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Volumn 97, Issue 4, 2016, Pages 825-838

Beyond the inflammasome: Regulatory nod-like receptor modulation of the host immune response following virus exposure

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERFERON; INTERLEUKIN 18; INTERLEUKIN 1BETA; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; RETINOIC ACID INDUCIBLE PROTEIN I; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; ISOPROTEIN; MITOCHONDRIAL PROTEIN; NLRX1 PROTEIN, HUMAN; NOD1 PROTEIN, HUMAN; NOD2 PROTEIN, HUMAN; TOLL LIKE RECEPTOR;

EID: 84963764576     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/jgv.0.000401     Document Type: Review
Times cited : (99)

References (110)
  • 1
    • 11144289688 scopus 로고    scopus 로고
    • The Crohn’s disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
    • Abbott, D. W., Wilkins, A., Asara, J. M. & Cantley, L. C. (2004). The Crohn’s disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO. Curr Biol 14, 2217–2227.
    • (2004) Curr Biol , vol.14 , pp. 2217-2227
    • Abbott, D.W.1    Wilkins, A.2    Asara, J.M.3    Cantley, L.C.4
  • 2
    • 78650630756 scopus 로고    scopus 로고
    • Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1
    • Abdul-Sater, A. A., Saïd-Sadier, N., Lam, V. M., Singh, B., Pettengill, M. A., Soares, F., Tattoli, I., Lipinski, S., Girardin, S. E. & other authors (2010). Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1. J Biol Chem 285, 41637–41645.
    • (2010) J Biol Chem , vol.285 , pp. 41637-41645
    • Abdul-Sater, A.A.1    Saïd-Sadier, N.2    Lam, V.M.3    Singh, B.4    Pettengill, M.A.5    Soares, F.6    Tattoli, I.7    Lipinski, S.8    Girardin, S.E.9
  • 3
    • 1642285783 scopus 로고    scopus 로고
    • NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
    • Agostini, L., Martinon, F., Burns, K., McDermott, M. F., Hawkins, P. N. & Tschopp, J. (2004). NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20, 319–325.
    • (2004) Immunity , vol.20 , pp. 319-325
    • Agostini, L.1    Martinon, F.2    Burns, K.3    McDermott, M.F.4    Hawkins, P.N.5    Tschopp, J.6
  • 4
    • 79959350721 scopus 로고    scopus 로고
    • NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NFkB signaling pathways
    • Allen, I. C., Moore, C. B., Schneider, M., Lei, Y., Davis, B. K., Scull, M. A., Gris, D., Roney, K. E., Zimmermann, A. G. & other authors (2011). NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NFkB signaling pathways. Immunity 34, 854–865.
    • (2011) Immunity , vol.34 , pp. 854-865
    • Allen, I.C.1    Moore, C.B.2    Schneider, M.3    Lei, Y.4    Davis, B.K.5    Scull, M.A.6    Gris, D.7    Roney, K.E.8    Zimmermann, A.G.9
  • 6
    • 84861460062 scopus 로고    scopus 로고
    • NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-kB signaling
    • Allen, I. C., Wilson, J. E., Schneider, M., Lich, J. D., Roberts, R. A., Arthur, J. C., Woodford, R. M., Davis, B. K., Uronis, J. M. & other authors (2012b). NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-kB signaling. Immunity 36, 742–754.
    • (2012) Immunity , vol.36 , pp. 742-754
    • Allen, I.C.1    Wilson, J.E.2    Schneider, M.3    Lich, J.D.4    Roberts, R.A.5    Arthur, J.C.6    Woodford, R.M.7    Davis, B.K.8    Uronis, J.M.9
  • 7
    • 0038066634 scopus 로고    scopus 로고
    • Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells
    • Anders, M., Christian, C., McMahon, M., McCormick, F. & Korn, W. M. (2003). Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells. Cancer Res 63, 2088–2095.
    • (2003) Cancer Res , vol.63 , pp. 2088-2095
    • Anders, M.1    Christian, C.2    McMahon, M.3    McCormick, F.4    Korn, W.M.5
  • 9
    • 38449087767 scopus 로고    scopus 로고
    • Heat shock protein 90 associateswithMonarch-1 and regulates its ability to promote degradation of NF-kB-inducing kinase
    • Arthur, J.C., Lich, J.D., Aziz, R.K., Kotb, M. & Ting, J.P. (2007).Heat shock protein 90 associateswithMonarch-1 and regulates its ability to promote degradation of NF-kB-inducing kinase. J Immunol 179, 6291–6296.
    • (2007) J Immunol , vol.179 , pp. 6291-6296
    • Arthur, J.C.1    Lich, J.D.2    Aziz, R.K.3    Kotb, M.4    Ting, J.P.5
  • 10
    • 76249085207 scopus 로고    scopus 로고
    • Nucleotide oligomerization binding domain-like receptor signaling enhances dendritic cellmediated cross-priming in vivo
    • Asano, J., Tada, H., Onai, N., Sato, T., Horie, Y., Fujimoto, Y., Fukase, K., Suzuki, A., Mak, T. W. & Ohteki, T. (2010). Nucleotide oligomerization binding domain-like receptor signaling enhances dendritic cellmediated cross-priming in vivo. J Immunol 184, 736–745.
