-
1
-
-
34347250824
-
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: Role of lipid phosphate phosphatase-1 and sphingosine kinase 1
-
Zhao Y, Kalari SK, Usatyuk PV, Gorshkova I, He D, et al. 2007. Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. J. Biol. Chem. 282:14165-77
-
(2007)
J. Biol. Chem
, vol.282
, pp. 14165-14177
-
-
Zhao, Y.1
Kalari, S.K.2
Usatyuk, P.V.3
Gorshkova, I.4
He, D.5
-
2
-
-
84877753914
-
Ceramide synthases expression and role of ceramide synthase-2 in the lung: Insight from human lung cells and mouse models
-
Petrache I, Kamocki K, PoirierC,Pewzner-JungY,Laviad EL, et al. 2013. Ceramide synthases expression and role of ceramide synthase-2 in the lung: insight from human lung cells and mouse models. PLOS ONE 8:e62968
-
(2013)
PLOS ONE
, vol.8
, pp. e62968
-
-
Petrache, I.1
Kamocki, K.2
Poirier, C.3
Pewzner-Jung, Y.4
Laviad, E.L.5
-
3
-
-
24944460384
-
LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia
-
Xu Z, Zhou J, McCoyDM, Mallampalli RK. 2005. LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia. J. Lipid Res. 46:1229-38
-
(2005)
J. Lipid Res
, vol.46
, pp. 1229-1238
-
-
Xu, Z.1
Zhou, J.2
McCoy, D.M.3
Mallampalli, R.K.4
-
4
-
-
84871608339
-
Neutral sphingomyelinase 2 deficiency is associated with lung anomalies similar to emphysema
-
Poirier C, Berdyshev EV, Dimitropoulou C, Bogatcheva NV, Biddinger PW, Verin AD. 2012. Neutral sphingomyelinase 2 deficiency is associated with lung anomalies similar to emphysema. Mamm. Genome 23:758-63
-
(2012)
Mamm. Genome
, vol.23
, pp. 758-763
-
-
Poirier, C.1
Berdyshev, E.V.2
Dimitropoulou, C.3
Bogatcheva, N.V.4
Biddinger, P.W.5
Verin, A.D.6
-
6
-
-
79957610938
-
The outs and the ins of sphingosine-1-phosphate in immunity
-
Spiegel S, Milstien S. 2011. The outs and the ins of sphingosine-1-phosphate in immunity. Nat. Rev. Immunol. 11:403-15
-
(2011)
Nat. Rev. Immunol
, vol.11
, pp. 403-415
-
-
Spiegel, S.1
Milstien, S.2
-
7
-
-
21844457949
-
Sphingosine 1-phosphate and its receptors: An autocrine and paracrine network
-
Rosen H, Goetzl EJ. 2005. Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network. Nat. Rev. Immunol. 5:560-70
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 560-570
-
-
Rosen, H.1
Goetzl, E.J.2
-
8
-
-
84893496597
-
Effects of lipid interactions on model vesicle engulfment by alveolar macrophages
-
Justice MJ, Petrusca DN, Rogozea AL, Williams JA, Schweitzer KS, et al. 2014. Effects of lipid interactions on model vesicle engulfment by alveolar macrophages. Biophys. J. 106:598-609
-
(2014)
Biophys. J
, vol.106
, pp. 598-609
-
-
Justice, M.J.1
Petrusca, D.N.2
Rogozea, A.L.3
Williams, J.A.4
Schweitzer, K.S.5
-
9
-
-
84891350435
-
Changes in membrane biophysical properties induced by sphingomyelinase depend on the sphingolipid N-acyl chain
-
Pinto SN, Laviad EL, Stiban J, Kelly SL, Merrill AH Jr, et al. 2014. Changes in membrane biophysical properties induced by sphingomyelinase depend on the sphingolipid N-acyl chain. J. Lipid Res. 55:53-61
-
(2014)
J. Lipid Res
, vol.55
, pp. 53-61
-
-
Pinto, S.N.1
Laviad, E.L.2
Stiban, J.3
Kelly, S.L.4
Merrill, A.H.5
-
10
-
-
38549152194
-
Principles of bioactive lipid signalling: Lessons from sphingolipids
-
Hannun YA, Obeid LM. 2008. Principles of bioactive lipid signalling: lessons from sphingolipids. Nat. Rev. Mol. Cell Biol. 9:139-50
-
(2008)
Nat. Rev. Mol. Cell Biol
, vol.9
, pp. 139-150
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
11
-
-
84939950653
-
Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis
-
Peng H, Li C, Kadow S, Henry BD, Steinmann J, et al. 2015. Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis. J. Mol. Med. 93:675-89
-
(2015)
J. Mol. Med
, vol.93
, pp. 675-689
-
-
Peng, H.1
Li, C.2
Kadow, S.3
Henry, B.D.4
Steinmann, J.5
-
12
-
-
0030784482
-
Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation
-
Haimovitz-Friedman A, Cordon-Cardo C, Bayoumy S, Garzotto M, McLoughlin M, et al. 1997. Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation. J. Exp. Med. 186:1831-41
-
(1997)
J. Exp. Med
, vol.186
, pp. 1831-1841
-
-
Haimovitz-Friedman, A.1
Cordon-Cardo, C.2
Bayoumy, S.3
Garzotto, M.4
McLoughlin, M.5
-
13
-
-
11144354259
-
PAF-mediated pulmonary edema: A new role for acid sphingomyelinase and ceramide
-
Goggel R,Winoto-Morbach S, Vielhaber G, Imai Y, Lindner K, et al. 2004. PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide. Nat. Med. 10:155-60
-
(2004)
Nat. Med
, vol.10
, pp. 155-160
-
-
Goggel, R.1
Winoto-Morbach, S.2
Vielhaber, G.3
Imai, Y.4
Lindner, K.5
-
15
-
-
80055079168
-
Dihydroceramide-based response to hypoxia
-
Devlin CM, Lahm T, Hubbard WC, Van Demark M, Wang KC, et al. 2011. Dihydroceramide-based response to hypoxia. J. Biol. Chem. 286:38069-78
-
(2011)
J. Biol. Chem
, vol.286
, pp. 38069-38078
-
-
Devlin, C.M.1
Lahm, T.2
Hubbard, W.C.3
Van Demark, M.4
Wang, K.C.5
-
16
-
-
77952927745
-
Vascular barrier regulation by PAF, ceramide, caveolae, and NO-an intricate signaling network with discrepant effects in the pulmonary and systemic vasculature
-
KueblerWM, Yang Y, Samapati R, Uhlig S. 2010. Vascular barrier regulation by PAF, ceramide, caveolae, and NO-an intricate signaling network with discrepant effects in the pulmonary and systemic vasculature. Cell. Physiol. Biochem. 26:29-40
-
(2010)
Cell. Physiol. Biochem
, vol.26
, pp. 29-40
-
-
Kuebler, W.M.1
Yang, Y.2
Samapati, R.3
Uhlig, S.4
-
17
-
-
84856019712
-
Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by acid sphingomyelinase and transient receptor potential classical 6
-
Samapati R, Yang Y, Yin J, Stoerger C, Arenz C, et al. 2012. Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by acid sphingomyelinase and transient receptor potential classical 6. Am. J. Respir. Crit. Care Med. 185:160-70
