CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function

Journal of Biological Chemistry

Volumn 280, Issue 18, 2005, Pages 18375-18385

  Conti, Brian J ^a   Davis, Beckley K ^a,b   Zhang, Jinghua ^a   O'Connor Jr , William ^a   Williams, Kristi L ^a   Ting, Jenny P Y ^a,c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b Crohn and Colitis Foundation of America   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATERPILLER 16.2; IMMUNE REGULATORY FUNCTIONS; IONOMYCIN; T CELL ACTIVATION;

ANTIBODIES; CLONING; DISEASES; LIVING SYSTEMS STUDIES; PROTEINS;

CELLS;

GENE PRODUCT; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; IONOMYCIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD28; MONOCLONAL ANTIBODY CD3; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN CLR16.2; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; CARD15 PROTEIN, HUMAN; CARRIER PROTEIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CATERPILLER 16.2 PROTEIN, HUMAN; LRRC1 PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; NUBP1 PROTEIN, HUMAN; PEPTIDE FRAGMENT; SIGNAL PEPTIDE;

ARTICLE; CATERPILLER GENE; CHROMOSOME 16; CLONAL ANERGY; CLR16.2 GENE; CONTROLLED STUDY; GENE; GENE INDUCTION; HUMAN; HUMAN CELL; IMMUNOREGULATION; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN LOCALIZATION; REGULATORY MECHANISM; REPORTER GENE; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; AMINO ACID SEQUENCE; DNA MICROARRAY; DOWN REGULATION; GENETICS; HELA CELL; IMMUNOLOGY; ISOLATION AND PURIFICATION; LEUKEMIA CELL LINE; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MULTIGENE FAMILY; PHYSIOLOGY;

MAMMALIA;

AMINO ACID SEQUENCE; CARRIER PROTEINS; CLONING, MOLECULAR; DOWN-REGULATION; HELA CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NOD2 SIGNALING ADAPTOR PROTEIN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDE FRAGMENTS; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 24044515544     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413169200     Document Type: Article

References (68)

