-
1
-
-
79960835354
-
Participation of covalent modification of Keap1 in the activation of Nrf2 by tertbutylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole
-
Abiko, Y., Miura, T., Phuc, B. H., Shinkai, Y. and Kumagai, Y. (2011). Participation of covalent modification of Keap1 in the activation of Nrf2 by tertbutylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole. Toxicol. Appl. Pharmacol. 255, 32-39.
-
(2011)
Toxicol. Appl. Pharmacol.
, vol.255
, pp. 32-39
-
-
Abiko, Y.1
Miura, T.2
Phuc, B.H.3
Shinkai, Y.4
Kumagai, Y.5
-
2
-
-
0030030902
-
The eve stripe 2 enhancer employs multiple modes of transcriptional synergy
-
Arnosti, D. N., Barolo, S., Levine, M. and Small, S. (1996). The eve stripe 2 enhancer employs multiple modes of transcriptional synergy. Development 122, 205-214.
-
(1996)
Development
, vol.122
, pp. 205-214
-
-
Arnosti, D.N.1
Barolo, S.2
Levine, M.3
Small, S.4
-
3
-
-
79960353615
-
Opposing roles of FoxP1 and Nfat3 in transcriptional control of cardiomyocyte hypertrophy
-
Bai, S. and Kerppola, T. K. (2011). Opposing roles of FoxP1 and Nfat3 in transcriptional control of cardiomyocyte hypertrophy. Mol. Cell. Biol. 31, 3068-3080.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 3068-3080
-
-
Bai, S.1
Kerppola, T.K.2
-
4
-
-
84901585344
-
Drosophila melanogaster Hox transcription factors access the RNA polymerase II machinery through direct homeodomain binding to a conserved motif of mediator subunit Med19
-
Boube, M., Hudry, B., Immarigeon, C., Carrier, Y., Bernat-Fabre, S., Merabet, S., Graba, Y., Bourbon, H.-M. and Cribbs, D. L. (2014). Drosophila melanogaster Hox transcription factors access the RNA polymerase II machinery through direct homeodomain binding to a conserved motif of mediator subunit Med19. PLoS Genet. 10, e1004303.
-
(2014)
PLoS Genet.
, vol.10
-
-
Boube, M.1
Hudry, B.2
Immarigeon, C.3
Carrier, Y.4
Bernat-Fabre, S.5
Merabet, S.6
Graba, Y.7
Bourbon, H.-M.8
Cribbs, D.L.9
-
5
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generatingdominant phenotypes
-
Brand, A. H. and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generatingdominant phenotypes. Development 118, 401-415.
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
6
-
-
84866398522
-
Opposite orientations of a transcription factor heterodimer bind DNA cooperatively with interaction partners but have different effects on interferon-β gene transcription
-
Burns, V. and Kerppola, T. K. (2012). Opposite orientations of a transcription factor heterodimer bind DNA cooperatively with interaction partners but have different effects on interferon-β gene transcription. J. Biol. Chem. 287, 31833-31844.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 31833-31844
-
-
Burns, V.1
Kerppola, T.K.2
-
7
-
-
0037262925
-
EcR isoforms in Drosophila: Testing tissue-specific requirements by targeted blockade and rescue
-
Cherbas, L., Hu, X., Zhimulev, I., Belyaeva, E. and Cherbas, P. (2003). EcR isoforms in Drosophila: testing tissue-specific requirements by targeted blockade and rescue. Development 130, 271-284.
-
(2003)
Development
, vol.130
, pp. 271-284
-
-
Cherbas, L.1
Hu, X.2
Zhimulev, I.3
Belyaeva, E.4
Cherbas, P.5
-
8
-
-
84874764624
-
Regulation of Drosophila metamorphosis by xenobiotic response regulators
-
Deng, H. and Kerppola, T. K. (2013). Regulation of Drosophila metamorphosis by xenobiotic response regulators. PLoS Genet. 9, e1003263.
