Systemic administration of sphingosine-1-phosphate increases bronchial hyperresponsiveness in the mouse

American Journal of Respiratory Cell and Molecular Biology

Volumn 42, Issue 5, 2010, Pages 572-577

  Roviezzo, Fiorentina ^a   D'Agostino, Bruno ^b   Brancaleone, Vincenzo ^a   De Gruttola, Luana ^a   Bucci, Mariarosaria ^a   De Dominicis, Gianfranco ^c   Orlotti, Donatella ^b   D'Aiuto, Elena ^b   De Palma, Raffaele ^b   Rossi, Francesco ^b   Sorrentino, Raffaella ^a   Cirino, Giuseppe ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b SECOND UNIVERSITY OF NAPLES   (Italy)

^c CARDARELLI HOSPITAL   (Italy)

Author keywords

Airway; Bronchi; Cytokines; Sphingosine 1 phosphate

Indexed keywords

CHEMOKINE RECEPTOR CCR3; CYTOKINE; GAMMA INTERFERON; IL 12P19; INTERLEUKIN 12P35; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; RANTES; SPHINGOSINE 1 PHOSPHATE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; LYSOPHOSPHOLIPID; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRONCHUS HYPERREACTIVITY; CHOLINERGIC ACTIVITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE TIME EFFECT RELATION; IN VITRO STUDY; LUNG RESISTANCE; MAST CELL; MOLECULAR MECHANICS; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; AIRWAY RESISTANCE; ANIMAL; BAGG ALBINO MOUSE; BRONCHUS; CELL MOTION; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; EOSINOPHIL; LUNG LAVAGE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; TIME;

MUS;

AIRWAY RESISTANCE; ANIMALS; BRONCHI; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CELL MOVEMENT; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; EOSINOPHILS; LYSOPHOSPHOLIPIDS; MAST CELLS; MICE; MICE, INBRED BALB C; SPHINGOSINE; TIME FACTORS;

EID: 77951638132     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2009-0108OC     Document Type: Article

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