1. Nurnberger, T., and Brunner, F. (2002) Curr. Opin. Plant Biol. 5, 318-324
2. Young, N. D. (2000) Curr. Opin. Plant Biol. 3, 285-290
3. Harton, J. A., Linhoff, M. W., Zhang, J., and Ting, J. P. (2002) J. Immunol. 169, 4088-4093
4. Inohara, N., and Nunez, G. (2003) Nat. Rev. Immunol. 3, 371-382
5. Tschopp, J., Martinon, F., and Burns, K. (2003) Nat. Rev. Mol. Cell. Biol. 4, 95-104
6. Pawlowski, K., Pio, F., Chu, Z., Reed, J. C., and Godzik, A. (2001) Trends Biochem. Sci. 26, 85-87
7. Harton, J. A., and Ting, J. P. (2000) Mol. Cell. Biol. 20, 6185-6194
8. Ting, J. P., and Trowsdale, J. (2002) Cell 109, S21-S33
9. Steimle, V., Otten, L. A., Zufferey, M., and Mach, B. (1993) Cell 75, 135-146
10. Reith, W., and Mach, B. (2001) Annu. Rev. Immunol. 19, 331-373
11. Wong, A. W., Brickey, W. J., Taxman, D. J., van Deventer, H. W., Reed, W., Gao, J. X., Zheng, P., Liu, Y., Li, P., Blum, J. S., McKinnon, K. P., and Ting, J. P. (2003) Nat. Immunol. 4, 891-898
12. Aksentijevich, I., Nowak, M., Mallah, M., Chae, J. J., Watford, W. T., Hofmann, S. R., Stein, L., Russo, R., Goldsmith, D., Dent, P., Rosenberg, H. F., Austin, F., Remmers, E. F., Balow, J. E., Jr., Rosenzweig, S., Komarow, H., Shoham, N. G., Wood, G., Jones, J., Mangra, N., Carrero, H., Adams, B. S., Moore, T. L., Schikler, K., Hoffman, H., Lovell, D. J., Lipnick, R., Barron, K., O'Shea, J. J., Kastner, D. L., and Goldbach-Mansky, R. (2002) Arthritis Rheum. 46, 3340-3348
13. Dode, C., Le Du, N., Cuisset, L., Letourneur, F., Berthelot, J. M., Vaudour, G., Meyrier, A., Watts, R. A., Scott, D. G., Nicholls, A., Granel, B., Frances, C., Garder, F., Edery, P., Boulinguez, S., Domergues, J. P., Delpech, M., and Grateau, G. (2002) Am. J. Hum. Genet. 70, 1498-1506
14. Hoffman, H. M., Mueller, J. L., Broide, D. H., Wanderer, A. A., and Kolodner, R. D. (2001) Nat. Genet. 29, 301-305
15. Neven, B., Callebaut, I., Prieur, A. M., Feldmann, J., Bodemer, C., Lepore, L., Derfalvi, B., Benjaponpitak, S., Vesely, R., Sauvain, M. J., Oertle, S., Allen, R., Morgan, G., Borkhardt, A., Hill, C., Gardner-Medwin, J., Fischer, A., and De Saint Basile, G. (2004) Blood 103, 2809-2815
16. Grenier, J. M., Wang, L., Manji, G. A., Huang, W. J., Al-Garawi, A., Kelly, R., Carlson, A., Merriam, S., Lora, J. M., Briskin, M., DiStefano, P. S., and Bertin, J. (2002) FEBS Lett. 530, 73-78
17. Dowds, T. A., Masumoto, J., Zhu, L., Inohara, N., and Nunez, G. (2004) J. Biol. Chem.
18. Masumoto, J., Taniguchi, S., Ayukawa, K., Sarvotham, H., Kishino, T., Niikawa, N., Hidaka, E., Katsuyama, T., Higuchi, T., and Sagara, J. (1999) J. Biol. Chem. 274, 33835-33838
19. Agostini, L., Martinon, F., Burns, K., McDermott, M. F., Hawkins, P. N., and Tschopp, J. (2004) Immunity 20, 319-325
20. Srinivasula, S. M., Poyet, J. L., Razmara, M., Datta, P., Zhang, Z., and Alnemri, E. S. (2002) J. Biol. Chem. 277, 21119-21122
21. Martinon, F., Burns, K., and Tschopp, J. (2002) Mol. Cell 10, 417-426
22. Manji, G. A., Wang, L., Geddes, B. J., Brown, M., Merriam, S., Al-Garawi, A., Mak, S., Lora, J. M., Briskin, M., Jurman, M., Cao, J., DiStefano, P. S., and Bertin, J. (2002) J. Biol. Chem. 277, 11570-11575
