메뉴 건너뛰기




Volumn 342, Issue , 2017, Pages 212-231

Developmental changes in serotonin signaling: Implications for early brain function, behavior and adaptation

Author keywords

5 HT; epigenetics; fetal development; maternal depression; neurodevelopment; SSRI exposure

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); ANTIDEPRESSANT AGENT; DOPAMINE; GLUCOCORTICOID RECEPTOR; NORADRENALIN; REELIN; SEROTONIN; SEROTONIN 1 RECEPTOR; SEROTONIN RECEPTOR; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR;

EID: 84962265116     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2016.02.037     Document Type: Review
Times cited : (184)

References (219)
  • 2
    • 0035729575 scopus 로고    scopus 로고
    • The effects of maternal depression on fetal heart rate response to vibroacoustic stimulation
    • Allister, L., Lester, B.M., Carr, S., Liu, J., The effects of maternal depression on fetal heart rate response to vibroacoustic stimulation. Dev Neuropsychol 20 (2001), 639–651.
    • (2001) Dev Neuropsychol , vol.20 , pp. 639-651
    • Allister, L.1    Lester, B.M.2    Carr, S.3    Liu, J.4
  • 5
    • 7444232259 scopus 로고    scopus 로고
    • Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice
    • Ansorge, M.S., Zhou, M., Lira, A., Hen, R., Gingrich, J.A., Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science 306 (2004), 879–881.
    • (2004) Science , vol.306 , pp. 879-881
    • Ansorge, M.S.1    Zhou, M.2    Lira, A.3    Hen, R.4    Gingrich, J.A.5
  • 6
    • 38149041752 scopus 로고    scopus 로고
    • Inhibition of serotonin but not norepinephrine transport during development produces delayed, persistent perturbations of emotional behaviors in mice
    • Ansorge, M.S., Morelli, E., Gingrich, J.A., Inhibition of serotonin but not norepinephrine transport during development produces delayed, persistent perturbations of emotional behaviors in mice. J Neurosci 28 (2008), 199–207.
    • (2008) J Neurosci , vol.28 , pp. 199-207
    • Ansorge, M.S.1    Morelli, E.2    Gingrich, J.A.3
  • 7
    • 0035891886 scopus 로고    scopus 로고
    • Modern views on an ancient chemical: serotonin effects on cell proliferation, maturation, and apoptosis
    • Azmitia, E.C., Modern views on an ancient chemical: serotonin effects on cell proliferation, maturation, and apoptosis. Brain Res Bull 56 (2001), 413–424.
    • (2001) Brain Res Bull , vol.56 , pp. 413-424
    • Azmitia, E.C.1
  • 8
    • 33845917359 scopus 로고    scopus 로고
    • Developmental and behavioral consequences of prenatal fluoxetine
    • Bairy, K.L., Madhyastha, S., Ashok, K.P., Bairy, I., Malini, S., Developmental and behavioral consequences of prenatal fluoxetine. Pharmacology 79 (2007), 1–11.
    • (2007) Pharmacology , vol.79 , pp. 1-11
    • Bairy, K.L.1    Madhyastha, S.2    Ashok, K.P.3    Bairy, I.4    Malini, S.5
  • 9
    • 1642331289 scopus 로고    scopus 로고
    • Serotonin-induced increases in adult cell proliferation and neurogenesis are mediated through different and common 5-HT receptor subtypes in the dentate gyrus and the subventricular zone
    • Banasr, M., Hery, M., Printemps, R., Daszuta, A., Serotonin-induced increases in adult cell proliferation and neurogenesis are mediated through different and common 5-HT receptor subtypes in the dentate gyrus and the subventricular zone. Neuropsychopharmacology 29 (2004), 450–460.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 450-460
    • Banasr, M.1    Hery, M.2    Printemps, R.3    Daszuta, A.4
  • 10
    • 0028814094 scopus 로고
    • Do antidepressants stabilize mood through actions on the hypothalamic-pituitary–adrenocortical system?
    • Barden, N., Reul, J.M., Holsboer, F., Do antidepressants stabilize mood through actions on the hypothalamic-pituitary–adrenocortical system?. Trends Neurosci 18 (1995), 6–11.
    • (1995) Trends Neurosci , vol.18 , pp. 6-11
    • Barden, N.1    Reul, J.M.2    Holsboer, F.3
  • 11
    • 0029418480 scopus 로고
    • Intrauterine programming of adult disease
    • Barker, D.J., Intrauterine programming of adult disease. Mol Med Today 1 (1995), 418–423.
    • (1995) Mol Med Today , vol.1 , pp. 418-423
    • Barker, D.J.1
  • 13
    • 70449469454 scopus 로고    scopus 로고
    • Beyond diathesis stress: differential susceptibility to environmental influences
    • Belsky, J., Pluess, M., Beyond diathesis stress: differential susceptibility to environmental influences. Psychol Bull 135 (2009), 885–908.
    • (2009) Psychol Bull , vol.135 , pp. 885-908
    • Belsky, J.1    Pluess, M.2
  • 14
    • 84859917093 scopus 로고    scopus 로고
    • Sertraline alters multidrug resistance phosphoglycoprotein activity in the mouse placenta and fetal blood–brain barrier
    • Bhuiyan, M., Petropoulos, S., Gibb, W., Matthews, S.G., Sertraline alters multidrug resistance phosphoglycoprotein activity in the mouse placenta and fetal blood–brain barrier. Reprod Sci 19 (2012), 407–415.
    • (2012) Reprod Sci , vol.19 , pp. 407-415
    • Bhuiyan, M.1    Petropoulos, S.2    Gibb, W.3    Matthews, S.G.4
  • 15
    • 0029018317 scopus 로고
    • Effectiveness of pindolol with selected antidepressant drugs in the treatment of major depression
    • Blier, P., Bergeron, R., Effectiveness of pindolol with selected antidepressant drugs in the treatment of major depression. J Clin Psychopharmacol 15 (1995), 217–222.
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 217-222
    • Blier, P.1    Bergeron, R.2
  • 16
    • 82855166035 scopus 로고    scopus 로고
    • Fetal, maternal, and placental sources of serotonin and new implications for developmental programming of the brain
    • Bonnin, A., Levitt, P., Fetal, maternal, and placental sources of serotonin and new implications for developmental programming of the brain. Neuroscience 197 (2011), 1–7.
    • (2011) Neuroscience , vol.197 , pp. 1-7
    • Bonnin, A.1    Levitt, P.2
  • 17
    • 84856103591 scopus 로고    scopus 로고
    • Placental source for 5-HT that tunes fetal brain development
    • Bonnin, A., Levitt, P., Placental source for 5-HT that tunes fetal brain development. Neuropsychopharmacology 37 (2012), 299–300.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 299-300
    • Bonnin, A.1    Levitt, P.2
  • 18
    • 34247514888 scopus 로고    scopus 로고
    • Serotonin modulates the response of embryonic thalamocortical axons to netrin-1
    • Bonnin, A., Torii, M., Wang, L., Rakic, P., Levitt, P., Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nat Neurosci 10 (2007), 588–597.
    • (2007) Nat Neurosci , vol.10 , pp. 588-597
    • Bonnin, A.1    Torii, M.2    Wang, L.3    Rakic, P.4    Levitt, P.5
  • 20
    • 84874508475 scopus 로고    scopus 로고
    • Looking beyond the DNA sequence: the relevance of DNA methylation processes for the stress-diathesis model of depression
    • Booij, L., Wang, D., Levesque, M.L., Tremblay, R.E., Szyf, M., Looking beyond the DNA sequence: the relevance of DNA methylation processes for the stress-diathesis model of depression. Philos Trans R Soc Lond B Biol Sci, 368, 2013, 20120251.
    • (2013) Philos Trans R Soc Lond B Biol Sci , vol.368 , pp. 20120251
    • Booij, L.1    Wang, D.2    Levesque, M.L.3    Tremblay, R.E.4    Szyf, M.5
  • 21
    • 84924940418 scopus 로고    scopus 로고
    • DNA methylation of the serotonin transporter gene in peripheral cells and stress-related changes in hippocampal volume: a study in depressed patients and healthy controls
    • Booij, L.M., Carballedo, A., Frey, E.M., Morris, D., Dymov, S., Vaisheva, F., Ly, V., Fahey, C., Meaney, J., Gill, M., Frodl, T., DNA methylation of the serotonin transporter gene in peripheral cells and stress-related changes in hippocampal volume: a study in depressed patients and healthy controls. PLoS One, 10, 2015, e0119061.
    • (2015) PLoS One , vol.10
    • Booij, L.M.1    Carballedo, A.2    Frey, E.M.3    Morris, D.4    Dymov, S.5    Vaisheva, F.6    Ly, V.7    Fahey, C.8    Meaney, J.9    Gill, M.10    Frodl, T.11
  • 22
    • 84920997009 scopus 로고    scopus 로고
    • Genetic and early environmental influences on the serotonin system: consequences for brain development and risk for psychopathology
    • Booij, L., Tremblay, R.E., Szyf, M., Benkelfa, C., Genetic and early environmental influences on the serotonin system: consequences for brain development and risk for psychopathology. J Psychiatry Neurosci 40 (2015), 5–18.
    • (2015) J Psychiatry Neurosci , vol.40 , pp. 5-18
    • Booij, L.1    Tremblay, R.E.2    Szyf, M.3    Benkelfa, C.4
  • 23
    • 84956894014 scopus 로고    scopus 로고
    • Antidepressant use during pregnancy and the risk of autism spectrum disorder in children
    • Boukhris, T., Sheehy, O., Mottron, L., Berard, A., Antidepressant use during pregnancy and the risk of autism spectrum disorder in children. JAMA Pediatr 170:2 (2016), 117–124.
    • (2016) JAMA Pediatr , vol.170 , Issue.2 , pp. 117-124
    • Boukhris, T.1    Sheehy, O.2    Mottron, L.3    Berard, A.4
  • 24
    • 25844470929 scopus 로고    scopus 로고
    • Biological sensitivity to context: I. An evolutionary–developmental theory of the origins and functions of stress reactivity
    • Boyce, W.T., Ellis, B.J., Biological sensitivity to context: I. An evolutionary–developmental theory of the origins and functions of stress reactivity. Dev Psychopathol 17 (2005), 271–301.
    • (2005) Dev Psychopathol , vol.17 , pp. 271-301
    • Boyce, W.T.1    Ellis, B.J.2
  • 25
    • 0033051299 scopus 로고    scopus 로고
    • Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats
    • Brezun, J.M., Daszuta, A., Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats. Neuroscience 89 (1999), 999–1002.
    • (1999) Neuroscience , vol.89 , pp. 999-1002
    • Brezun, J.M.1    Daszuta, A.2
  • 26
    • 0033975945 scopus 로고    scopus 로고
    • Serotonergic reinnervation reverses lesion-induced decreases in PSA-NCAM labeling and proliferation of hippocampal cells in adult rats
    • Brezun, J.M., Daszuta, A., Serotonergic reinnervation reverses lesion-induced decreases in PSA-NCAM labeling and proliferation of hippocampal cells in adult rats. Hippocampus 10 (2000), 37–46.