-
(2013)
PLoS Genet.
, vol.9
-
-
Deng, H.1
Kerppola, T.K.2
-
9
-
-
11144343726
-
Hormonal cross talk in insect development
-
Dubrovsky, E. B. (2005). Hormonal cross talk in insect development. Trends Endocrinol. Metab. 16, 6-11.
-
(2005)
Trends Endocrinol. Metab.
, vol.16
, pp. 6-11
-
-
Dubrovsky, E.B.1
-
10
-
-
22544464124
-
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2
-
Eggler, A. L., Liu, G., Pezzuto, J. M., van Breemen, R. B. and Mesecar, A. D. (2005). Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. Proc. Natl. Acad. Sci. USA 102, 10070-10075.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 10070-10075
-
-
Eggler, A.L.1
Liu, G.2
Pezzuto, J.M.3
van Breemen, R.B.4
Mesecar, A.D.5
-
11
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
ENCODE Project Consortium
-
ENCODE Project Consortium, Bernstein, B. E., Birney, E., Dunham, I., Green, E. D., Gunter, C. and Snyder, M. (2012). An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Bernstein, B.E.1
Birney, E.2
Dunham, I.3
Green, E.D.4
Gunter, C.5
Snyder, M.6
-
12
-
-
78650051609
-
WAVE forms hetero-and homo-oligomeric complexes at integrin junctions in Drosophila visualized by bimolecular fluorescence complementation
-
Gohl, C., Banovic, D., Grevelhorster, A. and Bogdan, S. (2010). WAVE forms hetero-and homo-oligomeric complexes at integrin junctions in Drosophila visualized by bimolecular fluorescence complementation. J. Biol. Chem. 285, 40171-40179.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 40171-40179
-
-
Gohl, C.1
Banovic, D.2
Grevelhorster, A.3
Bogdan, S.4
-
13
-
-
0036241055
-
Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation
-
Hu, C.-D., Chinenov, Y. and Kerppola, T. K. (2002). Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation. Mol. Cell 9, 789-798.
-
(2002)
Mol. Cell
, vol.9
, pp. 789-798
-
-
Hu, C.-D.1
Chinenov, Y.2
Kerppola, T.K.3
-
14
-
-
33746889956
-
Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice
-
Hu, R., Xu, C., Shen, G., Jain, M. R., Khor, T. O., Gopalkrishnan, A., Lin, W., Reddy, B., Chan, J. Y. and Kong, A. N. (2006). Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice. Cancer Lett. 243, 170-192.
-
(2006)
Cancer Lett.
, vol.243
, pp. 170-192
-
-
Hu, R.1
Xu, C.2
Shen, G.3
Jain, M.R.4
Khor, T.O.5
Gopalkrishnan, A.6
Lin, W.7
Reddy, B.8
Chan, J.Y.9
Kong, A.N.10
-
15
-
-
79251552527
-
Visualization of protein interactions in living Drosophila embryos by the bimolecular fluorescence complementation assay
-
Hudry, B., Viala, S., Graba, Y. and Merabet, S. (2011). Visualization of protein interactions in living Drosophila embryos by the bimolecular fluorescence complementation assay. BMC Biol. 9, 5.
-
(2011)
BMC Biol.
, vol.9
, pp. 5
-
-
Hudry, B.1
Viala, S.2
Graba, Y.3
Merabet, S.4
-
16
-
-
78649320759
-
Tert-butylhydroquinone induces mitochondrial oxidative stress causing Nrf2 activation
-
Imhoff, B. R. and Hansen, J. M. (2010). Tert-butylhydroquinone induces mitochondrial oxidative stress causing Nrf2 activation. Cell Biol. Toxicol. 26, 541-551.
-
(2010)
Cell Biol. Toxicol.
, vol.26
, pp. 541-551
-
-
Imhoff, B.R.1
Hansen, J.M.2
-
17
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh, K., Wakabayashi, N., Katoh, Y., Ishii, T., Igarashi, K., Engel, J. D. and Yamamoto, M. (1999). Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 13, 76-86.
