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Volumn 18, Issue 10, 2013, Pages 1106-1118

Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation

Author keywords

BDNF; neural development; neurodevelopmental disorders; serotonergic innervation; serotonin; Tph2

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; ENHANCED GREEN FLUORESCENT PROTEIN; SEROTONIN;

EID: 84884672306     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2012.128     Document Type: Article
Times cited : (175)

References (55)
  • 1
    • 3042719619 scopus 로고    scopus 로고
    • The developmental origins of anxiety
    • Gross C, Hen R. The developmental origins of anxiety. Nat Rev Neurosci 2004; 5: 545-552. (Pubitemid 38868550)
    • (2004) Nature Reviews Neuroscience , vol.5 , Issue.7 , pp. 545-552
    • Gross, C.1    Hen, R.2
  • 2
    • 0032145210 scopus 로고    scopus 로고
    • The spectrum of behaviors influenced by serotonin
    • DOI 10.1016/S0006-3223(98)00139-5, PII S0006322398001395
    • Lucki I. The spectrum of behaviors influenced by serotonin. Biol Psychiatry 1998; 44: 151-162. (Pubitemid 28378297)
    • (1998) Biological Psychiatry , vol.44 , Issue.3 , pp. 151-162
    • Lucki, I.1
  • 4
    • 0034723057 scopus 로고    scopus 로고
    • Pharmacogenetics and the serotonin system: Initial studies and future directions
    • DOI 10.1016/S0014-2999(00)00814-1, PII S0014299900008141
    • Veenstra-VanderWeele J, Anderson GM, Cook Jr EH. Pharmacogenetics and the serotonin system: initial studies and future directions. Eur J Pharmacol 2000; 410: 165-181. (Pubitemid 32008142)
    • (2000) European Journal of Pharmacology , vol.410 , Issue.2-3 , pp. 165-181
    • Veenstra-VanderWeele, J.1    Anderson, G.M.2    Cook Jr., E.H.3
  • 5
    • 0020467289 scopus 로고
    • Immunohistochemical study of the development of serotonergic neurons in the rat CNS
    • DOI 10.1016/0361-9230(82)90164-2
    • Lidov HG, Molliver ME. Immunohistochemical study of the development of serotonergic neurons in the rat CNS. Brain Res Bull 1982; 9: 559-604. (Pubitemid 13166425)
    • (1982) Brain Research Bulletin , vol.9 , Issue.1-6 , pp. 559-604
    • Lidov, H.G.W.1    Molliver, M.E.2
  • 6
    • 0020636924 scopus 로고
    • Development of the serotonergic system in the rat embryo: An immunocytochemical study
    • DOI 10.1016/0361-9230(83)90144-2
    • Wallace JA, Lauder JM. Development of the serotonergic system in the rat embryo: an immunocytochemical study. Brain Res Bull 1983; 10: 459-479. (Pubitemid 13098792)
    • (1983) Brain Research Bulletin , vol.10 , Issue.4 , pp. 459-479
    • Wallace, J.A.1    Lauder, J.M.2
  • 7
    • 79955447412 scopus 로고    scopus 로고
    • A transient placental source of serotonin for the fetal forebrain
    • Bonnin A, Goeden N, Chen K, Wilson ML, King J, Shih JC et al. A transient placental source of serotonin for the fetal forebrain. Nature 2011; 472: 347-350.
