Third trimester fetal heart rate and doppler middle cerebral artery blood flow velocity characteristics during prenatal selective serotonin reuptake inhibitor exposure

Pediatric Research

Volumn 70, Issue 1, 2011, Pages 96-101

  Rurak, Dan ^a,b   Lim, Ken ^a,b   Sanders, Ari ^b   Brain, Ursula ^a,b   Riggs, Wayne ^a   Oberlander, Tim F ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; CITALOPRAM; FLUOXETINE; PAROXETINE; QUETIAPINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRAZODONE; VENLAFAXINE;

ACCELERATION; ADULT; ARTICLE; BIRTH WEIGHT; BLOOD FLOW VELOCITY; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DOPPLER ECHOGRAPHY; FEMALE; FETUS HEART RATE; FETUS HYPOXIA; FETUS MOVEMENT; GESTATIONAL AGE; HAMILTON SCALE; HEAD CIRCUMFERENCE; HEART RATE VARIABILITY; HEMATOCRIT; HUMAN; INFANT; LONGITUDINAL STUDY; MATERNAL AGE; MIDDLE CEREBRAL ARTERY; MOOD DISORDER; NEWBORN; OBSERVATIONAL STUDY; PREGNANCY OUTCOME; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; SIDE EFFECT; SMOKING; THIRD TRIMESTER PREGNANCY; UMBILICAL ARTERY; UTERINE ARTERY; VASCULAR RESISTANCE;

ADULT; AFFECT; BRITISH COLUMBIA; CASE-CONTROL STUDIES; CEREBROVASCULAR CIRCULATION; CHI-SQUARE DISTRIBUTION; FEMALE; FETAL BLOOD; FETAL HEART; FETAL HYPOXIA; HEMATOCRIT; HEMOGLOBINS; HUMANS; MALE; MATERNAL EXPOSURE; MATERNAL-FETAL EXCHANGE; MIDDLE CEREBRAL ARTERY; MOOD DISORDERS; PREGNANCY; PREGNANCY TRIMESTER, THIRD; RISK ASSESSMENT; RISK FACTORS; SEROTONIN UPTAKE INHIBITORS; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL;

EID: 79960274560     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1203/PDR.0b013e31821ba11a     Document Type: Article

References (40)