-
(2012)
Am. J. Respir. Crit. Care Med
, vol.185
, pp. 160-170
-
-
Samapati, R.1
Yang, Y.2
Yin, J.3
Stoerger, C.4
Arenz, C.5
-
18
-
-
80052478316
-
Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact
-
Presson RG Jr, Brown MB, Fisher AJ, Sandoval RM, Dunn KW, et al. 2011. Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact. Am. J. Pathol. 179:75-82
-
(2011)
Am. J. Pathol
, vol.179
, pp. 75-82
-
-
Presson, R.G.1
Brown, M.B.2
Fisher, A.J.3
Sandoval, R.M.4
Dunn, K.W.5
-
19
-
-
84883176854
-
Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury
-
Natarajan V, Dudek SM, Jacobson JR, Moreno-Vinasco L, Huang LS, et al. 2013. Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury. Am. J. Respir. Cell Mol. Biol. 49:6-17
-
(2013)
Am. J. Respir. Cell Mol. Biol
, vol.49
, pp. 6-17
-
-
Natarajan, V.1
Dudek, S.M.2
Jacobson, J.R.3
Moreno-Vinasco, L.4
Huang, L.S.5
-
20
-
-
79959340773
-
Endotheliumprotective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M
-
Christoffersen C, Obinata H, Kumaraswamy SB, Galvani S, Ahnstrom J, et al. 2011. Endotheliumprotective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M. PNAS 108:9613-18
-
(2011)
PNAS
, vol.108
, pp. 9613-9618
-
-
Christoffersen, C.1
Obinata, H.2
Kumaraswamy, S.B.3
Galvani, S.4
Ahnstrom, J.5
-
21
-
-
56049110035
-
Sphingosine 1-phosphate rescues canine LPS-induced acute lung injury and alters systemic inflammatory cytokine production in vivo
-
Szczepaniak WS, Zhang Y, Hagerty S, Crow MT, Kesari P, et al. 2008. Sphingosine 1-phosphate rescues canine LPS-induced acute lung injury and alters systemic inflammatory cytokine production in vivo. Transl. Res. 152:213-24
-
(2008)
Transl. Res
, vol.152
, pp. 213-224
-
-
Szczepaniak, W.S.1
Zhang, Y.2
Hagerty, S.3
Crow, M.T.4
Kesari, P.5
-
22
-
-
0034799675
-
Sphingosine 1-phosphate promotes endothelial cell barrier integrity byEdg-dependent cytoskeletal rearrangement
-
Garcia JG, Liu F, Verin AD, Birukova A, Dechert MA, et al. 2001. Sphingosine 1-phosphate promotes endothelial cell barrier integrity byEdg-dependent cytoskeletal rearrangement. J. Clin. Investig. 108:689-701
-
(2001)
J. Clin. Investig
, vol.108
, pp. 689-701
-
-
Garcia, J.G.1
Liu, F.2
Verin, A.D.3
Birukova, A.4
Dechert, M.A.5
-
23
-
-
2642580994
-
Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: Roles for cortactin and myosin light chain kinase
-
Dudek SM, Jacobson JR, Chiang ET, Birukov KG, Wang P, et al. 2004. Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase. J. Biol. Chem. 279:24692-700
-
(2004)
J. Biol. Chem
, vol.279
, pp. 24692-24700
-
-
Dudek, S.M.1
Jacobson, J.R.2
Chiang, E.T.3
Birukov, K.G.4
Wang, P.5
-
24
-
-
0037370946
-
S1P induces FA remodeling in human pulmonary endothelial cells: Role of Rac, GIT1, FAK, and paxillin
-
Shikata Y, Birukov KG, Garcia JG. 2003. S1P induces FA remodeling in human pulmonary endothelial cells: role of Rac, GIT1, FAK, and paxillin. J. Appl. Physiol. 94:1193-203
-
(2003)
J. Appl. Physiol
, vol.94
, pp. 1193-1203
-
-
Shikata, Y.1
Birukov, K.G.2
Garcia, J.G.3
-
25
-
-
84863490207
-
IQGAP1 is necessary for pulmonary vascular barrier protection in murine acute lung injury and pneumonia
-
Bhattacharya M, Su G, Su X, Oses-Prieto JA, Li JT, et al. 2012. IQGAP1 is necessary for pulmonary vascular barrier protection in murine acute lung injury and pneumonia. Am. J. Physiol. Lung Cell. Mol. Physiol. 303:L12-19
-
(2012)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.303
, pp. L12-19
-
-
Bhattacharya, M.1
Su, G.2
Su, X.3
Oses-Prieto, J.A.4
Li, J.T.5
-
26
-
-
77952327561
-
Differential effects of sphingosine 1-phosphate receptors on airway and vascular barrier function in the murine lung
-
Sammani S, Moreno-Vinasco L, Mirzapoiazova T, Singleton PA, Chiang ET, et al. 2010. Differential effects of sphingosine 1-phosphate receptors on airway and vascular barrier function in the murine lung. Am. J. Respir. Cell Mol. Biol. 43:394-402
-
(2010)
Am. J. Respir. Cell Mol. Biol
, vol.43
, pp. 394-402
-
-
Sammani, S.1
Moreno-Vinasco, L.2
Mirzapoiazova, T.3
Singleton, P.A.4
Chiang, E.T.5
-
27
-
-
84868328440
-
Sphingosine-1-phosphate receptor-3 is a novel biomarker in acute lung injury
-
Sun X, Singleton PA, Letsiou E, Zhao J, Belvitch P, et al. 2012. Sphingosine-1-phosphate receptor-3 is a novel biomarker in acute lung injury. Am. J. Respir. Cell Mol. Biol. 47:628-36
-
(2012)
Am. J. Respir. Cell Mol. Biol
, vol.47
, pp. 628-636
-
-
Sun, X.1
Singleton, P.A.2
Letsiou, E.3
Zhao, J.4
Belvitch, P.5
-
28
-
-
84884967921
-
Functional promoter variants in sphingosine 1-phosphate receptor 3 associate with susceptibility to sepsis-associated acute respiratory distress syndrome
-
Sun X, Ma SF, Wade MS, Acosta-Herrera M, Villar J, et al. 2013. Functional promoter variants in sphingosine 1-phosphate receptor 3 associate with susceptibility to sepsis-associated acute respiratory distress syndrome. Am. J. Physiol. Lung Cell. Mol. Physiol. 305:L467-77
-
(2013)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.305
, pp. L467-L477
-
-
Sun, X.1
Ma, S.F.2
Wade, M.S.3
Acosta-Herrera, M.4
Villar, J.5
-
29
-
-
79955408396
-
Fingolimod (FTY720): A recently approved multiple sclerosis drug based on a fungal secondary metabolite
-
StraderCR, Pearce CJ,Oberlies NH. 2011. Fingolimod (FTY720): a recently approved multiple sclerosis drug based on a fungal secondary metabolite. J. Nat. Prod. 74:900-7
-
(2011)
J. Nat. Prod
, vol.74
, pp. 900-907
-
-
Strader, C.R.1
Pearce, C.J.2
Oberlies, N.H.3
-
30
-
-
3543011977
-
Synthesis of l-lyxo-phytosphingosine and its 1-phosphonate analogue using a threitol acetal synthon
