메뉴 건너뛰기




Volumn 4, Issue 9, 2016, Pages 1619-1632

Strategies for modulating innate immune activation and protein production of in vitro transcribed mRNAs

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; GENE THERAPY; GENE TRANSFER; GENES; PLANNING; VACCINES;

EID: 84959450353     PISSN: 20507518     EISSN: 2050750X     Source Type: Journal    
DOI: 10.1039/c5tb01753j     Document Type: Article
Times cited : (21)

References (122)
  • 1
    • 33749860977 scopus 로고    scopus 로고
    • Post-translational modifications in the context of therapeutic proteins
    • G. Walsh R. Jefferis Post-translational modifications in the context of therapeutic proteins Nat. Biotechnol. 2006 24 1241 1252
    • (2006) Nat. Biotechnol. , vol.24 , pp. 1241-1252
    • Walsh, G.1    Jefferis, R.2
  • 2
    • 84873406290 scopus 로고    scopus 로고
    • Systemic Delivery of Modified mRNA Encoding Herpes Simplex Virus 1 Thymidine Kinase for Targeted Cancer Gene Therapy
    • Y. H. Wang H. H. Su Y. Yang Y. X. Hu L. Zhang P. Blancafort L. Huang Systemic Delivery of Modified mRNA Encoding Herpes Simplex Virus 1 Thymidine Kinase for Targeted Cancer Gene Therapy Mol. Ther. 2013 21 358 367
    • (2013) Mol. Ther. , vol.21 , pp. 358-367
    • Wang, Y.H.1    Su, H.H.2    Yang, Y.3    Hu, Y.X.4    Zhang, L.5    Blancafort, P.6    Huang, L.7
  • 3
    • 0035412401 scopus 로고    scopus 로고
    • Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: Superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells
    • V. F. I. Van Tendeloo P. Ponsaerts F. Lardon G. Nijs M. Lenjou C. Van Broeckhoven D. R. Van Bockstaele Z. N. Berneman Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells Blood 2001 98 49 56
    • (2001) Blood , vol.98 , pp. 49-56
    • Van Tendeloo, V.F.I.1    Ponsaerts, P.2    Lardon, F.3    Nijs, G.4    Lenjou, M.5    Van Broeckhoven, C.6    Van Bockstaele, D.R.7    Berneman, Z.N.8
  • 4
    • 77649182625 scopus 로고    scopus 로고
    • Lipid-mediated delivery of RNA is more efficient than delivery of DNA in non-dividing cells
    • S. Zou K. Scarfo M. H. Nantz J. G. Hecker Lipid-mediated delivery of RNA is more efficient than delivery of DNA in non-dividing cells Int. J. Pharm. 2010 389 232 243
    • (2010) Int. J. Pharm. , vol.389 , pp. 232-243
    • Zou, S.1    Scarfo, K.2    Nantz, M.H.3    Hecker, J.G.4
  • 5
    • 84921794613 scopus 로고    scopus 로고
    • mRNA-based therapeutics - Developing a new class of drugs
    • U. Sahin K. Kariko O. Tureci mRNA-based therapeutics-developing a new class of drugs Nat. Rev. Drug Discovery 2014 13 759 780
    • (2014) Nat. Rev. Drug Discovery , vol.13 , pp. 759-780
    • Sahin, U.1    Kariko, K.2    Tureci, O.3
  • 6
    • 54949112814 scopus 로고    scopus 로고
    • Incorporation of Pseudouridine into mRNA Yields Superior Nonimmunogenic Vector with Increased Translational Capacity and Biological Stability
    • K. Kariko H. Muramatsu F. A. Welsh J. Ludwig H. Kato S. Akira D. Weissman Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability Mol. Ther. 2008 16 1833 1840
    • (2008) Mol. Ther. , vol.16 , pp. 1833-1840
    • Kariko, K.1    Muramatsu, H.2    Welsh, F.A.3    Ludwig, J.4    Kato, H.5    Akira, S.6    Weissman, D.7
  • 8
    • 84940720241 scopus 로고    scopus 로고
    • Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals
    • S. G. Andreas Thess B. L. Mui M. J. Hope P. Baumhof M. Fotin-Mleczek T. Schlake Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals Mol. Ther. 2015 23 1456 1464 10.1038/mt.2015
    • (2015) Mol. Ther. , vol.23 , pp. 1456-1464
    • Andreas Thess, S.G.1    Mui, B.L.2    Hope, M.J.3    Baumhof, P.4    Fotin-Mleczek, M.5    Schlake, T.6
  • 10
    • 82255194361 scopus 로고    scopus 로고
    • Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
    • K. Kariko H. Muramatsu J. Ludwig D. Weissman Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA Nucleic Acids Res. 2011 39 e142
    • (2011) Nucleic Acids Res. , vol.39 , pp. e142