-
(1999)
Genes Dev.
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
18
-
-
84872335543
-
An overview of transcriptional regulation in response to toxicological insult
-
Jennings, P., Limonciel, A., Felice, L. and Leonard, M. O. (2013). An overview of transcriptional regulation in response to toxicological insult. Arch. Toxicol. 87, 49-72.
-
(2013)
Arch. Toxicol.
, vol.87
, pp. 49-72
-
-
Jennings, P.1
Limonciel, A.2
Felice, L.3
Leonard, M.O.4
-
19
-
-
67849109989
-
Polytene chromosome squash methods for studying transcription and epigenetic chromatin modification in Drosophila using antibodies
-
Johansen, K. M., Cai, W., Deng, H., Bao, X., Zhang, W., Girton, J. and Johansen, J. (2009). Polytene chromosome squash methods for studying transcription and epigenetic chromatin modification in Drosophila using antibodies. Methods 48, 387-397.
-
(2009)
Methods
, vol.48
, pp. 387-397
-
-
Johansen, K.M.1
Cai, W.2
Deng, H.3
Bao, X.4
Zhang, W.5
Girton, J.6
Johansen, J.7
-
20
-
-
84874489560
-
Keap1-nrf2 signaling: A target for cancer prevention by sulforaphane
-
Kensler, T.W., Egner, P. A., Agyeman, A. S., Visvanathan, K., Groopman, J. D., Chen, J.-G., Chen, T.-Y., Fahey, J. W. and Talalay, P. (2013). Keap1-nrf2 signaling: a target for cancer prevention by sulforaphane. Top. Curr. Chem. 329, 163-177.
-
(2013)
Top. Curr. Chem.
, vol.329
, pp. 163-177
-
-
Kensler, T.W.1
Egner, P.A.2
Agyeman, A.S.3
Visvanathan, K.4
Groopman, J.D.5
Chen, J.-G.6
Chen, T.-Y.7
Fahey, J.W.8
Talalay, P.9
-
21
-
-
0030240429
-
A comparative analysis of juvenile hormone metabolyzing enzymes in two species of Drosophila during development
-
Khlebodarova, T. M., Gruntenko, N. E., Grenback, L. G., Sukhanova, M. Z., Mazurov, M. M., Rauschenbach, I. Y., Tomas, B. A. and Hammock, B. D. (1996). A comparative analysis of juvenile hormone metabolyzing enzymes in two species of Drosophila during development. Insect Biochem. Mol. Biol. 26, 829-835.
-
(1996)
Insect Biochem. Mol. Biol.
, vol.26
, pp. 829-835
-
-
Khlebodarova, T.M.1
Gruntenko, N.E.2
Grenback, L.G.3
Sukhanova, M.Z.4
Mazurov, M.M.5
Rauschenbach, I.Y.6
Tomas, B.A.7
Hammock, B.D.8
-
22
-
-
3543008924
-
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-basedE3ligase to regulate proteasomal degradation of Nrf2
-
Kobayashi, A., Kang, M.-I., Okawa, H., Ohtsuji, M., Zenke, Y., Chiba, T., Igarashi, K. and Yamamoto, M. (2004). Oxidative stress sensor Keap1 functions as an adaptor for Cul3-basedE3ligase to regulate proteasomal degradation of Nrf2. Mol. Cell. Biol. 24, 7130-7139.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7130-7139
-
-
Kobayashi, A.1
Kang, M.-I.2
Okawa, H.3
Ohtsuji, M.4
Zenke, Y.5
Chiba, T.6
Igarashi, K.7
Yamamoto, M.8
-
23
-
-
58249117780
-
The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds
-
Kobayashi, M., Li, L., Iwamoto, N., Nakajima-Takagi, Y., Kaneko, H., Nakayama, Y., Eguchi, M., Wada, Y., Kumagai, Y. and Yamamoto, M. (2009). The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. Mol. Cell. Biol. 29, 493-502.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 493-502
-
-
Kobayashi, M.1
Li, L.2
Iwamoto, N.3
Nakajima-Takagi, Y.4
Kaneko, H.5
Nakayama, Y.6
Eguchi, M.7
Wada, Y.8
Kumagai, Y.9
Yamamoto, M.10
-
24
-
-
0037424262
-
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival
-
Kwak, M.-K., Wakabayashi, N., Itoh, K., Motohashi, H., Yamamoto, M. and Kensler, T.W. (2003). Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival. J. Biol. Chem. 278, 8135-8145.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8135-8145
-
-
Kwak, M.-K.1
Wakabayashi, N.2
Itoh, K.3
Motohashi, H.4
Yamamoto, M.5
Kensler, T.W.6
-
25
-
-
0038146898
-
Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis
-
Lee, J.-M., Calkins, M. J., Chan, K., Kan, Y. W. and Johnson, J. A. (2003). Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis. J. Biol. Chem. 278, 12029-12038.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12029-12038
-
-
Lee, J.-M.1
Calkins, M.J.2
Chan, K.3
Kan, Y.W.4
Johnson, J.A.5
-
26
-
-
34047268764
-
The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice
-
Liby, K., Royce, D. B., Williams, C. R., Risingsong, R., Yore, M. M., Honda, T., Gribble, G. W., Dmitrovsky, E., Sporn, T. A. and Sporn, M. B. (2007). The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice. Cancer Res. 67, 2414-2419.
-
(2007)
Cancer Res.
, vol.67
, pp. 2414-2419
-
-
Liby, K.1
Royce, D.B.2
Williams, C.R.3
Risingsong, R.4
Yore, M.M.5
Honda, T.6
Gribble, G.W.7
Dmitrovsky, E.8
Sporn, T.A.9
Sporn, M.B.10
-
27
-
-
77957237159
-
Globalmapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis
-
Malhotra, D., Portales-Casamar, E., Singh, A., Srivastava, S., Arenillas, D., Happel, C., Shyr, C., Wakabayashi, N., Kensler, T. W., Wasserman, W. W. et al. (2010). Globalmapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis. Nucleic Acids Res. 38, 5718-5734.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 5718-5734
-
-
Malhotra, D.1
Portales-Casamar, E.2
Singh, A.3
Srivastava, S.4
Arenillas, D.5
Happel, C.6
Shyr, C.7
Wakabayashi, N.8
Kensler, T.W.9
Wasserman, W.W.10
-
28
-
-
0031646521
-
A cap 'n' collar protein isoform contains a selective Hox repressor function
-
McGinnis, N., Ragnhildstveit, E., Veraksa, A. and McGinnis, W. (1998). A cap 'n' collar protein isoform contains a selective Hox repressor function. Development 125, 4553-4564.
-
(1998)
Development
, vol.125
, pp. 4553-4564
-
-
McGinnis, N.1
Ragnhildstveit, E.2
Veraksa, A.3
McGinnis, W.4
-
29
-
-
0037821802
-
Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression
-
McMahon, M., Itoh, K., Yamamoto, M. and Hayes, J. D. (2003). Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression. J. Biol. Chem. 278, 21592-21600.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 21592-21600
-
-
McMahon, M.1
Itoh, K.2
Yamamoto, M.3
Hayes, J.D.4
-
30
-
-
33747728194
-
Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: A two-site interaction model for the Nrf2-Keap1 complex
-
McMahon, M., Thomas, N., Itoh, K., Yamamoto, M. and Hayes, J. D. (2006). Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex. J. Biol. Chem. 281, 24756-24768.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 24756-24768
-
-
McMahon, M.1
Thomas, N.2
Itoh, K.3
Yamamoto, M.4
Hayes, J.D.5
-
31
-
-
37349004797
-
Kruppel homolog 1 (Kr-h1) mediates juvenile hormone action during metamorphosis of Drosophila melanogaster
-
Minakuchi, C., Zhou, X. and Riddiford, L. M. (2008). Kruppel homolog 1 (Kr-h1) mediates juvenile hormone action during metamorphosis of Drosophila melanogaster. Mech. Dev. 125, 91-105.