-
Lu X, Byun HS, Bittman R. 2004. Synthesis of l-lyxo-phytosphingosine and its 1-phosphonate analogue using a threitol acetal synthon. J. Org. Chem. 69:5433-38
-
(2004)
J. Org. Chem
, vol.69
, pp. 5433-5438
-
-
Lu, X.1
Byun, H.S.2
Bittman, R.3
-
31
-
-
65249159253
-
Chiral vinylphosphonate and phosphonate analogues of the immunosuppressive agent FTY720
-
Lu X, Sun C, Valentine WJ, Shuyu E, Liu J, et al. 2009. Chiral vinylphosphonate and phosphonate analogues of the immunosuppressive agent FTY720. J. Org. Chem. 74:3192-95
-
(2009)
J. Org. Chem
, vol.74
, pp. 3192-3195
-
-
Lu, X.1
Sun, C.2
Valentine, W.J.3
Shuyu, E.4
Liu, J.5
-
32
-
-
70349327604
-
Synthetic analogs of FTY720 [2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol] differentially regulate pulmonary vascular permeability in vivo and in vitro
-
Camp SM, Bittman R, Chiang ET, Moreno-Vinasco L, Mirzapoiazova T, et al. 2009. Synthetic analogs of FTY720 [2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol] differentially regulate pulmonary vascular permeability in vivo and in vitro. J. Pharmacol. Exp. Ther. 331:54-64
-
(2009)
J. Pharmacol. Exp. Ther
, vol.331
, pp. 54-64
-
-
Camp, S.M.1
Bittman, R.2
Chiang, E.T.3
Moreno-Vinasco, L.4
Mirzapoiazova, T.5
-
33
-
-
84894483889
-
FTY720 (S)-phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury
-
Wang L, Sammani S, Moreno-Vinasco L, Letsiou E, Wang T, et al. 2014. FTY720 (S)-phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury. Crit. Care Med. 42:e189-99
-
(2014)
Crit. Care Med
, vol.42
, pp. e189-e199
-
-
Wang, L.1
Sammani, S.2
Moreno-Vinasco, L.3
Letsiou, E.4
Wang, T.5
-
34
-
-
80051658461
-
Protection of LPS-induced murine acute lung injury by sphingosine-1-phosphate lyase suppression
-
Zhao Y, Gorshkova IA, Berdyshev E, He D, Fu P, et al. 2011. Protection of LPS-induced murine acute lung injury by sphingosine-1-phosphate lyase suppression. Am. J. Respir. Cell Mol. Biol. 45:426-35
-
(2011)
Am. J. Respir. Cell Mol. Biol
, vol.45
, pp. 426-435
-
-
Zhao, Y.1
Gorshkova, I.A.2
Berdyshev, E.3
He, D.4
Fu, P.5
-
35
-
-
78650645373
-
Ceramide and ceramide 1-phosphate are negative regulators of TNF-αproduction induced by lipopolysaccharide
-
Jozefowski S, Czerkies M, Lukasik A, Bielawska A, Bielawski J, et al. 2010. Ceramide and ceramide 1-phosphate are negative regulators of TNF-αproduction induced by lipopolysaccharide. J. Immunol. 185:6960-73
-
(2010)
J. Immunol
, vol.185
, pp. 6960-6973
-
-
Jozefowski, S.1
Czerkies, M.2
Lukasik, A.3
Bielawska, A.4
Bielawski, J.5
-
36
-
-
84860649714
-
IKK NBD peptide inhibits LPS induced pulmonary inflammation and alters sphingolipid metabolism in a murine model
-
von Bismarck P,Winoto-Morbach S, Herzberg M, Uhlig U, Schutze S, et al. 2012. IKK NBD peptide inhibits LPS induced pulmonary inflammation and alters sphingolipid metabolism in a murine model. Pulm. Pharmacol. Ther. 25:228-35
-
(2012)
Pulm. Pharmacol. Ther
, vol.25
, pp. 228-235
-
-
Von Bismarck, P.1
Winoto-Morbach, S.2
Herzberg, M.3
Uhlig, U.4
Schutze, S.5
-
37
-
-
79551555431
-
Endotoxin activates de novo sphingolipid biosynthesis via nuclear factor kappa B-mediated upregulation of Sptlc2
-
Chang ZQ, Lee SY, Kim HJ, Kim JR, Kim SJ, et al. 2011. Endotoxin activates de novo sphingolipid biosynthesis via nuclear factor kappa B-mediated upregulation of Sptlc2. Prostaglandins Other Lipid Mediat. 94:44-52
-
(2011)
Prostaglandins Other Lipid Mediat
, vol.94
, pp. 44-52
-
-
Chang, Z.Q.1
Lee, S.Y.2
Kim, H.J.3
Kim, J.R.4
Kim, S.J.5
-
38
-
-
2942729796
-
Cooperative prosurvival activity by ERK and Akt in human alveolar macrophages is dependent on high levels of acid ceramidase activity
-
Monick MM, Mallampalli RK, Bradford M, McCoy D, Gross TJ, et al. 2004. Cooperative prosurvival activity by ERK and Akt in human alveolar macrophages is dependent on high levels of acid ceramidase activity. J. Immunol. 173:123-35
-
(2004)
J. Immunol
, vol.173
, pp. 123-135
-
-
Monick, M.M.1
Mallampalli, R.K.2
Bradford, M.3
McCoy, D.4
Gross, T.J.5
-
39
-
-
80053147547
-
Inhibition of neutrophil apoptosis via sphingolipid signaling in acute lung injury
-
LinWC, LinCF, Chen CL,ChenCW, Lin YS. 2011. Inhibition of neutrophil apoptosis via sphingolipid signaling in acute lung injury. J. Pharmacol. Exp. Ther. 339:45-53
-
(2011)
J. Pharmacol. Exp. Ther
, vol.339
, pp. 45-53
-
-
Lin, W.C.1
Lin, C.F.2
Chen, C.L.3
Chen, C.W.4
Lin, Y.S.5
-
40
-
-
84938204167
-
LPS-mediated septic shock is augmented in ceramide synthase 2 null mice due to elevated activity of TNFα-converting enzyme
-
AliM, Saroha A, Pewzner-Jung Y, Futerman AH. 2015. LPS-mediated septic shock is augmented in ceramide synthase 2 null mice due to elevated activity of TNFα-converting enzyme. FEBS Lett. 589:2213-17
-
(2015)
FEBS Lett
, vol.589
, pp. 2213-2217
-
-
Ali, M.1
Saroha, A.2
Pewzner-Jung, Y.3
Futerman, A.H.4
-
41
-
-
84942429418
-
Sphingosine 1-phosphate receptor 2 signaling suppresses macrophage phagocytosis and impairs host defense against sepsis
-
Hou J, Chen Q, Zhang K, Cheng B, Xie G, et al. 2015. Sphingosine 1-phosphate receptor 2 signaling suppresses macrophage phagocytosis and impairs host defense against sepsis. Anesthesiology 123:409-22
-
(2015)
Anesthesiology
, vol.123
, pp. 409-422
-
-
Hou, J.1
Chen, Q.2
Zhang, K.3
Cheng, B.4
Xie, G.5
-
42
-
-
84929341177
-
Ceramide-1-phosphate inhibits cigarette smoke-induced airway inflammation
-
Baudiss K, Ayata CK, Lazar Z, Cicko S, Beckert J, et al. 2015. Ceramide-1-phosphate inhibits cigarette smoke-induced airway inflammation. Eur. Respir. J. 45:1669-80
-
(2015)
Eur. Respir. J
, vol.45
, pp. 1669-1680
-
-
Baudiss, K.1
Ayata, C.K.2
Lazar, Z.3
Cicko, S.4