23. Dowds, T. A., Masumoto, J., Chen, F. F., Ogura, Y., Inohara, N., and Nunez, G. (2003) Biochem. Biophys. Res. Commun. 302, 575-580
24. O'Connor, W., Jr., Harton, J. A., Zhu, X., Linhoff, M. W., and Ting, J. P. (2003) J. Immunol. 171, 6329-6333
25. Wang, L., Manji, G. A., Grenier, J. M., Al-Garawi, A., Merriam, S., Lora, J. M., Geddes, B. J., Briskin, M., DiStefano, P. S., and Bertin, J. (2002) J. Biol. Chem. 277, 29874-29880
26. Williams, K. L., Taxman, D. J., Linhoff, M. W., Reed, W., and Ting, J. P. (2003) J. Immunol. 170, 5354-5358
27. Hugot, J. P., Chamaillard, M., Zouali, H., Lesage, S., Cezard, J. P., Belaiche, J., Almer, S., Tysk, C., O'Morain, C. A., Gassull, M., Binder, V., Finkel, Y., Cortot, A., Modigliani, R., Laurent-Puig, P., Gower-Rousseau, C., Macry, J., Colombel, J. F., Sahbatou, M., and Thomas, G. (2001) Nature 411, 599-603
28. Miceli-Richard, C., Lesage, S., Rybojad, M., Prieur, A. M., Manouvrier-Hanu, S., Hafner, R., Chamaillard, M., Zouali, H., Thomas, G., and Hugot, J. P. (2001) Nat. Genet. 29, 19-20
29. Ogura, Y., Bonen, D. K., Inohara, N., Nicolae, D. L., Chen, F. F., Ramos, R., Britton, H., Moran, T., Karaliuskas, R., Duerr, R. H., Achkar, J. P., Brant, S. R., Bayless, T. M., Kirschner, B. S., Hanauer, S. E., Nunez, G., and Cho, J. H. (2001) Nature 411, 603-606
30. Hampe, J., Frenzel, H., Mirza, M. M., Croucher, P. J., Cuthbert, A., Mascheretti, S., Huse, K., Platzer, M., Bridger, S., Meyer, B., Nurnberg, P., Stokkers, P., Krawczak, M., Mathew, C. G., Curran, M., and Schreiber, S. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 321-326
31. Chamaillard, M., Hashimoto, M., Horie, Y., Masumoto, J., Qiu, S., Saab, L., Ogura, Y., Kawasaki, A., Fukase, K., Kusumoto, S., Valvano, M. A., Foster, S. J., Mak, T. W., Nunez, G., and Inohara, N. (2003) Nat. Immunol. 4, 702-707
32. Girardin, S. E., Boneca, I. G., Carneiro, L. A., Antignac, A., Jehanno, M., Viala, J., Tedin, K., Taha, M. K., Labigne, A., Zahringer, U., Coyle, A. J., DiStefano, P. S., Bertin, J., Sansonetti, P. J., and Philpott, D. J. (2003) Science 300, 1584-1587
33. Girardin, S. E., Travassos, L. H., Herve, M., Blanot, D., Boneca, I. G., Philpott, D. J., Sansonetti, P. J., and Mengin-Lecreulx, D. (2003) J. Biol. Chem. 278, 41702-41708
34. Inohara, N., Ogura, Y., Fontalba, A., Gutierrez, O., Pons, F., Crespo, J., Fukase, K., Inamura, S., Kusumoto, S., Hashimoto, M., Foster, S. J., Moran, A. P., Fernandez-Luna, J. L., and Nunez, G. (2003) J. Biol. Chem. 278, 5509-5512
35. Kobayashi, K. S., Eynon, E. E., and Flavell, R. A. (2003) Nat. Immunol. 4, 652-654
36. Beutler, B. (2001) Immunity 15, 5-14
37. Bouma, G., and Strober, W. (2003) Nat. Rev. Immunol. 3, 521-533
38. Girardin, S. E., Hugot, J. P., and Sansonetti, P. J. (2003) Trends Immunol. 24, 652-658
39. Cressman, D. E., O'Connor, W. J., Greer, S. F., Zhu, X. S., and Ting, J. P. (2001) J. Immunol. 167, 3626-3634
40. Su, A. I., Wiltshire, T., Batalov, S., Lapp, H., Ching, K. A., Block, D., Zhang, J., Soden, R., Hayakawa, M., Kreiman, G., Cooke, M. P., Walker, J. R., and Hogenesch, J. B. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 6062-6067