1. Shadigian E, Bauer ST 2005 Pregnancy-associated death: a qualitative systematic review of homicide and suicide. Obstet Gynecol Surv 60:183-190 (Pubitemid 40315498)
2. Kinsella MT, Monk C 2009 Impact of maternal stress, depression and anxiety on fetal neurobehavioral development. Clin Obstet Gynecol 52:425-440
3. Oberlander TF, Gingrich JA, Ansorge MS 2009 Sustained neurobehavioral effects of exposure to SSRI antidepressants during development: molecular to clinical evidence. Clin Pharmacol Ther 86:672-677
4. Simon GE, Cunningham ML, Davis RL 2002 Outcomes of prenatal antidepressant exposure. Am J Psychiatry 159:2055-2061 (Pubitemid 35423865)
5. Moses-Kolko EL, Bogen D, Perel J, Bregar A, Uhl K, Levin B, Wisner KL 2005 Neonatal signs after late in utero exposure to serotonin reuptake inhibitors: literature review and implications for clinical applications. JAMA 293:2372-2383 (Pubitemid 40676760)
6. Oberlander TF, Eckstein GR, Fitzgerald C, Ellwood AL, Misri S, Rurak D, Riggs KW 2002 Prolonged prenatal psychotropic medication exposure alters neonatal acute pain response. Pediatr Res 51:443-453 (Pubitemid 34267314)
7. Zeskind PS, Stephens LE 2004 Maternal selective serotonin reuptake inhibitor use during pregnancy and newborn neurobehavior. Pediatrics 113:368-375 (Pubitemid 38177090)
8. Chambers CD, Hernandez-Diaz S, Van Marter LJ, Werler MM, Louik C, Jones KL, Mitchell AA 2006 Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn. N Engl J Med 354:579-587 (Pubitemid 43209105)
9. Fornaro E, Li D, Pan J, Belik J 2007 Prenatal exposure to fluoxetine induces fetal pulmonary hypertension in the rat. Am J Respir Crit Care Med 176:1035-1040 (Pubitemid 350127848)
10. Andrade SE, McPhillips H, Loren D, Raebel MA, Lane K, Livingston J, Boudreau DM, Smith DH, Davis RL, Willy ME, Platt R 2009 Antidepressant medication use and risk of persistent pulmonary hypertension of the newborn. Pharmacoepidemiol Drug Saf 18:246-252
11. Wichman CL, Fothergill A, Moore KM, Lang TR, Heise RH Jr, Watson WJ 2008 Recent trends in selective serotonin reuptake inhibitor use in pregnancy. J Clin Psychopharmacol 28:714-716
12. Laine K, Heikkinen T, Ekblad U, Kero P 2003 Effects of exposure to selective serotonin reuptake inhibitors during pregnancy on serotonergic symptoms in newborns and cord blood monoamine and prolactin concentrations. Arch Gen Psychiatry 60:720-726 (Pubitemid 36818634)
13. Richardson BS 1992 The effect of behavioral state on fetal metabolism and blood flow circulation. Semin Perinatol 16:227-233
14. Emory EK, Dieter JN 2006 Maternal depression and psychotropic medication effects on the human fetus. Ann N Y Acad Sci 1094:287-291 (Pubitemid 47092413)
15. Morrison JL, Chien C, Gruber N, Rurak D, Riggs W 2001 Fetal behavioural state changes following maternal fluoxetine infusion in sheep. Brain Res Dev Brain Res 131:47-56 (Pubitemid 33079217)
16. Morrison JL, Chien C, Riggs KW, Gruber N, Rurak D 2002 Effect of maternal fluoxetine administration on uterine blood flow, fetal blood gas status, and growth. Pediatr Res 51:433-442 (Pubitemid 34267313)
17. Morrison JL, Riggs KW, Chien C, Gruber N, McMillen IC, Rurak DW 2004 Chronic maternal fluoxetine infusion in pregnant sheep: effects on the maternal and fetal hypothalamic-pituitary-adrenal axes. Pediatr Res 56:40-46 (Pubitemid 38808541)
18. Richardson BS, Patrick JE, Abduljabbar H 1985 Cerebral oxidative metabolism in the fetal lamb: relationship to electrocortical state. Am J Obstet Gynecol 153:426-431 (Pubitemid 16216040)
19. Oberlander TF, Papsdorf M, Brain UM, Misri S, Ross C, Grunau RE 2010 Prenatal effects of selective serotonin reuptake inhibitor antidepressants, serotonin transporter promoter genotype (SLC6A4), and maternal mood on child behavior at 3 years of age. Arch Pediatr Adolesc Med 164:444-451
20. Hamilton M 1959 The assessment of anxiety states by rating. Br J Med Psychol 32:50-55
21. Erskine RL, Ritchie JW 1985 Quantitative measurement of fetal blood flow using Doppler ultrasound. Br J Obstet Gynaecol 92:600-604 (Pubitemid 15062614)
22. Dawes GS, Moulden M, Redman CW 1996 Improvements in computerized fetal heart rate analysis antepartum. J Perinat Med 24:25-36 (Pubitemid 26076113)
23. Chambers CD, Johnson KA, Dick LM, Felix RJ, Jones KL 1996 Birth outcomes in pregnant women taking fluoxetine. N Engl J Med 335:1010-1015 (Pubitemid 26338730)
24. Oberlander TF, Warburton W, Misri S, Aghajanian J, Hertzman C 2006 Neonatal outcomes after prenatal exposure to selective serotonin reuptake inhibitor antidepressants and maternal depression using population-based linked health data. Arch Gen Psychiatry 63:898-906 (Pubitemid 44188483)
25. Visser GH, Goodman JD, Levine DH, Dawes GS 1982 Diurnal and other cyclic variations in human fetal heart rate near term. Am J Obstet Gynecol 142:535-544 (Pubitemid 12192137)
26. Zemdegs IZ, McMillen IC, Walker DW, Thorburn GD, Nowak R 1988 Diurnal rhythms in plasma melatonin concentrations in the fetal sheep and pregnant ewe during late gestation. Endocrinology 123:284-289
27. Houghton DC, Walker DW, Young IR, McMillen IC 1993 Melatonin and the light-dark cycle separately influence daily behavioral and hormonal rhythms in the pregnant ewe and sheep fetus. Endocrinology 133:90-98 (Pubitemid 23206379)
28. Morin LP 1999 Serotonin and the regulation of mammalian circadian rhythmicity. Ann Med 31:12-33 (Pubitemid 29134482)
29. Morrison JL, Rurak DW, Chien C, Kennaway DJ, Gruber N, McMillen IC, Riggs KW 2005 Maternal fluoxetine infusion does not alter fetal endocrine and biophysical circadian rhythms in pregnant sheep. J Soc Gynecol Investig 12:356-364 (Pubitemid 40848460)
30. Baschat AA 2004 Fetal responses to placental insufficiency: an update. BJOG 111:1031-1041 (Pubitemid 39319260)
31. Hijazi ZR, East CE 2009 Factors affecting maternal perception of fetal movement. Obstet Gynecol Surv 64:489-497
32. Jensen EC, Bennet L, Guild SJ, Booth LC, Stewart J, Gunn AJ 2009 The role of the neural sympathetic and parasympathetic systems in diurnal and sleep state-related cardiovascular rhythms in the late-gestation ovine fetus. Am J Physiol Regul Integr Comp Physiol 297:R998-R1008
33. Gagnon R, Lamb T, Richardson B 1997 Cerebral circulatory responses of near-term ovine fetuses during sustained fetal placental embolization. Am J Physiol 273:H2001-H2008
34. Richardson BS, Bocking AD 1998 Metabolic and circulatory adaptations to chronic hypoxia in the fetus. Comp Biochem Physiol A Mol Integr Physiol 119:717-723 (Pubitemid 28219072)
35. Adair TH, Gay WJ, Montani JP 1990 Growth regulation of the vascular system: evidence for a metabolic hypothesis. Am J Physiol 259:R393-R404 (Pubitemid 20307558)
36. Teramo KA, Widness JA 2009 Increased fetal plasma and amniotic fluid erythropoietin concentrations: markers of intrauterine hypoxia. Neonatology 95:105-116
37. Ortiz J, Artigas F 1992 Effects of monoamine uptake inhibitors on extracellular and platelet 5-hydroxytryptamine in rat blood: different effects of clomipramine and fluoxetine. Br J Pharmacol 105:941-946
38. Morrison JL 2008 Sheep models of intrauterine growth restriction: fetal adaptations and consequences. Clin Exp Pharmacol Physiol 35:730-743 (Pubitemid 351725247)
39. Hodes GE, Hill-Smith TE, Suckow RF, Cooper TB, Lucki I 2010 Sex-specific effects of chronic fluoxetine treatment on neuroplasticity and pharmacokinetics in mice. J Pharmacol Exp Ther 332:266-273
40. Challis JRG, Matthews SG, Gibb W, Lye SJ 2000 Endocrine and paracrine regulation of birth at term and preterm. Endocr Rev 21:514-550