Beckert, J.5
-
43
-
-
30344435318
-
Ceramide-1-phosphate: The "missing" link in eicosanoid biosynthesis and inflammation
-
Lamour NF, Chalfant CE. 2005. Ceramide-1-phosphate: the "missing" link in eicosanoid biosynthesis and inflammation. Mol. Interv. 5:358-67
-
(2005)
Mol. Interv
, vol.5
, pp. 358-367
-
-
Lamour, N.F.1
Chalfant, C.E.2
-
44
-
-
84929378556
-
Sphingomyelinase D/ceramide 1-phosphate in cell survival and inflammation
-
Rivera IG, Ordonez M, PresaN,Gomez-Larrauri A, Simon J, et al. 2015. Sphingomyelinase D/ceramide 1-phosphate in cell survival and inflammation. Toxins 7:1457-66
-
(2015)
Toxins
, vol.7
, pp. 1457-1466
-
-
Rivera, I.G.1
Ordonez, M.2
Presa, N.3
Gomez-Larrauri, A.4
Simon, J.5
-
45
-
-
77649122069
-
Ceramide and ceramide 1-phosphate in health and disease
-
Arana L, Gangoiti P, Ouro A, TruebaM, Gomez-Munoz A. 2010. Ceramide and ceramide 1-phosphate in health and disease. Lipids Health Dis. 9:15
-
(2010)
Lipids Health Dis
, vol.9
, pp. 15
-
-
Arana, L.1
Gangoiti, P.2
Ouro, A.3
Trueba, M.4
Gomez-Munoz, A.5
-
46
-
-
66149185444
-
Ceramide-dependent PP2A regulation of TNFα-induced IL-8 production in respiratory epithelial cells
-
Cornell TT, Hinkovska-Galcheva V, Sun L, Cai Q, Hershenson MB, et al. 2009. Ceramide-dependent PP2A regulation of TNFα-induced IL-8 production in respiratory epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 296:L849-56
-
(2009)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.296
, pp. L849-L856
-
-
Cornell, T.T.1
Hinkovska-Galcheva, V.2
Sun, L.3
Cai, Q.4
Hershenson, M.B.5
-
47
-
-
0037214084
-
Alveolar sphingolipids generated in response to TNF-αmodifies surfactant biophysical activity
-
Ryan AJ, McCoy DM, McGowan SE, Salome RG, Mallampalli RK. 2003. Alveolar sphingolipids generated in response to TNF-αmodifies surfactant biophysical activity. J. Appl. Physiol. 1985 94:253-58
-
(2003)
J. Appl. Physiol
, vol.94
, pp. 253-258
-
-
Ryan, A.J.1
McCoy, D.M.2
McGowan, S.E.3
Salome, R.G.4
Mallampalli, R.K.5
-
48
-
-
44449165512
-
Improved pulmonary function by acid sphingomyelinase inhibition in a newborn piglet lavage model
-
von Bismarck P,Wistadt CF, Klemm K, Winoto-Morbach S, Uhlig U, et al. 2008. Improved pulmonary function by acid sphingomyelinase inhibition in a newborn piglet lavage model. Am. J. Respir. Crit. Care Med. 177:1233-41
-
(2008)
Am. J. Respir. Crit. Care Med
, vol.177
, pp. 1233-1241
-
-
Von Bismarck, P.1
Wistadt, C.F.2
Klemm, K.3
Winoto-Morbach, S.4
Uhlig, U.5
-
49
-
-
84961289697
-
CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction
-
Tabeling C, Yu H,Wang L, Ranke H, Goldenberg NM, et al. 2015. CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction. PNAS 112:E1614-23
-
(2015)
PNAS
, vol.112
, pp. E1614-E1623
-
-
Tabeling, C.1
Yu, H.2
Wang, L.3
Ranke, H.4
Goldenberg, N.M.5
-
50
-
-
2542431022
-
Sphingosine 1-phosphate induces antimicrobial activity both in vitro and in vivo
-
Garg SK, Volpe E, Palmieri G, Mattei M, Galati D, et al. 2004. Sphingosine 1-phosphate induces antimicrobial activity both in vitro and in vivo. J. Infect. Dis. 189:2129-38
-
(2004)
J. Infect. Dis
, vol.189
, pp. 2129-2138
-
-
Garg, S.K.1
Volpe, E.2
Palmieri, G.3
Mattei, M.4
Galati, D.5
-
51
-
-
84916929004
-
Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa
-
Pewzner-Jung Y, Tavakoli Tabazavareh S, Grassme H, Becker KA, Japtok L, et al. 2014. Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa. EMBO Mol. Med. 6:1205-14
-
(2014)
EMBO Mol. Med
, vol.6
, pp. 1205-1214
-
-
Pewzner-Jung, Y.1
Tavakoli, T.S.2
Grassme, H.3
Becker, K.A.4
Japtok, L.5
-
52
-
-
0025738161
-
Galactosyl ceramide or a derivative is an essential component of the neural receptor for human immunodeficiency virus type 1 envelope glycoprotein gp120
-
Bhat S, Spitalnik SL, Gonzalez-Scarano F, Silberberg DH. 1991. Galactosyl ceramide or a derivative is an essential component of the neural receptor for human immunodeficiency virus type 1 envelope glycoprotein gp120. PNAS 88:7131-34
-
(1991)
PNAS
, vol.88
, pp. 7131-7134
-
-
Bhat, S.1
Spitalnik, S.L.2
Gonzalez-Scarano, F.3
Silberberg, D.H.4
-
53
-
-
7444248910
-
Ceramide, a target for antiretroviral therapy
-
Finnegan CM, Rawat SS, Puri A, Wang JM, Ruscetti FW, Blumenthal R. 2004. Ceramide, a target for antiretroviral therapy. PNAS 101:15452-57
-
(2004)
PNAS
, vol.101
, pp. 15452-15457
-
-
Finnegan, C.M.1
Rawat, S.S.2
Puri, A.3
Wang, J.M.4
Ruscetti, F.W.5
Blumenthal, R.6
-
54
-
-
2942521188
-
Sphingosine kinase mediates activation of extracellular signal-related kinase and Akt by respiratory syncytial virus
-
Monick MM, Cameron K, Powers LS, Butler NS, McCoy D, et al. 2004. Sphingosine kinase mediates activation of extracellular signal-related kinase and Akt by respiratory syncytial virus. Am. J. Respir. Cell Mol. Biol. 30:844-52
-
(2004)
Am. J. Respir. Cell Mol. Biol
, vol.30
, pp. 844-852
-
-
Monick, M.M.1
Cameron, K.2
Powers, L.S.3
Butler, N.S.4
McCoy, D.5
-
55
-
-
84928485431
-
A ceramide analogue stimulates dendritic cells to promote T cell responses upon virus infections
-
Pritzl CJ, Seo YJ, XiaC, Vijayan M, Stokes ZD, Hahm B. 2015. A ceramide analogue stimulates dendritic cells to promote T cell responses upon virus infections. J. Immunol. 194:4339-49
-
(2015)
J. Immunol
, vol.194
, pp. 4339-4349
-
-
Pritzl, C.J.1
Seo, Y.J.2
Xia, C.3
Vijayan, M.4
Stokes, Z.D.5
Hahm, B.6
-
56
-
-
0034746796
-
Activation of Vα14+ natural killer T cells by α-galactosylceramide results in development of Th1 response and local host resistance in mice infected with Cryptococcus neoformans
-