41. Su, A. I., Cooke, M. P., Ching, K. A., Hakak, Y., Walker, J. R., Wiltshire, T., Orth, A. P., Vega, R. G., Sapinoso, L. M., Moqrich, A., Patapoutian, A., Hampton, G. M., Schultz, P. G., and Hogenesch, J. B. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 4465-4470
42. Gollub, J., Ball, C. A., Binkley, G., Demeter, J., Finkelstein, D. B., Hebert, J. M., Hernandez-Boussard, T., Jin, H., Kaloper, M., Matese, J. C., Schroeder, M., Brown, P. O., Botstein, D., and Sherlock, G. (2003) Nucleic Acids Res. 31, 94-96
43. Diehn, M., Alizadeh, A. A., Rando, O. J., Liu, C. L., Stankunas, K., Botstein, D., Crabtree, G. R., and Brown, P. O. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 11796-11801
44. Diehn, M., Sherlock, G., Binkley, G., Jin, H., Matese, J. C., Hernandez-Boussard, T., Rees, C. A., Cherry, J. M., Botstein, D., Brown, P. O., and Alizadeh, A. A. (2003) Nucleic Acids Res. 31, 219-223
45. Boldrick, J. C., Alizadeh, A. A., Diehn, M., Dudoit, S., Liu, C. L., Belcher, C. E., Botstein, D., Staudt, L. M., Brown, P. O., and Relman, D. A. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 972-977
46. Galfalvy, H. C., Erraji-Benchekroun, L., Smyrniotopoulos, P., Pavlidis, P., Ellis, S. P., Mann, J. J., Sibille, E., and Arango, V. (2003) BMC Bioinformatics 4, 37
47. Huang, S., Wang, Y., Chen, P., Qian, H. R., Yeo, A., and Bemis, K. (2004) Genomics 84, 767-777
48. Li, J., Spletter, M. L., and Johnson, J. A. (2005) Physiol. Genomics, in press
49. Wolff, B., Sanglier, J. J., and Wang, Y. (1997) Chem. Biol. 4, 139-147
50. Kudo, N., Wolff, B., Sekimoto, T., Schreiner, E. P., Yoneda, Y., Yanagida, M., Horinouchi, S., and Yoshida, M. (1998) Exp. Cell Res. 242, 540-547
51. Ossareh-Nazari, B., Bachelerie, F., and Dargemont, C. (1997) Science 278, 141-144
52. Huang, T. T., Kudo, N., Yoshida, M., and Miyamoto, S. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 1014-1019
53. Weiss, A., Imboden, J., Hardy, K., Manger, B., Terhorst, C., and Stobo, J. (1986) Annu. Rev. Immunol. 4, 593-619
54. Hollander, G. A. (1999) Semin. Immunol. 11, 357-367
55. Lin, J. X., and Leonard, W. J. (1997) Cytokine Growth Factor Rev. 8, 313-332
56. Kim, H. P., and Leonard, W. J. (2002) EMBO J. 21, 3051-3059
57. Walker, J. E., Saraste, M., Runswick, M. J., and Gay, N. J. (1982) EMBO J. 1, 945-951
58. Kobe, B., and Deisenhofer, J. (1993) Nature 366, 751-756
59. Hillig, R. C., Renault, L., Vetter, I. R., Drell, T. T., Wittinghofer, A., and Becker, J. (1999) Mol. Cell 3, 781-791
60. Linhoff, M. W., Harton, J. A., Cressman, D. E., Martin, B. K., and Ting, J. P. (2001) Mol. Cell. Biol. 21, 3001-3011
61. Inohara, N., Koseki, T., del Peso, L., Hu, Y., Yee, C., Chen, S., Carrio, R., Merino, J., Liu, D., Ni, J., and Nunez, G. (1999) J. Biol. Chem. 274, 14560-14567
62. Ogura, Y., Inohara, N., Benito, A., Chen, F. F., Yamaoka, S., and Nunez, G. (2001) J. Biol. Chem. 276, 4812-4818
63. Karin, M., and Lin, A. (2002) Nat. Immunol. 3, 221-227
64. Li, Q., and Verma, I. M. (2002) Nat. Rev. Immunol. 2, 725-734
65. Ghosh, S., and Karin, M. (2002) Cell 109, S81-S96
66. Nel, A. E., and Slaughter, N. (2002) J. Allergy Clin. Immunol. 109, 901-915
67. Lord, G. M., Lechler, R. I., and George, A. J. (1999) Immunol Today 20, 33-39
68. Sloan-Lancaster, J., and Allen, P. M. (1996) Annu. Rev. Immunol. 14, 1-27