Prolonged prenatal psychotropic medication exposure alters neonatal acute pain response

Pediatric Research

Volumn 51, Issue 4 I, 2002, Pages 443-453

  Oberlander, Tim F ^a   Grunau, Ruth Eckstein ^a   Fitzgerald, Colleen ^a   Ellwood, Ann Louise ^a   Misri, Shaila ^a   Rurak, Dan ^a   Riggs, Kenneth Wayne ^a  

^a Centre for Community Health and Health Evaluation Research   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE; CLONAZEPAM; FLUOXETINE; PAROXETINE; PSYCHOTROPIC AGENT; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

ARTICLE; AUTONOMIC NERVOUS SYSTEM; BREATHING; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG USE; FACE PAIN; FEMALE; HEART RATE VARIABILITY; HUMAN; INFANT; NOCICEPTION; PAIN ASSESSMENT; PHENYLKETONURIA; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; SYMPATHETIC TONE;

EID: 0036208580     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-200204000-00008     Document Type: Article

References (79)

1. Pharmacologic management of psychiatric illness during pregnancy: Dilemmas and guidelines
2. Serotonin as a developmental signal
3. Perinatal diazepam exposure: Behavioral and neurochemical consequences
4. Administration of tryptophan-enriched diets to pregnant rats retards the development of the serotonergic system in their offspring
5. Neurotransmitters as growth regulatory signals: Role of receptors and second messengers
6. Endogenous serotonin modulates the fetal respiratory rhythm: An in vitro study in the rat
7. GABA, benzodiazepine and serotonergic receptor development in the dorsal raphe nucleus: Electrophysiological studies
8. Prenatal ontogeny of the GABAergic system in the rat brain
9. Perinatal benzodiazepine modulation of GABAA receptor function: Influence on adaptive responses
10. Ontogeny of neurotransmitter systems: Substrates for developmental disabilities?
11. Pain in infancy: Some unanswered questions
12. Neonatal pharmacology of pain
13. The GABA paradox: Multiple roles as metabolite, neurotransmitter, and neurodifferentiative agent
14. Postnatal maturation of gamma-aminobutyric acid A and B-mediated inhibition in the CA3 hippocampal region of the rat
15. A developmental neurotoxicity evaluation of the effects of prenatal exposure to fluoxetine in rats
16. Prenatal exposure of rats to antidepressant drugs down-regulates beta-adrenoceptors and 5-HT2 receptors in cerebral cortex: Lack of correlation between 5-HT2 receptors and serotonin-mediated behaviour
17. Down-regulation of 3H-imipramine binding sites in rat cerebral cortex after prenatal exposure to antidepressants
18. Delayed Decreases in brain 5-hydroxytryptamine 2A/2C receptor density and function in male rat progeny following prenatal fluoxetine
19. Pregnancy outcome following first-trimester exposure to fluoxetine (Prozac)
20. Fluoxetine-exposed pregnancies
21. A case of lipomeningocele with fluoxetine (and alprazolam, vitamins B1 and B6, heptaminol) prescribed during pregnancy
22. In utero exposure to fluoxetine HCl increases hematoma frequency at birth
23. Neurodevelopment of children exposed in utero to antidepressant drugs
24. Outcome of children exposed in utero to fluoxetine: A critical review
25. Are the new SSRIs safe for pregnant women?
26. Fluoxetine hydrochloride (Prozac) toxicity in a neonate
27. Possible association between fluoxetine hydrochloride and colic in an infant
28. Neonatal withdrawal syndrome after in utero exposure to selective serotonin reuptake inhibitors
29. Birth outcomes following prenatal exposure to fluoxetine
30. Birth outcomes in pregnant women taking fluoxetine
31. The behavioral states of the newborn infant (a review)
32. Pain expression in neonates: Facial action and cry
33. Neonatal facial and cry responses to invasive and non-invasive procedures
34. Pain in the preterm neonate: Behavioural and physiological indices
35. Bedside application of the Neonatal Facial Coding System in pain assessment of premature neonates
36. The expression of pain in infants and toddlers: Developmental changes in facial action