Kawakami K, Kinjo Y, Yara S, Koguchi Y, Uezu K, et al. 2001. Activation of Vα14+ natural killer T cells by α-galactosylceramide results in development of Th1 response and local host resistance in mice infected with Cryptococcus neoformans. Infect. Immun. 69:213-20
-
(2001)
Infect. Immun
, vol.69
, pp. 213-220
-
-
Kawakami, K.1
Kinjo, Y.2
Yara, S.3
Koguchi, Y.4
Uezu, K.5
-
57
-
-
84864776533
-
Pathogenesis of chronic obstructive pulmonary disease
-
Tuder RM, Petrache I. 2012. Pathogenesis of chronic obstructive pulmonary disease. J. Clin. Investig. 122:2749-55
-
(2012)
J. Clin. Investig
, vol.122
, pp. 2749-2755
-
-
Tuder, R.M.1
Petrache, I.2
-
58
-
-
84880540714
-
The involvement of sphingolipids in chronic obstructive pulmonary diseases
-
Petrache I, Petrusca DN. 2013. The involvement of sphingolipids in chronic obstructive pulmonary diseases. Handb. Exp. Pharmacol. 2013:247-64
-
(2013)
Handb. Exp. Pharmacol
, vol.2013
, pp. 247-264
-
-
Petrache, I.1
Petrusca, D.N.2
-
59
-
-
18844434417
-
Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice
-
Petrache I, Natarajan V, Zhen L, Medler TR, Richter AT, et al. 2005. Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nat. Med. 11:491-98
-
(2005)
Nat. Med
, vol.11
, pp. 491-498
-
-
Petrache, I.1
Natarajan, V.2
Zhen, L.3
Medler, T.R.4
Richter, A.T.5
-
60
-
-
78650057959
-
Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages
-
Petrusca DN, Gu Y, Adamowicz JJ, Rush NI, Hubbard WC, et al. 2010. Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages. J. Biol. Chem. 285:40322-32
-
(2010)
J. Biol. Chem
, vol.285
, pp. 40322-40332
-
-
Petrusca, D.N.1
Gu, Y.2
Adamowicz, J.J.3
Rush, N.I.4
Hubbard, W.C.5
-
61
-
-
84871061105
-
Modulation of macrophage efferocytosis in inflammation
-
Korns D, Frasch SC, Fernandez-Boyanapalli R, Henson PM, Bratton DL. 2011. Modulation of macrophage efferocytosis in inflammation. Front. Immunol. 2:57
-
(2011)
Front. Immunol
, vol.2
, pp. 57
-
-
Korns, D.1
Frasch, S.C.2
Fernandez-Boyanapalli, R.3
Henson, P.M.4
Bratton, D.L.5
-
62
-
-
84939995951
-
Lactosylceramide-accumulation in lipid-rafts mediate aberrant-autophagy, inflammation and apoptosis in cigarette smoke induced emphysema
-
BodasM,Min T, Vij N. 2015. Lactosylceramide-accumulation in lipid-rafts mediate aberrant-autophagy, inflammation and apoptosis in cigarette smoke induced emphysema. Apoptosis 20:725-39
-
(2015)
Apoptosis
, vol.20
, pp. 725-739
-
-
Bodas, M.1
Min, T.2
Vij, N.3
-
63
-
-
76149139431
-
Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema
-
Diab KJ, Adamowicz JJ, Kamocki K, Rush NI, Garrison J, et al. 2010. Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema. Am. J. Respir. Crit. Care Med. 181:344-52
-
(2010)
Am. J. Respir. Crit. Care Med
, vol.181
, pp. 344-352
-
-
Diab, K.J.1
Adamowicz, J.J.2
Kamocki, K.3
Rush, N.I.4
Garrison, J.5
-
64
-
-
84923888561
-
Space radiation associated lung injury in a murine model
-
Christofidou-Solomidou M, Pietrofesa RA, Arguiri E, Schweitzer KS, Berdyshev EV, et al. 2015. Space radiation associated lung injury in a murine model. Am. J. Physiol. Lung Cell. Mol. Physiol. 308:L416-28
-
(2015)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.308
, pp. L416-L428
-
-
Christofidou-Solomidou, M.1
Pietrofesa, R.A.2
Arguiri, E.3
Schweitzer, K.S.4
Berdyshev, E.V.5
-
65
-
-
84922308684
-
Plasma sphingolipids associated with chronic obstructive pulmonary disease phenotypes
-
Bowler RP, Jacobson S, Cruickshank C,Hughes GJ, Siska C, et al. 2015. Plasma sphingolipids associated with chronic obstructive pulmonary disease phenotypes. Am. J. Respir. Crit. Care Med. 191:275-84
-
(2015)
Am. J. Respir. Crit. Care Med
, vol.191
, pp. 275-284
-
-
Bowler, R.P.1
Jacobson, S.2
Cruickshank, C.3
Hughes, G.J.4
Siska, C.5
-
66
-
-
84904045084
-
Transient and persistent metabolomic changes in plasma following chronic cigarette smoke exposure in a mousemodel
-
Cruickshank-Quinn CI, Mahaffey S, Justice MJ, Hughes G, Armstrong M, et al. 2014. Transient and persistent metabolomic changes in plasma following chronic cigarette smoke exposure in a mousemodel. PLOS ONE 9:e101855
-
(2014)
PLOS ONE
, vol.9
, pp. e101855
-
-
Cruickshank-Quinn, C.I.1
Mahaffey, S.2
Justice, M.J.3
Hughes, G.4
Armstrong, M.5
-
67
-
-
49049112707
-
Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide
-
Petrache I, Medler TR, Richter AT, Kamocki K, Chukwueke U, et al. 2008. Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide. Am. J. Physiol. Lung Cell. Mol. Physiol. 295:L44-53
-
(2008)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.295
, pp. L44-53
-
-
Petrache, I.1
Medler, T.R.2
Richter, A.T.3
Kamocki, K.4
Chukwueke, U.5
-
70
-
-
80052625342
-
Lipids in cystic fibrosis
-
Becker KA, Henry B, Ziobro R, Riethmuller J, Gulbins E. 2011. Lipids in cystic fibrosis. Expert Rev. Respir. Med. 5:527-35
-
(2011)
Expert Rev. Respir. Med
, vol.5
, pp. 527-535
-
-
Becker, K.A.1
Henry, B.2
Ziobro, R.3
Riethmuller, J.4
Gulbins, E.5
-
71
-
-
41849092177
-
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis
-
Teichgraber V, Ulrich M, Endlich N, Riethmuller J, Wilker B, et al. 2008. Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat. Med. 14:382-91
-
(2008)
Nat. Med
, vol.14
, pp. 382-391
-
-
Teichgraber, V.1
Ulrich, M.2
Endlich, N.3
Riethmuller, J.4
Wilker, B.5
-
73
-
-
0035929556
-
Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: Modulation of cellular activity of sphingosine 1-phosphate
-
Boujaoude LC, Bradshaw-Wilder C, Mao C, Cohn J, Ogretmen B, et al. 2001. Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate. J. Biol. Chem. 276:35258-64
-
(2001)
J. Biol. Chem
, vol.276
, pp. 35258-35264
-
-
Boujaoude, L.C.1
Bradshaw-Wilder, C.2
Mao, C.3
Cohn, J.4
Ogretmen, B.5
-
74
-
-
67049121806
-