    • (2010) J Immunol , vol.184 , pp. 736-745
    • Asano, J.1    Tada, H.2    Onai, N.3    Sato, T.4    Horie, Y.5    Fujimoto, Y.6    Fukase, K.7    Suzuki, A.8    Mak, T.W.9    Ohteki, T.10
  • 11
    • 84855253242 scopus 로고    scopus 로고
    • Expression, purification, and characterization of recombinant NOD1 (NLRC1): A NLR family member
    • Askari, N., Correa, R. G., Zhai, D. & Reed, J. C. (2012). Expression, purification, and characterization of recombinant NOD1 (NLRC1): a NLR family member. J Biotechnol 157, 75–81.
    • (2012) J Biotechnol , vol.157 , pp. 75-81
    • Askari, N.1    Correa, R.G.2    Zhai, D.3    Reed, J.C.4
  • 12
    • 77956409550 scopus 로고    scopus 로고
    • NLRC5 limits the activation of inflammatory pathways
    • Benko, S., Magalhaes, J. G., Philpott, D. J. & Girardin, S. E. (2010). NLRC5 limits the activation of inflammatory pathways. J Immunol 185, 1681–1691.
    • (2010) J Immunol , vol.185 , pp. 1681-1691
    • Benko, S.1    Magalhaes, J.G.2    Philpott, D.J.3    Girardin, S.E.4
  • 13
    • 77951911814 scopus 로고    scopus 로고
    • Control of infection by pyroptosis and autophagy: Role of TLR and NLR
    • Bortoluci, K. R. & Medzhitov, R. (2010). Control of infection by pyroptosis and autophagy: role of TLR and NLR. Cell Mol Life Sci 67, 1643–1651.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 1643-1651
    • Bortoluci, K.R.1    Medzhitov, R.2
  • 14
    • 84880923978 scopus 로고    scopus 로고
    • Newly described pattern recognition receptors team up against intracellular pathogens
    • Broz, P. & Monack, D. M. (2013). Newly described pattern recognition receptors team up against intracellular pathogens. Nat Rev Immunol 13, 551–565.
    • (2013) Nat Rev Immunol , vol.13 , pp. 551-565
    • Broz, P.1    Monack, D.M.2
  • 16
  • 17
    • 0025271098 scopus 로고
    • Retinoic acidinduced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-a)
    • Collins, S. J., Robertson, K. A. & Mueller, L. (1990). Retinoic acidinduced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-a). Mol Cell Biol 10, 2154–2163.
    • (1990) Mol Cell Biol , vol.10 , pp. 2154-2163
    • Collins, S.J.1    Robertson, K.A.2    Mueller, L.3
  • 18
    • 24044515544 scopus 로고    scopus 로고
    • CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function
    • Conti, B. J., Davis, B. K., Zhang, J., O’connor, W., Jr, Williams, K. L. & Ting, J. P. (2005). CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function. J Biol Chem 280, 18375–18385.
    • (2005) J Biol Chem , vol.280 , pp. 18375-18385
    • Conti, B.J.1    Davis, B.K.2    Zhang, J.3    O’Connor, W.4    Williams, K.L.5    Ting, J.P.6
  • 21
    • 63649145255 scopus 로고    scopus 로고
    • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
    • Fernandes-Alnemri, T., Yu, J. W., Datta, P., Wu, J. & Alnemri, E. S. (2009). AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458, 509–513.
    • (2009) Nature , vol.458 , pp. 509-513
    • Fernandes-Alnemri, T.1    Yu, J.W.2    Datta, P.3    Wu, J.4    Alnemri, E.S.5
  • 24
    • 38549084725 scopus 로고    scopus 로고
    • A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kB activation
    • Hasegawa, M., Fujimoto, Y., Lucas, P. C., Nakano, H., Fukase, K., Núñez, G. & Inohara, N. (2008). A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kB activation. EMBO J 27, 373–383.
    • (2008) EMBO J , vol.27 , pp. 373-383
    • Hasegawa, M.1    Fujimoto, Y.2    Lucas, P.C.3    Nakano, H.4    Fukase, K.5    Núñez, G.6    Inohara, N.7
  • 26
    • 84858762861 scopus 로고    scopus 로고
    • Structure and functional characterization of the RNA-binding element of the NLRX1 innate immune modulator
    • Hong, M., Yoon, S. I. & Wilson, I. A. (2012). Structure and functional characterization of the RNA-binding element of the NLRX1 innate immune modulator. Immunity 36, 337–347.