    • Kariko, K.1    Muramatsu, H.2    Ludwig, J.3    Weissman, D.4
  • 12
    • 84860539841 scopus 로고    scopus 로고
    • Increased Erythropoiesis in Mice Injected with Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin
    • K. Kariko H. Muramatsu J. M. Keller D. Weissman Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin Mol. Ther. 2012 20 948 953
    • (2012) Mol. Ther. , vol.20 , pp. 948-953
    • Kariko, K.1    Muramatsu, H.2    Keller, J.M.3    Weissman, D.4
  • 13
    • 84885172335 scopus 로고    scopus 로고
    • Driving vascular endothelial cell fate of human multipotent Isl1+ heart progenitors with VEGF modified mRNA
    • K. O. Lui L. Zangi E. A. Silva L. Bu M. Sahara R. A. Li D. J. Mooney K. R. Chien Driving vascular endothelial cell fate of human multipotent Isl1+ heart progenitors with VEGF modified mRNA Cell Res. 2013 23 1172 1186
    • (2013) Cell Res. , vol.23 , pp. 1172-1186
    • Lui, K.O.1    Zangi, L.2    Silva, E.A.3    Bu, L.4    Sahara, M.5    Li, R.A.6    Mooney, D.J.7    Chien, K.R.8
  • 21
    • 2942559009 scopus 로고    scopus 로고
    • Cancer immunotherapy with mRNA-transfected dendritic cells
    • E. Gilboa J. Vieweg Cancer immunotherapy with mRNA-transfected dendritic cells Immunol. Rev. 2004 199 251 263
    • (2004) Immunol. Rev. , vol.199 , pp. 251-263
    • Gilboa, E.1    Vieweg, J.2
  • 22
    • 84997765983 scopus 로고    scopus 로고
    • Bridging infectious disease vaccines with cancer immunotherapy: A role for targeted RNA based immunotherapeutics
    • E. J. Sayour L. Sanchez-Perez C. Flores D. A. Mitchell Bridging infectious disease vaccines with cancer immunotherapy: a role for targeted RNA based immunotherapeutics J. Immunother. Cancer 2015 3 13
    • (2015) J. Immunother. Cancer , vol.3 , pp. 13
    • Sayour, E.J.1    Sanchez-Perez, L.2    Flores, C.3    Mitchell, D.A.4
  • 23
    • 54949148332 scopus 로고    scopus 로고
    • Diverse RNA-Binding Proteins Interact with Functionally Related Sets of RNAs, Suggesting an Extensive Regulatory System
    • D. J. Hogan D. P. Riordan A. P. Gerber D. Herschlag P. O. Brown Diverse RNA-Binding Proteins Interact with Functionally Related Sets of RNAs, Suggesting an Extensive Regulatory System PLoS Biol. 2008 6 2297 2313
    • (2008) PLoS Biol. , vol.6 , pp. 2297-2313
    • Hogan, D.J.1    Riordan, D.P.2    Gerber, A.P.3    Herschlag, D.4    Brown, P.O.5
  • 24
    • 84869090905 scopus 로고    scopus 로고
    • The Cellular EJC Interactome Reveals Higher-Order mRNP Structure and an EJC-SR Protein Nexus
    • G. Singh A. Kucukural C. Cenik J. D. Leszyk S. A. Shaffer Z. P. Weng M. J. Moore The Cellular EJC Interactome Reveals Higher-Order mRNP Structure and an EJC-SR Protein Nexus Cell 2012 151 750 764
    • (2012) Cell , vol.151 , pp. 750-764
    • Singh, G.1    Kucukural, A.2    Cenik, C.3    Leszyk, J.D.4    Shaffer, S.A.5    Weng, Z.P.6    Moore, M.J.7
  • 26
    • 77955326776 scopus 로고    scopus 로고
    • The Pioneer Round of Translation: Features and Functions
    • L. E. Maquat W. Y. Tarn O. Isken The Pioneer Round of Translation: Features and Functions Cell 2010 142 368 374
    • (2010) Cell , vol.142 , pp. 368-374
    • Maquat, L.E.1    Tarn, W.Y.2    Isken, O.3
  • 28
    • 0035404265 scopus 로고    scopus 로고
    • Translational control by CPEB: A means to the end
    • R. Mendez J. D. Richter Translational control by CPEB: a means to the end Nat. Rev. Mol. Cell Biol. 2001 2 521 529
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 521-529
    • Mendez, R.1    Richter, J.D.2
  • 29
    • 84862204864 scopus 로고    scopus 로고
    • The role of the 3′ untranslated region in post-transcriptional regulation of protein expression in mammalian cells
    • E. Matoulkova E. Michalova B. Vojtesek R. Hrstka The role of the 3′ untranslated region in post-transcriptional regulation of protein expression in mammalian cells RNA Biol. 2012 9 563 576
    • (2012) RNA Biol. , vol.9 , pp. 563-576