Defective CFTR increases synthesis and mass of sphingolipids that modulate membrane composition and lipid signaling
-
Hamai H, Keyserman F, Quittell LM,Worgall TS. 2009. Defective CFTR increases synthesis and mass of sphingolipids that modulate membrane composition and lipid signaling. J. Lipid Res. 50:1101-8
-
(2009)
J. Lipid Res
, vol.50
, pp. 1101-1108
-
-
Hamai, H.1
Keyserman, F.2
Quittell, L.M.3
Worgall, T.S.4
-
75
-
-
67249161586
-
CFTR regulation of intracellular pH and ceramides is required for lung endothelial cell apoptosis
-
Noe J, Petrusca D, Rush N, Deng P, VanDemark M, et al. 2009. CFTR regulation of intracellular pH and ceramides is required for lung endothelial cell apoptosis. Am. J. Respir. Cell Mol. Biol. 41:314-23
-
(2009)
Am. J. Respir. Cell Mol. Biol
, vol.41
, pp. 314-323
-
-
Noe, J.1
Petrusca, D.2
Rush, N.3
Deng, P.4
VanDemark, M.5
-
76
-
-
33646540731
-
Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers
-
CantinAM, Hanrahan JW, Bilodeau G, Ellis L, DupuisA, et al. 2006. Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers.Am. J. Respir. Crit.CareMed. 173:1139-44
-
(2006)
Am. J. Respir. Crit. CareMed
, vol.173
, pp. 1139-1144
-
-
Cantin, A.M.1
Hanrahan, J.W.2
Bilodeau, G.3
Ellis, L.4
Dupuis, A.5
-
77
-
-
84856557879
-
Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration
-
Clunes LA, Davies CM, Coakley RD, Aleksandrov AA, Henderson AG, et al. 2012. Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration. FASEB J. 26:533-45
-
(2012)
FASEB J
, vol.26
, pp. 533-545
-
-
Clunes, L.A.1
Davies, C.M.2
Coakley, R.D.3
Aleksandrov, A.A.4
Henderson, A.G.5
-
78
-
-
34547216747
-
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
-
Moffatt MF, Kabesch M, Liang L, Dixon AL, Strachan D, et al. 2007. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448:470-73
-
(2007)
Nature
, vol.448
, pp. 470-473
-
-
Moffatt, M.F.1
Kabesch, M.2
Liang, L.3
Dixon, A.L.4
Strachan, D.5
-
79
-
-
77957113600
-
A large-scale, consortium-based genomewide association study of asthma
-
MoffattMF, Gut IG, Demenais F, Strachan DP, Bouzigon E, et al. 2010. A large-scale, consortium-based genomewide association study of asthma. N. Engl. J. Med. 363:1211-21
-
(2010)
N. Engl. J. Med
, vol.363
, pp. 1211-1221
-
-
Moffatt, M.F.1
Gut, I.G.2
Demenais, F.3
Strachan, D.P.4
Bouzigon, E.5
-
80
-
-
84914144572
-
A genome-wide survey of CD4+ lymphocyte regulatory genetic variants identifies novel asthma genes
-
Sharma S, Zhou X, Thibault DM, Himes BE, Liu A, et al. 2014. A genome-wide survey of CD4+ lymphocyte regulatory genetic variants identifies novel asthma genes. J. Allergy Clin. Immunol. 134:1153-62
-
(2014)
J. Allergy Clin. Immunol
, vol.134
, pp. 1153-1162
-
-
Sharma, S.1
Zhou, X.2
Thibault, D.M.3
Himes, B.E.4
Liu, A.5
-
81
-
-
84940086097
-
Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice
-
Oyeniran C, Sturgill JL, Hait NC, Huang WC, Avni D, et al. 2015. Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice. J. Allergy Clin. Immunol. 136:1035-46.e6
-
(2015)
J. Allergy Clin. Immunol
, vol.136
, pp. 1035e6-1046e6
-
-
Oyeniran, C.1
Sturgill, J.L.2
Hait, N.C.3
Huang, W.C.4
Avni, D.5
-
82
-
-
84927534633
-
ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis
-
Siow D, Sunkara M, Dunn TM, Morris AJ, Wattenberg B. 2015. ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis. J. Lipid Res. 56:898-908
-
(2015)
J. Lipid Res
, vol.56
, pp. 898-908
-
-
Siow, D.1
Sunkara, M.2
Dunn, T.M.3
Morris, A.J.4
Wattenberg, B.5
-
84
-
-
84907906360
-
Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells
-
Fuerst E, Foster HR, Ward JP, Corrigan CJ, Cousins DJ, Woszczek G. 2014. Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells. Allergy 69:1531-39
-
(2014)
Allergy
, vol.69
, pp. 1531-1539
-
-
Fuerst, E.1
Foster, H.R.2
Ward, J.P.3
Corrigan, C.J.4
Cousins, D.J.5
Woszczek, G.6
-
85
-
-
84873409675
-
A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell-dependent murine model of allergic asthma
-
Price MM, Oskeritzian CA, Falanga YT,Harikumar KB, Allegood JC, et al. 2013. A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell-dependent murine model of allergic asthma. J. Allergy Clin. Immunol. 131:501-11.e1
-
(2013)
J. Allergy Clin. Immunol
, vol.131
, pp. 501e1-511e1
-
-
Price, M.M.1
Oskeritzian, C.A.2
Falanga, Y.T.3
Harikumar, K.B.4
Allegood, J.C.5
-
86
-
-
84864119788
-
Sphingosine-1-phosphate-induced airway hyper-reactivity in rodents is mediated by the sphingosine-1-phosphate type 3 receptor
-
Trifilieff A, Fozard JR. 2012. Sphingosine-1-phosphate-induced airway hyper-reactivity in rodents is mediated by the sphingosine-1-phosphate type 3 receptor. J. Pharmacol. Exp. Ther. 342:399-406
-
(2012)
J. Pharmacol. Exp. Ther
, vol.342
, pp. 399-406
-
-
Trifilieff, A.1
Fozard, J.R.2
-
87
-
-
84859755615
-
Treatment with a sphingosine-1-phosphate analog inhibits airway remodeling following repeated allergen exposure
-
Karmouty-Quintana H, Siddiqui S, Hassan M, Tsuchiya K, Risse PA, et al. 2012. Treatment with a sphingosine-1-phosphate analog inhibits airway remodeling following repeated allergen exposure. Am. J. Physiol. Lung Cell. Mol. Physiol. 302:L736-45
-
(2012)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.302
, pp. L736-L745
-
-
Karmouty-Quintana, H.1
Siddiqui, S.2
Hassan, M.3
Tsuchiya, K.4
Risse, P.A.5
-
88
-
-
78649403525
-
SKI-II, an inhibitor of sphingosine kinase, ameliorates antigen-induced bronchial smooth muscle hyperresponsiveness, but not airway inflammation, in mice
-
Chiba Y, Takeuchi H, Sakai H, Misawa M. 2010. SKI-II, an inhibitor of sphingosine kinase, ameliorates antigen-induced bronchial smooth muscle hyperresponsiveness, but not airway inflammation, in mice. J. Pharmacol. Sci. 114:304-10
-
(2010)