-
(2008)
Mech. Dev.
, vol.125
, pp. 91-105
-
-
Minakuchi, C.1
Zhou, X.2
Riddiford, L.M.3
-
32
-
-
80052452088
-
Transcriptional regulation of xenobiotic detoxification in Drosophila
-
Misra, J. R., Horner, M. A., Lam, G. and Thummel, C. S. (2011). Transcriptional regulation of xenobiotic detoxification in Drosophila. Genes Dev. 25, 1796-1806.
-
(2011)
Genes Dev.
, vol.25
, pp. 1796-1806
-
-
Misra, J.R.1
Horner, M.A.2
Lam, G.3
Thummel, C.S.4
-
33
-
-
0028061444
-
Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region
-
Moi, P., Chan, K., Asunis, I., Cao, A. and Kan, Y. W. (1994). Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. Proc. Natl. Acad. Sci. USA 91, 9926-9930.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9926-9930
-
-
Moi, P.1
Chan, K.2
Asunis, I.3
Cao, A.4
Kan, Y.W.5
-
34
-
-
33750605111
-
Pharmacogenomics of phenolic antioxidant butylated hydroxyanisole (BHA) in the small intestine and liver of Nrf2 knockout and C57BL/6J mice
-
Nair, S., Xu, C., Shen, G., Hebbar, V., Gopalakrishnan, A., Hu, R., Jain, M. R., Lin, W., Keum, Y.-S., Liew, C. et al. (2006). Pharmacogenomics of phenolic antioxidant butylated hydroxyanisole (BHA) in the small intestine and liver of Nrf2 knockout and C57BL/6J mice. Pharm. Res. 23, 2621-2637.
-
(2006)
Pharm. Res.
, vol.23
, pp. 2621-2637
-
-
Nair, S.1
Xu, C.2
Shen, G.3
Hebbar, V.4
Gopalakrishnan, A.5
Hu, R.6
Jain, M.R.7
Lin, W.8
Keum, Y.-S.9
Liew, C.10
-
35
-
-
79953046943
-
A cis-regulatory map of the Drosophila genome
-
Nègre, N., Brown, C. D., Ma, L., Bristow, C. A., Miller, S. W., Wagner, U., Kheradpour, P., Eaton, M. L., Loriaux, P., Sealfon, R. et al. (2011). A cis-regulatory map of the Drosophila genome. Nature 471, 527-531.
-
(2011)
Nature
, vol.471
, pp. 527-531
-
-
Nègre, N.1
Brown, C.D.2
Ma, L.3
Bristow, C.A.4
Miller, S.W.5
Wagner, U.6
Kheradpour, P.7
Eaton, M.L.8
Loriaux, P.9
Sealfon, R.10
-
36
-
-
77649261371
-
Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains
-
Ogura, T., Tong, K. I., Mio, K., Maruyama, Y., Kurokawa, H., Sato, C. and Yamamoto, M. (2010). Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains. Proc. Natl. Acad. Sci. USA 107, 2842-2847.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 2842-2847
-
-
Ogura, T.1
Tong, K.I.2
Mio, K.3
Maruyama, Y.4
Kurokawa, H.5
Sato, C.6
Yamamoto, M.7
-
37
-
-
84861699772
-
Dimer formation via the homeodomain is required for function and specificity of Sex combs reduced in Drosophila
-
Papadopoulos, D. K., Skouloudaki, K., Adachi, Y., Samakovlis, C. and Gehring, W. J. (2012). Dimer formation via the homeodomain is required for function and specificity of Sex combs reduced in Drosophila. Dev. Biol. 367, 78-89.
-
(2012)
Dev. Biol.