    • (2012) Immunity , vol.36 , pp. 337-347
    • Hong, M.1    Yoon, S.I.2    Wilson, I.A.3
  • 28
    • 79957466994 scopus 로고    scopus 로고
    • Innate immune defence: NOD2 and autophagy in the pathogenesis of Crohn’s disease
    • Hruz, P. & Eckmann, L. (2011). Innate immune defence: NOD2 and autophagy in the pathogenesis of Crohn’s disease. Swiss Med Wkly 140, w13135.
    • (2011) Swiss Med Wkly , vol.140
    • Hruz, P.1    Eckmann, L.2
  • 30
    • 0037458665 scopus 로고    scopus 로고
    • Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn’s disease
    • Inohara, N., Ogura, Y., Fontalba, A., Gutierrez, O., Pons, F., Crespo, J., Fukase, K., Inamura, S., Kusumoto, S. & other authors (2003). Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn’s disease. J Biol Chem 278, 5509–5512.
    • (2003) J Biol Chem , vol.278 , pp. 5509-5512
    • Inohara, N.1    Ogura, Y.2    Fontalba, A.3    Gutierrez, O.4    Pons, F.5    Crespo, J.6    Fukase, K.7    Inamura, S.8    Kusumoto, S.9
  • 31
    • 53349178089 scopus 로고    scopus 로고
    • STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
    • Ishikawa, H. & Barber, G. N. (2008). STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 455, 674–678.
    • (2008) Nature , vol.455 , pp. 674-678
    • Ishikawa, H.1    Barber, G.N.2
  • 32
    • 70349943834 scopus 로고    scopus 로고
    • STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
    • Ishikawa, H., Ma, Z. & Barber, G. N. (2009). STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature 461, 788–792.
    • (2009) Nature , vol.461 , pp. 788-792
    • Ishikawa, H.1    Ma, Z.2    Barber, G.N.3
  • 33
    • 84901002026 scopus 로고    scopus 로고
    • NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein
    • Jaworska, J., Coulombe, F., Downey, J., Tzelepis, F., Shalaby, K., Tattoli, I., Berube, J., Rousseau, S., Martin, J. G. & other authors (2014). NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein. Proc Natl Acad Sci USA 111, E2110–E2119.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. E2110-E2119
    • Jaworska, J.1    Coulombe, F.2    Downey, J.3    Tzelepis, F.4    Shalaby, K.5    Tattoli, I.6    Berube, J.7    Rousseau, S.8    Martin, J.G.9
  • 34
    • 84896346304 scopus 로고    scopus 로고
    • Noncanonical NF-kB pathway controls the production of type I interferons in antiviral innate immunity
    • Jin, J., Hu, H., Li, H. S., Yu, J., Xiao, Y., Brittain, G. C., Zou, Q., Cheng, X., Mallette, F. A. & other authors (2014). Noncanonical NF-kB pathway controls the production of type I interferons in antiviral innate immunity. Immunity 40, 342–354.
    • (2014) Immunity , vol.40 , pp. 342-354
    • Jin, J.1    Hu, H.2    Li, H.S.3    Yu, J.4    Xiao, Y.5    Brittain, G.C.6    Zou, Q.7    Cheng, X.8    Mallette, F.A.9
  • 35
    • 84900035120 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus infection activates NOD2-RIP2 signal pathway in MARC-145 cells
    • Jing, H., Fang, L., Wang, D., Ding, Z., Luo, R., Chen, H. & Xiao, S. (2014). Porcine reproductive and respiratory syndrome virus infection activates NOD2-RIP2 signal pathway in MARC-145 cells. Virology 458-459, 162–171.
    • (2014) Virology , vol.458-459 , pp. 162-171
    • Jing, H.1    Fang, L.2    Wang, D.3    Ding, Z.4    Luo, R.5    Chen, H.6    Xiao, S.7
  • 37
    • 84899922475 scopus 로고    scopus 로고
    • Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replication
    • Kapoor, A., Forman, M. & Arav-Boger, R. (2014). Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replication. PLoS One 9, e92704.
    • (2014) Plos One , vol.9
    • Kapoor, A.1    Forman, M.2    Arav-Boger, R.3
  • 38
    • 84894412231 scopus 로고    scopus 로고
    • Detection of enteric pathogens by the nodosome
    • Keestra, A. M. & Bäumler, A. J. (2014). Detection of enteric pathogens by the nodosome. Trends Immunol 35, 123–130.
    • (2014) Trends Immunol , vol.35 , pp. 123-130
    • Keestra, A.M.1    Bäumler, A.J.2
  • 39
    • 1342344961 scopus 로고    scopus 로고
    • Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors
    • Kim, J. G., Lee, S. J. & Kagnoff, M. F. (2004). Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors. Infect Immun 72, 1487–1495.
    • (2004) Infect Immun , vol.72 , pp. 1487-1495
    • Kim, J.G.1    Lee, S.J.2    Kagnoff, M.F.3
  • 40
    • 77950361417 scopus 로고    scopus 로고
    • Cytomegalovirus infection in patients with active inflammatory bowel disease
    • Kim, J. J., Simpson, N., Klipfel, N., Debose, R., Barr, N. & Laine, L. (2010). Cytomegalovirus infection in patients with active inflammatory bowel disease. Dig Dis Sci 55, 1059–1065.