    • (2000) Hippocampus , vol.10 , pp. 37-46
    • Brezun, J.M.1    Daszuta, A.2
  • 27
    • 33747069945 scopus 로고    scopus 로고
    • High post-partum levels of corticosterone given to dams influence postnatal hippocampal cell proliferation and behavior of offspring: a model of post-partum stress and possible depression
    • Brummelte, S., Pawluski, J.L., Galea, L.A., High post-partum levels of corticosterone given to dams influence postnatal hippocampal cell proliferation and behavior of offspring: a model of post-partum stress and possible depression. Horm Behav 50 (2006), 370–382.
    • (2006) Horm Behav , vol.50 , pp. 370-382
    • Brummelte, S.1    Pawluski, J.L.2    Galea, L.A.3
  • 28
    • 85008386923 scopus 로고    scopus 로고
    • Antidepressant use during pregnancy and serotonin transporter genotype (SLC6A4) Affect newborn serum reelin levels
    • Brummelte, S., Galea, L.A.M., Devlin, A.M., Oberlander, T.F., Antidepressant use during pregnancy and serotonin transporter genotype (SLC6A4) Affect newborn serum reelin levels. Dev Psychobiol, 2012.
    • (2012) Dev Psychobiol
    • Brummelte, S.1    Galea, L.A.M.2    Devlin, A.M.3    Oberlander, T.F.4
  • 29
    • 45749158144 scopus 로고    scopus 로고
    • Psychiatric genetics: progress amid controversy
    • Burmeister, M., McInnis, M.G., Zollner, S., Psychiatric genetics: progress amid controversy. Nat Rev Genet 9 (2008), 527–540.
    • (2008) Nat Rev Genet , vol.9 , pp. 527-540
    • Burmeister, M.1    McInnis, M.G.2    Zollner, S.3
  • 30
    • 0021125503 scopus 로고
    • The action of neurotransmitters and related substances on early embryogenesis
    • Buznikov, G.A., The action of neurotransmitters and related substances on early embryogenesis. Pharmacol Ther 25 (1984), 23–59.
    • (1984) Pharmacol Ther , vol.25 , pp. 23-59
    • Buznikov, G.A.1
  • 32
    • 0030058732 scopus 로고    scopus 로고
    • Lack of barrels in the somatosensory cortex of monoamine oxidase A-deficient mice: role of a serotonin excess during the critical period
    • Cases, O., Vitalis, T., Seif, I., De, M.E., Sotelo, C., Gaspar, P., Lack of barrels in the somatosensory cortex of monoamine oxidase A-deficient mice: role of a serotonin excess during the critical period. Neuron 16 (1996), 297–307.
    • (1996) Neuron , vol.16 , pp. 297-307
    • Cases, O.1    Vitalis, T.2    Seif, I.3    De, M.E.4    Sotelo, C.5    Gaspar, P.6
  • 33
    • 0037399190 scopus 로고    scopus 로고
    • Follow-up of children of depressed mothers exposed or not exposed to antidepressant drugs during pregnancy
    • Casper, R.C., Fleisher, B.E., Lee-Ancajas, J.C., Gilles, A., Gaylor, E., DeBattista, A., Hoyme, H.E., Follow-up of children of depressed mothers exposed or not exposed to antidepressant drugs during pregnancy. J Pediatr 142 (2003), 402–408.
    • (2003) J Pediatr , vol.142 , pp. 402-408
    • Casper, R.C.1    Fleisher, B.E.2    Lee-Ancajas, J.C.3    Gilles, A.4    Gaylor, E.5    DeBattista, A.6    Hoyme, H.E.7
  • 34
    • 33745684557 scopus 로고    scopus 로고
    • Opinion – gene-environment interactions in psychiatry: joining forces with neuroscience
    • Caspi, A., Moffitt, T.E., Opinion – gene-environment interactions in psychiatry: joining forces with neuroscience. Nat Rev Neurosci 7 (2006), 583–590.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 583-590
    • Caspi, A.1    Moffitt, T.E.2
  • 36
    • 65249162798 scopus 로고    scopus 로고
    • The N-terminal region of reelin regulates postnatal dendritic maturation of cortical pyramidal neurons
    • Chameau, P., Inta, D., Vitalis, T., Monyer, H., Wadman, W.J., Van Hooft, J.A., The N-terminal region of reelin regulates postnatal dendritic maturation of cortical pyramidal neurons. Proc Natl Acad Sci U S A 106 (2009), 7227–7232.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 7227-7232
    • Chameau, P.1    Inta, D.2    Vitalis, T.3    Monyer, H.4    Wadman, W.J.5    Van Hooft, J.A.6
  • 38
    • 2442673159 scopus 로고    scopus 로고
    • Life stress, genes, and depression: multiple pathways lead to increased risk and new opportunities for intervention
    • Charney, D.S., Manji, H.K., Life stress, genes, and depression: multiple pathways lead to increased risk and new opportunities for intervention. Sci STKE, 2004, 2004, re5.
    • (2004) Sci STKE , vol.2004 , pp. re5
    • Charney, D.S.1    Manji, H.K.2
  • 39
    • 0033940092 scopus 로고    scopus 로고
    • The role of stress and the hypothalamic-pituitary–adrenal axis in the pathogenesis of the metabolic syndrome: neuro-endocrine and target tissue-related causes
    • Chrousos, G.P., The role of stress and the hypothalamic-pituitary–adrenal axis in the pathogenesis of the metabolic syndrome: neuro-endocrine and target tissue-related causes. Int J Obes Relat Metab Disord 24:Suppl 2 (2000), S50–S55.
    • (2000) Int J Obes Relat Metab Disord , vol.24 , pp. S50-S55
    • Chrousos, G.P.1
  • 44
    • 3042760446 scopus 로고    scopus 로고
    • Sex-specific development of cortical monoamine levels in mouse
    • Connell, S., Karikari, C., Hohmann, C.F., Sex-specific development of cortical monoamine levels in mouse. Brain Res Dev Brain Res 151 (2004), 187–191.
    • (2004) Brain Res Dev Brain Res , vol.151 , pp. 187-191
    • Connell, S.1    Karikari, C.2    Hohmann, C.F.3
  • 46
    • 80051631127 scopus 로고    scopus 로고
    • Antidepressant use during pregnancy and childhood autism spectrum disorders
    • Croen, L.A., Grether, J.K., Yoshida, C.K., Odouli, R., Hendrick, V., Antidepressant use during pregnancy and childhood autism spectrum disorders. Arch Gen Psychiatry 68 (2011), 1104–1112.
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 1104-1112
    • Croen, L.A.1    Grether, J.K.2    Yoshida, C.K.3    Odouli, R.4    Hendrick, V.5
  • 48
    • 0025615031 scopus 로고
    • Modification of serotonergic neuron properties by long-term treatment with serotonin reuptake blockers
    • DE Montigny, C., Chaput, Y., Blier, P., Modification of serotonergic neuron properties by long-term treatment with serotonin reuptake blockers. J Clin Psychiatry 51:Suppl B (1990), 4–8.
    • (1990) J Clin Psychiatry , vol.51 , pp. 4-8
    • DE Montigny, C.1    Chaput, Y.2    Blier, P.3
  • 49
    • 77957880665 scopus 로고    scopus 로고
    • Prenatal exposure to maternal depressed mood and the MTHFR C677T variant affect SLC6A4 methylation in infants at birth
    • Devlin, A.M., Brain, U., Austin, J., Oberlander, T.F., Prenatal exposure to maternal depressed mood and the MTHFR C677T variant affect SLC6A4 methylation in infants at birth. PLoS One, 5, 2010, e12201.
    • (2010) PLoS One , vol.5 , pp. e12201
    • Devlin, A.M.1    Brain, U.2    Austin, J.3    Oberlander, T.F.4
  • 52
    • 84876814627 scopus 로고    scopus 로고
    • Paying attention to all results, positive and negative
    • Duncan, L.E., Paying attention to all results, positive and negative. J Am Acad Child Adolesc Psychiatry 52 (2013), 462–465.
    • (2013) J Am Acad Child Adolesc Psychiatry , vol.52 , pp. 462-465
    • Duncan, L.E.1
  • 55
    • 84872942417 scopus 로고    scopus 로고
    • Epigenetic vestiges of early developmental adversity: childhood stress exposure and DNA methylation in adolescence
    • Essex, M.J., Boyce, W.T., Hertzman, C., Lam, L.L., Armstrong, J.M., Neumann, S.M., Kobor, M.S., Epigenetic vestiges of early developmental adversity: childhood stress exposure and DNA methylation in adolescence. Child Dev 84 (2013), 58–75.
    • (2013) Child Dev , vol.84 , pp. 58-75
    • Essex, M.J.1    Boyce, W.T.2    Hertzman, C.3    Lam, L.L.4    Armstrong, J.M.5    Neumann, S.M.6    Kobor, M.S.7
  • 59
    • 30344484828 scopus 로고    scopus 로고
    • Evidence for a gene-environment interaction in predicting behavioral inhibition in middle childhood
    • Fox, N.A., Nichols, K.E., Henderson, H.A., Rubin, K., Schmidt, L., Hamer, D., Ernst, M., Pine, D.S., Evidence for a gene-environment interaction in predicting behavioral inhibition in middle childhood. Psychol Sci 16 (2005), 921–926.
    • (2005) Psychol Sci , vol.16 , pp. 921-926
    • Fox, N.A.1    Nichols, K.E.2    Henderson, H.A.3    Rubin, K.4    Schmidt, L.5    Hamer, D.6    Ernst, M.7    Pine, D.S.8
  • 60
    • 66149177049 scopus 로고    scopus 로고
    • Looking on the bright side: biased attention and the human serotonin transporter gene
    • Fox, E., Ridgewell, A., Ashwin, C., Looking on the bright side: biased attention and the human serotonin transporter gene. Proc Biol Sci 276 (2009), 1747–1751.
    • (2009) Proc Biol Sci , vol.276 , pp. 1747-1751
    • Fox, E.1    Ridgewell, A.2    Ashwin, C.3
  • 62
    • 0029970063 scopus 로고    scopus 로고
    • Mechanisms and functions of serotonin neuronal systems: opportunities for neuropeptide interactions
    • Fuller, R.W., Mechanisms and functions of serotonin neuronal systems: opportunities for neuropeptide interactions. Ann NY Acad Sci 780 (1996), 176–184.
    • (1996) Ann NY Acad Sci , vol.780 , pp. 176-184
    • Fuller, R.W.1
  • 63
    • 84937000806 scopus 로고    scopus 로고
    • Child developmental outcomes in preschool children following antidepressant exposure in pregnancy
    • Galbally, M., Lewis, A.J., Buist, A., Child developmental outcomes in preschool children following antidepressant exposure in pregnancy. Aust N Z J Psychiatry 49 (2015), 642–650.