, vol.367
, pp. 78-89
-
-
Papadopoulos, D.K.1
Skouloudaki, K.2
Adachi, Y.3
Samakovlis, C.4
Gehring, W.J.5
-
38
-
-
1342268248
-
Immunostaining of whole-mount imaginal discs
-
Phalle Bde, S. (2004). Immunostaining of whole-mount imaginal discs. Methods Mol. Biol. 247, 373-387.
-
(2004)
Methods Mol. Biol.
, vol.247
, pp. 373-387
-
-
de Phalle, B.S.1
-
39
-
-
77950553993
-
Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity
-
Pi, J., Leung, L., Xue, P., Wang, W., Hou, Y., Liu, D., Yehuda-Shnaidman, E., Lee, C., Lau, J., Kurtz, T. W. et al. (2010). Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity. J. Biol. Chem. 285, 9292-9300.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 9292-9300
-
-
Pi, J.1
Leung, L.2
Xue, P.3
Wang, W.4
Hou, Y.5
Liu, D.6
Yehuda-Shnaidman, E.7
Lee, C.8
Lau, J.9
Kurtz, T.W.10
-
40
-
-
51649088949
-
Cross-regulatory protein-protein interactions between Hox and Pax transcription factors
-
Plaza, S., Prince, F., Adachi, Y., Punzo, C., Cribbs, D. L. and Gehring, W. J. (2008). Cross-regulatory protein-protein interactions between Hox and Pax transcription factors. Proc. Natl. Acad. Sci. USA 105, 13439-13444.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 13439-13444
-
-
Plaza, S.1
Prince, F.2
Adachi, Y.3
Punzo, C.4
Cribbs, D.L.5
Gehring, W.J.6
-
41
-
-
84878664805
-
How does juvenile hormone control insect metamorphosis and reproduction?
-
Riddiford, L. M. (2012). How does juvenile hormone control insect metamorphosis and reproduction? Gen. Comp. Endocrinol. 179, 477-484.
-
(2012)
Gen. Comp. Endocrinol.
, vol.179
, pp. 477-484
-
-
Riddiford, L.M.1
-
42
-
-
77950482681
-
A role for juvenile hormone in the prepupal development of Drosophila melanogaster
-
Riddiford, L. M., Truman, J. W., Mirth, C. K. and Shen, Y.-C. (2010). A role for juvenile hormone in the prepupal development of Drosophila melanogaster. Development 137, 1117-1126.
-
(2010)
Development
, vol.137
, pp. 1117-1126
-
-
Riddiford, L.M.1
Truman, J.W.2
Mirth, C.K.3
Shen, Y.-C.4
-
43
-
-
77955219909
-
Characterization of juvenile hormone epoxide hydrolase and related genes in the larval development of the silkworm Bombyx mori
-
Seino, A., Ogura, T., Tsubota, T., Shimomura, M., Nakakura, T., Tan, A., Mita, K., Shinoda, T., Nakagawa, Y. and Shiotsuki, T. (2010). Characterization of juvenile hormone epoxide hydrolase and related genes in the larval development of the silkworm Bombyx mori. Biosci. Biotechnol. Biochem. 74, 1421-1429.
-
(2010)
Biosci. Biotechnol. Biochem.
, vol.74
, pp. 1421-1429
-
-
Seino, A.1
Ogura, T.2
Tsubota, T.3
Shimomura, M.4
Nakakura, T.5
Tan, A.6
Mita, K.7
Shinoda, T.8
Nakagawa, Y.9
Shiotsuki, T.10
-
44
-
-
79954424076
-
Nrf2: Control of sensitivity to carcinogens
-
Slocum, S. L. and Kensler, T.W. (2011). Nrf2: control of sensitivity to carcinogens. Arch. Toxicol. 85, 273-284.
-
(2011)
Arch. Toxicol.
