The insect neuropeptide PTTH activates receptor tyrosine kinase torso to initiate metamorphosis

Science

Volumn 326, Issue 5958, 2009, Pages 1403-1405

  Rewitz, Kim F ^a   Yamanaka, Naoki ^a   Gilbert, Lawrence I ^b   O'Connor, Michael B ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSECT NEUROPEPTIDE; MITOGEN ACTIVATED PROTEIN KINASE; NEUROPEPTIDE; PROTEIN TYROSINE KINASE; PROTHORACICOTROPIC HORMONE; UNCLASSIFIED DRUG;

EMBRYO; ENZYME ACTIVITY; FLY; HORMONE; LARVA; MATURATION; METAMORPHOSIS;

ARTICLE; CONTROLLED STUDY; DROSOPHILA; EMBRYO; EMBRYO CELL; EMBRYO DEVELOPMENT; HORMONE RELEASE; INSECT GENOME; LARVA; METAMORPHOSIS; NONHUMAN; ORGAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; PROTHORACIC GLAND; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TORSO GENE;

AMINO ACID SEQUENCE; ANIMALS; BOMBYX; CELL LINE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INSECT HORMONES; LARVA; LIGANDS; METAMORPHOSIS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NEURONS; PHOSPHORYLATION; PUPA; RECEPTOR PROTEIN-TYROSINE KINASES; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

HEXAPODA;

EID: 71549168637     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1176450     Document Type: Article

References (21)

1. J. Colombani et al., Science 310, 667 (2005).
2. S. Layalle, N. Arquier, P. Leopold, Dev. Cell 15, 568 (2008).
3. Z. McBrayer et al., Dev. Cell 13, 857 (2007).
4. C. K. Mirth, L. M. Riddiford, Bioessays 29, 344 (2007).
5. S. M. Popa, D. K. Clifton, R. A. Steiner, Annu. Rev. Physiol. 70, 213 (2008).
6. A. Kawakami et al., Science 247, 1333 (1990).
7. R. Rybczynski, in Comprehensive Molecular Insect Science, L. I. Gilbert, K. Iatrou, S. Gill, Eds. (Elsevier, Oxford, 2005), vol.3, pp. 61-123.
8. L. I. Gilbert, R. Rybczynski, J. T. Warren, Annu. Rev. Entomol. 47, 883 (2002).
9. T. Noguti et al., FEBS Lett. 376, 251 (1995).
10. J. L. Lin, S. H. Gu, J. Insect Physiol. 53, 622 (2007).
11. K. F. Rewitz et al., Insect Biochem. Mol. Biol. 39, 475 (2009).
12. R. Rybczynski, S. C. Bell, L. I. Gilbert, Mol. Cell. Endocrinol. 184, 1 (2001).
13. R. Rybczynski, L. I. Gilbert, Mol. Cell. Endocrinol. 205, 159 (2003).
14. J. Casanova, G. Struhl, Genes Dev. 3, 2025 (1989).
15. W. X. Li, Dev. Dyn. 232, 656 (2005).
16. F. Sprenger, L. M. Stevens, C. Nusslein-Volhard, Nature 338, 478 (1989).
17. A. Casali, J. Casanova, Development 128, 1709 (2001).
18. P. E. Caldwell, M. Walkiewicz, M. Stern, Curr. Biol. 15, 1785 (2005).
19. S. Mishra, S. M. Smolik, M. A. Forte, P. J. Stork, Curr. Biol. 15, 366 (2005).
20. H. Ono et al., Dev. Biol. 298, 555 (2006).
21. K.F.R. was supported by a postdoctoral fellowship from the Danish Natural Science Research Council (grant no. 272-07-0340). M.B.O. is an investigator with the Howard Hughes Medical Institute. We are grateful to our collaborators J. T. Warren and R. Rybczynski and to reviewers for helpful comments. We also thank H. Kataoka for Bombyx PTTH. The GenBank accession number for Bombyx Torso is GQ477743.