37. Transfer function analysis of the circulation: Unique insights into cardiovascular regulation
38. The relation between neonatal heart period patterns and developmental outcome
39. Newborn pain cries and vagal tone: Parallel changes in response to circumcision
40. Time and frequency domain methods for heart rate variability analysis: A methodological comparison
41. Infants tolerate spinal anesthesia with minimal overall autonomic changes: Transfer function analysis of respiratory sinus arrhythmia in former premature infants undergoing hernia repair
42. Halothane causes withdrawal of cardiac sympathetic modulation in infants: Transfer function analysis of respiratory sinus arrhythmia
43. Transfer function analysis of respiratory sinus arrhythmia: Developmental changes in sleeping premature infants
44. Biobehavioral pain responses in former extremely low birth weight infants at four months' corrected age
45. Comparison of respiratory inductive plethysmography and thoracic impedance for apnea monitoring
46. An efficient algorithm for spectral analysis of heart rate variability
47. Transfer function analysis of autonomic regulation. I. Canine atrial rate response
48. Comparison of fetal and neonatal fluoxetine and paroxetine exposure during the perinatal period in humans
49. Pharmacokinetics of selective serotonin reuptake inhibitors
50. Excretion of paroxetine into breast milk
51. Sertraline and desmethylsertraline in human breast milk and nursing infants
52. Excretion of fluoxetine and its metabolite, norfluoxetine, in human breast milk
53. Physiology of lactation
54. The composition of human milk
55. Serum concentrations of antidepressants and benzodiazepines in nursing infants: A case series
56. Regulation of arousal and attention in preschool children exposed to cocaine prenatally
57. Prenatal exposure to fluoxetine (Prozac) produces site-specific and age-dependent alterations in brain serotonin transporters in rat progeny: Evidence from autoradiographic studies
58. Effect of prenatal fluoxetine (Prozac) exposure on brain serotonin in prepubescent and adult male rat offspring
59. Role of the 5-HT1A receptor in development of the neonatal rat brain: Preliminary behavioral studies
60. Role of the neurotropic properties of serotonin in the delay of brain maturation induced by cocaine
61. Prenatal cocaine exposure disrupts the development of the serotonergic system
62. Developing brain and in utero cocaine exposure: Effects on neural ontogeny
63. Facial expressivity to acute pain in cocaine exposed toddlers
64. Prenatal exposure to benzodiazepine-1. Prenatal exposure to lorazepam in mice alters open-field activity and GABAA receptor function
65. Enduring effects of prenatal diazepam on the behavior, EEG, and brain receptors of the adult cat progeny
66. Prenatal exposure to diazepam results in enduring reductions in brain receptors and deep slow wave sleep
67. Effects of prenatal exposure to benzodiazepine-related drugs on early development and adult social behaviour in Swiss mice, 1: Agonists
68. The effect of prenatal exposure to diazepam on aspects of postnatal development and behavior in rats
69. Benzodiazepines: Influence on the developing brain
70. Nervous and immune systems as targets for developmental effects of benzodiazepines. A review of recent studies
71. Selective effects on CRF neurons and catecholamine terminals in two stress-responsive regions of adult rat brain after prenatal exposure to diazepam
72. "Floppy infant syndrome" and maternal diazepam
73. Principles of drug biodisposition in the neonate. A critical evaluation of the pharmacokinetic-pharmacodynamic interface
74. Neonatal apnea associated with maternal clonazepam therapy: A case report
75. Possible neonatal diazepam withdrawal: A case report
76. Withdrawal symptoms in neonates form intrauterine exposure to diazepam
77. Effect of maternal lorazepam on the neonate
78. Long-term consequences of pain in human neonates
79. The regulation of sleep and arousal