3
Yamamoto, M.4
Hayes, J.D.5
-
59
-
-
84883577718
-
Analysis tool Web services from the EMBL-EBI
-
H. McWilliam, W. Li, M. Uludag, S. Squizzato, Y.M. Park, N. Buso, A.P. Cowley, and R. Lopez Analysis tool Web services from the EMBL-EBI Nucleic Acids Res. 41 2013 W597 W600
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. W597-W600
-
-
McWilliam, H.1
Li, W.2
Uludag, M.3
Squizzato, S.4
Park, Y.M.5
Buso, N.6
Cowley, A.P.7
Lopez, R.8
-
60
-
-
80052452088
-
Transcriptional regulation of xenobiotic detoxification in Drosophila
-
J.R. Misra, M.A. Horner, G. Lam, and C.S. Thummel Transcriptional regulation of xenobiotic detoxification in Drosophila Genes Dev. 25 2011 1796 1806
-
(2011)
Genes Dev.
, vol.25
, pp. 1796-1806
-
-
Misra, J.R.1
Horner, M.A.2
Lam, G.3
Thummel, C.S.4
-
61
-
-
84885990241
-
Constitutive activation of the Nrf2/Keap1 pathway in insecticide-resistant strains of Drosophila
-
J.R. Misra, G. Lam, and C.S. Thummel Constitutive activation of the Nrf2/Keap1 pathway in insecticide-resistant strains of Drosophila Insect Biochem. Mol. Biol. 43 2013 1116 1124
-
(2013)
Insect Biochem. Mol. Biol.
, vol.43
, pp. 1116-1124
-
-
Misra, J.R.1
Lam, G.2
Thummel, C.S.3
-
62
-
-
36249025723
-
Autophagy: Process and function
-
N. Mizushima Autophagy: process and function Genes Dev. 21 2007 2861 2873
-
(2007)
Genes Dev.
, vol.21
, pp. 2861-2873
-
-
Mizushima, N.1
-
63
-
-
81055144784
-
Autophagy: Renovation of cells and tissues
-
N. Mizushima, and M. Komatsu Autophagy: renovation of cells and tissues Cell 147 2011 728 741
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
64
-
-
78650331647
-
Identification of functional elements and regulatory circuits by Drosophila modENCODE
-
modENCODE Consortium, S. Roy, J. Ernst, P.V. Kharchenko, P. Kheradpour, N. Negre, M.L. Eaton, J.M. Landolin, C.A. Bristow, L. Ma, and et al. Identification of functional elements and regulatory circuits by Drosophila modENCODE Science 330 2010 1787 1797
-
(2010)
Science
, vol.330
, pp. 1787-1797
-
-
Consortium, M.1
Roy, S.2
Ernst, J.3
Kharchenko, P.V.4
Kheradpour, P.5
Negre, N.6
Eaton, M.L.7
Landolin, J.M.8
Bristow, C.A.9
Ma, L.10
-
65
-
-
0028795364
-
Control of Drosophila head segment identity by the bZIP homeotic gene cnc
-
J. Mohler, J.W. Mahaffey, E. Deutsch, and K. Vani Control of Drosophila head segment identity by the bZIP homeotic gene cnc Development 121 1995 237 247
-
(1995)
Development
, vol.121
, pp. 237-247
-
-
Mohler, J.1
Mahaffey, J.W.2
Deutsch, E.3
Vani, K.4
-
66
-
-
0025868833
-
Segmentally restricted, cephalic expression of a leucine zipper gene during Drosophila embryogenesis
-
J. Mohler, K. Vani, S. Leung, and A. Epstein Segmentally restricted, cephalic expression of a leucine zipper gene during Drosophila embryogenesis Mech. Dev. 34 1991 3 9
-
(1991)
Mech. Dev.