    • (2010) Dig Dis Sci , vol.55 , pp. 1059-1065
    • Kim, J.J.1    Simpson, N.2    Klipfel, N.3    Debose, R.4    Barr, N.5    Laine, L.6
  • 41
    • 79958746242 scopus 로고    scopus 로고
    • Viral infection augments Nod1/2 signaling to potentiate lethality associated with secondary bacterial infections
    • Kim, Y. G., Park, J. H., Reimer, T., Baker, D. P., Kawai, T., Kumar, H., Akira, S., Wobus, C. & Núñez, G. (2011). Viral infection augments Nod1/2 signaling to potentiate lethality associated with secondary bacterial infections. Cell Host Microbe 9, 496–507.
    • (2011) Cell Host Microbe , vol.9 , pp. 496-507
    • Kim, Y.G.1    Park, J.H.2    Reimer, T.3    Baker, D.P.4    Kawai, T.5    Kumar, H.6    Akira, S.7    Wobus, C.8    Núñez, G.9
  • 44
    • 38049177193 scopus 로고    scopus 로고
    • The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction
    • Kufer, T. A., Kremmer, E., Adam, A. C., Philpott, D. J. & Sansonetti, P. J. (2008). The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction. Cell Microbiol 10, 477–486.
    • (2008) Cell Microbiol , vol.10 , pp. 477-486
    • Kufer, T.A.1    Kremmer, E.2    Adam, A.C.3    Philpott, D.J.4    Sansonetti, P.J.5
  • 45
    • 54449087343 scopus 로고    scopus 로고
    • Activation of the ERK signal transduction pathway by Epstein-Barr virus immediate-early protein Rta
    • Lee, Y. H., Chiu, Y. F., Wang, W. H., Chang, L. K. & Liu, S. T. (2008). Activation of the ERK signal transduction pathway by Epstein-Barr virus immediate-early protein Rta. J Gen Virol 89, 2437–2446.
    • (2008) J Gen Virol , vol.89 , pp. 2437-2446
    • Lee, Y.H.1    Chiu, Y.F.2    Wang, W.H.3    Chang, L.K.4    Liu, S.T.5
  • 46
    • 84863005844 scopus 로고    scopus 로고
    • The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy
    • Lei, Y., Wen, H., Yu, Y., Taxman, D. J., Zhang, L., Widman, D. G., Swanson, K. V., Wen, K. W., Damania, B. & other authors (2012). The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity 36, 933–946.
    • (2012) Immunity , vol.36 , pp. 933-946
    • Lei, Y.1    Wen, H.2    Yu, Y.3    Taxman, D.J.4    Zhang, L.5    Widman, D.G.6    Swanson, K.V.7    Wen, K.W.8    Damania, B.9
  • 47
    • 84877344662 scopus 로고    scopus 로고
    • The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy
    • Lei, Y., Wen, H. & Ting, J. P. (2013). The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy. Autophagy 9, 432–433.
    • (2013) Autophagy , vol.9 , pp. 432-433
    • Lei, Y.1    Wen, H.2    Ting, J.P.3
  • 48
    • 33846473862 scopus 로고    scopus 로고
    • Monarch-1 suppresses noncanonical NF-kB activation and p52-dependent chemokine expression in monocytes
    • Lich, J. D., Williams, K. L., Moore, C. B., Arthur, J. C., Davis, B. K., Taxman, D. J. & Ting, J. P. (2007). Monarch-1 suppresses noncanonical NF-kB activation and p52-dependent chemokine expression in monocytes. J Immunol 178, 1256–1260.
    • (2007) J Immunol , vol.178 , pp. 1256-1260
    • Lich, J.D.1    Williams, K.L.2    Moore, C.B.3    Arthur, J.C.4    Davis, B.K.5    Taxman, D.J.6    Ting, J.P.7
  • 49
    • 53149137461 scopus 로고    scopus 로고
    • Respiratory syncytial virus induces RelA release from cytoplasmic 100-kDa NF-kB2 complexes via a novel retinoic acid-inducible gene-I?NFkB- inducing kinase signaling pathway
    • Liu, P., Li, K., Garofalo, R. P. & Brasier, A. R. (2008). Respiratory syncytial virus induces RelA release from cytoplasmic 100-kDa NF-kB2 complexes via a novel retinoic acid-inducible gene-I?NFkB- inducing kinase signaling pathway. J Biol Chem 283, 23169–23178.
    • (2008) J Biol Chem , vol.283 , pp. 23169-23178
    • Liu, P.1    Li, K.2    Garofalo, R.P.3    Brasier, A.R.4
  • 50
    • 84885972767 scopus 로고    scopus 로고
    • Unsolved mysteries in NLR biology
    • Lupfer, C. & Kanneganti, T. D. (2013). Unsolved mysteries in NLR biology. Front Immunol 4, 285.