    • (2015) Aust N Z J Psychiatry , vol.49 , pp. 642-650
    • Galbally, M.1    Lewis, A.J.2    Buist, A.3
  • 64
    • 0345258497 scopus 로고    scopus 로고
    • The developmental role of serotonin: news from mouse molecular genetics
    • Gaspar, P., Cases, O., Maroteaux, L., The developmental role of serotonin: news from mouse molecular genetics. Nat Rev Neurosci 4 (2003), 1002–1012.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 1002-1012
    • Gaspar, P.1    Cases, O.2    Maroteaux, L.3
  • 65
    • 84929322302 scopus 로고    scopus 로고
    • Prenatal antidepressant exposure and the risk of autism spectrum disorders in children. Are we looking at the fall of Gods?
    • Gentile, S., Prenatal antidepressant exposure and the risk of autism spectrum disorders in children. Are we looking at the fall of Gods?. J Affect Disord 182 (2015), 132–137.
    • (2015) J Affect Disord , vol.182 , pp. 132-137
    • Gentile, S.1
  • 66
    • 84945369533 scopus 로고    scopus 로고
    • Untreated depression during pregnancy: short- and long-term effects in offspring. A systematic review
    • Gentile, S., Untreated depression during pregnancy: short- and long-term effects in offspring. A systematic review. Neuroscience 342 (2017), 154–166.
    • (2017) Neuroscience , vol.342 , pp. 154-166
    • Gentile, S.1
  • 67
    • 84912027605 scopus 로고    scopus 로고
    • In utero exposure to selective serotonin reuptake inhibitors and risk for autism spectrum disorder
    • Gidaya, N., Lee, B., Burstyn, I., Yudell, M., Mortensen, E., Newschaffer, C., In utero exposure to selective serotonin reuptake inhibitors and risk for autism spectrum disorder. J Autism Dev Disord 44 (2014), 2558–2567.
    • (2014) J Autism Dev Disord , vol.44 , pp. 2558-2567
    • Gidaya, N.1    Lee, B.2    Burstyn, I.3    Yudell, M.4    Mortensen, E.5    Newschaffer, C.6
  • 68
    • 0035073901 scopus 로고    scopus 로고
    • Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice
    • Gingrich, J.A., Hen, R., Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice. Psychopharmacology (Berl) 155 (2001), 1–10.
    • (2001) Psychopharmacology (Berl) , vol.155 , pp. 1-10
    • Gingrich, J.A.1    Hen, R.2
  • 70
    • 79952683347 scopus 로고    scopus 로고
    • Annual research review: prenatal stress and the origins of psychopathology: an evolutionary perspective
    • Glover, V., Annual research review: prenatal stress and the origins of psychopathology: an evolutionary perspective. J Child Psychol Psychiatry 52 (2011), 356–367.
    • (2011) J Child Psychol Psychiatry , vol.52 , pp. 356-367
    • Glover, V.1
  • 71
    • 24944487171 scopus 로고    scopus 로고
    • Predictive adaptive responses and human evolution
    • Gluckman, P.D., Hanson, M.A., Spencer, H.G., Predictive adaptive responses and human evolution. Trends Ecol Evol 20 (2005), 527–533.
    • (2005) Trends Ecol Evol , vol.20 , pp. 527-533
    • Gluckman, P.D.1    Hanson, M.A.2    Spencer, H.G.3
  • 72
    • 33846058958 scopus 로고    scopus 로고
    • Early life events and their consequences for later disease: a life history and evolutionary perspective
    • Gluckman, P.D., Hanson, M.A., Beedle, A.S., Early life events and their consequences for later disease: a life history and evolutionary perspective. Am J Hum Biol 19 (2007), 1–19.
    • (2007) Am J Hum Biol , vol.19 , pp. 1-19
    • Gluckman, P.D.1    Hanson, M.A.2    Beedle, A.S.3
  • 73
    • 0035122950 scopus 로고    scopus 로고
    • Modifications of the serotonergic system in mice lacking serotonin transporters: an in vivo electrophysiological study
    • Gobbi, G., Murphy, D.L., Lesch, K., Blier, P., Modifications of the serotonergic system in mice lacking serotonin transporters: an in vivo electrophysiological study. J Pharmacol Exp Ther 296 (2001), 987–995.
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 987-995
    • Gobbi, G.1    Murphy, D.L.2    Lesch, K.3    Blier, P.4
  • 74
    • 84865080155 scopus 로고    scopus 로고
    • Neurodevelopmental outcomes following prenatal exposure to serotonin reuptake inhibitor antidepressants: a “social teratogen” or moderator of developmental risk?
    • Hanley, G.E., Oberlander, T.F., Neurodevelopmental outcomes following prenatal exposure to serotonin reuptake inhibitor antidepressants: a “social teratogen” or moderator of developmental risk?. Birth Defects Res A Clin Mol Teratol 94 (2012), 651–659.
    • (2012) Birth Defects Res A Clin Mol Teratol , vol.94 , pp. 651-659
    • Hanley, G.E.1    Oberlander, T.F.2
  • 75
    • 84879839858 scopus 로고    scopus 로고
    • Infant developmental outcomes following prenatal exposure to antidepressants, and maternal depressed mood and positive affect
    • Hanley, G.E., Brain, U., Oberlander, T.F., Infant developmental outcomes following prenatal exposure to antidepressants, and maternal depressed mood and positive affect. Early Hum Dev 89 (2013), 519–524.
    • (2013) Early Hum Dev , vol.89 , pp. 519-524
    • Hanley, G.E.1    Brain, U.2    Oberlander, T.F.3
  • 76
    • 84937543036 scopus 로고    scopus 로고
    • Prenatal exposure to serotonin reuptake inhibitor antidepressants and childhood behavior
    • Hanley, G.E., Brain, U., Oberlander, T.F., Prenatal exposure to serotonin reuptake inhibitor antidepressants and childhood behavior. Pediatr Res 78 (2015), 174–180.
    • (2015) Pediatr Res , vol.78 , pp. 174-180
    • Hanley, G.E.1    Brain, U.2    Oberlander, T.F.3
  • 77
    • 0031473315 scopus 로고    scopus 로고
    • Neonatal administration of the selective serotonin reuptake inhibitor Lu 10–134-C increases forced swimming-induced immobility in adult rats: a putative animal model of depression?
    • Hansen, H.H., Sanchez, C., Meier, E., Neonatal administration of the selective serotonin reuptake inhibitor Lu 10–134-C increases forced swimming-induced immobility in adult rats: a putative animal model of depression?. J Pharmacol Exp Ther 283 (1997), 1333–1341.
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 1333-1341
    • Hansen, H.H.1    Sanchez, C.2    Meier, E.3
  • 78
    • 33645799676 scopus 로고    scopus 로고
    • Genetics of emotional regulation: the role of the serotonin transporter in neural function
    • Hariri, A.R., Holmes, A., Genetics of emotional regulation: the role of the serotonin transporter in neural function. Trends Cogn Sci 10 (2006), 182–191.
    • (2006) Trends Cogn Sci , vol.10 , pp. 182-191
    • Hariri, A.R.1    Holmes, A.2
  • 79
    • 84899789470 scopus 로고    scopus 로고
    • Prenatal SSRI use and offspring with autism spectrum disorder or developmental delay
    • Harrington, R.A., Lee, L.C., Crum, R.M., Zimmerman, A.W., Hertz-Picciotto, I., Prenatal SSRI use and offspring with autism spectrum disorder or developmental delay. Pediatrics 133 (2014), e1241–e1248.
    • (2014) Pediatrics , vol.133 , pp. e1241-e1248
    • Harrington, R.A.1    Lee, L.C.2    Crum, R.M.3    Zimmerman, A.W.4    Hertz-Picciotto, I.5
  • 82
    • 29244461748 scopus 로고    scopus 로고
    • Serotonergic modulation of the limbic system
    • Hensler, J.G., Serotonergic modulation of the limbic system. Neurosci Biobehav Rev 30 (2006), 203–214.
    • (2006) Neurosci Biobehav Rev , vol.30 , pp. 203-214
    • Hensler, J.G.1
  • 83
    • 77952735964 scopus 로고    scopus 로고
    • How experience gets under the skin to create gradients in developmental health
    • Hertzman, C., Boyce, T., How experience gets under the skin to create gradients in developmental health. Annu Rev Public Health 31 (2010), 329–347.
    • (2010) Annu Rev Public Health , vol.31 , pp. 329-347
    • Hertzman, C.1    Boyce, T.2
  • 85
    • 84937042975 scopus 로고    scopus 로고
    • Epigenetic mechanisms of serotonin signaling
    • Holloway, T., Gonzalez-Maeso, J., Epigenetic mechanisms of serotonin signaling. ACS Chem Neurosci 6 (2015), 1099–1109.
    • (2015) ACS Chem Neurosci , vol.6 , pp. 1099-1109
    • Holloway, T.1    Gonzalez-Maeso, J.2
  • 86
    • 0345305849 scopus 로고    scopus 로고
    • Abnormal anxiety-related behaviour in serotonin transporter null mutant mice: the influence of genetic background
    • Holmes, A., Li, Q., Murphy, D.L., Gold, E., Crawley, J.N., Abnormal anxiety-related behaviour in serotonin transporter null mutant mice: the influence of genetic background. Genes Brain Behav 2 (2003), 365–380.
    • (2003) Genes Brain Behav , vol.2 , pp. 365-380
    • Holmes, A.1    Li, Q.2    Murphy, D.L.3    Gold, E.4    Crawley, J.N.5
  • 87
    • 0242391960 scopus 로고    scopus 로고
    • Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression
    • Holmes, A., Murphy, D.L., Crawley, J.N., Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression. Biol Psychiatry 54 (2003), 953–959.
    • (2003) Biol Psychiatry , vol.54 , pp. 953-959
    • Holmes, A.1    Murphy, D.L.2    Crawley, J.N.3
  • 88
    • 70449369613 scopus 로고    scopus 로고
    • Deciphering the interaction of the corticotropin-releasing factor and serotonin brain systems in anxiety-related disorders
    • Homberg, J.R., Contet, C., Deciphering the interaction of the corticotropin-releasing factor and serotonin brain systems in anxiety-related disorders. J Neurosci 29 (2009), 13743–13745.
    • (2009) J Neurosci , vol.29 , pp. 13743-13745
    • Homberg, J.R.1    Contet, C.2
  • 89
    • 79952012111 scopus 로고    scopus 로고
    • Looking on the bright side of serotonin transporter gene variation
    • Homberg, J.R., Lesch, K.P., Looking on the bright side of serotonin transporter gene variation. Biol Psychiatry 69 (2011), 513–519.