, vol.34
, pp. 3-9
-
-
Mohler, J.1
Vani, K.2
Leung, S.3
Epstein, A.4
-
67
-
-
84901364818
-
Resources for functional genomics studies in Drosophila melanogaster
-
S.E. Mohr, Y. Hu, K. Kim, B.E. Housden, and N. Perrimon Resources for functional genomics studies in Drosophila melanogaster Genetics 197 2014 1 18
-
(2014)
Genetics
, vol.197
, pp. 1-18
-
-
Mohr, S.E.1
Hu, Y.2
Kim, K.3
Housden, B.E.4
Perrimon, N.5
-
68
-
-
0027163005
-
Evolution of Drosophila insecticide resistance
-
R.A. Morton Evolution of Drosophila insecticide resistance Genome 36 1993 1 7
-
(1993)
Genome
, vol.36
, pp. 1-7
-
-
Morton, R.A.1
-
69
-
-
84897980875
-
Genetics and epigenetics of aging and longevity
-
A.A. Moskalev, A.M. Aliper, Z. Smit-McBride, A. Buzdin, and A. Zhavoronkov Genetics and epigenetics of aging and longevity Cell Cycle 13 2014 1063 1077
-
(2014)
Cell Cycle
, vol.13
, pp. 1063-1077
-
-
Moskalev, A.A.1
Aliper, A.M.2
Smit-McBride, Z.3
Buzdin, A.4
Zhavoronkov, A.5
-
70
-
-
2342511435
-
Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway
-
H. Motohashi, F. Katsuoka, J.D. Engel, and M. Yamamoto Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway Proc. Natl. Acad. Sci. USA 101 2004 6379 6384
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 6379-6384
-
-
Motohashi, H.1
Katsuoka, F.2
Engel, J.D.3
Yamamoto, M.4
-
71
-
-
0030791154
-
The world according to Maf
-
H. Motohashi, J.A. Shavit, K. Igarashi, M. Yamamoto, and J.D. Engel The world according to Maf Nucleic Acids Res. 25 1997 2953 2959
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 2953-2959
-
-
Motohashi, H.1
Shavit, J.A.2
Igarashi, K.3
Yamamoto, M.4
Engel, J.D.5
-
72
-
-
84908108248
-
Widespread pyrethroid and DDT resistance in the major malaria vector Anopheles funestus in East Africa is driven by metabolic resistance mechanisms
-
C. Mulamba, J.M. Riveron, S.S. Ibrahim, H. Irving, K.G. Barnes, L.G. Mukwaya, J. Birungi, and C.S. Wondji Widespread pyrethroid and DDT resistance in the major malaria vector Anopheles funestus in East Africa is driven by metabolic resistance mechanisms PLoS One 9 2014 e110058
-
(2014)
PLoS One
, vol.9
, pp. e110058
-
-
Mulamba, C.1
Riveron, J.M.2
Ibrahim, S.S.3
Irving, H.4
Barnes, K.G.5
Mukwaya, L.G.6
Birungi, J.7
Wondji, C.S.8
-
73
-
-
84884636654
-
Myc-driven overgrowth requires unfolded protein response-mediated induction of autophagy and antioxidant responses in Drosophila melanogaster
-
P. Nagy, A. Varga, K. Pircs, K. Hegedus, and G. Juhasz Myc-driven overgrowth requires unfolded protein response-mediated induction of autophagy and antioxidant responses in Drosophila melanogaster PLoS Genet. 9 2013 e1003664
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003664
-
-
Nagy, P.1
Varga, A.2
Pircs, K.3
Hegedus, K.4
Juhasz, G.5
-
74
-
-
41549151641
-
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
-
I.P. Nezis, A. Simonsen, A.P. Sagona, K. Finley, S. Gaumer, D. Contamine, T.E. Rusten, H. Stenmark, and A. Brech Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain J. Cell Biol. 180 2008 1065 1071
-
(2008)
J. Cell Biol.
, vol.180
, pp. 1065-1071
-
-
Nezis, I.P.1
Simonsen, A.2
Sagona, A.P.3
Finley, K.4
Gaumer, S.5
Contamine, D.6
Rusten, T.E.7
Stenmark, H.8
Brech, A.9
-
75
-
-
0042330074
-
Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: Reassessment of the ARE consensus sequence
-
P. Nioi, M. McMahon, K. Itoh, M. Yamamoto, and J.D. Hayes Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence Biochem. J. 374 2003 337 348
-
(2003)
Biochem. J.