    • Matoulkova, E.1    Michalova, E.2    Vojtesek, B.3    Hrstka, R.4
  • 30
    • 84859632747 scopus 로고    scopus 로고
    • MiRNA-Mediated Gene Silencing by Translational Repression Followed by mRNA Deadenylation and Decay
    • S. Djuranovic A. Nahvi R. Green miRNA-Mediated Gene Silencing by Translational Repression Followed by mRNA Deadenylation and Decay Science 2012 336 237 240
    • (2012) Science , vol.336 , pp. 237-240
    • Djuranovic, S.1    Nahvi, A.2    Green, R.3
  • 33
    • 84884559601 scopus 로고    scopus 로고
    • Exogenous mRNA delivery and bioavailability in gene transfer mediated by piggyBac transposition
    • S. Bire D. Gosset G. Jegot P. Midoux C. Pichon F. Rouleux-Bonnin Exogenous mRNA delivery and bioavailability in gene transfer mediated by piggyBac transposition BMC Biotechnol. 2013 13 10.1186/1472-6750-13-75
    • (2013) BMC Biotechnol. , vol.13
    • Bire, S.1    Gosset, D.2    Jegot, G.3    Midoux, P.4    Pichon, C.5    Rouleux-Bonnin, F.6
  • 34
    • 39949085583 scopus 로고    scopus 로고
    • Stress granules: The Tao of RNA triage
    • P. Anderson N. Kedersha Stress granules: The Tao of RNA triage Trends Biochem. Sci. 2008 33 141 150
    • (2008) Trends Biochem. Sci. , vol.33 , pp. 141-150
    • Anderson, P.1    Kedersha, N.2
  • 35
  • 36
    • 36348940608 scopus 로고    scopus 로고
    • Interferons and viruses: An interplay between induction, signalling, antiviral responses and virus countermeasures
    • R. E. Randall S. Goodbourn Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures J. Gen. Virol. 2008 89 1 47
    • (2008) J. Gen. Virol. , vol.89 , pp. 1-47
    • Randall, R.E.1    Goodbourn, S.2
  • 38
    • 82255164455 scopus 로고    scopus 로고
    • Nucleoside modifications in RNA limit activation of 2′-5′-oligoadenylate synthetase and increase resistance to cleavage by RNase L
    • B. R. Anderson H. Muramatsu B. K. Jha R. H. Silverman D. Weissman K. Kariko Nucleoside modifications in RNA limit activation of 2′-5′-oligoadenylate synthetase and increase resistance to cleavage by RNase L Nucleic Acids Res. 2011 39 9329 9338
    • (2011) Nucleic Acids Res. , vol.39 , pp. 9329-9338
    • Anderson, B.R.1    Muramatsu, H.2    Jha, B.K.3    Silverman, R.H.4    Weissman, D.5    Kariko, K.6
  • 41
    • 78650640612 scopus 로고    scopus 로고
    • Messenger RNA-based Vaccines with Dual Activity Induce Balanced TLR-7 Dependent Adaptive Immune Responses and Provide Antitumor Activity
    • M. Fotin-Mleczek K. M. Duchardt C. Lorenz R. Pfeiffer S. Ojkic-Zrna J. Probst K. J. Kallen Messenger RNA-based Vaccines With Dual Activity Induce Balanced TLR-7 Dependent Adaptive Immune Responses and Provide Antitumor Activity J. Immunother. 2011 34 1 15
    • (2011) J. Immunother. , vol.34 , pp. 1-15
    • Fotin-Mleczek, M.1    Duchardt, K.M.2    Lorenz, C.3    Pfeiffer, R.4    Ojkic-Zrna, S.5    Probst, J.6    Kallen, K.J.7
  • 42
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • S. Akira K. Takeda T. Kaisho Toll-like receptors: critical proteins linking innate and acquired immunity Nat. Immunol. 2001 2 675 680
    • (2001) Nat. Immunol. , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 43
    • 84911489312 scopus 로고    scopus 로고
    • Activation of the RIG-I Pathway during Influenza Vaccination Enhances the Germinal Center Reaction, Promotes T Follicular Helper Cell Induction, and Provides a Dose-Sparing Effect and Protective Immunity
    • R. R. Kulkarni M. A. U. Rasheed S. K. Bhaumik P. Ranjan W. P. Cao C. Davis K. Marisetti S. Thomas S. Gangappa S. Sambhara et al., Activation of the RIG-I Pathway during Influenza Vaccination Enhances the Germinal Center Reaction, Promotes T Follicular Helper Cell Induction, and Provides a Dose-Sparing Effect and Protective Immunity J. Virol. 2014 88 13990 14001
    • (2014) J. Virol. , vol.88 , pp. 13990-14001
    • Kulkarni, R.R.1    Rasheed, M.A.U.2    Bhaumik, S.K.3    Ranjan, P.4    Cao, W.P.5    Davis, C.6    Marisetti, K.7    Thomas, S.8    Gangappa, S.9    Sambhara, S.10