    • (2011) Nature , vol.472 , pp. 347-350
    • Bonnin, A.1    Goeden, N.2    Chen, K.3    Wilson, M.L.4    King, J.5    Shih, J.C.6
  • 9
    • 0345258497 scopus 로고    scopus 로고
    • The developmental role of serotonin: News from mouse molecular genetics
    • Gaspar P, Cases O, Maroteaux L. The developmental role of serotonin: news from mouse molecular genetics. Nat Rev Neurosci 2003; 4: 1002-1012. (Pubitemid 37486676)
    • (2003) Nature Reviews Neuroscience , vol.4 , Issue.12 , pp. 1002-1012
    • Gaspar, P.1    Cases, O.2    Maroteaux, L.3
  • 10
    • 0027300281 scopus 로고
    • Neurotransmitters as growth regulatory signals: Role of receptors and second messengers
    • DOI 10.1016/0166-2236(93)90162-F
    • Lauder JM. Neurotransmitters as growth regulatory signals: role of receptors and second messengers. Trends Neurosci 1993; 16: 233-240. (Pubitemid 23139188)
    • (1993) Trends in Neurosciences , vol.16 , Issue.6 , pp. 233-240
    • Lauder, J.M.1
  • 11
    • 0032987647 scopus 로고    scopus 로고
    • Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children
    • DOI 10.1002/1531-8249(199903)45:3<287::AID-ANA3>3.0.CO;2-9
    • Chugani DC, Muzik O, Behen M, Rothermel R, Janisse JJ, Lee J et al. Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children. Ann Neurol 1999; 45: 287-295. (Pubitemid 29120032)
    • (1999) Annals of Neurology , vol.45 , Issue.3 , pp. 287-295
    • Chugani, D.C.1    Muzik, O.2    Behen, M.3    Rothermel, R.4    Janisse, J.J.5    Lee, J.6    Chugani, H.T.7
  • 13
    • 0035891882 scopus 로고    scopus 로고
    • Serotonin and brain development: Role in human developmental diseases
    • DOI 10.1016/S0361-9230(01)00615-3, PII S0361923001006153
    • Whitaker-Azmitia PM. Serotonin and brain development: role in human developmental diseases. Brain Res Bull 2001; 56: 479-485. (Pubitemid 34031783)
    • (2001) Brain Research Bulletin , vol.56 , Issue.5 , pp. 479-485
    • Whitaker-Azmitia, P.M.1
  • 14
    • 0030058732 scopus 로고    scopus 로고
    • Lack of barrels in the somatosensory cortex of monoamine oxidase A-deficient mice: Role of a serotonin excess during the critical period
    • Cases O, Vitalis T, Seif I, De Maeyer E, Sotelo C, Gaspar P. Lack of barrels in the somatosensory cortex of monoamine oxidase A-deficient mice: role of a serotonin excess during the critical period. Neuron 1996; 16: 297-307.
    • (1996) Neuron , vol.16 , pp. 297-307
    • Cases, O.1    Vitalis, T.2    Seif, I.3    De Maeyer, E.4    Sotelo, C.5    Gaspar, P.6
  • 16
    • 60549089578 scopus 로고    scopus 로고
    • Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6
    • Riccio O, Potter G, Walzer C, Vallet P, Szabo G, Vutskits L et al. Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6. Mol Psychiatry 2009; 14: 280-290.
    • (2009) Mol Psychiatry , vol.14 , pp. 280-290
    • Riccio, O.1    Potter, G.2    Walzer, C.3    Vallet, P.4    Szabo, G.5    Vutskits, L.6
  • 19
  • 20
    • 49749117799 scopus 로고    scopus 로고
    • Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice
    • Gutknecht L, Waider J, Kraft S, Kriegebaum C, Holtmann B, Reif A et al. Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice. J Neural Transm 2008; 115: 1127-1132.
    • (2008) J Neural Transm , vol.115 , pp. 1127-1132
    • Gutknecht, L.1    Waider, J.2    Kraft, S.3    Kriegebaum, C.4    Holtmann, B.5    Reif, A.6
  • 21
    • 84884674126 scopus 로고    scopus 로고
    • Generation of a Tph2/EGFP knockin mouse line for the study of the role of serotonin during the central nervous system development
    • (abstract SCP055)
    • Migliarini S, Pacini G, Pasqualetti M. Generation of a Tph2/EGFP knockin mouse line for the study of the role of serotonin during the central nervous system development. Fundam Clin Pharmacol 2008; 22(Suppl.2): 129 (abstract SCP055).