    • (2011) Biol Psychiatry , vol.69 , pp. 513-519
    • Homberg, J.R.1    Lesch, K.P.2
  • 90
    • 33751116818 scopus 로고    scopus 로고
    • Blood pressure in mutant rats lacking the 5-hydroxytryptamine transporter
    • Homberg, J., Mudde, J., Braam, B., Ellenbroek, B., Cuppen, E., Joles, J.A., Blood pressure in mutant rats lacking the 5-hydroxytryptamine transporter. Hypertension 48 (2006), e115–e116.
    • (2006) Hypertension , vol.48 , pp. e115-e116
    • Homberg, J.1    Mudde, J.2    Braam, B.3    Ellenbroek, B.4    Cuppen, E.5    Joles, J.A.6
  • 91
    • 75449100367 scopus 로고    scopus 로고
    • New perspectives on the neurodevelopmental effects of SSRIs
    • Homberg, J.R., Schubert, D., Gaspar, P., New perspectives on the neurodevelopmental effects of SSRIs. Trends Pharmacol Sci 31 (2010), 60–65.
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 60-65
    • Homberg, J.R.1    Schubert, D.2    Gaspar, P.3
  • 93
    • 84857433434 scopus 로고    scopus 로고
    • Pre-gestational stress reduces the ratio of 5-HIAA to 5-HT and the expression of 5-HT1A receptor and serotonin transporter in the brain of foetal rat
    • Huang, Y., Xu, H., Li, H., Yang, H., Chen, Y., Shi, X., Pre-gestational stress reduces the ratio of 5-HIAA to 5-HT and the expression of 5-HT1A receptor and serotonin transporter in the brain of foetal rat. BMC Neurosci, 13, 2012, 22.
    • (2012) BMC Neurosci , vol.13 , pp. 22
    • Huang, Y.1    Xu, H.2    Li, H.3    Yang, H.4    Chen, Y.5    Shi, X.6
  • 94
    • 0030848528 scopus 로고    scopus 로고
    • Expression of reelin, the gene responsible for the reeler mutation, in embryonic development and adulthood in the mouse
    • Ikeda, Y., Terashima, T., Expression of reelin, the gene responsible for the reeler mutation, in embryonic development and adulthood in the mouse. Dev Dyn 210 (1997), 157–172.
    • (1997) Dev Dyn , vol.210 , pp. 157-172
    • Ikeda, Y.1    Terashima, T.2
  • 95
    • 84929316335 scopus 로고    scopus 로고
    • Role of the 5-HT4 receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus
    • Imoto, Y., Kira, T., Sukeno, M., Nishitani, N., Nagayasu, K., Nakagawa, T., Kaneko, S., Kobayashi, K., Segi-Nishida, E., Role of the 5-HT4 receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus. Mol Brain, 8, 2015, 29.
    • (2015) Mol Brain , vol.8 , pp. 29
    • Imoto, Y.1    Kira, T.2    Sukeno, M.3    Nishitani, N.4    Nagayasu, K.5    Nakagawa, T.6    Kaneko, S.7    Kobayashi, K.8    Segi-Nishida, E.9
  • 96
    • 20444471528 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitor treatment of early postnatal mice reverses their prenatal stress-induced brain dysfunction
    • Ishiwata, H., Shiga, T., Okado, N., Selective serotonin reuptake inhibitor treatment of early postnatal mice reverses their prenatal stress-induced brain dysfunction. Neuroscience 133 (2005), 893–901.
    • (2005) Neuroscience , vol.133 , pp. 893-901
    • Ishiwata, H.1    Shiga, T.2    Okado, N.3
  • 97
    • 1242319296 scopus 로고    scopus 로고
    • Early serotonergic projections to Cajal-Retzius cells: relevance for cortical development
    • Janusonis, S., Gluncic, V., Rakic, P., Early serotonergic projections to Cajal-Retzius cells: relevance for cortical development. J Neurosci 24 (2004), 1652–1659.
    • (2004) J Neurosci , vol.24 , pp. 1652-1659
    • Janusonis, S.1    Gluncic, V.2    Rakic, P.3
  • 98
    • 72449207509 scopus 로고    scopus 로고
    • Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes
    • Kalueff, A.V., Olivier, J.D., Nonkes, L.J., Homberg, J.R., Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes. Neurosci Biobehav Rev 34 (2010), 373–386.
    • (2010) Neurosci Biobehav Rev , vol.34 , pp. 373-386
    • Kalueff, A.V.1    Olivier, J.D.2    Nonkes, L.J.3    Homberg, J.R.4
  • 100
    • 79952033418 scopus 로고    scopus 로고
    • The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation
    • Karg, K., Burmeister, M., Shedden, K., Sen, S., The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation. Arch Gen Psychiatry 68 (2011), 444–454.
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 444-454
    • Karg, K.1    Burmeister, M.2    Shedden, K.3    Sen, S.4
  • 101
    • 21344449777 scopus 로고    scopus 로고
    • “A gene for...”: the nature of gene action in psychiatric disorders
    • Kendler, K.S., “A gene for...”: the nature of gene action in psychiatric disorders. Am J Psychiatry 162 (2005), 1243–1252.
    • (2005) Am J Psychiatry , vol.162 , pp. 1243-1252
    • Kendler, K.S.1
  • 102
    • 18244389951 scopus 로고    scopus 로고
    • The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication
    • Kendler, K.S., Kuhn, J.W., Vittum, J., Prescott, C.A., Riley, B., The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication. Arch Gen Psychiatry 62 (2005), 529–535.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 529-535
    • Kendler, K.S.1    Kuhn, J.W.2    Vittum, J.3    Prescott, C.A.4    Riley, B.5
  • 104
    • 0037108459 scopus 로고    scopus 로고
    • Serotonin promotes G(o)-dependent neuronal migration in Caenorhabditis elegans
    • Kindt, K.S., Tam, T., Whiteman, S., Schafer, W.R., Serotonin promotes G(o)-dependent neuronal migration in Caenorhabditis elegans. Curr Biol 12 (2002), 1738–1747.
    • (2002) Curr Biol , vol.12 , pp. 1738-1747
    • Kindt, K.S.1    Tam, T.2    Whiteman, S.3    Schafer, W.R.4
  • 106
    • 84890530721 scopus 로고    scopus 로고
    • Long-term outcomes of developmental exposure to fluoxetine: a review of the animal literature
    • Kiryanova, V., McAllister, B.B., Dyck, R.H., Long-term outcomes of developmental exposure to fluoxetine: a review of the animal literature. Dev Neurosci 35 (2013), 437–439.
    • (2013) Dev Neurosci , vol.35 , pp. 437-439
    • Kiryanova, V.1    McAllister, B.B.2    Dyck, R.H.3
  • 108
    • 79960968560 scopus 로고    scopus 로고
    • SLC6A4 methylation modifies the effect of the number of traumatic events on risk for posttraumatic stress disorder
    • Koenen, K.C., Uddin, M., Chang, S.C., Aiello, A.E., Wildman, D.E., Goldmann, E., Galea, S., SLC6A4 methylation modifies the effect of the number of traumatic events on risk for posttraumatic stress disorder. Depress Anxiety 28 (2011), 639–647.
    • (2011) Depress Anxiety , vol.28 , pp. 639-647
    • Koenen, K.C.1    Uddin, M.2    Chang, S.C.3    Aiello, A.E.4    Wildman, D.E.5    Goldmann, E.6    Galea, S.7
  • 109
    • 0038354618 scopus 로고    scopus 로고
    • Effects of exposure to selective serotonin reuptake inhibitors during pregnancy on serotonergic symptoms in newborns and cord blood monoamine and prolactin concentrations
    • Laine, K., Heikkinen, T., Ekblad, U., Kero, P., Effects of exposure to selective serotonin reuptake inhibitors during pregnancy on serotonergic symptoms in newborns and cord blood monoamine and prolactin concentrations. Arch Gen Psychiatry 60 (2003), 720–726.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 720-726
    • Laine, K.1    Heikkinen, T.2    Ekblad, U.3    Kero, P.4
  • 110
    • 0025646824 scopus 로고
    • Ontogeny of the serotonergic system in the rat: serotonin as a developmental signal
    • Lauder, J.M., Ontogeny of the serotonergic system in the rat: serotonin as a developmental signal. Ann NY Acad Sci 600 (1990), 297–313.
    • (1990) Ann NY Acad Sci , vol.600 , pp. 297-313
    • Lauder, J.M.1
  • 111
    • 0017064234 scopus 로고
    • Effects of p-chlorophenylalanine on time of neuronal origin during embryogenesis in the rat
    • Lauder, J.M., Krebs, H., Effects of p-chlorophenylalanine on time of neuronal origin during embryogenesis in the rat. Brain Res 107 (1976), 638–644.
    • (1976) Brain Res , vol.107 , pp. 638-644
    • Lauder, J.M.1    Krebs, H.2
  • 112
    • 34548348172 scopus 로고    scopus 로고
    • Linking emotion to the social brain. The role of the serotonin transporter in human social behaviour
    • Lesch, K.P., Linking emotion to the social brain. The role of the serotonin transporter in human social behaviour. EMBO Rep 8 (2007), S24–S29.
    • (2007) EMBO Rep , vol.8 , pp. S24-S29
    • Lesch, K.P.1
  • 113
    • 79958139576 scopus 로고    scopus 로고
    • When the serotonin transporter gene meets adversity: the contribution of animal models to understanding epigenetic mechanisms in affective disorders and resilience
    • Lesch, K.P., When the serotonin transporter gene meets adversity: the contribution of animal models to understanding epigenetic mechanisms in affective disorders and resilience. Curr Top Behav Neurosci 7 (2011), 251–280.
    • (2011) Curr Top Behav Neurosci , vol.7 , pp. 251-280
    • Lesch, K.P.1
  • 114
    • 80755176332 scopus 로고    scopus 로고
    • Serotonin and the autisms: a red flag or a red herring?
    • Levitt, P., Serotonin and the autisms: a red flag or a red herring?. Arch Gen Psychiatry, 2011.
    • (2011) Arch Gen Psychiatry
    • Levitt, P.1
  • 115
    • 80054710891 scopus 로고    scopus 로고
    • Neonatal fluoxetine exposure affects the action potential properties and dendritic development in cortical subplate neurons of rats
    • Liao, C.C., Lee, L.J., Neonatal fluoxetine exposure affects the action potential properties and dendritic development in cortical subplate neurons of rats. Toxicol Lett 207 (2011), 314–321.
    • (2011) Toxicol Lett , vol.207 , pp. 314-321
    • Liao, C.C.1    Lee, L.J.2
  • 116
    • 34347255039 scopus 로고    scopus 로고
    • First-trimester use of selective serotonin-reuptake inhibitors and the risk of birth defects
    • Louik, C., Lin, A.E., Werler, M.M., Hernandez-Diaz, S., Mitchell, A.A., First-trimester use of selective serotonin-reuptake inhibitors and the risk of birth defects. N Engl J Med 356 (2007), 2675–2683.