, vol.374
, pp. 337-348
-
-
Nioi, P.1
McMahon, M.2
Itoh, K.3
Yamamoto, M.4
Hayes, J.D.5
-
76
-
-
28544450507
-
The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation
-
P. Nioi, T. Nguyen, P.J. Sherratt, and C.B. Pickett The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation Mol. Cell. Biol. 25 2005 10895 10906
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 10895-10906
-
-
Nioi, P.1
Nguyen, T.2
Sherratt, P.J.3
Pickett, C.B.4
-
77
-
-
84922324310
-
Autocrine regulation of ecdysone synthesis by beta3-octopamine receptor in the prothoracic gland is essential for Drosophila metamorphosis
-
Y. Ohhara, Y. Shimada-Niwa, R. Niwa, Y. Kayashima, Y. Hayashi, K. Akagi, H. Ueda, K. Yamakawa-Kobayashi, and S. Kobayashi Autocrine regulation of ecdysone synthesis by beta3-octopamine receptor in the prothoracic gland is essential for Drosophila metamorphosis Proc. Natl. Acad. Sci. USA 112 2015 1452 1457
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. 1452-1457
-
-
Ohhara, Y.1
Shimada-Niwa, Y.2
Niwa, R.3
Kayashima, Y.4
Hayashi, Y.5
Akagi, K.6
Ueda, H.7
Yamakawa-Kobayashi, K.8
Kobayashi, S.9
-
78
-
-
57749120460
-
Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes
-
M. Ohtsuji, F. Katsuoka, A. Kobayashi, H. Aburatani, J.D. Hayes, and M. Yamamoto Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes J. Biol. Chem. 283 2008 33554 33562
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 33554-33562
-
-
Ohtsuji, M.1
Katsuoka, F.2
Kobayashi, A.3
Aburatani, H.4
Hayes, J.D.5
Yamamoto, M.6
-
79
-
-
47849083585
-
Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults
-
W.O. Osburn, and T.W. Kensler Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults Mutat. Res 659 2008 31 39
-
(2008)
Mutat. Res
, vol.659
, pp. 31-39
-
-
Osburn, W.O.1
Kensler, T.W.2
-
80
-
-
84858972249
-
Nrf2-dependent induction of proteasome and Pa28alphabeta regulator are required for adaptation to oxidative stress
-
A.M. Pickering, R.A. Linder, H. Zhang, H.J. Forman, and K.J. Davies Nrf2-dependent induction of proteasome and Pa28alphabeta regulator are required for adaptation to oxidative stress J. Biol. Chem. 287 2012 10021 10031
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 10021-10031
-
-
Pickering, A.M.1
Linder, R.A.2
Zhang, H.3
Forman, H.J.4
Davies, K.J.5
-
81
-
-
84865623676
-
Advantages and limitations of different p62-based assays for estimating autophagic activity in Drosophila
-
K. Pircs, P. Nagy, A. Varga, Z. Venkei, B. Erdi, K. Hegedus, and G. Juhasz Advantages and limitations of different p62-based assays for estimating autophagic activity in Drosophila PLoS One 7 2012 e44214
-
(2012)
PLoS One
, vol.7
, pp. e44214
-
-
Pircs, K.1
Nagy, P.2
Varga, A.3
Venkei, Z.4
Erdi, B.5
Hegedus, K.6
Juhasz, G.7
-
82
-
-
0030661627
-
Point mutations in the Drosophila sodium channel gene para associated with resistance to DDT and pyrethroid insecticides
-
B. Pittendrigh, R. Reenan, R.H. ffrench-Constant, and B. Ganetzky Point mutations in the Drosophila sodium channel gene para associated with resistance to DDT and pyrethroid insecticides Mol. Gen. Genet. 256 1997 602 610
-
(1997)
Mol. Gen. Genet.
, vol.256
, pp. 602-610
-
-
Pittendrigh, B.1
Reenan, R.2
Ffrench-Constant, R.H.3
Ganetzky, B.4
-
83
-
-
79952256187
-
SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner
-
P. Rada, A.I. Rojo, S. Chowdhry, M. McMahon, J.D. Hayes, and A. Cuadrado SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner Mol. Cell. Biol. 31 2011 1121 1133
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 1121-1133
-
-
Rada, P.1
Rojo, A.I.2
Chowdhry, S.3
McMahon, M.4
Hayes, J.D.5
Cuadrado, A.6
-
84
-
-
77950366349
-
Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells
-
S.K. Radhakrishnan, C.S. Lee, P. Young, A. Beskow, J.Y. Chan, and R.J. Deshaies Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells Mol. Cell 38 2010 17 28
-
(2010)
Mol. Cell
, vol.38
, pp. 17-28
-
-
Radhakrishnan, S.K.1
Lee, C.S.2
Young, P.3
Beskow, A.4
Chan, J.Y.5
Deshaies, R.J.6
-
85
-
-
84880514122
-
Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes
-
M.M. Rahman, G.P. Sykiotis, M. Nishimura, R. Bodmer, and D. Bohmann Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes Aging Cell. 2013
-
(2013)
Aging Cell.