  • 47
    • 79955017567 scopus 로고    scopus 로고
    • RNA helical imperfections regulate activation of the protein kinase PKR: Effects of bulge position, size, and geometry
    • L. A. Heinicke S. R. Nallagatla C. M. Hull P. C. Bevilacqua RNA helical imperfections regulate activation of the protein kinase PKR: effects of bulge position, size, and geometry Rna 2011 17 957 966
    • (2011) RNA , vol.17 , pp. 957-966
    • Heinicke, L.A.1    Nallagatla, S.R.2    Hull, C.M.3    Bevilacqua, P.C.4
  • 49
    • 36348987303 scopus 로고    scopus 로고
    • Viral encounters with 2′,5′-oligoadenylate synthetase and RNase L during the interferon antiviral response
    • R. H. Silverman Viral encounters with 2′,5′-oligoadenylate synthetase and RNase L during the interferon antiviral response J. Virol. 2007 81 12720 12729
    • (2007) J. Virol. , vol.81 , pp. 12720-12729
    • Silverman, R.H.1
  • 50
    • 84905123345 scopus 로고    scopus 로고
    • OAS proteins and cGAS: Unifying concepts in sensing and responding to cytosolic nucleic acids
    • V. Hornung R. Hartmann A. Ablasser K. P. Hopfner OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids Nat. Rev. Immunol. 2014 14 521 528
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 521-528
    • Hornung, V.1    Hartmann, R.2    Ablasser, A.3    Hopfner, K.P.4
  • 53
    • 84872604349 scopus 로고    scopus 로고
    • Structural Basis for dsRNA Recognition, Filament Formation, and Antiviral Signal Activation by MDA5
    • B. Wu A. Peisley C. Richards H. Yao X. H. Zeng C. Lin F. X. Chu T. Walz S. Hur Structural Basis for dsRNA Recognition, Filament Formation, and Antiviral Signal Activation by MDA5 Cell 2013 152 276 289
    • (2013) Cell , vol.152 , pp. 276-289
    • Wu, B.1    Peisley, A.2    Richards, C.3    Yao, H.4    Zeng, X.H.5    Lin, C.6    Chu, F.X.7    Walz, T.8    Hur, S.9
  • 55
    • 77954242369 scopus 로고    scopus 로고
    • The Chase for the RIG-I Ligand-Recent Advances
    • M. Schlee G. Hartmann The Chase for the RIG-I Ligand-Recent Advances Mol. Ther. 2010 18 1254 1262
    • (2010) Mol. Ther. , vol.18 , pp. 1254-1262
    • Schlee, M.1    Hartmann, G.2
  • 57
    • 84926104091 scopus 로고    scopus 로고
    • The Innate Immune Sensor LGP2 Activates Antiviral Signaling by Regulating MDA5-RNA Interaction and Filament Assembly
    • A. M. Bruns G. P. Leser R. A. Lamb C. M. Horvath The Innate Immune Sensor LGP2 Activates Antiviral Signaling by Regulating MDA5-RNA Interaction and Filament Assembly Mol. Cell 2014 55 771 781
    • (2014) Mol. Cell , vol.55 , pp. 771-781
    • Bruns, A.M.1    Leser, G.P.2    Lamb, R.A.3    Horvath, C.M.4
  • 59
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • S. S. Diebold T. Kaisho H. Hemmi S. Akira C. R. E. Sousa Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA Science 2004 303 1529 1531
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Sousa, C.R.E.5
  • 61
    • 65249092505 scopus 로고    scopus 로고
    • TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturation
    • A. Larange D. Antonios M. Pallardy S. Kerdine-Romer TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturation J. Leukocyte Biol. 2009 85 673 683
    • (2009) J. Leukocyte Biol. , vol.85 , pp. 673-683
    • Larange, A.1    Antonios, D.2    Pallardy, M.3    Kerdine-Romer, S.4
  • 66
    • 77953656943 scopus 로고    scopus 로고
    • TRNA Stabilization by Modified Nucleotides
    • Y. Motorin M. Helm tRNA Stabilization by Modified Nucleotides Biochemistry 2010 49 4934 4944
    • (2010) Biochemistry , vol.49 , pp. 4934-4944
    • Motorin, Y.1    Helm, M.2
  • 68
    • 84937514684 scopus 로고    scopus 로고
    • Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome
    • X. Z. X. Li S. Ma J. Song J. Bai F. Sun C. Yi Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome Nat. Chem. Biol. 2015 11 592 597
    • (2015) Nat. Chem. Biol. , vol.11 , pp. 592-597