, vol.85
, pp. 273-284
-
-
Slocum, S.L.1
Kensler, T.W.2
-
45
-
-
34548772935
-
Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2
-
Sun, Z., Zhang, S., Chan, J. Y. and Zhang, D. D. (2007). Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2. Mol. Cell. Biol. 27, 6334-6349.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 6334-6349
-
-
Sun, Z.1
Zhang, S.2
Chan, J.Y.3
Zhang, D.D.4
-
46
-
-
0037201949
-
Role of antioxidants in paraquat toxicity
-
Suntres, Z. E. (2002). Role of antioxidants in paraquat toxicity. Toxicology 180, 65-77.
-
(2002)
Toxicology
, vol.180
, pp. 65-77
-
-
Suntres, Z.E.1
-
47
-
-
37749024370
-
Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila
-
Sykiotis, G. P. and Bohmann, D. (2008). Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila. Dev. Cell 14, 76-85.
-
(2008)
Dev. Cell
, vol.14
, pp. 76-85
-
-
Sykiotis, G.P.1
Bohmann, D.2
-
48
-
-
78751703950
-
Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
-
Taguchi, K., Motohashi, H. and Yamamoto, M. (2011). Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution. Genes Cells 16, 123-140.
-
(2011)
Genes Cells
, vol.16
, pp. 123-140
-
-
Taguchi, K.1
Motohashi, H.2
Yamamoto, M.3
-
49
-
-
84864461148
-
Validation of the multiple sensor mechanism of the Keap1-Nrf2 system
-
Takaya, K., Suzuki, T., Motohashi, H., Onodera, K., Satomi, S., Kensler, T. W. and Yamamoto, M. (2012). Validation of the multiple sensor mechanism of the Keap1-Nrf2 system. Free Radic. Biol. Med. 53, 817-827.
-
(2012)
Free Radic. Biol. Med.
, vol.53
, pp. 817-827
-
-
Takaya, K.1
Suzuki, T.2
Motohashi, H.3
Onodera, K.4
Satomi, S.5
Kensler, T.W.6
Yamamoto, M.7
-
50
-
-
0037106099
-
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
-
Thimmulappa, R. K., Mai, K. H., Srisuma, S., Kensler, T. W., Yamamoto, M. and Biswal, S. (2002). Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res. 62, 5196-5203.
-
(2002)
Cancer Res.
, vol.62
, pp. 5196-5203
-
-
Thimmulappa, R.K.1
Mai, K.H.2
Srisuma, S.3
Kensler, T.W.4
Yamamoto, M.5
Biswal, S.6
-
51
-
-
33344463325
-
Keap1 recruits Neh2 through binding to ETGE and DLG motifs: Characterization of the two-site molecular recognition model
-
Tong, K. I., Katoh, Y., Kusunoki, H., Itoh, K., Tanaka, T. and Yamamoto, M. (2006). Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model. Mol. Cell. Biol. 26, 2887-2900.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 2887-2900
-
-
Tong, K.I.1
Katoh, Y.2
Kusunoki, H.3
Itoh, K.4
Tanaka, T.5
Yamamoto, M.6
-
52
-
-
0027304431
-
Juvenile hormone epoxide hydrolase. Photoaffinity labeling, purification, and characterization from tobacco hornworm eggs
-
Touhara, K. and Prestwich, G. D. (1993). Juvenile hormone epoxide hydrolase. Photoaffinity labeling, purification, and characterization from tobacco hornworm eggs. J. Biol. Chem. 268, 19604-19609.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 19604-19609
-
-
Touhara, K.1
Prestwich, G.D.2
-
53
-
-
84874655208
-
Nrf2 regulates haematopoietic stem cell function
-
Tsai, J. J., Dudakov, J. A., Takahashi, K., Shieh, J.-H., Velardi, E., Holland, A. M., Singer, N. V., West, M. L., Smith, O. M., Young, L. F. et al. (2013). Nrf2 regulates haematopoietic stem cell function. Nat. Cell Biol. 15, 309-316.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 309-316
-
-
Tsai, J.J.1
Dudakov, J.A.2
Takahashi, K.3
Shieh, J.-H.4
Velardi, E.5
Holland, A.M.6
Singer, N.V.7
West, M.L.8
Smith, O.M.9
Young, L.F.10
-
54
-
-
0029906134
-
Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:Quinone oxidoreductase1 gene
-
Venugopal, R. and Jaiswal, A. K. (1996). Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene. Proc. Natl. Acad. Sci. USA 93, 14960-14965.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14960-14965
-
-
Venugopal, R.1
Jaiswal, A.K.2
-
55
-
-
0033792944
-
Cap 'n' collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress deformed homeotic function in the Drosophila head
-
Veraksa, A., McGinnis, N., Li, X., Mohler, J. and McGinnis, W. (2000). Cap 'n' collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress deformed homeotic function in the Drosophila head. Development 127, 4023-4037.