-
-
Rahman, M.M.1
Sykiotis, G.P.2
Nishimura, M.3
Bodmer, R.4
Bohmann, D.5
-
86
-
-
33750729203
-
Theories of biological aging: Genes, proteins, and free radicals
-
S.I. Rattan Theories of biological aging: genes, proteins, and free radicals Free Radic. Res. 40 2006 1230 1238
-
(2006)
Free Radic. Res.
, vol.40
, pp. 1230-1238
-
-
Rattan, S.I.1
-
87
-
-
71549168637
-
The insect neuropeptide PTTH activates receptor tyrosine kinase torso to initiate metamorphosis
-
K.F. Rewitz, N. Yamanaka, L.I. Gilbert, and M.B. O'Connor The insect neuropeptide PTTH activates receptor tyrosine kinase torso to initiate metamorphosis Science 326 2009 1403 1405
-
(2009)
Science
, vol.326
, pp. 1403-1405
-
-
Rewitz, K.F.1
Yamanaka, N.2
Gilbert, L.I.3
O'Connor, M.B.4
-
88
-
-
0025322840
-
Putative protein kinase product of the Drosophila segment-polarity gene zeste-white3
-
E. Siegfried, L.A. Perkins, T.M. Capaci, and N. Perrimon Putative protein kinase product of the Drosophila segment-polarity gene zeste-white3 Nature 345 1990 825 829
-
(1990)
Nature
, vol.345
, pp. 825-829
-
-
Siegfried, E.1
Perkins, L.A.2
Capaci, T.M.3
Perrimon, N.4
-
89
-
-
0033083158
-
Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP
-
E. Spencer, J. Jiang, and Z.J. Chen Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP Genes Dev. 13 1999 284 294
-
(1999)
Genes Dev.
, vol.13
, pp. 284-294
-
-
Spencer, E.1
Jiang, J.2
Chen, Z.J.3
-
90
-
-
37749024370
-
Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila
-
G.P. Sykiotis, and D. Bohmann Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila Dev. Cell 14 2008 76 85
-
(2008)
Dev. Cell
, vol.14
, pp. 76-85
-
-
Sykiotis, G.P.1
Bohmann, D.2
-
91
-
-
77953012548
-
Stress-activated Cap'n'collar transcription factors in aging and human disease
-
re3
-
G.P. Sykiotis, and D. Bohmann Stress-activated Cap'n'collar transcription factors in aging and human disease Sci. Signaling 3 2010 re3
-
(2010)
Sci. Signaling
, vol.3
-
-
Sykiotis, G.P.1
Bohmann, D.2
-
92
-
-
84899671764
-
Lysosomal function is involved in 17beta-estradiol-induced estrogen receptor alpha degradation and cell proliferation
-
P. Totta, V. Pesiri, M. Marino, and F. Acconcia Lysosomal function is involved in 17beta-estradiol-induced estrogen receptor alpha degradation and cell proliferation PLoS One 9 2014 e94880
-
(2014)
PLoS One
, vol.9
, pp. e94880
-
-
Totta, P.1
Pesiri, V.2
Marino, M.3
Acconcia, F.4
-
93
-
-
77951543964
-
Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an Nrf2-dependent mechanism
-
K. Trinh, L. Andrews, J. Krause, T. Hanak, D. Lee, M. Gelb, and L. Pallanck Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an Nrf2-dependent mechanism J. Neurosci. 30 2010 5525 5532
-
(2010)
J. Neurosci.
, vol.30
, pp. 5525-5532
-
-
Trinh, K.1
Andrews, L.2
Krause, J.3
Hanak, T.4
Lee, D.5
Gelb, M.6
Pallanck, L.7
-
94
-
-
84874655208
-
Nrf2 regulates haematopoietic stem cell function
-
J.J. Tsai, J.A. Dudakov, K. Takahashi, J.H. Shieh, E. Velardi, A.M. Holland, N.V. Singer, M.L. West, O.M. Smith, L.F. Young, and et al. Nrf2 regulates haematopoietic stem cell function Nat. Cell Biol. 15 2013 309 316
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 309-316
-
-
Tsai, J.J.1
Dudakov, J.A.2
Takahashi, K.3
Shieh, J.H.4
Velardi, E.5
Holland, A.M.6
Singer, N.V.7
West, M.L.8
Smith, O.M.9
Young, L.F.10
-
95
-
-
84878764019
-
Differential regulation of proteasome functionality in reproductive vs. Somatic tissues of Drosophila during aging or oxidative stress
-
E.N. Tsakiri, G.P. Sykiotis, I.S. Papassideri, V.G. Gorgoulis, D. Bohmann, and I.P. Trougakos Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress FASEB J. 27 2013 2407 2420
-
(2013)
FASEB J.