    • Li, X.Z.X.1    Ma, S.2    Song, J.3    Bai, J.4    Sun, F.5    Yi, C.6
  • 69
    • 84922180958 scopus 로고    scopus 로고
    • Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells
    • T. M. Carlile M. F. Rojas-Duran B. Zinshteyn H. Shin K. M. Bartoli W. V. Gilbert Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells Nature 2014 515 143 146 10.1038/nature13802
    • (2014) Nature , vol.515 , pp. 143-146
    • Carlile, T.M.1    Rojas-Duran, M.F.2    Zinshteyn, B.3    Shin, H.4    Bartoli, K.M.5    Gilbert, W.V.6
  • 72
    • 80955130871 scopus 로고    scopus 로고
    • RNA nucleotide methylation
    • Y. Motorin M. Helm RNA nucleotide methylation Wires RNA 2011 2 611 631
    • (2011) Wires RNA , vol.2 , pp. 611-631
    • Motorin, Y.1    Helm, M.2
  • 73
    • 84874612971 scopus 로고    scopus 로고
    • Native Tertiary Structure and Nucleoside Modifications Suppress tRNA's Intrinsic Ability to Activate the Innate Immune Sensor PKR
    • S. R. Nallagatla C. N. Jones S. K. B. Ghosh S. D. Sharma C. E. Cameron L. L. Spremulli P. C. Bevilacqua Native Tertiary Structure and Nucleoside Modifications Suppress tRNA's Intrinsic Ability to Activate the Innate Immune Sensor PKR PLoS One 2013 8 e57905 10.1371/journal.pone.0057905
    • (2013) PLoS One , vol.8 , pp. e57905
    • Nallagatla, S.R.1    Jones, C.N.2    Ghosh, S.K.B.3    Sharma, S.D.4    Cameron, C.E.5    Spremulli, L.L.6    Bevilacqua, P.C.7
  • 74
    • 44149112583 scopus 로고    scopus 로고
    • Nucleoside modifications modulate activation of the protein kinase PKR in an RNA structure-specific manner
    • S. R. Nallagatla P. C. Bevilacqua Nucleoside modifications modulate activation of the protein kinase PKR in an RNA structure-specific manner RNA 2008 14 1201 1213
    • (2008) RNA , vol.14 , pp. 1201-1213
    • Nallagatla, S.R.1    Bevilacqua, P.C.2
  • 77
    • 79959284255 scopus 로고    scopus 로고
    • Converting nonsense codons into sense codons by targeted pseudouridylation
    • J. Karijolich Y. T. Yu Converting nonsense codons into sense codons by targeted pseudouridylation Nature 2011 474 395 398
    • (2011) Nature , vol.474 , pp. 395-398
    • Karijolich, J.1    Yu, Y.T.2
  • 78
    • 84857398178 scopus 로고    scopus 로고
    • Rationalization and prediction of selective decoding of pseudouridine-modified nonsense and sense codons
    • M. Parisien C. Yi T. Pan Rationalization and prediction of selective decoding of pseudouridine-modified nonsense and sense codons RNA 2012 18 355 367
    • (2012) RNA , vol.18 , pp. 355-367
    • Parisien, M.1    Yi, C.2    Pan, T.3
  • 81
    • 78049403925 scopus 로고    scopus 로고
    • Synonymous codon usage influences the local protein structure observed
    • R. Saunders C. M. Deane Synonymous codon usage influences the local protein structure observed Nucleic Acids Res. 2010 38 6719 6728
    • (2010) Nucleic Acids Res. , vol.38 , pp. 6719-6728
    • Saunders, R.1    Deane, C.M.2
  • 82
    • 78650304100 scopus 로고    scopus 로고
    • Synonymous but not the same: The causes and consequences of codon bias
    • J. B. Plotkin G. Kudla Synonymous but not the same: the causes and consequences of codon bias Nat. Rev. Genet. 2011 12 32 42
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 32-42
    • Plotkin, J.B.1    Kudla, G.2
  • 83
    • 48649107858 scopus 로고    scopus 로고
    • Quantitative Effect of Suboptimal Codon Usage on Translational Efficiency of mRNA Encoding HIV-1 gag in Intact T Cells
    • K. C. Ngumbela K. P. Ryan R. Sivamurthy M. A. Brockman R. T. Gandhi N. Bhardwaj D. G. Kavanagh Quantitative Effect of Suboptimal Codon Usage on Translational Efficiency of mRNA Encoding HIV-1 gag in Intact T Cells PLoS One 2008 3 e2356 10.1371/journal.pone.0002356
    • (2008) PLoS One , vol.3 , pp. e2356
    • Ngumbela, K.C.1    Ryan, K.P.2    Sivamurthy, R.3    Brockman, M.A.4    Gandhi, R.T.5    Bhardwaj, N.6    Kavanagh, D.G.7
  • 84
    • 84876044227 scopus 로고    scopus 로고