    • (2013) Front Immunol , vol.4 , pp. 285
    • Lupfer, C.1    Kanneganti, T.D.2
  • 53
    • 84896331177 scopus 로고    scopus 로고
    • NLRC3 puts the brakes on STING
    • Mangan, M. S. & Latz, E. (2014). NLRC3 puts the brakes on STING. Immunity 40, 305–306.
    • (2014) Immunity , vol.40 , pp. 305-306
    • Mangan, M.S.1    Latz, E.2
  • 55
    • 22444433175 scopus 로고    scopus 로고
    • NLRs join TLRs as innate sensors of pathogens
    • Martinon, F. & Tschopp, J. (2005). NLRs join TLRs as innate sensors of pathogens. Trends Immunol 26, 447–454.
    • (2005) Trends Immunol , vol.26 , pp. 447-454
    • Martinon, F.1    Tschopp, J.2
  • 56
    • 0036671894 scopus 로고    scopus 로고
    • The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
    • Martinon, F., Burns, K. & Tschopp, J. (2002). The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-β. Mol Cell 10, 417–426.
    • (2002) Mol Cell , vol.10 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 57
    • 83555176154 scopus 로고    scopus 로고
    • Nucleotide-binding oligomerization domain-like receptors and inflammasomes in the pathogenesis of non-microbial inflammation and diseases
    • Mason, D. R., Beck, P. L. & Muruve, D. A. (2012). Nucleotide-binding oligomerization domain-like receptors and inflammasomes in the pathogenesis of non-microbial inflammation and diseases. J Innate Immun 4, 16–30.
    • (2012) J Innate Immun , vol.4 , pp. 16-30
    • Mason, D.R.1    Beck, P.L.2    Muruve, D.A.3
  • 61
    • 84863336565 scopus 로고    scopus 로고
    • Pathogen sensing by nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP
    • Mo, J., Boyle, J. P., Howard, C. B., Monie, T. P., Davis, B. K. & Duncan, J. A. (2012). Pathogen sensing by nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP. J Biol Chem 287, 23057–23067.
    • (2012) J Biol Chem , vol.287 , pp. 23057-23067
    • Mo, J.1    Boyle, J.P.2    Howard, C.B.3    Monie, T.P.4    Davis, B.K.5    Duncan, J.A.6
  • 63
    • 53449085985 scopus 로고    scopus 로고
    • Modulation of adaptive immunity by different adjuvant-antigen combinations in mice lacking Nod2
    • Moreira, L. O., Smith, A. M., DeFreitas, A. A., Qualls, J. E., El Kasmi, K. C. & Murray, P. J. (2008). Modulation of adaptive immunity by different adjuvant-antigen combinations in mice lacking Nod2. Vaccine 26, 5808–5813.
    • (2008) Vaccine , vol.26 , pp. 5808-5813
    • Moreira, L.O.1    Smith, A.M.2    Defreitas, A.A.3    Qualls, J.E.4    El Kasmi, K.C.5    Murray, P.J.6
  • 67
    • 79960644913 scopus 로고    scopus 로고
    • Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication
    • Orlandi, C., Forlani, G., Tosi, G. & Accolla, R. S. (2011). Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication. J Transl Med 9, 106.
    • (2011) J Transl Med , vol.9 , pp. 106
    • Orlandi, C.1    Forlani, G.2    Tosi, G.3    Accolla, R.S.4
  • 68
    • 0035090589 scopus 로고    scopus 로고
    • Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade
    • Pleschka, S., Wolff, T., Ehrhardt, C., Hobom, G., Planz, O., Rapp, U. R. & Ludwig, S. (2001). Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade. Nat Cell Biol 3, 301–305.
    • (2001) Nat Cell Biol , vol.3 , pp. 301-305
    • Pleschka, S.1    Wolff, T.2    Ehrhardt, C.3    Hobom, G.4    Planz, O.5    Rapp, U.R.6    Ludwig, S.7
  • 69
    • 0031927822 scopus 로고    scopus 로고
    • Binding of human immunodeficiency virus type 1 to CD4 and CXCR4 receptors differentially regulates expression of inflammatory genes and activates the MEK/ERK signaling pathway
    • Popik, W., Hesselgesser, J. E. & Pitha, P. M. (1998). Binding of human immunodeficiency virus type 1 to CD4 and CXCR4 receptors differentially regulates expression of inflammatory genes and activates the MEK/ERK signaling pathway. J Virol 72, 6406–6413.
    • (1998) J Virol , vol.72 , pp. 6406-6413
    • Popik, W.1    Hesselgesser, J.E.2    Pitha, P.M.3
  • 72
    • 51849157938 scopus 로고    scopus 로고
    • Toll-like receptor 3 activation decreases porcine arterivirus infection
    • Sang, Y., Ross, C. R., Rowland, R. R. & Blecha, F. (2008). Toll-like receptor 3 activation decreases porcine arterivirus infection. Viral Immunol 21, 303–314.