    • (2008) Fundam Clin Pharmacol , vol.22 , Issue.SUPPL.2 , pp. 129
    • Migliarini, S.1    Pacini, G.2    Pasqualetti, M.3
  • 22
    • 54849404294 scopus 로고    scopus 로고
    • Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants
    • Savelieva KV, Zhao S, Pogorelov VM, Rajan I, Yang Q, Cullinan E et al. Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants. PLoS One 2008; 3: e3301.
    • (2008) PLoS One , vol.3
    • Savelieva, K.V.1    Zhao, S.2    Pogorelov, V.M.3    Rajan, I.4    Yang, Q.5    Cullinan, E.6
  • 23
    • 69449083603 scopus 로고    scopus 로고
    • A serotonindependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure
    • Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C et al. A serotonindependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell 2009; 138: 976-989.
    • (2009) Cell , vol.138 , pp. 976-989
    • Yadav, V.K.1    Oury, F.2    Suda, N.3    Liu, Z.W.4    Gao, X.B.5    Confavreux, C.6
  • 24
    • 84884674050 scopus 로고    scopus 로고
    • Tryptophan hydroxylase 2 (Tph2) knockout mice reveal a critical role for brain serotonin (5-HT) in postnatal development and in adult behaviour
    • Chicago (abstract 61.3/N36)
    • Migliarini S, Pacini G, Pelosi B, Errico F, Lunardi G, Usiello A et al. Tryptophan hydroxylase 2 (Tph2) knockout mice reveal a critical role for brain serotonin (5-HT) in postnatal development and in adult behaviour. Society for Neuroscience, Chicago 2009, (abstract 61.3/N36).
    • (2009) Society for Neuroscience
    • Migliarini, S.1    Pacini, G.2    Pelosi, B.3    Errico, F.4    Lunardi, G.5    Usiello, A.6
  • 25
    • 0025666925 scopus 로고
    • Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity
    • Nichols J, Evans EP, Smith AG. Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity. Development 1990; 110: 1341-1348. (Pubitemid 120009502)
    • (1990) Development , vol.110 , Issue.4 , pp. 1341-1348
    • Nichols, J.1    Evans, E.P.2    Smith, A.G.3
  • 26
    • 0035308590 scopus 로고    scopus 로고
    • A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA
    • DOI 10.1006/geno.2000.6451
    • Lee EC, Yu D, Martinez de Velasco J, Tessarollo L, Swing DA, Court DL et al. A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics 2001; 73: 56-65. (Pubitemid 32382387)
    • (2001) Genomics , vol.73 , Issue.1 , pp. 56-65
    • Lee, E.-C.1    Yu, D.2    Martinez De Velasco, J.3    Tessarollo, L.4    Swing, D.A.5    Court, D.L.6    Jenkins, N.A.7    Copeland, N.G.8
  • 27
    • 0036195992 scopus 로고    scopus 로고
    • A Hoxa2 mutant conditional allele generated by Flp- and Cre-mediated recombination
    • DOI 10.1002/gene.10052