    • mRNA secondary structure optimization using a correlated stem-loop prediction
    • P. Gaspar G. Moura M. A. S. Santos J. L. Oliveira mRNA secondary structure optimization using a correlated stem-loop prediction Nucleic Acids Res. 2013 41 e73 10.1093/nar/gks1473
    • (2013) Nucleic Acids Res. , vol.41 , pp. e73
    • Gaspar, P.1    Moura, G.2    Santos, M.A.S.3    Oliveira, J.L.4
  • 85
    • 0038463475 scopus 로고    scopus 로고
    • Effects of codon usage versus putative 5′-mRNA structure on the expression of Fusarium solani cutinase in the Escherichia coli cytoplasm
    • K. E. Griswold N. A. Mahmood B. L. Iverson G. Georgiou Effects of codon usage versus putative 5′-mRNA structure on the expression of Fusarium solani cutinase in the Escherichia coli cytoplasm Protein Expression Purif. 2003 27 134 142
    • (2003) Protein Expression Purif. , vol.27 , pp. 134-142
    • Griswold, K.E.1    Mahmood, N.A.2    Iverson, B.L.3    Georgiou, G.4
  • 86
    • 33748316617 scopus 로고    scopus 로고
    • mRNA secondary structure at start AUG codon is a key limiting factor for human protein expression in Escherichia coli
    • W. C. Zhang W. H. Xiao H. M. Wei J. Zhang Z. G. Tian mRNA secondary structure at start AUG codon is a key limiting factor for human protein expression in Escherichia coli Biochem. Biophys. Res. Commun. 2006 349 69 78
    • (2006) Biochem. Biophys. Res. Commun. , vol.349 , pp. 69-78
    • Zhang, W.C.1    Xiao, W.H.2    Wei, H.M.3    Zhang, J.4    Tian, Z.G.5
  • 87
    • 79952289327 scopus 로고    scopus 로고
    • Multiparameter RNA and Codon Optimization: A Standardized Tool to Assess and Enhance Autologous Mammalian Gene Expression
    • S. Fath A. P. Bauer M. Liss A. Spriestersbach B. Maertens P. Hahn C. Ludwig F. Schafer M. Graf R. Wagner Multiparameter RNA and Codon Optimization: A Standardized Tool to Assess and Enhance Autologous Mammalian Gene Expression PLoS One 2011 6 e17596 10.1371/journal.pone.0017596
    • (2011) PLoS One , vol.6 , pp. e17596
    • Fath, S.1    Bauer, A.P.2    Liss, M.3    Spriestersbach, A.4    Maertens, B.5    Hahn, P.6    Ludwig, C.7    Schafer, F.8    Graf, M.9    Wagner, R.10
  • 89
    • 31144465926 scopus 로고    scopus 로고
    • Hearing silence: Non-neutral evolution at synonymous sites in mammals
    • J. V. Chamary J. L. Parmley L. D. Hurst Hearing silence: non-neutral evolution at synonymous sites in mammals Nat. Rev. Genet. 2006 7 98 108
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 98-108
    • Chamary, J.V.1    Parmley, J.L.2    Hurst, L.D.3
  • 90
    • 0025297285 scopus 로고
    • Codon Preferences in Free-Living Microorganisms
    • S. G. E. Andersson C. G. Kurland Codon Preferences in Free-Living Microorganisms Microbiol. Rev. 1990 54 198 210
    • (1990) Microbiol. Rev. , vol.54 , pp. 198-210
    • Andersson, S.G.E.1    Kurland, C.G.2
  • 91
    • 33845497677 scopus 로고    scopus 로고
    • Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells
    • S. Holtkamp S. Kreiter A. Selmi P. Simon M. Koslowski C. Huber O. Tureci U. Sahin Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells Blood 2006 108 4009 4017
    • (2006) Blood , vol.108 , pp. 4009-4017
    • Holtkamp, S.1    Kreiter, S.2    Selmi, A.3    Simon, P.4    Koslowski, M.5    Huber, C.6    Tureci, O.7    Sahin, U.8
  • 93
    • 84960209149 scopus 로고    scopus 로고
    • Evading innate immunity in nonviral mRNA delivery: Don't shoot the messenger
    • J. Devoldere H. Dewitte S. C. De Smedt K. Remaut Evading innate immunity in nonviral mRNA delivery: don't shoot the messenger Drug Discovery Today 2015 10.1016/j.drudis.2015.07.009
    • (2015) Drug Discovery Today
    • Devoldere, J.1    Dewitte, H.2    De Smedt, S.C.3    Remaut, K.4
  • 95
    • 84921357504 scopus 로고    scopus 로고
    • Lipid-based mRNA vaccine delivery systems
    • P. Midoux C. Pichon Lipid-based mRNA vaccine delivery systems Expert Rev. Vaccines 2015 14 221 234
    • (2015) Expert Rev. Vaccines , vol.14 , pp. 221-234
