Suppression of NLRX1 in chronic obstructive pulmonary disease

Journal of Clinical Investigation

Volumn 125, Issue 6, 2015, Pages 2458-2462

  Kang, Min Jong ^a,b   Yoon, Chang Min ^a   Kim, Bo Hye ^a   Lee, Chang Min ^b   Zhou, Yang ^b   Sauler, Maor ^a   Homer, Rober ^a,c   Dhamija, Anish ^a   Boffa, Daniel ^a   West, Andrew Phillip ^c   Shadel, Gerald S ^c   Ting, Jenny P ^d   Tedrow, John R ^e   Kaminski, Naftali ^a   Kim, Woo Jin ^f   Lee, Chun Geun ^b   Oh, Yeon Mok ^g   Elias, Jack A ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BROWN UNIVERSITY   (United States)

^c and Genetics ^*  (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^f Kangwon National University   (South Korea)

^g University of Ulsan College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CIGARETTE SMOKE; CXCL13 CHEMOKINE; HELICASE; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MAVS RIG I LIKE HELICASE; NUCLEOTIDE BINDING DOMAIN AND LEUCINE RICH REPEAT CONTAINING PROTEIN X1; NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; DDX58 PROTEIN, HUMAN; DDX58 PROTEIN, MOUSE; DEAD BOX PROTEIN; IPS-1 PROTEIN, MOUSE; MITOCHONDRIAL PROTEIN; NLRX1 PROTEIN, HUMAN; NLRX1 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; VISA PROTEIN, HUMAN;

AIRWAY OBSTRUCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CYTOKINE RESPONSE; DISEASE SEVERITY; DYSPNEA; ENZYME ACTIVATION; ENZYME INHIBITION; FORCED EXPIRATORY VOLUME; GENE EXPRESSION; HUMAN; INNATE IMMUNITY; LUNG ALVEOLUS MACROPHAGE; LUNG EMPHYSEMA; LUNG FUNCTION; MITOPHAGY; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PNEUMONIA; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; QUALITY OF LIFE; TUNEL ASSAY; ADVERSE EFFECTS; ANIMAL; CLINICAL TRIAL; DISEASE MODEL; FEMALE; GENETICS; LUNG ALVEOLUS; MALE; METABOLISM; PATHOLOGY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SIGNAL TRANSDUCTION; SMOKING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; DEAD-BOX RNA HELICASES; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MALE; MICE; MITOCHONDRIAL PROTEINS; PULMONARY ALVEOLI; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SIGNAL TRANSDUCTION; SMOKING;

EID: 84930387909     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI71747     Document Type: Article

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