    • Ren SY, Pasqualetti M, Dierich A, Le Meur M, Rijli FM. A Hoxa2 mutant conditional allele generated by Flp-and Cre-mediated recombination. Genesis 2002; 32: 105-108. (Pubitemid 34211710)
    • (2002) Genesis , vol.32 , Issue.2 , pp. 105-108
    • Ren, S.-Y.1    Pasqualetti, M.2    Dierich, A.3    Le Meur, M.4    Rijli, F.M.5
  • 29
    • 0023856405 scopus 로고
    • Quantitative evaluation of vascular permeability in the gerbil brain after transient ischemia using Evans blue fluorescence
    • Uyama O, Okamura N, Yanase M, Narita M, Kawabata K, Sugita M. Quantitative evaluation of vascular permeability in the gerbil brain after transient ischemia using Evans blue fluorescence. J Cereb Blood Flow Metab 1988; 8: 282-284. (Pubitemid 18079698)
    • (1988) Journal of Cerebral Blood Flow and Metabolism , vol.8 , Issue.2 , pp. 282-284
    • Uyama, O.1    Okamura, N.2    Yanase, M.3    Narita, M.4    Kawabata, K.5    Sugita, M.6
  • 30
    • 0029888565 scopus 로고    scopus 로고
    • Comparative anatomical distribution of serotonin 1A, 1Dα and 2A receptor mRNAs in human brain postmortem
    • DOI 10.1016/0169-328X(96)00026-5
    • Pasqualetti M, Nardi I, Ladinsky H, Marazziti D, Cassano GB. Comparative anatomical distribution of serotonin 1A, 1D alpha and 2A receptor mRNAs in human brain postmortem. Brain Res Mol Brain Res 1996; 39: 223-233. (Pubitemid 26179162)
    • (1996) Molecular Brain Research , vol.39 , Issue.1-2 , pp. 223-233
    • Pasqualetti, M.1    Nardi, I.2    Ladinsky, H.3    Marazziti, D.4    Cassano, G.B.5
  • 31
    • 0034863766 scopus 로고    scopus 로고
    • Retinoic acid rescues inner ear defects in Hoxa1 deficient mice
    • DOI 10.1038/ng702
    • Pasqualetti M, Neun R, Davenne M, Rijli FM. Retinoic acid rescues inner ear defects in Hoxa1 deficient mice. Nat Genet 2001; 29: 34-39. (Pubitemid 32801805)
    • (2001) Nature Genetics , vol.29 , Issue.1 , pp. 34-39
    • Pasqualetti, M.1    Neun, R.2    Davenne, M.3    Rijli, F.M.4
  • 33
    • 0036198221 scopus 로고    scopus 로고
    • A Hoxa2 knockin allele that expresses EGFP upon conditional Cre-mediated recombination
    • DOI 10.1002/gene.10053
    • Pasqualetti M, Ren SY, Poulet M, LeMeur M, Dierich A, Rijli FM. A Hoxa2 knockin allele that expresses EGFP upon conditional Cre-mediated recombination. Genesis 2002; 32: 109-111. (Pubitemid 34211711)
    • (2002) Genesis , vol.32 , Issue.2 , pp. 109-111
    • Pasqualetti, M.1    Ren, S.-Y.2    Poulet, M.3    LeMeur, M.4    Dierich, A.5    Rijli, F.M.6
  • 34
    • 0010349883 scopus 로고
    • A method for the determination of plasma and blood volume
    • Keith NM, Rowntree LG, Geraghty JT. A METHOD FOR THE DETERMINATION OF PLASMA AND BLOOD VOLUME. Arch Intern Med 1915; 16: 547-557.