    • Midoux, P.1    Pichon, C.2
  • 97
    • 65649094047 scopus 로고    scopus 로고
    • Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent (vol 14, pg 1175, 2007)
    • J. Probst B. Weide B. Scheel B. J. Pichler I. Hoerr H. G. Rammensee S. Pascolo Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent (vol 14, pg 1175, 2007) Gene Ther. 2009 16 706
    • (2009) Gene Ther. , vol.16 , pp. 706
    • Probst, J.1    Weide, B.2    Scheel, B.3    Pichler, B.J.4    Hoerr, I.5    Rammensee, H.G.6    Pascolo, S.7
  • 98
    • 84873477636 scopus 로고    scopus 로고
    • Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format
    • K. K. L. Phua K. W. Leong S. K. Nair Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format J. Controlled Release 2013 166 227 233
    • (2013) J. Controlled Release , vol.166 , pp. 227-233
    • Phua, K.K.L.1    Leong, K.W.2    Nair, S.K.3
  • 100
    • 67349185334 scopus 로고    scopus 로고
    • High performance mRNA transfection through carbonate apatite-cationic liposome conjugates
    • F. T. Zohra E. H. Chowdhury T. Akaike High performance mRNA transfection through carbonate apatite-cationic liposome conjugates Biomaterials 2009 30 4006 4013
    • (2009) Biomaterials , vol.30 , pp. 4006-4013
    • Zohra, F.T.1    Chowdhury, E.H.2    Akaike, T.3
  • 101
    • 84902097227 scopus 로고    scopus 로고
    • Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity
    • K. K. L. Phua H. F. Staats K. W. Leong S. K. Nair Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity Sci. Rep. 2014 4 5128 10.1038/srep05128
    • (2014) Sci. Rep. , vol.4 , pp. 5128
    • Phua, K.K.L.1    Staats, H.F.2    Leong, K.W.3    Nair, S.K.4
  • 102
    • 0037429077 scopus 로고    scopus 로고
    • Stability of mRNA/cationic lipid lipoplexes in human and rat cerebrospinal fluid: Methods and evidence for nonviral mRNA gene delivery to the central nervous system
    • D. M. Anderson L. L. Hall A. R. Ayyalapu V. R. Irion M. H. Nantz J. G. Hecker Stability of mRNA/cationic lipid lipoplexes in human and rat cerebrospinal fluid: Methods and evidence for nonviral mRNA gene delivery to the central nervous system Hum. Gene Ther. 2003 14 191 202
    • (2003) Hum. Gene Ther. , vol.14 , pp. 191-202
    • Anderson, D.M.1    Hall, L.L.2    Ayyalapu, A.R.3    Irion, V.R.4    Nantz, M.H.5    Hecker, J.G.6
  • 103
    • 79958296153 scopus 로고    scopus 로고
    • In Vitro and in Vivo mRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles
    • X. F. Su J. Fricke D. G. Kavanagh D. J. Irvine In Vitro and in Vivo mRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles Mol. Pharmaceutics 2011 8 774 787
    • (2011) Mol. Pharmaceutics , vol.8 , pp. 774-787
    • Su, X.F.1    Fricke, J.2    Kavanagh, D.G.3    Irvine, D.J.4
  • 107
    • 84864021234 scopus 로고    scopus 로고
    • Multifunctional triblock copolymers for intracellular messenger RNA delivery
    • C. Cheng A. J. Convertine P. S. Stayton J. D. Bryers Multifunctional triblock copolymers for intracellular messenger RNA delivery Biomaterials 2012 33 6868 6876
    • (2012) Biomaterials , vol.33 , pp. 6868-6876
    • Cheng, C.1    Convertine, A.J.2    Stayton, P.S.3    Bryers, J.D.4
  • 109
    • 79960725328 scopus 로고    scopus 로고
    • Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA
    • F. Perche T. Benvegnu M. Berchel L. Lebegue C. Pichon P. A. Jaffres P. Midoux Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA J. Nanomed. Nanotechnol. 2011 7 445 453
    • (2011) J. Nanomed. Nanotechnol. , vol.7 , pp. 445-453
    • Perche, F.1    Benvegnu, T.2    Berchel, M.3    Lebegue, L.4    Pichon, C.5    Jaffres, P.A.6    Midoux, P.7
  • 111
    • 85031984180 scopus 로고    scopus 로고
    • Baumhover and Rice. Efficient expression of stabilized mRNA PEG-peptide polyplexes in liver
    • P. Crowley Baumhover and Rice. Efficient expression of stabilized mRNA PEG-peptide polyplexes in liver Gene Ther. 2015 10.1038/mt.2010.289
    • (2015) Gene Ther.