, vol.27
, pp. 2407-2420
-
-
Tsakiri, E.N.1
Sykiotis, G.P.2
Papassideri, I.S.3
Gorgoulis, V.G.4
Bohmann, D.5
Trougakos, I.P.6
-
96
-
-
84883750565
-
Proteasome dysfunction in Drosophila signals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging
-
E.N. Tsakiri, G.P. Sykiotis, I.S. Papassideri, E. Terpos, M.A. Dimopoulos, V.G. Gorgoulis, D. Bohmann, and I.P. Trougakos Proteasome dysfunction in Drosophila signals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging Aging Cell 12 2013 802 813
-
(2013)
Aging Cell
, vol.12
, pp. 802-813
-
-
Tsakiri, E.N.1
Sykiotis, G.P.2
Papassideri, I.S.3
Terpos, E.4
Dimopoulos, M.A.5
Gorgoulis, V.G.6
Bohmann, D.7
Trougakos, I.P.8
-
97
-
-
40849118472
-
Direct inhibition of the longevity promoting factor SKN-1 by insulinlike signaling in C. Elegans
-
J.M.A. Tullet, M. Hertweck, J.H. An, J. Baker, R.P. Oliviera, R. Baumeister, and T.K. Blackwell Direct inhibition of the longevity promoting factor SKN-1 by insulinlike signaling in C. elegans Cell 2008 132
-
(2008)
Cell
, pp. 132
-
-
Tullet, J.M.A.1
Hertweck, M.2
An, J.H.3
Baker, J.4
Oliviera, R.P.5
Baumeister, R.6
Blackwell, T.K.7
-
98
-
-
0033792944
-
Cap 'n' collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress deformed homeotic function in the Drosophila head
-
A. Veraksa, N. McGinnis, X. Li, J. Mohler, and W. McGinnis Cap 'n' collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress deformed homeotic function in the Drosophila head Development 127 2000 4023 4037
-
(2000)
Development
, vol.127
, pp. 4023-4037
-
-
Veraksa, A.1
McGinnis, N.2
Li, X.3
Mohler, J.4
McGinnis, W.5
-
99
-
-
0242329881
-
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
-
N. Wakabayashi, K. Itoh, J. Wakabayashi, H. Motohashi, S. Noda, S. Takahashi, S. Imakado, T. Kotsuji, F. Otsuka, D.R. Roop, and et al. Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation Nat. Genet. 35 2003 238 245
-
(2003)
Nat. Genet.
, vol.35
, pp. 238-245
-
-
Wakabayashi, N.1
Itoh, K.2
Wakabayashi, J.3
Motohashi, H.4
Noda, S.5
Takahashi, S.6
Imakado, S.7
Kotsuji, T.8
Otsuka, F.9
Roop, D.R.10
-
100
-
-
33745807575
-
Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain: Inhibition of nuclear translocation and transacting function
-
W. Wang, and J.Y. Chan Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain: inhibition of nuclear translocation and transacting function J. Biol. Chem 281 2006 19676 19687
-
(2006)
J. Biol. Chem
, vol.281
, pp. 19676-19687
-
-
Wang, W.1
Chan, J.Y.2
-
101
-
-
84928796551
-
Mitochondrial reactive oxygen species regulate adipocyte differentiation of mesenchymal stem cells in hematopoietic stress induced by arabinosylcytosine
-
W. Wang, Y. Zhang, W. Lu, and K. Liu Mitochondrial reactive oxygen species regulate adipocyte differentiation of mesenchymal stem cells in hematopoietic stress induced by arabinosylcytosine PLoS One 10 2015 e0120629
-
(2015)
PLoS One
, vol.10
, pp. e0120629
-
-
Wang, W.1
Zhang, Y.2
Lu, W.3
Liu, K.4
-
102
-
-
77957821749
-
Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer
-
X. Wang, B.N. Chorley, G.S. Pittman, S.R. Kleeberger, J. Brothers 2nd, G. Liu, A. Spira, and D.A. Bell Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer PLoS One 5 2010 e11934
-
(2010)
PLoS One
, vol.5
, pp. e11934
-
-
Wang, X.1
Chorley, B.N.2
Pittman, G.S.3
Kleeberger, S.R.4
Brothers, J.5
Liu, G.6
Spira, A.7
Bell, D.A.8
-
103
-
-
84861526009
-