    • (2008) Viral Immunol , vol.21 , pp. 303-314
    • Sang, Y.1    Ross, C.R.2    Rowland, R.R.3    Blecha, F.4
  • 73
    • 84865404917 scopus 로고    scopus 로고
    • The innate immune sensor NLRC3 attenuates Tolllike receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-kB
    • Schneider, M., Zimmermann, A. G., Roberts, R. A., Zhang, L., Swanson, K. V., Wen, H., Davis, B. K., Allen, I. C., Holl, E. K. & other authors (2012). The innate immune sensor NLRC3 attenuates Tolllike receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-kB. Nat Immunol 13, 823–831.
    • (2012) Nat Immunol , vol.13 , pp. 823-831
    • Schneider, M.1    Zimmermann, A.G.2    Roberts, R.A.3    Zhang, L.4    Swanson, K.V.5    Wen, H.6    Davis, B.K.7    Allen, I.C.8    Holl, E.K.9
  • 74
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder, K. & Tschopp, J. (2010). The inflammasomes. Cell 140, 821–832.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 75
    • 0029782304 scopus 로고    scopus 로고
    • Oxidative stress during viral infection: A review
    • Schwarz, K. B. (1996). Oxidative stress during viral infection: a review. Free Radic Biol Med 21, 641–649.
    • (1996) Free Radic Biol Med , vol.21 , pp. 641-649
    • Schwarz, K.B.1
  • 77
    • 69349084842 scopus 로고
    • (2009). Autophagy, antiviral immunity, and viral countermeasures
    • Shoji-Kawata, S. & Levine, B. (2009). Autophagy, antiviral immunity, and viral countermeasures. Biochim Biophys Acta 1793, 1478–1484.
    • (1793) Biochim Biophys Acta , pp. 1478-1484
    • Shoji-Kawata, S.1    Levine, B.2
  • 78
    • 77349118460 scopus 로고    scopus 로고
    • Pore formation triggered by Legionella spp. Is an Nlrc4 inflammasome-dependent host cell response that precedes pyroptosis
    • Silveira, T. N. & Zamboni, D. S. (2010). Pore formation triggered by Legionella spp. is an Nlrc4 inflammasome-dependent host cell response that precedes pyroptosis. Infect Immun 78, 1403–1413.
    • (2010) Infect Immun , vol.78 , pp. 1403-1413
    • Silveira, T.N.1    Zamboni, D.S.2
  • 83
    • 33244472793 scopus 로고    scopus 로고
    • Signalling pathways and molecular interactions of NOD1 and NOD2
    • Strober, W., Murray, P. J., Kitani, A. & Watanabe, T. (2006). Signalling pathways and molecular interactions of NOD1 and NOD2. Nat Rev Immunol 6, 9–20.
    • (2006) Nat Rev Immunol , vol.6 , pp. 9-20
    • Strober, W.1    Murray, P.J.2    Kitani, A.3    Watanabe, T.4
  • 84
    • 28444471235 scopus 로고    scopus 로고
    • Synergistic effect of Nod1 and Nod2 agonists with Toll-like receptor agonists on human dendritic cells to generate interleukin- 12 and T helper type 1 cells
    • Tada, H., Aiba, S., Shibata, K., Ohteki, T. & Takada, H. (2005). Synergistic effect of Nod1 and Nod2 agonists with Toll-like receptor agonists on human dendritic cells to generate interleukin- 12 and T helper type 1 cells. Infect Immun 73, 7967–7976.
    • (2005) Infect Immun , vol.73 , pp. 7967-7976
    • Tada, H.1    Aiba, S.2    Shibata, K.3    Ohteki, T.4    Takada, H.5
  • 86
    • 40249111682 scopus 로고    scopus 로고
    • NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kB and JNK pathways by inducing reactive oxygen species production
    • Tattoli, I., Carneiro, L. A., Jéhanno, M., Magalhaes, J. G., Shu, Y., Philpott, D. J., Arnoult, D. & Girardin, S. E. (2008). NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kB and JNK pathways by inducing reactive oxygen species production. EMBO Rep 9, 293–300.
    • (2008) EMBO Rep , vol.9 , pp. 293-300
    • Tattoli, I.1    Carneiro, L.A.2    Jéhanno, M.3    Magalhaes, J.G.4    Shu, Y.5    Philpott, D.J.6    Arnoult, D.7    Girardin, S.E.8
  • 87
    • 80054996890 scopus 로고    scopus 로고
    • Major histocompatibility complex class II transactivator CIITA is a viral restriction factor that targets human T-cell lymphotropic virus type 1 Tax-1 function and inhibits viral replication
    • Tosi, G., Forlani, G., Andresen, V., Turci, M., Bertazzoni, U., Franchini, G., Poli, G. & Accolla, R. S. (2011). Major histocompatibility complex class II transactivator CIITA is a viral restriction factor that targets human T-cell lymphotropic virus type 1 Tax-1 function and inhibits viral replication. J Virol 85, 10719–10729.
