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Volumn 27, Issue 4, 2013, Pages 1749-1760

Targeting sphingosine kinase 1 attenuates bleomycininduced pulmonary fibrosis

Author keywords

S1P; S1P lyase; TGF

Indexed keywords

BLEOMYCIN; PHOSPHOTRANSFERASE INHIBITOR; SMAD2 PROTEIN; SPHINGOSINE KINASE 1; TRANSFORMING GROWTH FACTOR BETA;

EID: 84875702933     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-219634     Document Type: Article
Times cited : (88)

References (45)
  • 1
    • 15444342697 scopus 로고    scopus 로고
    • Update in pulmonary medicine
    • King, T. E., Jr. (1998) Update in pulmonary medicine. Ann. Intern. Med. 129, 806-812.
    • (1998) Ann. Intern. Med. , vol.129 , pp. 806-812
    • King Jr., T.E.1
  • 2
    • 0025050820 scopus 로고
    • Differentiation repertoire of fibroblastic cells: Expression of cytoskeletal protein as marker of phenotypic modulations
    • Sappino, S.P., Schurch, W., and Gabbiani, G. (1990) Differentiation repertoire of fibroblastic cells: expression of cytoskeletal protein as marker of phenotypic modulations. Lab. Invest. 63, 144-161.
    • (1990) Lab. Invest. , vol.63 , pp. 144-161
    • Sappino, S.P.1    Schurch, W.2    Gabbiani, G.3
  • 3
    • 0036933489 scopus 로고    scopus 로고
    • The myofibroblast in pulmonary fibrosis
    • Phan, S. H. (2002) The myofibroblast in pulmonary fibrosis. Chest 122, 286S-289S.
    • (2002) Chest , vol.122
    • Phan, S.H.1
  • 4
    • 27644456575 scopus 로고    scopus 로고
    • NAD(P)H oxidase 4 mediates transforming growth factor b1-induced differentiation of cardiac fibroblasts into myofibroblasts
    • Cucoranu, I., Clempus, R., Dikalova, A., Phelan, P. J., Ariyan, S., Dikalov, S., and Sorescu, D. (2005) NAD(P)H oxidase 4 mediates transforming growth factor b1-induced differentiation of cardiac fibroblasts into myofibroblasts. Circ. Res. 97, 900-907.
    • (2005) Circ. Res. , vol.97 , pp. 900-907
    • Cucoranu, I.1    Clempus, R.2    Dikalova, A.3    Phelan, P.J.4    Ariyan, S.5    Dikalov, S.6    Sorescu, D.7
  • 5
    • 0035895243 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Prevailing and evolving hypotheses about its pathogenesis and implications for therapy
    • Selman, M., King, T. E., and Pardo, A. (2001) Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann. Intern. Med. 134, 136-151.
    • (2001) Ann. Intern. Med. , vol.134 , pp. 136-151
    • Selman, M.1    King, T.E.2    Pardo, A.3
  • 6
    • 80051718091 scopus 로고    scopus 로고
    • Modeling pulmonary fibrosis with bleomycin
    • Mouratis, M. A. and Aidinis, V. (2011) Modeling pulmonary fibrosis with bleomycin. Curr. Opin. Pulm. Med. 17, 355-361.
    • (2011) Curr. Opin. Pulm. Med. , vol.17 , pp. 355-361
    • Mouratis, M.A.1    Aidinis, V.2
  • 7
    • 84863296032 scopus 로고    scopus 로고
    • The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury
    • Funke, M., Zhao, Z., Xu, Y., Chun, J., and Tager, A. M. (2012) The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury. Am. J. Respir. Cell Mol. Biol. 46, 355-364.
    • (2012) Am. J. Respir. Cell Mol. Biol. , vol.46 , pp. 355-364
    • Funke, M.1    Zhao, Z.2    Xu, Y.3    Chun, J.4    Tager, A.M.5
  • 9
    • 49949098676 scopus 로고    scopus 로고
    • Two pathways for lysophosphatidic acid production
    • Aoki, J., Inoue, A., and Okudaira, S. (2008) Two pathways for lysophosphatidic acid production. Biochim. Biophys. Acta 1781, 513-518.
    • (2008) Biochim. Biophys. Acta. , vol.1781 , pp. 513-518
    • Aoki, J.1    Inoue, A.2    Okudaira, S.3
  • 11
    • 3242696730 scopus 로고    scopus 로고
    • Physiological and pathological actions of sphingosine 1-phosphate. Semin
    • Hla, T. (2004) Physiological and pathological actions of sphingosine 1-phosphate. Semin. Cell Dev. Biol. 15, 513-520.
    • (2004) Cell Dev. Biol. , vol.15 , pp. 513-520
    • Hla, T.1
  • 12