    • (1915) Arch Intern Med , vol.16 , pp. 547-557
    • Keith, N.M.1    Rowntree, L.G.2    Geraghty, J.T.3
  • 36
    • 0034121132 scopus 로고    scopus 로고
    • Sequential activation of the 5-Ht1(A) serotonin receptor and TrkB induces the serotonergic neuronal phenotype
    • DOI 10.1006/mcne.2000.0841
    • Galter D, Unsicker K. Sequential activation of the 5-HT1(A) serotonin receptor and TrkB induces the serotonergic neuronal phenotype. Mol Cell Neurosci 2000; 15: 446-455. (Pubitemid 30395369)
    • (2000) Molecular and Cellular Neurosciences , vol.15 , Issue.5 , pp. 446-455
    • Galter, D.1    Unsicker, K.2
  • 37
    • 0024421895 scopus 로고
    • Stimulation of astroglial serotonin receptors produces culture media which regulates growth of serotoninergic neurons
    • DOI 10.1016/0006-8993(89)90972-4
    • Whitaker-Azmitia PM, Azmitia EC. Stimulation of astroglial serotonin receptors produces culture media which regulates growth of serotonergic neurons. Brain Res 1989; 497: 80-85. (Pubitemid 19219913)
    • (1989) Brain Research , vol.497 , Issue.1 , pp. 80-85
    • Whitaker-Azmitia, P.M.1    Azmitia, E.C.2
  • 39
    • 0034651078 scopus 로고    scopus 로고
    • BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain
    • Mamounas LA, Altar CA, Blue ME, Kaplan DR, Tessarollo L, Lyons WE. BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain. J Neurosci 2000; 20: 771-782. (Pubitemid 30225579)
    • (2000) Journal of Neuroscience , vol.20 , Issue.2 , pp. 771-782
    • Mamounas, L.A.1    Altar, C.A.2    Blue, M.E.3    Kaplan, D.R.4    Tessarollo, L.5    Lyons, W.E.6
  • 40
    • 0029584365 scopus 로고
    • Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain
    • Mamounas LA, Blue ME, Siuciak JA, Altar CA. Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain. J Neurosci 1995; 15: 7929-7939. (Pubitemid 26006900)
    • (1995) Journal of Neuroscience , vol.15 , Issue.12 , pp. 7929-7939
    • Mamounas, L.A.1    Blue, M.E.2    Siuciak, J.A.3    Altar, C.A.4
  • 41
  • 42
    • 0024342864 scopus 로고
    • Altered branching of serotonin-containing neurons in Drosophila mutants unable to synthesize serotonin and dopamine
    • Budnik V, Wu CF, White K. Altered branching of serotonin-containing neurons in Drosophila mutants unable to synthesize serotonin and dopamine. J Neurosci 1989; 9: 2866-2877. (Pubitemid 19214319)
    • (1989) Journal of Neuroscience , vol.9 , Issue.8 , pp. 2866-2877
    • Budnik, V.1    Wu, C.-F.2    White, K.3
  • 43
    • 77956009908 scopus 로고    scopus 로고
    • Serotonin: A regulator of neuronal morphology and circuitry
    • Daubert EA, Condron BG. Serotonin: a regulator of neuronal morphology and circuitry. Trends Neurosci 2010; 33: 424-434.
    • (2010) Trends Neurosci , vol.33 , pp. 424-434
    • Daubert, E.A.1    Condron, B.G.2
  • 44
    • 0028816778 scopus 로고
    • Neurite branch development of an identified serotonergic neuron from embryonic Helisoma: Evidence for autoregulation by serotonin
    • Diefenbach TJ, Sloley BD, Goldberg JI. Neurite branch development of an identified serotonergic neuron from embryonic Helisoma: evidence for autoregulation by serotonin. Dev Biol 1995; 167: 282-293.
    • (1995) Dev Biol , vol.167 , pp. 282-293
    • Diefenbach, T.J.1    Sloley, B.D.2    Goldberg, J.I.3
  • 45
    • 0021192804 scopus 로고
    • Serotonin selectively inhibits growth cone motility and synaptogenesis of specific identified neurons
    • Haydon PG, McCobb DP, Kater SB. Serotonin selectively inhibits growth cone motility and synaptogenesis of specific identified neurons. Science 1984; 226: 561-564. (Pubitemid 14018532)
    • (1984) Science , vol.226 , Issue.4674 , pp. 561-564
    • Haydon, P.G.1    McCobb, D.P.2    Kater, S.B.3
  • 46
    • 0025094797 scopus 로고
    • 5-HT(1A) receptors control neurite branching during development
    • DOI 10.1016/0165-3806(90)90092-D
    • Sikich L, Hickok JM, Todd RD.5-HT1A receptors control neurite branching during development. Brain Res Dev Brain Res 1990; 56: 269-274. (Pubitemid 20364138)
    • (1990) Developmental Brain Research , vol.56 , Issue.2 , pp. 269-274
    • Sikich, L.1    Hickok, J.M.2    Todd, R.D.3
  • 47
    • 0034905785 scopus 로고    scopus 로고
    • 1B knockout
    • DOI 10.1046/j.1471-4159.2001.00437.x
    • Ase AR, Reader TA, Hen R, Riad M, Descarries L. Regional changes in density of serotonin transporter in the brain of 5-HT1A and 5-HT1B knockout mice, and of serotonin innervation in the 5-HT1B knockout. J Neurochem 2001; 78: 619-630. (Pubitemid 32729990)
    • (2001) Journal of Neurochemistry , vol.78 , Issue.3 , pp. 619-630
    • Ase, A.R.1    Reader, T.A.2    Hen, R.3    Riad, M.4    Descarries, L.5
  • 48
    • 71849103612 scopus 로고    scopus 로고
    • Chronic activation of the 5-HT(2) receptor reduces 5-HT neurite density as studied in organotypic slice cultures
    • Dudok JJ, Groffen AJ, Witter MP, Voorn P, Verhage M. Chronic activation of the 5-HT(2) receptor reduces 5-HT neurite density as studied in organotypic slice cultures. Brain Res 2009; 1302: 1-9.