    • (2007) N Engl J Med , vol.356 , pp. 2675-2683
    • Louik, C.1    Lin, A.E.2    Werler, M.M.3    Hernandez-Diaz, S.4    Mitchell, A.A.5
  • 117
    • 0036854562 scopus 로고    scopus 로고
    • Functional subsets of serotonergic neurones: implications for control of the hypothalamic-pituitary–adrenal axis
    • Lowry, C.A., Functional subsets of serotonergic neurones: implications for control of the hypothalamic-pituitary–adrenal axis. J Neuroendocrinol 14 (2002), 911–923.
    • (2002) J Neuroendocrinol , vol.14 , pp. 911-923
    • Lowry, C.A.1
  • 118
  • 119
    • 67349157695 scopus 로고    scopus 로고
    • Effects of stress throughout the lifespan on the brain, behaviour and cognition
    • Lupien, S.J., McEwen, B.S., Gunnar, M.R., Heim, C., Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci 10 (2009), 434–445.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 434-445
    • Lupien, S.J.1    McEwen, B.S.2    Gunnar, M.R.3    Heim, C.4
  • 121
    • 33644535782 scopus 로고    scopus 로고
    • Neonatal citalopram exposure produces lasting changes in behavior which are reversed by adult imipramine treatment
    • Maciag, D., Williams, L., Coppinger, D., Paul, I.A., Neonatal citalopram exposure produces lasting changes in behavior which are reversed by adult imipramine treatment. Eur J Pharmacol 532 (2006), 265–269.
    • (2006) Eur J Pharmacol , vol.532 , pp. 265-269
    • Maciag, D.1    Williams, L.2    Coppinger, D.3    Paul, I.A.4
  • 122
    • 84891625665 scopus 로고    scopus 로고
    • Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects
    • Mahar, I., Bambico, F.R., Mechawar, N., Nobrega, J.N., Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects. Neurosci Biobehav Rev 38 (2014), 173–192.
    • (2014) Neurosci Biobehav Rev , vol.38 , pp. 173-192
    • Mahar, I.1    Bambico, F.R.2    Mechawar, N.3    Nobrega, J.N.4
  • 123
    • 84920903484 scopus 로고    scopus 로고
    • Exposure to selective serotonin reuptake inhibitors during pregnancy and risk of autism spectrum disorder in children: a systematic review and meta-analysis of observational studies
    • Man, K.K., Tong, H.H., Wong, L.Y., Chan, E.W., Simonoff, E., Wong, I.C., Exposure to selective serotonin reuptake inhibitors during pregnancy and risk of autism spectrum disorder in children: a systematic review and meta-analysis of observational studies. Neurosci Biobehav Rev 49 (2015), 82–89.
    • (2015) Neurosci Biobehav Rev , vol.49 , pp. 82-89
    • Man, K.K.1    Tong, H.H.2    Wong, L.Y.3    Chan, E.W.4    Simonoff, E.5    Wong, I.C.6
  • 124
    • 17444413709 scopus 로고    scopus 로고
    • Glucocorticoids, depression, and mood disorders: structural remodeling in the brain
    • McEwen, B.S., Glucocorticoids, depression, and mood disorders: structural remodeling in the brain. Metabolism 54 (2005), 20–23.
    • (2005) Metabolism , vol.54 , pp. 20-23
    • McEwen, B.S.1
  • 126
    • 0037096348 scopus 로고    scopus 로고
    • Expression of p73 and Reelin in the developing human cortex
    • Meyer, G., Perez-Garcia, C.G., Abraham, H., Caput, D., Expression of p73 and Reelin in the developing human cortex. J Neurosci 22 (2002), 4973–4986.
    • (2002) J Neurosci , vol.22 , pp. 4973-4986
    • Meyer, G.1    Perez-Garcia, C.G.2    Abraham, H.3    Caput, D.4
  • 127
    • 84884672306 scopus 로고    scopus 로고
    • Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation
    • Migliarini, S., Pacini, G., Pelosi, B., Lunardi, G., Pasqualetti, M., Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation. Mol Psychiatry 18 (2013), 1106–1118.
    • (2013) Mol Psychiatry , vol.18 , pp. 1106-1118
    • Migliarini, S.1    Pacini, G.2    Pelosi, B.3    Lunardi, G.4    Pasqualetti, M.5
  • 129
    • 79955483996 scopus 로고    scopus 로고
    • Prenatal stress induces anxiety-like behavior together with the disruption of central serotonin neurons in mice
    • Miyagawa, K., Tsuji, M., Fujimori, K., Saito, Y., Takeda, H., Prenatal stress induces anxiety-like behavior together with the disruption of central serotonin neurons in mice. Neurosci Res 70 (2011), 111–117.
    • (2011) Neurosci Res , vol.70 , pp. 111-117
    • Miyagawa, K.1    Tsuji, M.2    Fujimori, K.3    Saito, Y.4    Takeda, H.5
  • 130
    • 18344396274 scopus 로고    scopus 로고
    • Strategy for investigating interactions between measured genes and measured environments
    • Moffitt, T.E., Caspi, A., Rutter, M., Strategy for investigating interactions between measured genes and measured environments. Arch Gen Psychiatry 62 (2005), 473–481.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 473-481
    • Moffitt, T.E.1    Caspi, A.2    Rutter, M.3
  • 131
    • 0033965325 scopus 로고    scopus 로고
    • Maternal stress responses and anxiety during pregnancy: effects on fetal heart rate
    • Monk, C., Fifer, W.P., Myers, M.M., Sloan, R.P., Trien, L., Hurtado, A., Maternal stress responses and anxiety during pregnancy: effects on fetal heart rate. Dev Psychobiol 36 (2000), 67–77.
    • (2000) Dev Psychobiol , vol.36 , pp. 67-77
    • Monk, C.1    Fifer, W.P.2    Myers, M.M.3    Sloan, R.P.4    Trien, L.5    Hurtado, A.6
  • 132
    • 85008322788 scopus 로고    scopus 로고
    • Effects of in utero antidepressant (sertraline) exposure on offspring outcome in an animal model of maternal stress and depression
    • Society for Neuroscience Meeting Poster 347.14 Washington, DC, USA
    • Mooney-Leber, S., Kott, J.M., Shoubah, F.A., Perrine, S.A., Brummelte, S., Effects of in utero antidepressant (sertraline) exposure on offspring outcome in an animal model of maternal stress and depression. 2014, Society for Neuroscience Meeting Poster 347.14, Washington, DC, USA.
    • (2014)
    • Mooney-Leber, S.1    Kott, J.M.2    Shoubah, F.A.3    Perrine, S.A.4    Brummelte, S.5
  • 134
    • 0035955931 scopus 로고    scopus 로고
    • Fetal behavioural state changes following maternal fluoxetine infusion in sheep
    • Morrison, J.L., Chien, C., Gruber, N., Rurak, D., Riggs, W., Fetal behavioural state changes following maternal fluoxetine infusion in sheep. Brain Res Dev Brain Res 131 (2001), 47–56.
    • (2001) Brain Res Dev Brain Res , vol.131 , pp. 47-56
    • Morrison, J.L.1    Chien, C.2    Gruber, N.3    Rurak, D.4    Riggs, W.5
  • 135
    • 18644382386 scopus 로고    scopus 로고
    • Neonatal signs after late in utero exposure to serotonin reuptake inhibitors: literature review and implications for clinical applications
    • Moses-Kolko, E.L., Bogen, D., Perel, J., Bregar, A., Uhl, K., Levin, B., Wisner, K.L., Neonatal signs after late in utero exposure to serotonin reuptake inhibitors: literature review and implications for clinical applications. JAMA 293 (2005), 2372–2383.
    • (2005) JAMA , vol.293 , pp. 2372-2383
    • Moses-Kolko, E.L.1    Bogen, D.2    Perel, J.3    Bregar, A.4    Uhl, K.5    Levin, B.6    Wisner, K.L.7
  • 136
    • 54049086269 scopus 로고    scopus 로고
    • Sex-specific programming of offspring emotionality after stress early in pregnancy
    • Mueller, B.R., Bale, T.L., Sex-specific programming of offspring emotionality after stress early in pregnancy. J Neurosci 28 (2008), 9055–9065.
    • (2008) J Neurosci , vol.28 , pp. 9055-9065
    • Mueller, B.R.1    Bale, T.L.2
  • 137
    • 73949085728 scopus 로고    scopus 로고
    • The role of the serotonin transporter polymorphism for the endocrine stress response in newborns
    • Mueller, A., Brocke, B., Fries, E., Lesch, K.P., Kirschbaum, C., The role of the serotonin transporter polymorphism for the endocrine stress response in newborns. Psychoneuroendocrinology 35 (2010), 289–296.
    • (2010) Psychoneuroendocrinology , vol.35 , pp. 289-296
    • Mueller, A.1    Brocke, B.2    Fries, E.3    Lesch, K.P.4    Kirschbaum, C.5
  • 138
    • 58149308050 scopus 로고    scopus 로고
    • Gene + environment interactions at the serotonin transporter locus
    • Munafo, M.R., Durrant, C., Lewis, G., Flint, J., Gene + environment interactions at the serotonin transporter locus. Biol Psychiatry 65 (2009), 211–219.
    • (2009) Biol Psychiatry , vol.65 , pp. 211-219
    • Munafo, M.R.1    Durrant, C.2    Lewis, G.3    Flint, J.4
  • 139
    • 53649090041 scopus 로고    scopus 로고
    • How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems
    • Murphy, D.L., Fox, M.A., Timpano, K.R., Moya, P., Ren-Patterson, R., Andrews, A.M., Holmes, A., Watts, S.W., Wendland, J.R., Lesch, K.-P., How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems. Neuropharmacology 55 (2008), 932–960.
    • (2008) Neuropharmacology , vol.55 , pp. 932-960
    • Murphy, D.L.1    Fox, M.A.2    Timpano, K.R.3    Moya, P.4    Ren-Patterson, R.5    Andrews, A.M.6    Holmes, A.7    Watts, S.W.8    Wendland, J.R.9    Lesch, K.-P.10
  • 140
    • 84864067046 scopus 로고    scopus 로고
    • Origins: how the nine months before birth shape the rest of our lives
    • Free Press New York
    • Murphy Paul, A., Origins: how the nine months before birth shape the rest of our lives. 2010, Free Press, New York.
    • (2010)
    • Murphy Paul, A.1
  • 141
    • 77749330369 scopus 로고    scopus 로고
    • Serotonin, genetic variability, behaviour, and psychiatric disorders–a review
    • Nordquist, N., Oreland, L., Serotonin, genetic variability, behaviour, and psychiatric disorders–a review. Ups J Med Sci 115 (2010), 2–10.
    • (2010) Ups J Med Sci , vol.115 , pp. 2-10
    • Nordquist, N.1    Oreland, L.2
  • 143
    • 84864064091 scopus 로고    scopus 로고
    • Fetal serotonin signaling: setting pathways for early childhood development and behavior
    • Oberlander, T.F., Fetal serotonin signaling: setting pathways for early childhood development and behavior. J Adolesc Health 51 (2012), S9–S16.