J. Pharmacol. Sci
, vol.114
, pp. 304-310
-
-
Chiba, Y.1
Takeuchi, H.2
Sakai, H.3
Misawa, M.4
-
89
-
-
77951638132
-
Systemic administration of sphingosine-1-phosphate increases bronchial hyperresponsiveness in the mouse
-
Roviezzo F, D'Agostino B, Brancaleone V, De Gruttola L, Bucci M, et al. 2010. Systemic administration of sphingosine-1-phosphate increases bronchial hyperresponsiveness in the mouse. Am. J. Respir. Cell Mol. Biol. 42:572-77
-
(2010)
Am. J. Respir. Cell Mol. Biol
, vol.42
, pp. 572-577
-
-
Roviezzo, F.1
D'Agostino, B.2
Brancaleone, V.3
De Gruttola, L.4
Bucci, M.5
-
90
-
-
34249898946
-
Sphingosine-1-phosphate/sphingosine kinase pathway is involved in mouse airway hyperresponsiveness
-
Roviezzo F, Di Lorenzo A, Bucci M, Brancaleone V, Vellecco V, et al. 2007. Sphingosine-1-phosphate/sphingosine kinase pathway is involved in mouse airway hyperresponsiveness. Am. J. Respir. Cell Mol. Biol. 36:757-62
-
(2007)
Am. J. Respir. Cell Mol. Biol
, vol.36
, pp. 757-762
-
-
Roviezzo, F.1
Di Lorenzo, A.2
Bucci, M.3
Brancaleone, V.4
Vellecco, V.5
-
91
-
-
0035348292
-
Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma
-
Ammit AJ, Hastie AT, Edsall LC, Hoffman RK, Amrani Y, et al. 2001. Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma. FASEB J. 15:1212-14
-
(2001)
FASEB J
, vol.15
, pp. 1212-1214
-
-
Ammit, A.J.1
Hastie, A.T.2
Edsall, L.C.3
Hoffman, R.K.4
Amrani, Y.5
-
92
-
-
0141780843
-
Sphingosine-1-phosphate stimulates contraction of human airway smooth muscle cells
-
Rosenfeldt HM, Amrani Y,Watterson KR,Murthy KS, Panettieri RA Jr, Spiegel S. 2003. Sphingosine-1-phosphate stimulates contraction of human airway smooth muscle cells. FASEB J. 17:1789-99
-
(2003)
FASEB J
, vol.17
, pp. 1789-1799
-
-
Rosenfeldt, H.M.1
Amrani, Y.2
Watterson, K.R.3
Murthy, K.S.4
Panettieri, R.A.5
Spiegel, S.6
-
93
-
-
84926245199
-
The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell-dependent acute allergic responses
-
Oskeritzian CA, Hait NC,Wedman P, Chumanevich A, Kolawole EM, et al. 2015. The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell-dependent acute allergic responses. J. Allergy Clin. Immunol. 135:1008-18.e1
-
(2015)
J. Allergy Clin. Immunol
, vol.135
, pp. 1008e1-1018e1
-
-
Oskeritzian, C.A.1
Hait, N.C.2
Wedman, P.3
Chumanevich, A.4
Kolawole, E.M.5
-
94
-
-
84875702933
-
Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis
-
Huang LS, Berdyshev E, Mathew B, Fu P, Gorshkova IA, et al. 2013. Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis. FASEB J. 27:1749-60
-
(2013)
FASEB J
, vol.27
, pp. 1749-1760
-
-
Huang, L.S.1
Berdyshev, E.2
Mathew, B.3
Fu, P.4
Gorshkova, I.A.5
-
95
-
-
84856066049
-
Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition
-
Milara J, Navarro R, Juan G, Peiro T, Serrano A, et al. 2012. Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition. Thorax 67:147-56
-
(2012)
Thorax
, vol.67
, pp. 147-156
-
-
Milara, J.1
Navarro, R.2
Juan, G.3
Peiro, T.4
Serrano, A.5
-
96
-
-
84920808580
-
Sphingolipids in pulmonary fibrosis
-
Huang LS, Natarajan V. 2015. Sphingolipids in pulmonary fibrosis. Adv. Biol. Regul. 57:55-63
-
(2015)
Adv. Biol. Regul
, vol.57
, pp. 55-63
-
-
Huang, L.S.1
Natarajan, V.2
-
97
-
-
84908691500
-
Knock out of S1P3 receptor signaling attenuates inflammation and fibrosis in bleomycin-induced lung injury mice model
-
Murakami K, Kohno M, Kadoya M, Nagahara H, Fujii W, et al. 2014. Knock out of S1P3 receptor signaling attenuates inflammation and fibrosis in bleomycin-induced lung injury mice model. PLOS ONE 9:e106792
-
(2014)
PLOS ONE
, vol.9
, pp. e106792
-
-
Murakami, K.1
Kohno, M.2
Kadoya, M.3
Nagahara, H.4
Fujii, W.5
-
98
-
-
84878240485
-
Sphingosine 1-phosphate (S1P) receptor agonists mediate pro-fibrotic responses in normal human lung fibroblasts via S1P2 and S1P3 receptors and Smad-independent signaling
-
Sobel K,Menyhart K, KillerN, Renault B, Bauer Y, et al. 2013. Sphingosine 1-phosphate (S1P) receptor agonists mediate pro-fibrotic responses in normal human lung fibroblasts via S1P2 and S1P3 receptors and Smad-independent signaling. J. Biol. Chem. 288:14839-51
-
(2013)
J. Biol. Chem
, vol.288
, pp. 14839-14851
-
-
Sobel, K.1
Menyhart, K.2
Killer, N.3
Renault, B.4
Bauer, Y.5
-
99
-
-
84863790153
-
Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression
-
Gorshkova I, Zhou T,Mathew B, Jacobson JR, Takekoshi D, et al. 2012. Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression. J. Lipid Res. 53:1553-68
-
(2012)
J. Lipid Res
, vol.53
, pp. 1553-1568
-
-
Gorshkova, I.1
Zhou, T.2
Mathew, B.3
Jacobson, J.R.4
Takekoshi, D.5
-
100
-
-
80053928581
-
Role of sphingolipids in murine radiation-induced lung injury: Protection by sphingosine 1-phosphate analogs
-
Mathew B, Jacobson JR, Berdyshev E, Huang Y, Sun X, et al. 2011. Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs. FASEB J. 25:3388-400
-
(2011)
FASEB J
, vol.25
, pp. 3388-3400
-
-
Mathew, B.1
Jacobson, J.R.2
Berdyshev, E.3
Huang, Y.4
Sun, X.5
-
101
-
-
0014075066
-
Gaucher's disease of the lung causing severe pulmonary hypertension with associated acute recurrent pericarditis
-
RobertsWC, Fredrickson DS. 1967. Gaucher's disease of the lung causing severe pulmonary hypertension with associated acute recurrent pericarditis. Circulation 35:783-89
-
(1967)
Circulation
, vol.35
, pp. 783-789
-
-
Roberts, W.C.1
Fredrickson, D.S.2
-
102
-
-
84895543498
-
Smoking exposure induces human lung endothelial cell adaptation to apoptotic stress
-
Petrusca DN, Van Demark M, Gu Y, Justice MJ, Rogozea A, et al. 2014. Smoking exposure induces human lung endothelial cell adaptation to apoptotic stress. Am. J. Respir. Cell Mol. Biol. 50:513-25
-