    • 77949470760 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 induces transdifferentiation of myoblasts into myofibroblasts via upregulation of sphingosine kinase-1/S1P3 axis
    • Cencetti, F., Bernacchioni, C., Nincheri, P., Donati, C., and Bruni, P. (2010) Transforming growth factor-beta1 induces transdifferentiation of myoblasts into myofibroblasts via upregulation of sphingosine kinase-1/S1P3 axis. Mol. Biol. Cell 21, 1111-1124.
    • (2010) Mol. Biol. Cell , vol.21 , pp. 1111-1124
    • Cencetti, F.1    Bernacchioni, C.2    Nincheri, P.3    Donati, C.4    Bruni, P.5
  • 13
    • 78649729538 scopus 로고    scopus 로고
    • Prolonged exposure to sphingosine 1-phosphate receptor-1 agonists exacerbates vascular leak, fibrosis, and mortality after lung injury
    • Shea, B. S., Brooks, S. F., Fontaine, B. A., Chun, J., Luster, A. D., and Tager, A. M. (2010) Prolonged exposure to sphingosine 1-phosphate receptor-1 agonists exacerbates vascular leak, fibrosis, and mortality after lung injury. Am. J. Respir. Cell Mol. Biol. 43, 662-673.
    • (2010) Am. J. Respir. Cell Mol. Biol. , vol.43 , pp. 662-673
    • Shea, B.S.1    Brooks, S.F.2    Fontaine, B.A.3    Chun, J.4    Luster, A.D.5    Tager, A.M.6
  • 16
    • 0023914820 scopus 로고
    • Simple method of estimating severity of pulmonary fibrosis on a numerical scale
    • Ashcroft, T., Simpson, J. M., and Timbrell, V. (1988) Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J. Clin. Pathol. 41, 467-470.
    • (1988) J. Clin. Pathol. , vol.41 , pp. 467-470
    • Ashcroft, T.1    Simpson, J.M.2    Timbrell, V.3
  • 19
    • 79551628419 scopus 로고    scopus 로고
    • Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: Role of sphingosine kinase 1 and S1P lyase
    • Berdyshev, E. V., Gorshkova, I., Usatyuk, P., Kalari, S., Zhao, Y., Pyne, N. J., Pyne, S., Sabbadini, R. A., Garcia, J. G., and Natarajan, V. (2011) Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyase. PLoS One 6, e16571.
    • (2011) PLoS One , vol.6
    • Berdyshev, E.V.1    Gorshkova, I.2    Usatyuk, P.3    Kalari, S.4    Zhao, Y.5    Pyne, N.J.6    Pyne, S.7    Sabbadini, R.A.8    Garcia, J.G.9    Natarajan, V.10
  • 20
    • 58849162410 scopus 로고    scopus 로고
    • SNPinProbe-1.0: A database for filtering out probes in the Affymetrix GeneChip human exon 1.0 ST array potentially affected by SNPs
    • Duan, S., Zhang, W., Bleibel, W. K., Cox, N. J., and Dolan, M. E. (2008) SNPinProbe-1.0: a database for filtering out probes in the Affymetrix GeneChip human exon 1.0 ST array potentially affected by SNPs. Bioinformation 2, 469-470.
    • (2008) Bioinformation , vol.2 , pp. 469-470
    • Duan, S.1    Zhang, W.2    Bleibel, W.K.3    Cox, N.J.4    Dolan, M.E.5
  • 21
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • U. S. A.
    • Tusher, V. G., Tibshirani, R., and Chu, G. (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. U. S. A. 98, 5116-5121.
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 23
    • 33947370516 scopus 로고    scopus 로고
    • Significance of pulmonary arterial pressure and diffusion capacity of the lung as prognosticator in patients with idiopathic pulmonary fibrosis
    • Hamada, K., Nagai, S., Tanaka, S., Handa, T., Shigematsu, M., Nagao, T., Mishima, M., Kitaichi, M., and Izumi, T. (2007) Significance of pulmonary arterial pressure and diffusion capacity of the lung as prognosticator in patients with idiopathic pulmonary fibrosis. Chest 131, 650-656.
    • (2007) Chest , vol.131 , pp. 650-656
    • Hamada, K.1    Nagai, S.2    Tanaka, S.3    Handa, T.4    Shigematsu, M.5    Nagao, T.6    Mishima, M.7    Kitaichi, M.8    Izumi, T.9
  • 24
    • 78649403525 scopus 로고    scopus 로고
    • SKI-II, an inhibitor of sphingosine kinase, ameliorates antigen-induced bronchial smooth muscle hyperresponsiveness, but not airway inflammation, in mice