    • (2012) J Adolesc Health , vol.51 , pp. S9-S16
    • Oberlander, T.F.1
  • 145
    • 1842866929 scopus 로고    scopus 로고
    • Pharmacologic factors associated with transient neonatal symptoms following prenatal psychotropic medication exposure
    • Oberlander, T.F., Misri, S., Fitzgerald, C.E., Kostaras, X., Rurak, D., Riggs, W., Pharmacologic factors associated with transient neonatal symptoms following prenatal psychotropic medication exposure. J Clin Psychiatry 65 (2004), 230–237.
    • (2004) J Clin Psychiatry , vol.65 , pp. 230-237
    • Oberlander, T.F.1    Misri, S.2    Fitzgerald, C.E.3    Kostaras, X.4    Rurak, D.5    Riggs, W.6
  • 146
    • 17644392473 scopus 로고    scopus 로고
    • Pain reactivity in 2-month-old infants after prenatal and postnatal serotonin reuptake inhibitor medication exposure
    • Oberlander, T.F., Grunau, R.E., Fitzgerald, C., Papsdorf, M., Rurak, D., Riggs, W., Pain reactivity in 2-month-old infants after prenatal and postnatal serotonin reuptake inhibitor medication exposure. Pediatrics 115 (2005), 411–425.
    • (2005) Pediatrics , vol.115 , pp. 411-425
    • Oberlander, T.F.1    Grunau, R.E.2    Fitzgerald, C.3    Papsdorf, M.4    Rurak, D.5    Riggs, W.6
  • 147
    • 33746869251 scopus 로고    scopus 로고
    • Neonatal outcomes after prenatal exposure to selective serotonin reuptake inhibitor antidepressants and maternal depression using population-based linked health data
    • Oberlander, T.F., Warburton, W., Misri, S., Aghajanian, J., Hertzman, C., Neonatal outcomes after prenatal exposure to selective serotonin reuptake inhibitor antidepressants and maternal depression using population-based linked health data. Arch Gen Psychiatry 63 (2006), 898–906.
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 898-906
    • Oberlander, T.F.1    Warburton, W.2    Misri, S.3    Aghajanian, J.4    Hertzman, C.5
  • 148
    • 33845994017 scopus 로고    scopus 로고
    • Externalizing and attentional behaviors in children of depressed mothers treated with a selective serotonin reuptake inhibitor antidepressant during pregnancy
    • Oberlander, T.F., Reebye, P., Misri, S., Papsdorf, M., Kim, J., Grunau, R., Externalizing and attentional behaviors in children of depressed mothers treated with a selective serotonin reuptake inhibitor antidepressant during pregnancy. Arch Pediatr Adolesc Med 161 (2007), 22–29.
    • (2007) Arch Pediatr Adolesc Med , vol.161 , pp. 22-29
    • Oberlander, T.F.1    Reebye, P.2    Misri, S.3    Papsdorf, M.4    Kim, J.5    Grunau, R.6
  • 149
    • 37249031342 scopus 로고    scopus 로고
    • Infant serotonin transporter (SLC6A4) promoter genotype is associated with adverse neonatal outcomes after prenatal exposure to serotonin reuptake inhibitor medications
    • Oberlander, T.F., Bonaguro, R.J., Misri, S., Papsdorf, M., Ross, C.J., Simpson, E.M., Infant serotonin transporter (SLC6A4) promoter genotype is associated with adverse neonatal outcomes after prenatal exposure to serotonin reuptake inhibitor medications. Mol Psychiatry 13 (2008), 65–73.
    • (2008) Mol Psychiatry , vol.13 , pp. 65-73
    • Oberlander, T.F.1    Bonaguro, R.J.2    Misri, S.3    Papsdorf, M.4    Ross, C.J.5    Simpson, E.M.6
  • 150
    • 53249119013 scopus 로고    scopus 로고
    • Hypothalamic-pituitary–adrenal (HPA) axis function in 3-month old infants with prenatal selective serotonin reuptake inhibitor (SSRI) antidepressant exposure
    • Oberlander, T.F., Grunau, R., Mayes, L., Riggs, W., Rurak, D., Papsdorf, M., Misri, S., Weinberg, J., Hypothalamic-pituitary–adrenal (HPA) axis function in 3-month old infants with prenatal selective serotonin reuptake inhibitor (SSRI) antidepressant exposure. Early Hum Dev 84 (2008), 689–697.
    • (2008) Early Hum Dev , vol.84 , pp. 689-697
    • Oberlander, T.F.1    Grunau, R.2    Mayes, L.3    Riggs, W.4    Rurak, D.5    Papsdorf, M.6    Misri, S.7    Weinberg, J.8
  • 151
    • 47149100122 scopus 로고    scopus 로고
    • Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses
    • Oberlander, T.F., Weinberg, J., Papsdorf, M., Grunau, R., Misri, S., Devlin, A.M., Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics 3 (2008), 97–106.
    • (2008) Epigenetics , vol.3 , pp. 97-106
    • Oberlander, T.F.1    Weinberg, J.2    Papsdorf, M.3    Grunau, R.4    Misri, S.5    Devlin, A.M.6
  • 152
    • 77951964308 scopus 로고    scopus 로고
    • Prenatal effects of selective serotonin reuptake inhibitor antidepressants, serotonin transporter promoter genotype (SLC6A4), and maternal mood on child behavior at 3 years of age
    • Oberlander, T.F., Papsdorf, M., Brain, U.M., Misri, S., Ross, C., Grunau, R.E., Prenatal effects of selective serotonin reuptake inhibitor antidepressants, serotonin transporter promoter genotype (SLC6A4), and maternal mood on child behavior at 3 years of age. Arch Pediatr Adolesc Med 164 (2010), 444–451.
    • (2010) Arch Pediatr Adolesc Med , vol.164 , pp. 444-451
    • Oberlander, T.F.1    Papsdorf, M.2    Brain, U.M.3    Misri, S.4    Ross, C.5    Grunau, R.E.6
  • 153
    • 79960439151 scopus 로고    scopus 로고
    • The age-dependent effects of selective serotonin reuptake inhibitors in humans and rodents: a review
    • Olivier, J.D., Blom, T., Arentsen, T., Homberg, J.R., The age-dependent effects of selective serotonin reuptake inhibitors in humans and rodents: a review. Prog Neuropsychopharmacol Biol Psychiatry 35 (2011), 1400–1408.
    • (2011) Prog Neuropsychopharmacol Biol Psychiatry , vol.35 , pp. 1400-1408
    • Olivier, J.D.1    Blom, T.2    Arentsen, T.3    Homberg, J.R.4
  • 154
    • 75949118126 scopus 로고    scopus 로고
    • Prospects for epigenetic research within cohort studies of psychological disorder: a pilot investigation of a peripheral cell marker of epigenetic risk for depression
    • Olsson, C.A., Foley, D.L., Parkinson-Bates, M., Byrnes, G., McKenzie, M., Patton, G.C., Morley, R., Anney, R.J.L., Craig, J.M., Saffery, R., Prospects for epigenetic research within cohort studies of psychological disorder: a pilot investigation of a peripheral cell marker of epigenetic risk for depression. Biol Psychol 83 (2010), 159–165.
    • (2010) Biol Psychol , vol.83 , pp. 159-165
    • Olsson, C.A.1    Foley, D.L.2    Parkinson-Bates, M.3    Byrnes, G.4    McKenzie, M.5    Patton, G.C.6    Morley, R.7    Anney, R.J.L.8    Craig, J.M.9    Saffery, R.10
  • 155
    • 84881430062 scopus 로고    scopus 로고
    • Increased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins
    • Ouellet-Morin, I., Wong, C.C.Y., Danese, A., Pariante, C.M., Papadopoulos, A.S., Mill, J., Arseneault, L., Increased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins. Psychol Med 43 (2013), 1813–1823.
    • (2013) Psychol Med , vol.43 , pp. 1813-1823
    • Ouellet-Morin, I.1    Wong, C.C.Y.2    Danese, A.3    Pariante, C.M.4    Papadopoulos, A.S.5    Mill, J.6    Arseneault, L.7
  • 157
    • 84555196737 scopus 로고    scopus 로고
    • Antidepressants in pregnancy: a review of commonly prescribed medications
    • Patil, A.S., Kuller, J.A., Rhee, E.H., Antidepressants in pregnancy: a review of commonly prescribed medications. Obstet Gynecol Surv 66 (2011), 777–787.
    • (2011) Obstet Gynecol Surv , vol.66 , pp. 777-787
    • Patil, A.S.1    Kuller, J.A.2    Rhee, E.H.3
  • 158
    • 70349729992 scopus 로고    scopus 로고
    • Neonatal S100B protein levels after prenatal exposure to selective serotonin reuptake inhibitors
    • Pawluski, J.L., Galea, L.A.M., Brain, U., Papsdorf, M., Oberlander, T.F., Neonatal S100B protein levels after prenatal exposure to selective serotonin reuptake inhibitors. Pediatrics 124 (2009), e662–e670.
    • (2009) Pediatrics , vol.124 , pp. e662-e670
    • Pawluski, J.L.1    Galea, L.A.M.2    Brain, U.3    Papsdorf, M.4    Oberlander, T.F.5
  • 159
    • 84897513165 scopus 로고    scopus 로고
    • Fluoxetine dose and administration method differentially affect hippocampal plasticity in adult female rats
    • Pawluski, J.L., van, D.E., Abrams, Z., Houbart, V., Fillet, M., Steinbusch, H.W., Charlier, T.D., Fluoxetine dose and administration method differentially affect hippocampal plasticity in adult female rats. Neural Plast, 2014, 2014, 123026.
    • (2014) Neural Plast , vol.2014 , pp. 123026
    • Pawluski, J.L.1    van, D.E.2    Abrams, Z.3    Houbart, V.4    Fillet, M.5    Steinbusch, H.W.6    Charlier, T.D.7
  • 162
    • 46949090009 scopus 로고    scopus 로고
    • The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies
    • Philibert, R.A., Sandhu, H., Hollenbeck, N., Gunter, T., Adams, W., Madan, A., The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies. Am J Med Genet B Neuropsychiatr Genet 147B (2008), 543–549.
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147B , pp. 543-549
    • Philibert, R.A.1    Sandhu, H.2    Hollenbeck, N.3    Gunter, T.4    Adams, W.5    Madan, A.6
  • 165
    • 43649087841 scopus 로고    scopus 로고
    • Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior
    • Popa, D., Lena, C., Alexandre, C., Adrien, J., Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior. J Neurosci 28 (2008), 3546–3554.
    • (2008) J Neurosci , vol.28 , pp. 3546-3554
    • Popa, D.1    Lena, C.2    Alexandre, C.3    Adrien, J.4
  • 166
    • 84878304990 scopus 로고    scopus 로고
    • Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study
    • Rai, D., Lee, B.K., Dalman, C., Golding, J., Lewis, G., Magnusson, C., Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study. BMJ, 346, 2013, f2059.