(2014)
Am. J. Respir. Cell Mol. Biol
, vol.50
, pp. 513-525
-
-
Petrusca, D.N.1
Van Demark, M.2
Gu, Y.3
Justice, M.J.4
Rogozea, A.5
-
103
-
-
84961290159
-
The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension
-
Chen J, Tang H, Sysol JR, Moreno-Vinasco L, Shioura KM, et al. 2014. The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension. Am. J. Respir. Crit. Care Med. 190:1032-43
-
(2014)
Am. J. Respir. Crit. Care Med
, vol.190
, pp. 1032-1043
-
-
Chen, J.1
Tang, H.2
Sysol, J.R.3
Moreno-Vinasco, L.4
Shioura, K.M.5
-
104
-
-
26944481591
-
Effects of exogenous sphinganine, sphingosine, and sphingosine-1-phosphate on relaxation and contraction of porcine thoracic aortic and pulmonary arterial rings
-
Hsiao SH, Constable PD, Smith GW, Haschek WM. 2005. Effects of exogenous sphinganine, sphingosine, and sphingosine-1-phosphate on relaxation and contraction of porcine thoracic aortic and pulmonary arterial rings. Toxicol. Sci. 86:194-99
-
(2005)
Toxicol. Sci
, vol.86
, pp. 194-199
-
-
Hsiao, S.H.1
Constable, P.D.2
Smith, G.W.3
Haschek, W.M.4
-
105
-
-
85016365810
-
S1P4 receptor mediates S1P-induced vasoconstriction in normotensive and hypertensive rat lungs
-
Ota H, Beutz MA, Ito M, Abe K, Oka M, McMurtry IF. 2011. S1P4 receptor mediates S1P-induced vasoconstriction in normotensive and hypertensive rat lungs. Pulm. Circ. 1:399-404
-
(2011)
Pulm. Circ
, vol.1
, pp. 399-404
-
-
Ota, H.1
Beutz, M.A.2
Ito, M.3
Abe, K.4
Oka, M.5
McMurtry, I.F.6
-
106
-
-
71749101249
-
Role of sphingosine kinase 1 in allergen-induced pulmonary vascular remodeling and hyperresponsiveness
-
Haberberger RV, Tabeling C, Runciman S, Gutbier B, Konig P, et al. 2009. Role of sphingosine kinase 1 in allergen-induced pulmonary vascular remodeling and hyperresponsiveness. J. Allergy Clin. Immunol. 124:933-41.e1-9
-
(2009)
J. Allergy Clin. Immunol
, vol.124
, pp. 933-41e19
-
-
Haberberger, R.V.1
Tabeling, C.2
Runciman, S.3
Gutbier, B.4
Konig, P.5
-
107
-
-
0035816611
-
Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells
-
Ogretmen B, Schady D, Usta J, Wood R, Kraveka JM, et al. 2001. Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells. J. Biol. Chem. 276:24901-10
-
(2001)
J. Biol. Chem
, vol.276
, pp. 24901-24910
-
-
Ogretmen, B.1
Schady, D.2
Usta, J.3
Wood, R.4
Kraveka, J.M.5
-
108
-
-
0037066727
-
De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells: Dependence on protein phosphatase-1
-
ChalfantCE, RathmanK, Pinkerman RL,Wood RE,Obeid LM, et al. 2002. De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells: dependence on protein phosphatase-1. J. Biol. Chem. 277:12587-95
-
(2002)
J. Biol. Chem
, vol.277
, pp. 12587-12595
-
-
Chalfant, C.E.1
Rathman, K.2
Pinkerman, R.L.3
Wood, R.E.4
Obeid, L.M.5
-
109
-
-
84882279153
-
Plasma sphingolipids and lung cancer: A population-based, nested case-control study
-
Alberg AJ, Armeson K, Pierce JS, Bielawski J, Bielawska A, et al. 2013. Plasma sphingolipids and lung cancer: a population-based, nested case-control study. Cancer Epidemiol. Biomark. Prev. 22:1374-82
-
(2013)
Cancer Epidemiol. Biomark. Prev
, vol.22
, pp. 1374-1382
-
-
Alberg, A.J.1
Armeson, K.2
Pierce, J.S.3
Bielawski, J.4
Bielawska, A.5
-
110
-
-
84914141686
-
Untargeted mass spectrometry-based metabolomic profiling of pleural effusions: Fatty acids as novel cancer biomarkers for malignant pleural effusions
-
Lam CW, Law CY. 2014. Untargeted mass spectrometry-based metabolomic profiling of pleural effusions: fatty acids as novel cancer biomarkers for malignant pleural effusions. J. Proteome Res. 13:4040-46
-
(2014)
J. Proteome Res
, vol.13
, pp. 4040-4046
-
-
Lam, C.W.1
Law, C.Y.2
-
111
-
-
0035920114
-
Suppression of integrin expression and tumorigenicity by sulfation of lactosylceramide in 3LL Lewis lung carcinoma cells
-
Kabayama K, Ito N, Honke K, Igarashi Y, Inokuchi J. 2001. Suppression of integrin expression and tumorigenicity by sulfation of lactosylceramide in 3LL Lewis lung carcinoma cells. J. Biol. Chem. 276:26777-83
-
(2001)
J. Biol. Chem
, vol.276
, pp. 26777-26783
-
-
Kabayama, K.1
Ito, N.2
Honke, K.3
Igarashi, Y.4
Inokuchi, J.5
-
112
-
-
84943427984
-
Targeting glucosylceramide synthase induction of cell surface globotriaosylceramide (Gb3) in acquired cisplatin-resistance of lung cancer and malignant pleural mesothelioma cells
-
Tyler A, Johansson A, Karlsson T, Gudey SK, Brannstrom T, et al. 2015. Targeting glucosylceramide synthase induction of cell surface globotriaosylceramide (Gb3) in acquired cisplatin-resistance of lung cancer and malignant pleural mesothelioma cells. Exp. Cell Res. 336:23-32
-
(2015)
Exp. Cell Res
, vol.336
, pp. 23-32
-
-
Tyler, A.1
Johansson, A.2
Karlsson, T.3
Gudey, S.K.4
Brannstrom, T.5
-
113
-
-
84930572472
-
Dietary glucosylceramides suppress tumor growth in a mouse xenograft model of head and neck squamous cell carcinoma by the inhibition of angiogenesis through an increase in ceramide
-
Yazama H, Kitatani K, Fujiwara K, Kato M, Hashimoto-Nishimura M, et al. 2015. Dietary glucosylceramides suppress tumor growth in a mouse xenograft model of head and neck squamous cell carcinoma by the inhibition of angiogenesis through an increase in ceramide. Int. J. Clin. Oncol. 20:438-46
-
(2015)
Int. J. Clin. Oncol
, vol.20
, pp. 438-446
-
-
Yazama, H.1
Kitatani, K.2
Fujiwara, K.3
Kato, M.4
Hashimoto-Nishimura, M.5
-
114
-
-
84884742613
-
Ceramides: A potential therapeutic target in pulmonary emphysema
-
Tibboel J, Reiss I, de Jongste JC, Post M. 2013. Ceramides: a potential therapeutic target in pulmonary emphysema. Respir. Res. 14:96
-
(2013)
Respir. Res
, vol.14
, pp. 96
-
-
Tibboel, J.1
Reiss, I.2
De Jongste, J.C.3
Post, M.4
|