    • (2011) J Virol , vol.85 , pp. 10719-10729
    • Tosi, G.1    Forlani, G.2    Resen, V.3    Turci, M.4    Bertazzoni, U.5    Franchini, G.6    Poli, G.7    Accolla, R.S.8
  • 93
    • 84895498988 scopus 로고    scopus 로고
    • Nod-like receptor X-1 is required for rhinovirus-induced barrier dysfunction in airway epithelial cells
    • Unger, B. L., Ganesan, S., Comstock, A. T., Faris, A. N., Hershenson, M. B. & Sajjan, U. S. (2014). Nod-like receptor X-1 is required for rhinovirus-induced barrier dysfunction in airway epithelial cells. J Virol 88, 3705–3718.
    • (2014) J Virol , vol.88 , pp. 3705-3718
    • Unger, B.L.1    Ganesan, S.2    Comstock, A.T.3    Faris, A.N.4    Hershenson, M.B.5    Sajjan, U.S.6
  • 94
    • 84915815218 scopus 로고    scopus 로고
    • NOD-like receptors interfacing the immune and reproductive systems
    • Van Gorp, H., Kuchmiy, A., Van Hauwermeiren, F. & Lamkanfi, M. (2014). NOD-like receptors interfacing the immune and reproductive systems. FEBS J 281, 4568–4582.
    • (2014) FEBS J , vol.281 , pp. 4568-4582
    • Van Gorp, H.1    Kuchmiy, A.2    Van Hauwermeiren, F.3    Lamkanfi, M.4
  • 95
    • 84867222865 scopus 로고    scopus 로고
    • Respiratory syncytial virus infection augments NOD2 signaling in an IFN-β-dependent manner in human primary cells
    • Vissers, M., Remijn, T., Oosting, M., de Jong, D. J., Diavatopoulos, D. A., Hermans, P. W. & Ferwerda, G. (2012). Respiratory syncytial virus infection augments NOD2 signaling in an IFN-β-dependent manner in human primary cells. Eur J Immunol 42, 2727–2735.
    • (2012) Eur J Immunol , vol.42 , pp. 2727-2735
    • Vissers, M.1    Remijn, T.2    Oosting, M.3    De Jong, D.J.4    Diavatopoulos, D.A.5    Hermans, P.W.6    Ferwerda, G.7
  • 96
    • 64249098607 scopus 로고    scopus 로고
    • Evaluation of Nod-like receptor (NLR) effector domain interactions
    • Wagner, R. N., Proell, M., Kufer, T. A. & Schwarzenbacher, R. (2009). Evaluation of Nod-like receptor (NLR) effector domain interactions. PLoS One 4, e4931.
    • (2009) Plos One , vol.4
    • Wagner, R.N.1    Proell, M.2    Kufer, T.A.3    Schwarzenbacher, R.4
  • 97
    • 4444253690 scopus 로고    scopus 로고
    • NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
    • Watanabe, T., Kitani, A., Murray, P. J. & Strober, W. (2004). NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol 5, 800–808.
    • (2004) Nat Immunol , vol.5 , pp. 800-808
    • Watanabe, T.1    Kitani, A.2    Murray, P.J.3    Strober, W.4
  • 98
    • 77951784552 scopus 로고    scopus 로고
    • NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway
    • Watanabe, T., Asano, N., Fichtner-Feigl, S., Gorelick, P. L., Tsuji, Y., Matsumoto, Y., Chiba, T., Fuss, I. J., Kitani, A. & Strober, W. (2010). NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway. J Clin Invest 120, 1645–1662.
    • (2010) J Clin Invest , vol.120 , pp. 1645-1662
    • Watanabe, T.1    Asano, N.2    Fichtner-Feigl, S.3    Gorelick, P.L.4    Tsuji, Y.5    Matsumoto, Y.6    Chiba, T.7    Fuss, I.J.8    Kitani, A.9    Strober, W.10
  • 99
    • 80053326033 scopus 로고    scopus 로고
    • Activation of type I IFN signaling by NOD1 mediates mucosal host defense against Helicobacter pylori infection
    • Watanabe, T., Asano, N., Kitani, A., Fuss, I. J., Chiba, T. & Strober, W. (2011). Activation of type I IFN signaling by NOD1 mediates mucosal host defense against Helicobacter pylori infection. Gut Microbes 2, 61–65.
    • (2011) Gut Microbes , vol.2 , pp. 61-65
    • Watanabe, T.1    Asano, N.2    Kitani, A.3    Fuss, I.J.4    Chiba, T.5    Strober, W.6
  • 100
    • 84896691062 scopus 로고    scopus 로고
    • NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion
    • Wlodarska, M., Thaiss, C. A., Nowarski, R., Henao-Mejia, J., Zhang, J. P., Brown, E. M., Frankel, G., Levy, M., Katz, M. N. & other authors (2014). NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion. Cell 156, 1045–1059.