    • (2013) BMJ , vol.346 , pp. f2059
    • Rai, D.1    Lee, B.K.2    Dalman, C.3    Golding, J.4    Lewis, G.5    Magnusson, C.6
  • 167
  • 170
    • 80052381901 scopus 로고    scopus 로고
    • Fluoxetine during development reverses the effects of prenatal stress on depressive-like behavior and hippocampal neurogenesis in adolescence
    • Rayen, I., Van Den Hove, D.L., Prickaerts, J., Steinbusch, H.W., Pawluski, J.L., Fluoxetine during development reverses the effects of prenatal stress on depressive-like behavior and hippocampal neurogenesis in adolescence. PLoS One, 6, 2011, e24003.
    • (2011) PLoS One , vol.6 , pp. e24003
    • Rayen, I.1    Van Den Hove, D.L.2    Prickaerts, J.3    Steinbusch, H.W.4    Pawluski, J.L.5
  • 171
    • 60549089578 scopus 로고    scopus 로고
    • Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6
    • Riccio, O., Potter, G., Walzer, C., Vallet, P., Szabo, G., Vutskits, L., Kiss, J.Z., Dayer, A.G., Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6. Mol Psychiatry 14 (2009), 280–290.
    • (2009) Mol Psychiatry , vol.14 , pp. 280-290
    • Riccio, O.1    Potter, G.2    Walzer, C.3    Vallet, P.4    Szabo, G.5    Vutskits, L.6    Kiss, J.Z.7    Dayer, A.G.8
  • 172
    • 67649206975 scopus 로고    scopus 로고
    • Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis
    • Risch, N., Herrell, R., Lehner, T., Liang, K.Y., Eaves, L., Hoh, J., Griem, A., Kovacs, M., Ott, J., Merikangas, K.R., Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. JAMA 301 (2009), 2462–2471.
    • (2009) JAMA , vol.301 , pp. 2462-2471
    • Risch, N.1    Herrell, R.2    Lehner, T.3    Liang, K.Y.4    Eaves, L.5    Hoh, J.6    Griem, A.7    Kovacs, M.8    Ott, J.9    Merikangas, K.R.10
  • 174
    • 79952648592 scopus 로고    scopus 로고
    • Annual Research Review: epigenetic mechanisms and environmental shaping of the brain during sensitive periods of development
    • Roth, T.L., Sweatt, J.D., Annual Research Review: epigenetic mechanisms and environmental shaping of the brain during sensitive periods of development. J Child Psychol Psychiatry 52 (2011), 398–408.
    • (2011) J Child Psychol Psychiatry , vol.52 , pp. 398-408
    • Roth, T.L.1    Sweatt, J.D.2
  • 175
    • 79960274560 scopus 로고    scopus 로고
    • Third trimester fetal heart rate and Doppler middle cerebral artery blood flow velocity characteristics during prenatal selective serotonin reuptake inhibitor exposure
    • Rurak, D., Lim, K., Sanders, A., Brain, U., Riggs, W., Riggs, W., Oberlander, T.F., Third trimester fetal heart rate and Doppler middle cerebral artery blood flow velocity characteristics during prenatal selective serotonin reuptake inhibitor exposure. Pediatr Res 70 (2011), 96–101.
    • (2011) Pediatr Res , vol.70 , pp. 96-101
    • Rurak, D.1    Lim, K.2    Sanders, A.3    Brain, U.4    Riggs, W.5    Riggs, W.6    Oberlander, T.F.7
  • 176
    • 0035112990 scopus 로고    scopus 로고
    • Excessive activation of serotonin (5-HT) 1B receptors disrupts the formation of sensory maps in monoamine oxidase a and 5-ht transporter knock-out mice
    • Salichon, N., Gaspar, P., Upton, A.L., Picaud, S., Hanoun, N., Hamon, M., De Maeyer, E., Murphy, D.L., Mossner, R., Lesch, K.P., Hen, R., Seif, I., Excessive activation of serotonin (5-HT) 1B receptors disrupts the formation of sensory maps in monoamine oxidase a and 5-ht transporter knock-out mice. J Neurosci 21:3 (2001), 884–896.
    • (2001) J Neurosci , vol.21 , Issue.3 , pp. 884-896
    • Salichon, N.1    Gaspar, P.2    Upton, A.L.3    Picaud, S.4    Hanoun, N.5    Hamon, M.6    De Maeyer, E.7    Murphy, D.L.8    Mossner, R.9    Lesch, K.P.10    Hen, R.11    Seif, I.12
  • 178
    • 54849404294 scopus 로고    scopus 로고
    • Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants
    • Savelieva, K.V., Zhao, S., Pogorelov, V.M., Rajan, I., Yang, Q., Cullinan, E., Lanthorn, T.H., Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants. PLoS One, 3, 2008, e3301.
    • (2008) PLoS One , vol.3 , pp. e3301
    • Savelieva, K.V.1    Zhao, S.2    Pogorelov, V.M.3    Rajan, I.4    Yang, Q.5    Cullinan, E.6    Lanthorn, T.H.7
  • 179
    • 1542314848 scopus 로고    scopus 로고
    • A meta-analysis of the association between the serotonin transporter gene polymorphism (5-HTTLPR) and trait anxiety
    • Schinka, J.A., Busch, R.M., Robichaux-Keene, N., A meta-analysis of the association between the serotonin transporter gene polymorphism (5-HTTLPR) and trait anxiety. Mol Psychiatry 9 (2004), 197–202.
    • (2004) Mol Psychiatry , vol.9 , pp. 197-202
    • Schinka, J.A.1    Busch, R.M.2    Robichaux-Keene, N.3
  • 180
    • 14544269336 scopus 로고    scopus 로고
    • Glucocorticoid programming
    • Seckl, J.R., Meaney, M.J., Glucocorticoid programming. Ann NY Acad Sci 1032 (2004), 63–84.
    • (2004) Ann NY Acad Sci , vol.1032 , pp. 63-84
    • Seckl, J.R.1    Meaney, M.J.2
  • 182
    • 2142817209 scopus 로고    scopus 로고
    • Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traits
    • Sen, S., Burmeister, M., Ghosh, D., Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traits. Am J Med Genet B Neuropsychiatr Genet 127B (2004), 85–89.
    • (2004) Am J Med Genet B Neuropsychiatr Genet , vol.127B , pp. 85-89
    • Sen, S.1    Burmeister, M.2    Ghosh, D.3
  • 183
    • 33845309080 scopus 로고    scopus 로고
    • Serotonin transporter gene variants and behavior: a comprehensive review
    • Serretti, A., Calati, R., Mandelli, L., De, R.D., Serotonin transporter gene variants and behavior: a comprehensive review. Curr Drug Targets 7 (2006), 1659–1669.
    • (2006) Curr Drug Targets , vol.7 , pp. 1659-1669
    • Serretti, A.1    Calati, R.2    Mandelli, L.3    De, R.D.4
  • 184
    • 0032433926 scopus 로고    scopus 로고
    • Relationship between [125I]RTI-55-labeled cocaine binding sites and the serotonin transporter in rat placenta
    • Shearman, L.P., McReynolds, A.M., Zhou, F.C., Meyer, J.S., Relationship between [125I]RTI-55-labeled cocaine binding sites and the serotonin transporter in rat placenta. Am J Physiol 275 (1998), C1621–C1629.
    • (1998) Am J Physiol , vol.275 , pp. C1621-C1629
    • Shearman, L.P.1    McReynolds, A.M.2    Zhou, F.C.3    Meyer, J.S.4
  • 186
  • 189
    • 34447324675 scopus 로고    scopus 로고
    • Maternal care, the epigenome and phenotypic differences in behavior
    • Szyf, M., Weaver, I., Meaney, M., Maternal care, the epigenome and phenotypic differences in behavior. Reprod Toxicol 24 (2007), 9–19.
    • (2007) Reprod Toxicol , vol.24 , pp. 9-19
    • Szyf, M.1    Weaver, I.2    Meaney, M.3
  • 190
    • 0022514780 scopus 로고
    • Distribution of serotonin-containing cell bodies in the brainstem of the human fetus determined with immunohistochemistry using antiserotonin serum
    • Takahashi, H., Nakashima, S., Ohama, E., Takeda, S., Ikuta, F., Distribution of serotonin-containing cell bodies in the brainstem of the human fetus determined with immunohistochemistry using antiserotonin serum. Brain Dev 8:4 (1986), 355–365.
    • (1986) Brain Dev , vol.8 , Issue.4 , pp. 355-365
    • Takahashi, H.1    Nakashima, S.2    Ohama, E.3    Takeda, S.4    Ikuta, F.5
  • 191
    • 33847765900 scopus 로고    scopus 로고
    • Antenatal maternal stress and long-term effects on child neurodevelopment: how and why?
    • Talge, N.M., Neal, C., Glover, V., Antenatal maternal stress and long-term effects on child neurodevelopment: how and why?. J Child Psychol Psychiatry 48 (2007), 245–261.
    • (2007) J Child Psychol Psychiatry , vol.48 , pp. 245-261
    • Talge, N.M.1    Neal, C.2    Glover, V.3
  • 192
    • 33748895036 scopus 로고    scopus 로고
    • Early family environment, current adversity, the serotonin transporter promoter polymorphism, and depressive symptomatology
    • Taylor, S.E., Way, B.M., Welch, W.T., Hilmert, C.J., Lehman, B.J., Eisenberger, N.I., Early family environment, current adversity, the serotonin transporter promoter polymorphism, and depressive symptomatology. Biol Psychiatry 60 (2006), 671–676.
    • (2006) Biol Psychiatry , vol.60 , pp. 671-676
    • Taylor, S.E.1    Way, B.M.2    Welch, W.T.3    Hilmert, C.J.4    Lehman, B.J.5    Eisenberger, N.I.6
  • 193
    • 0037704311 scopus 로고    scopus 로고
    • Reelin and brain development
    • Tissir, F., Goffinet, A.M., Reelin and brain development. Nat Rev Neurosci 4 (2003), 496–505.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 496-505
    • Tissir, F.1    Goffinet, A.M.2
  • 195
    • 0002317218 scopus 로고    scopus 로고
    • Depressed mothers and infants: failure to form dyadic states of consciousness
    • L. Murray P.J. Cooper Guilford Press New York
    • Tronick, E.Z., Weinberg, M.K., Depressed mothers and infants: failure to form dyadic states of consciousness. Murray, L., Cooper, P.J., (eds.) Postpartum depression and child development, 1997, Guilford Press, New York, 54–81.
    • (1997) Postpartum depression and child development , pp. 54-81
    • Tronick, E.Z.1    Weinberg, M.K.2
  • 196
    • 84951569507 scopus 로고    scopus 로고
    • Effects of the social environment and stress on glucocorticoid receptor gene methylation: a systematic review
    • Turecki, G., Meaney, M.J., Effects of the social environment and stress on glucocorticoid receptor gene methylation: a systematic review. Biol Psychiatry 79:2 (2016), 87–96.