    • Chiba, Y., Takeuchi, H., Sakai, H., and Misawa, M. (2010) SKI-II, an inhibitor of sphingosine kinase, ameliorates antigen-induced bronchial smooth muscle hyperresponsiveness, but not airway inflammation, in mice. J. Pharmacol. Sci. 114, 304-310.
    • (2010) J. Pharmacol. Sci. , vol.114 , pp. 304-310
    • Chiba, Y.1    Takeuchi, H.2    Sakai, H.3    Misawa, M.4
  • 27
    • 0026101053 scopus 로고
    • Analysis of local mRNA expression for extracellular matrix proteins and growth factors using in situ hybridization in fibroproliferative lung disorders
    • Limper, A. H., Broekelmann, T. J., Colby, T. V., Malizia, G., and McDonald, J. A. (1991) Analysis of local mRNA expression for extracellular matrix proteins and growth factors using in situ hybridization in fibroproliferative lung disorders. Chest 99, 55S-56S.
    • (1991) Chest , vol.99
    • Limper, A.H.1    Broekelmann, T.J.2    Colby, T.V.3    Malizia, G.4    McDonald, J.A.5
  • 28
    • 1242306647 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in lung development and disease
    • Bartram, U., and Speer, C. P. (2004) The role of transforming growth factor beta in lung development and disease. Chest 125, 754-765.
    • (2004) Chest , vol.125 , pp. 754-765
    • Bartram, U.1    Speer, C.P.2
  • 31
    • 33947314618 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate metabolism and intestinal tumorigenesis: Lipid signaling strikes again
    • Oskouian, B., and Saba, J. (2007) Sphingosine-1-phosphate metabolism and intestinal tumorigenesis: lipid signaling strikes again. Cell Cycle 6, 522-527.
    • (2007) Cell Cycle , vol.6 , pp. 522-527
    • Oskouian, B.1    Saba, J.2
  • 32
    • 84856066049 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition
    • Milara, J., Navarro, R., Juan, G., Peiró T, Serrano, A., Ramón, M., Morcillo, E., Cortijo, J. (2012) Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition. Thorax 67, 147- 156.
    • (2012) Thorax , vol.67 , pp. 147-156
    • Milara, J.1    Navarro, R.2    Juan, G.3    Peiró, T.4    Serrano, A.5    Ramón, M.6    Morcillo, E.7    Cortijo, J.8
  • 36
    • 78149436318 scopus 로고    scopus 로고
    • Acid sphingomyelinase deficiency attenuates bleomycin-induced lung inflammation and fibrosis in mice
    • Dhami, R., He, X., and Schuchman, E. H. (2010) Acid sphingomyelinase deficiency attenuates bleomycin-induced lung inflammation and fibrosis in mice. Cell. Physiol. Biochem. 26, 749-760.
    • (2010) Cell. Physiol. Biochem. , vol.26 , pp. 749-760
    • Dhami, R.1    He, X.2    Schuchman, E.H.3
  • 38
    • 84874670502 scopus 로고    scopus 로고
    • Characterization of isoenzymes-selective inhibitors of human sphingosine kinases
    • Gao, P., Peterson, Y. K., Smith, R. A., and Smith, C. D. (2012) Characterization of isoenzymes-selective inhibitors of human sphingosine kinases. PLoS ONE 7, e44543.
    • (2012) PLoS ONE , vol.7
    • Gao, P.1    Peterson, Y.K.2    Smith, R.A.3    Smith, C.D.4
  • 41
    • 2642580994 scopus 로고    scopus 로고
    • Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: Roles for cortactin and myosin light chain kinase
    • Dudek, S. M., Jacobson, J. R., Chiang, E. T., Birukov, K. G., Wang, P., Zhan, X., and Garcia, J. G. (2004) Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase. J. Biol. Chem. 279, 24692-24700.
    • (2004) J. Biol. Chem. , vol.279 , pp. 24692-24700
    • Dudek, S.M.1    Jacobson, J.R.2    Chiang, E.T.3    Birukov, K.G.4    Wang, P.5    Zhan, X.6    Garcia, J.G.7
  • 45
    • 84866379271 scopus 로고    scopus 로고
    • Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate
    • Kharel, Y., Raje, M., Gao, M., Gellett, A. M., Tomsig, J. L., Lynch, K. R., and Santos, W. L. (2012) Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate. Biochem. J. 447, 149-157.
    • (2012) Biochem. J. , vol.447 , pp. 149-157
    • Kharel, Y.1    Raje, M.2    Gao, M.3    Gellett, A.M.4    Tomsig, J.L.5    Lynch, K.R.6    Santos, W.L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.