-
(2000)
Development
, vol.127
, pp. 4023-4037
-
-
Veraksa, A.1
McGinnis, N.2
Li, X.3
Mohler, J.4
McGinnis, W.5
-
56
-
-
55949121452
-
Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences
-
Vincenz, C. and Kerppola, T. K. (2008). Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences. Proc. Natl. Acad. Sci. USA 105, 16572-16577.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 16572-16577
-
-
Vincenz, C.1
Kerppola, T.K.2
-
57
-
-
0029046128
-
The effects of phenobarbital pretreatment on the metabolism and toxicity of paraoxon in the mouse
-
Vitarius, J. A., O'Shaughnessy, J. A. and Sultatos, L. G. (1995). The effects of phenobarbital pretreatment on the metabolism and toxicity of paraoxon in the mouse. Pharmacol. Toxicol. 77, 16-22.
-
(1995)
Pharmacol. Toxicol.
, vol.77
, pp. 16-22
-
-
Vitarius, J.A.1
O'Shaughnessy, J.A.2
Sultatos, L.G.3
-
58
-
-
0242329881
-
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
-
Wakabayashi, N., Itoh, K., Wakabayashi, J., Motohashi, H., Noda, S., Takahashi, S., Imakado, S., Kotsuji, T., Otsuka, F., Roop, D. R. et al. (2003). Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation. Nat. Genet. 35, 238-245.
-
(2003)
Nat. Genet.
, vol.35
, pp. 238-245
-
-
Wakabayashi, N.1
Itoh, K.2
Wakabayashi, J.3
Motohashi, H.4
Noda, S.5
Takahashi, S.6
Imakado, S.7
Kotsuji, T.8
Otsuka, F.9
Roop, D.R.10
-
59
-
-
34848827480
-
Subcellular localization and cytoplasmic complex status of endogenous Keap1
-
Watai, Y., Kobayashi, A., Nagase, H., Mizukami, M., McEvoy, J., Singer, J. D., Itoh, K. and Yamamoto, M. (2007). Subcellular localization and cytoplasmic complex status of endogenous Keap1. Genes Cells 12, 1163-1178.
-
(2007)
Genes Cells
, vol.12
, pp. 1163-1178
-
-
Watai, Y.1
Kobayashi, A.2
Nagase, H.3
Mizukami, M.4
McEvoy, J.5
Singer, J.D.6
Itoh, K.7
Yamamoto, M.8
-
60
-
-
66749112860
-
Genetic versus chemoprotective activation of Nrf2 signaling: Overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoidtreated mice
-
Yates, M. S., Tran, Q. T., Dolan, P. M., Osburn, W. O., Shin, S., McCulloch, C. C., Silkworth, J. B., Taguchi, K., Yamamoto, M., Williams, C. R. et al. (2009). Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoidtreated mice. Carcinogenesis 30, 1024-1031.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1024-1031
-
-
Yates, M.S.1
Tran, Q.T.2
Dolan, P.M.3
Osburn, W.O.4
Shin, S.5
McCulloch, C.C.6
Silkworth, J.B.7
Taguchi, K.8
Yamamoto, M.9
Williams, C.R.10
|