    • Crowley, P.1
  • 113
    • 84913602317 scopus 로고    scopus 로고
    • Immunogenicity of Intradermal Trivalent Influenza Vaccine with Topical Imiquimod: A Double Blind Randomized Controlled Trial
    • I. F. N. Hung A. J. Zhang K. K. W. To J. F. W. Chan C. Li H. S. Zhu P. Li C. Li T. C. Chan V. C. C. Cheng et al., Immunogenicity of Intradermal Trivalent Influenza Vaccine With Topical Imiquimod: A Double Blind Randomized Controlled Trial Clin. Infect. Dis. 2014 59 1246 1255
    • (2014) Clin. Infect. Dis. , vol.59 , pp. 1246-1255
    • Hung, I.F.N.1    Zhang, A.J.2    To, K.K.W.3    Chan, J.F.W.4    Li, C.5    Zhu, H.S.6    Li, P.7    Li, C.8    Chan, T.C.9    Cheng, V.C.C.10
  • 114
    • 78549283854 scopus 로고    scopus 로고
    • Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity
    • S. Kreiter A. Selmi M. Diken M. Koslowski C. M. Britten C. Huber O. Tureci U. Sahin Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity Cancer Res. 2010 70 9031 9040
    • (2010) Cancer Res. , vol.70 , pp. 9031-9040
    • Kreiter, S.1    Selmi, A.2    Diken, M.3    Koslowski, M.4    Britten, C.M.5    Huber, C.6    Tureci, O.7    Sahin, U.8
  • 115
    • 55949126429 scopus 로고    scopus 로고
    • Clearance properties of nano-sized particles and molecules as imaging agents: Considerations and caveats
    • M. Longmire P. L. Choyke H. Kobayashi Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats Nanomedicine 2008 3 703 717
    • (2008) Nanomedicine , vol.3 , pp. 703-717
    • Longmire, M.1    Choyke, P.L.2    Kobayashi, H.3
  • 116
    • 0030864266 scopus 로고    scopus 로고
    • A low rate of cell proliferation and reduced DNA uptake limit cationic lipid-mediated gene transfer to primary cultures of ciliated human airway epithelia
    • A. Fasbender J. Zabner B. G. Zeiher M. J. Welsh A low rate of cell proliferation and reduced DNA uptake limit cationic lipid-mediated gene transfer to primary cultures of ciliated human airway epithelia Gene Ther. 1997 4 1173 1180
    • (1997) Gene Ther. , vol.4 , pp. 1173-1180
    • Fasbender, A.1    Zabner, J.2    Zeiher, B.G.3    Welsh, M.J.4
  • 117
    • 0031013538 scopus 로고    scopus 로고
    • Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells
    • H. Matsui L. G. Johnson S. H. Randell R. C. Boucher Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells J. Biol. Chem. 1997 272 1117 1126
    • (1997) J. Biol. Chem. , vol.272 , pp. 1117-1126
    • Matsui, H.1    Johnson, L.G.2    Randell, S.H.3    Boucher, R.C.4
  • 118
    • 33847099637 scopus 로고    scopus 로고
    • Lipid-based nanoparticles for nucleic acid delivery
    • W. J. Li F. C. Szoka Lipid-based nanoparticles for nucleic acid delivery Pharm. Res. 2007 24 438 449
    • (2007) Pharm. Res. , vol.24 , pp. 438-449
    • Li, W.J.1    Szoka, F.C.2
  • 120
    • 84871800573 scopus 로고    scopus 로고
    • Quantifying RNA-protein interactions in situ using modified-MTRIPs and proximity ligation
    • J. Jung A. W. Lifland C. Zurla E. J. Alonas P. J. Santangelo Quantifying RNA-protein interactions in situ using modified-MTRIPs and proximity ligation Nucleic Acids Res. 2013 41 e12 10.1093/nar/gks837
    • (2013) Nucleic Acids Res. , vol.41 , pp. e12
    • Jung, J.1    Lifland, A.W.2    Zurla, C.3    Alonas, E.J.4    Santangelo, P.J.5
  • 121
    • 84892999996 scopus 로고    scopus 로고
    • Methods for comprehensive experimental identification of RNA-protein interactions
    • C. A. McHugh P. Russell M. Guttman Methods for comprehensive experimental identification of RNA-protein interactions Genome Biol. 2014 15 10.1186/gb4152
    • (2014) Genome Biol. , vol.15
    • McHugh, C.A.1    Russell, P.2    Guttman, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.