Deconvoluting the context-dependent role for autophagy in cancer
-
E. White Deconvoluting the context-dependent role for autophagy in cancer Nat. Rev. Cancer 12 2012 401 410
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 401-410
-
-
White, E.1
-
104
-
-
0242580049
-
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
-
D.D. Zhang, and M. Hannink Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress Mol. Cell. Biol. 23 2003 8137 8151
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8137-8151
-
-
Zhang, D.D.1
Hannink, M.2
-
105
-
-
10044228504
-
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex
-
D.D. Zhang, S.C. Lo, J.V. Cross, D.J. Templeton, and M. Hannink Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex Mol. Cell. Biol. 24 2004 10941 10953
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 10941-10953
-
-
Zhang, D.D.1
Lo, S.C.2
Cross, J.V.3
Templeton, D.J.4
Hannink, M.5
-
106
-
-
33750543308
-
Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum
-
Y. Zhang, D.H. Crouch, M. Yamamoto, and J.D. Hayes Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum Biochem. J 399 2006 373 385
-
(2006)
Biochem. J
, vol.399
, pp. 373-385
-
-
Zhang, Y.1
Crouch, D.H.2
Yamamoto, M.3
Hayes, J.D.4
-
107
-
-
4444315787
-
A strategy for cancer prevention: Stimulation of the Nrf2-ARE signaling pathway
-
Y. Zhang, and G.B. Gordon A strategy for cancer prevention: stimulation of the Nrf2-ARE signaling pathway Mol. Cancer Ther. 3 2004 885 893
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 885-893
-
-
Zhang, Y.1
Gordon, G.B.2
-
108
-
-
36749013169
-
The NHB1 (N-terminal homology box 1) sequence in transcription factor Nrf1 is required to anchor it to the endoplasmic reticulum and also to enable its asparagine-glycosylation
-
Y. Zhang, J.M. Lucocq, M. Yamamoto, and J.D. Hayes The NHB1 (N-terminal homology box 1) sequence in transcription factor Nrf1 is required to anchor it to the endoplasmic reticulum and also to enable its asparagine-glycosylation Biochem. J. 408 2007 161 172
-
(2007)
Biochem. J.
, vol.408
, pp. 161-172
-
-
Zhang, Y.1
Lucocq, J.M.2
Yamamoto, M.3
Hayes, J.D.4
-
109
-
-
84906898355
-
Coordinated regulation of protein synthesis and degradation by mTORC1
-
Y. Zhang, J. Nicholatos, J.R. Dreier, S.J. Ricoult, S.B. Widenmaier, G.S. Hotamisligil, D.J. Kwiatkowski, and B.D. Manning Coordinated regulation of protein synthesis and degradation by mTORC1 Nature 513 2014 440 443
-
(2014)
Nature
, vol.513
, pp. 440-443
-
-
Zhang, Y.1
Nicholatos, J.2
Dreier, J.R.3
Ricoult, S.J.4
Widenmaier, S.B.5
Hotamisligil, G.S.6
Kwiatkowski, D.J.7
Manning, B.D.8
-
110
-
-
84898850319
-
Transcription factor Nrf1 is topologically repartitioned across membranes to enable target gene transactivation through its acidic glucose-responsive domains
-
Y. Zhang, Y. Ren, S. Li, and J.D. Hayes Transcription factor Nrf1 is topologically repartitioned across membranes to enable target gene transactivation through its acidic glucose-responsive domains PLoS One 9 2014 e93458
-
(2014)
PLoS One
, vol.9
, pp. e93458
-
-
Zhang, Y.1
Ren, Y.2
Li, S.3
Hayes, J.D.4
-
111
-
-
84922627875
-
Mitochondrial effectors of cellular senescence: Beyond the free radical theory of aging
-
D.V. Ziegler, C.D. Wiley, and M.C. Velarde Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging Aging Cell 14 2015 1 7
-
(2015)
Aging Cell
, vol.14
, pp. 1-7
-
-
Ziegler, D.V.1
Wiley, C.D.2
Velarde, M.C.3
|