    • (2009) Brain Res , vol.1302 , pp. 1-9
    • Dudok, J.J.1    Groffen, A.J.2    Witter, M.P.3    Voorn, P.4    Verhage, M.5
  • 49
    • 53149111135 scopus 로고    scopus 로고
    • Molecular biology of 5-HT receptors
    • Hannon J, Hoyer D. Molecular biology of 5-HT receptors. Behav Brain Res 2008; 195: 198-213.
    • (2008) Behav Brain Res , vol.195 , pp. 198-213
    • Hannon, J.1    Hoyer, D.2
  • 50
    • 33745991791 scopus 로고    scopus 로고
    • Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development
    • DOI 10.1016/j.neuroscience.2006.04.036, PII S0306452206004921
    • Bonnin A, Peng W, Hewlett W, Levitt P. Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development. Neuroscience 2006; 141: 781-794. (Pubitemid 44066651)
    • (2006) Neuroscience , vol.141 , Issue.2 , pp. 781-794
    • Bonnin, A.1    Peng, W.2    Hewlett, W.3    Levitt, P.4
  • 51
  • 53
    • 0342680006 scopus 로고    scopus 로고
    • Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant
    • DOI 10.1038/35000609
    • Sze JY, Victor M, Loer C, Shi Y, Ruvkun G. Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant. Nature 2000; 403: 560-564. (Pubitemid 30082203)
    • (2000) Nature , vol.403 , Issue.6769 , pp. 560-564
    • Szo, J.Y.1    Victor, M.2    Loer, C.3    Shi, Y.4    Ruvkun, G.5
  • 54
    • 0022558924 scopus 로고
    • Developmental of serotonin-containing neurons in Drosophila mutants unable to synthesize serotonin
    • Valles AM, White K. Development of serotonin-containing neurons in Drosophila mutants unable to synthesize serotonin. J Neurosci 1986; 6: 1482-1491. (Pubitemid 16078035)
    • (1986) Journal of Neuroscience , vol.6 , Issue.5 , pp. 1482-1491
    • Valles, A.M.1    White, K.2
  • 55
    • 79953041134 scopus 로고    scopus 로고
    • Brainderived neurotrophic factor expression is increased in the hippocampus of 5-HT(2C) receptor knockout mice
    • Hill RA, Murray SS, Halley PG, Binder MD, Martin SJ, van den Buuse M. Brainderived neurotrophic factor expression is increased in the hippocampus of 5-HT(2C) receptor knockout mice. Hippocampus 2011; 21: 434-445.
    • (2011) Hippocampus , vol.21 , pp. 434-445
    • Hill, R.A.1    Murray, S.S.2    Halley, P.G.3    Binder, M.D.4    Martin, S.J.5    Van Den Buuse, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.