    • (2016) Biol Psychiatry , vol.79 , Issue.2 , pp. 87-96
    • Turecki, G.1    Meaney, M.J.2
  • 197
    • 38149076376 scopus 로고    scopus 로고
    • Antenatal maternal anxiety is related to HPA-axis dysregulation and self-reported depressive symptoms in adolescence: a prospective study on the fetal origins of depressed mood
    • Van den Bergh, B.R., Van, C.B., Smits, T., Van, H.S., Lagae, L., Antenatal maternal anxiety is related to HPA-axis dysregulation and self-reported depressive symptoms in adolescence: a prospective study on the fetal origins of depressed mood. Neuropsychopharmacology 33 (2008), 536–545.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 536-545
    • Van den Bergh, B.R.1    Van, C.B.2    Smits, T.3    Van, H.S.4    Lagae, L.5
  • 199
    • 77955611775 scopus 로고    scopus 로고
    • Methylation matters: interaction between methylation density and serotonin transporter genotype predicts unresolved loss or trauma
    • van, I.J., Zendoorn, M.H., Caspers, K., Bakermans-Kranenburg, M.J., Beach, S.R., Philibert, R., Methylation matters: interaction between methylation density and serotonin transporter genotype predicts unresolved loss or trauma. Biol Psychiatry 68 (2010), 405–407.
    • (2010) Biol Psychiatry , vol.68 , pp. 405-407
    • van, I.J.1    Zendoorn, M.H.2    Caspers, K.3    Bakermans-Kranenburg, M.J.4    Beach, S.R.5    Philibert, R.6
  • 200
    • 84862102077 scopus 로고    scopus 로고
    • Insights into the complex influence of 5-HT signaling on thalamocortical axonal system development
    • van Kleef, E.S., Gaspar, P., Bonnin, A., Insights into the complex influence of 5-HT signaling on thalamocortical axonal system development. Eur J Neurosci 35 (2012), 1563–1572.
    • (2012) Eur J Neurosci , vol.35 , pp. 1563-1572
    • van Kleef, E.S.1    Gaspar, P.2    Bonnin, A.3
  • 201
    • 0035211187 scopus 로고    scopus 로고
    • The extraneuronal monoamine transporter Slc22a3/Orct3 co-localizes with the Maoa metabolizing enzyme in mouse placenta
    • Verhaagh, S., Barlow, D.P., Zwart, R., The extraneuronal monoamine transporter Slc22a3/Orct3 co-localizes with the Maoa metabolizing enzyme in mouse placenta. Mech Dev 100 (2001), 127–130.
    • (2001) Mech Dev , vol.100 , pp. 127-130
    • Verhaagh, S.1    Barlow, D.P.2    Zwart, R.3
  • 203
    • 84862667231 scopus 로고    scopus 로고
    • Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression
    • Wang, D., Szyf, M., Benkelfat, C., Provencal, N., Turecki, G., Caramaschi, D., Cote, S.M., Vitaro, F., Tremblay, R.E., Booij, L., Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression. PLoS One, 7, 2012, e39501.
    • (2012) PLoS One , vol.7 , pp. e39501
    • Wang, D.1    Szyf, M.2    Benkelfat, C.3    Provencal, N.4    Turecki, G.5    Caramaschi, D.6    Cote, S.M.7    Vitaro, F.8    Tremblay, R.E.9    Booij, L.10
  • 204
    • 77951923879 scopus 로고    scopus 로고
    • A register study of the impact of stopping third trimester selective serotonin reuptake inhibitor exposure on neonatal health
    • Warburton, W., Hertzman, C., Oberlander, T.F., A register study of the impact of stopping third trimester selective serotonin reuptake inhibitor exposure on neonatal health. Acta Psychiatr Scand 121 (2010), 471–479.
    • (2010) Acta Psychiatr Scand , vol.121 , pp. 471-479
    • Warburton, W.1    Hertzman, C.2    Oberlander, T.F.3
  • 205
    • 77649113086 scopus 로고    scopus 로고
    • Social influences on health: is serotonin a critical mediator?
    • Way, B.M., Taylor, S.E., Social influences on health: is serotonin a critical mediator?. Psychosom Med 72 (2010), 107–112.
    • (2010) Psychosom Med , vol.72 , pp. 107-112
    • Way, B.M.1    Taylor, S.E.2
  • 207
    • 84864979200 scopus 로고    scopus 로고
    • Prenatal exposure to antidepressants and depressed maternal mood alter trajectory of infant speech perception
    • Weikum, W.M., Oberlander, T.F., Hensch, T.K., Werker, J.F., Prenatal exposure to antidepressants and depressed maternal mood alter trajectory of infant speech perception. Proc Natl Acad Sci U S A 109 (2012), 17221–17227.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 17221-17227
    • Weikum, W.M.1    Oberlander, T.F.2    Hensch, T.K.3    Werker, J.F.4
  • 208
    • 84886813311 scopus 로고    scopus 로고
    • Prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and serotonin transporter promoter genotype (SLC6A4) influence executive functions at 6 years of age
    • Weikum, W., Brain, U., Chau, C.M., Grunau, R.E., Boyce, W.T., Diamond, A., Oberlander, T.F., Prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and serotonin transporter promoter genotype (SLC6A4) influence executive functions at 6 years of age. Front Cell Neurosci, 7, 2013.
    • (2013) Front Cell Neurosci , vol.7
    • Weikum, W.1    Brain, U.2    Chau, C.M.3    Grunau, R.E.4    Boyce, W.T.5    Diamond, A.6    Oberlander, T.F.7
  • 209
    • 0035180462 scopus 로고    scopus 로고
    • Prenatal stress, glucocorticoids and the programming of the brain
    • Welberg, L.A., Seckl, J.R., Prenatal stress, glucocorticoids and the programming of the brain. J Neuroendocrinol 13 (2001), 113–128.
    • (2001) J Neuroendocrinol , vol.13 , pp. 113-128
    • Welberg, L.A.1    Seckl, J.R.2
  • 210
    • 0035891882 scopus 로고    scopus 로고
    • Serotonin and brain development: role in human developmental diseases
    • Whitaker-Azmitia, P.M., Serotonin and brain development: role in human developmental diseases. Brain Res Bull 56 (2001), 479–485.
    • (2001) Brain Res Bull , vol.56 , pp. 479-485
    • Whitaker-Azmitia, P.M.1
  • 211
    • 13844311589 scopus 로고    scopus 로고
    • Behavioral and cellular consequences of increasing serotonergic activity during brain development: a role in autism?
    • Whitaker-Azmitia, P.M., Behavioral and cellular consequences of increasing serotonergic activity during brain development: a role in autism?. Int J Dev Neurosci 23:1 (2005), 75–83.
    • (2005) Int J Dev Neurosci , vol.23 , Issue.1 , pp. 75-83
    • Whitaker-Azmitia, P.M.1
  • 213
    • 33749022748 scopus 로고    scopus 로고
    • How lifetimes shape epigenotype within and across generations
    • 15 Spec No 2
    • Whitelaw, N.C., Whitelaw, E., How lifetimes shape epigenotype within and across generations. Hum Mol Genet, 2006, R131–R137 15 Spec No 2.
    • (2006) Hum Mol Genet , pp. R131-R137
    • Whitelaw, N.C.1    Whitelaw, E.2
  • 214
    • 25844486031 scopus 로고    scopus 로고
    • The serotonin transporter length polymorphism, neuroticism, and depression: a comprehensive assessment of association
    • Willis-Owen, S.A., Turri, M.G., Munafo, M.R., Surtees, P.G., Wainwright, N.W., Brixey, R.D., Flint, J., The serotonin transporter length polymorphism, neuroticism, and depression: a comprehensive assessment of association. Biol Psychiatry 58 (2005), 451–456.
    • (2005) Biol Psychiatry , vol.58 , pp. 451-456
    • Willis-Owen, S.A.1    Turri, M.G.2    Munafo, M.R.3    Surtees, P.G.4    Wainwright, N.W.5    Brixey, R.D.6    Flint, J.7
  • 215
    • 70449723281 scopus 로고    scopus 로고
    • SSRIs and congenital defects. Case registers in pregnancy?
    • Yadav, D.S., SSRIs and congenital defects. Case registers in pregnancy?. BMJ, 339, 2009, b4286.
    • (2009) BMJ , vol.339 , pp. b4286
    • Yadav, D.S.1
  • 216
    • 84939816593 scopus 로고    scopus 로고
    • Sex- and SERT-associated differences in stimulated serotonin revealed by fast microdialysis
    • Yang, H., Sampson, M.M., Senturk, D., Andrews, A.M., Sex- and SERT-associated differences in stimulated serotonin revealed by fast microdialysis. ACS Chem Neurosci 6 (2015), 1487–1501.
    • (2015) ACS Chem Neurosci , vol.6 , pp. 1487-1501
    • Yang, H.1    Sampson, M.M.2    Senturk, D.3    Andrews, A.M.4
  • 217
    • 0027295245 scopus 로고
    • Serotonin uptake in the ectoplacental cone and placenta of the mouse
    • Yavarone, M.S., Shuey, D.L., Sadler, T.W., Lauder, J.M., Serotonin uptake in the ectoplacental cone and placenta of the mouse. Placenta 14 (1993), 149–161.
    • (1993) Placenta , vol.14 , pp. 149-161
    • Yavarone, M.S.1    Shuey, D.L.2    Sadler, T.W.3    Lauder, J.M.4
  • 218
    • 0842346538 scopus 로고    scopus 로고
    • Maternal selective serotonin reuptake inhibitor use during pregnancy and newborn neurobehavior
    • Zeskind, P.S., Stephens, L.E., Maternal selective serotonin reuptake inhibitor use during pregnancy and newborn neurobehavior. Pediatrics 113 (2004), 368–375.
    • (2004) Pediatrics , vol.113 , pp. 368-375
    • Zeskind, P.S.1    Stephens, L.E.2
  • 219
    • 79958716541 scopus 로고    scopus 로고
    • Neonatal exposure to fluoxetine and fluvoxamine alteres spine density in mouse hippocampal CA1 pyramidal neurons
    • Zheng, J., Xu, D.F., Li, K., Wang, H.T., Shen, P.C., Lin, M., Cao, X.H., Wang, R., Neonatal exposure to fluoxetine and fluvoxamine alteres spine density in mouse hippocampal CA1 pyramidal neurons. Int J Clin Exp Pathol 4 (2011), 162–168.
    • (2011) Int J Clin Exp Pathol , vol.4 , pp. 162-168
    • Zheng, J.1    Xu, D.F.2    Li, K.3    Wang, H.T.4    Shen, P.C.5    Lin, M.6    Cao, X.H.7    Wang, R.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.