    • (2014) Cell , vol.156 , pp. 1045-1059
    • Wlodarska, M.1    Thaiss, C.A.2    Nowarski, R.3    Henao-Mejia, J.4    Zhang, J.P.5    Brown, E.M.6    Frankel, G.7    Levy, M.8    Katz, M.N.9
  • 101
    • 79959329537 scopus 로고    scopus 로고
    • NLRX1 negatively regulates TLR-induced NF-kB signaling by targeting TRAF6 and IKK
    • Xia, X., Cui, J., Wang, H. Y., Zhu, L., Matsueda, S., Wang, Q., Yang, X., Hong, J., Songyang, Z. & other authors (2011). NLRX1 negatively regulates TLR-induced NF-kB signaling by targeting TRAF6 and IKK. Immunity 34, 843–853.
    • (2011) Immunity , vol.34 , pp. 843-853
    • Xia, X.1    Cui, J.2    Wang, H.Y.3    Zhu, L.4    Matsueda, S.5    Wang, Q.6    Yang, X.7    Hong, J.8    Songyang, Z.9
  • 102
    • 0032974805 scopus 로고    scopus 로고
    • Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogenactivated protein kinase signaling pathway
    • Yang, X. & Gabuzda, D. (1999). Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogenactivated protein kinase signaling pathway. J Virol 73, 3460–3466.
    • (1999) J Virol , vol.73 , pp. 3460-3466
    • Yang, X.1    Gabuzda, D.2
  • 103
    • 39149116674 scopus 로고    scopus 로고
    • NLR, the nucleotide-binding domain leucinerich repeat containing gene family
    • Ye, Z. & Ting, J. P. (2008). NLR, the nucleotide-binding domain leucinerich repeat containing gene family. Curr Opin Immunol 20, 3–9.
    • (2008) Curr Opin Immunol , vol.20 , pp. 3-9
    • Ye, Z.1    Ting, J.P.2
  • 106
    • 84891906749 scopus 로고    scopus 로고
    • Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection
    • Zaki, M. H., Man, S. M., Vogel, P., Lamkanfi, M. & Kanneganti, T. D. (2014). Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection. Proc Natl Acad Sci U S A 111, 385–390.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 385-390
    • Zaki, M.H.1    Man, S.M.2    Vogel, P.3    Lamkanfi, M.4    Kanneganti, T.D.5
  • 107
    • 84896344782 scopus 로고    scopus 로고
    • NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING
    • Zhang, L., Mo, J., Swanson, K. V., Wen, H., Petrucelli, A., Gregory, S. M., Zhang, Z., Schneider, M., Jiang, Y. & other authors (2014). NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING. Immunity 40, 329–341.
    • (2014) Immunity , vol.40 , pp. 329-341
    • Zhang, L.1    Mo, J.2    Swanson, K.V.3    Wen, H.4    Petrucelli, A.5    Gregory, S.M.6    Zhang, Z.7    Schneider, M.8    Jiang, Y.9
  • 108
    • 15044359246 scopus 로고    scopus 로고
    • Hepatitis C virus E2 protein promotes human hepatoma cell proliferation through the MAPK/ERK signaling pathway via cellular receptors
    • Zhao, L. J., Wang, L., Ren, H., Cao, J., Li, L., Ke, J. S. & Qi, Z. T. (2005). Hepatitis C virus E2 protein promotes human hepatoma cell proliferation through the MAPK/ERK signaling pathway via cellular receptors. Exp Cell Res 305, 23–32.
    • (2005) Exp Cell Res , vol.305 , pp. 23-32
    • Zhao, L.J.1    Wang, L.2    Ren, H.3    Cao, J.4    Li, L.5    Ke, J.S.6    Qi, Z.T.7
  • 109
    • 33748880164 scopus 로고    scopus 로고
    • Up-regulation of ERK and p38 MAPK signaling pathways by hepatitis C virus E2 envelope protein in human T lymphoma cell line
    • Zhao, L. J., Zhang, X. L., Zhao, P., Cao, J., Cao, M. M., Zhu, S. Y., Liu, H. Q. & Qi, Z. T. (2006). Up-regulation of ERK and p38 MAPK signaling pathways by hepatitis C virus E2 envelope protein in human T lymphoma cell line. J Leukoc Biol 80, 424–432.
    • (2006) J Leukoc Biol , vol.80 , pp. 424-432
    • Zhao, L.J.1    Zhang, X.L.2    Zhao, P.3    Cao, J.4    Cao, M.M.5    Zhu, S.Y.6    Liu, H.Q.7    Qi, Z.T.8
  • 110
    • 84879507094 scopus 로고    scopus 로고
    • ERK signaling is triggered by hepatitis C virus E2 protein through DC-SIGN
    • Zhao, L. J., Wang, W., Ren, H. & Qi, Z. T. (2013). ERK signaling is triggered by hepatitis C virus E2 protein through DC-SIGN. Cell Stress Chaperones 18, 495–501.
    • (2013) Cell Stress Chaperones , vol.18 , pp. 495-501
    • Zhao, L.J.1    Wang, W.2    Ren, H.3    Qi, Z.T.4


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