ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis

Journal of Lipid Research

Volumn 56, Issue 4, 2015, Pages 898-908

  Siow, Deanna ^a   Sunkara, Manjula ^b   Dunn, Teresa M ^c   Morris, Andrew J ^b   Wattenberg, Binks ^a  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

Author keywords

Asthma; Ceramides; Endoplasmic reticulum; Enzymology enzyme regulation; Lung; Orm; ORM1 (saccharomyces cerevisiae) like protein; Sphingosine phosphate

Indexed keywords

CELL PROTEIN; ISOPROTEIN; PROTEIN ORMDL1; PROTEIN ORMDL2; PROTEIN ORMDL3; SERINE PALMITOYLTRANSFERASE; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; ORMDL3 PROTEIN, HUMAN; SMALL INTERFERING RNA; SPHINGOLIPID;

ARTICLE; CELL IMMORTALIZATION; CELL MEMBRANE PERMEABILITY; COMPLEX FORMATION; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; HELA CELL LINE; HUMAN; HUMAN BRONCHIAL EPITHELIAL CELL; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA ISOLATION; SPHINGOLIPID METABOLISM; STEADY STATE; STOICHIOMETRY; ANIMAL; ASTHMA; BIOSYNTHESIS; BRONCHUS; CYTOLOGY; DEFICIENCY; ENZYMOLOGY; GENE EXPRESSION; GENE SILENCING; GENETICS; METABOLISM; MOUSE; PHENOTYPE;

ANIMALS; ASTHMA; BRONCHI; EPITHELIAL CELLS; GENE EXPRESSION; GENE SILENCING; HELA CELLS; HUMANS; MEMBRANE PROTEINS; MICE; PHENOTYPE; RNA, SMALL INTERFERING; SERINE C-PALMITOYLTRANSFERASE; SPHINGOLIPIDS;

EID: 84927534633     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M057539     Document Type: Article

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