Antiviral Activity of Human OASL Protein Is Mediated by Enhancing Signaling of the RIG-I RNA Sensor

Immunity

Volumn 40, Issue 6, 2014, Pages 936-948

  Zhu, Jianzhong ^a,b   Zhang, Yugen ^a,b   Ghosh, Arundhati ^a,b   Cuevas, Rolando A ^a,b   Forero, Adriana ^a,b   Dhar, Jayeeta ^c   Ibsen, MikkelSøes ^d   Schmid Burgk, JonathanLeo ^e   Schmidt, Tobias ^e   Ganapathiraju, Madhavi K ^b   Fujita, Takashi ^f   Hartmann, Rune ^d   Barik, Sailen ^c   Hornung, Veit ^e   Coyne, Carolyn B ^a,b   Sarkar, Saumendra N ^a,b  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c Department of Biological   (United States)

^d AARHUS UNIVERSITY   (Denmark)

^e UNIVERSITY OF BONN   (Germany)

^f KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; INTERFERON; OASL1 PROTEIN; OASL2 PROTEIN; OLIGOADENYLATE SYNTHETASES LIKE PROTEIN; POLYUBIQUITIN; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG; VIRUS RNA;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INTERFERON INDUCTION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

2',5'-OLIGOADENYLATE SYNTHETASE; ANIMALS; DEAD-BOX RNA HELICASES; DNA VIRUS INFECTIONS; HCT116 CELLS; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-7; INTERFERON TYPE I; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYUBIQUITIN; PROTEIN BINDING; RNA INTERFERENCE; RNA VIRUS INFECTIONS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

EID: 84902829130     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2014.05.007     Document Type: Article

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